Agents-K1: Towards Agent-native Knowledge Orchestration

Current LLM-based research agents have advanced through agent orchestration, yet largely overlook scientific knowledge orchestration. Existing works often reduce papers to abstracts, surface mentions, and flat \texttt{cites} edges, omitting key entities, claims, evidence, mechanisms, and method lineages essential for scientific reasoning. To this end, we introduce \textbf{Agents-K1}, an end-to-end knowledge orchestration pipeline that converts raw documents into agent-native scientific knowledge graphs. Agents-K1 integrates three components under a unifying theoretical foundation: a multimodal parser whose five-module schema captures entities, multimodal evidence, citations, and typed inter-entity relations across the full paper rather than abstracts alone; a 4B information-extraction backbone trained with GRPO under a rule-based reward; and a graphanything CLI, a tri-source agent interface that unifies web search, multimodal graph retrieval, and cross-document traversal. On top of this, we process 2.46 million scientific papers across six subjects to produce \textbf{Scholar-KG}, of which we release a one-million-paper subset, and the full Scholar-KG is accessible via the SCP link below. The same pipeline can be extended to general-domain corpora and to schema-conformant data synthesis. Extensive experiments demonstrate that Agents-K1 achieves superior performance in scientific information extraction, knowledge graph construction, and multi-hop scientific reasoning.

LabVLA: Grounding Vision-Language-Action Models in Scientific Laboratories

Scientific laboratories increasingly rely on AI systems to reason about experiments, but the physical act of doing science remains largely outside their reach. AI can help read literature, generate hypotheses, and plan protocols, yet the execution of those protocols at the bench still requires a human operator. Vision-Language-Action (VLA) models provide one possible interface between written protocols and robot execution, but existing policies are trained mostly on household and tabletop demonstrations and rarely encounter the instruments, transparent liquids, or fixed protocol workflows found in scientific laboratories. Closing this gap requires both laboratory-specific supervision and a unified learning framework that can accommodate the diverse robot embodiments used to execute experimental protocols. We therefore identify data and embodiment as central bottlenecks alongside model design. To address the data side, we build RoboGenesis, a simulation-based workflow and data engine that composes configured laboratory workflows from atomic skills, validates and filters rollouts, and exports structured demonstrations across supported robot profiles. On the policy side, we present LabVLA, trained with a two-stage recipe: FAST action token pretraining first makes the Qwen3-VL-4B-Instruct backbone action aware before any continuous control is learned, and flow matching posttraining then attaches a DiT action expert under knowledge insulation. On the LabUtopia benchmark, LabVLA achieves the highest average success rate among all evaluated baselines under both in-distribution and out-of-distribution settings.

Self-Harness: Harnesses That Improve Themselves

The performance of LLM-based agents is jointly shaped by their base models and the harnesses that mediate their interaction with the environment. Because different models exhibit distinct behaviors, effective harness design is inherently model-specific. Yet agent harnesses are still largely engineered by human experts, a paradigm that scales poorly as modern LLMs become increasingly diverse and rapidly evolving. In this paper, we introduce Self-Harness, a new paradigm in which an LLM-based agent improves its own operating harness, without relying on human engineers or stronger external agents. We operationalize Self-Harness as an iterative loop with three stages: Weakness Mining, which identifies model-specific failure patterns from execution traces; Harness Proposal, which generates diverse yet minimal harness modifications tied to these failures; and Proposal Validation, which accepts candidate edits only after regression testing. We instantiate Self-Harness on Terminal-Bench-2.0 using a minimal initial harness and three base models from diverse families: MiniMax M2.5, Qwen3.5-35B-A3B, and GLM-5. Across all three models, Self-Harness consistently improves performance, with held-out pass rates increasing from 40.5% to 61.9%, 23.8% to 38.1%, and 42.9% to 57.1%, respectively. Qualitative analyses further show that Self-Harness does not simply add generic instructions, but effectively turns model-specific weaknesses into concrete, executable harness changes. These results suggest a path toward LLM-based agents that are not merely shaped by their harnesses, but can also participate in reshaping them.

MLEvolve: A Self-Evolving Framework for Automated Machine Learning Algorithm Discovery

Large language model (LLM) agents are increasingly applied to long-horizon tasks such as scientific discovery and machine learning engineering (MLE), where sustained self-evolution becomes a key capability. However, existing MLE agents suffer from inter-branch information isolation, memoryless search, and lack of hierarchical control, which together hinder long-horizon optimization. We present MLEvolve, an LLM-based self-evolving multi-agent framework for end-to-end machine learning algorithm discovery. By extending tree search to Progressive MCGS, MLEvolve enables cross-branch information flow through graph-based reference edges and gradually shifts the search from broad exploration to focused exploitation with an entropy-inspired progressive schedule. To allow the agent to evolve with accumulated experience, we introduce Retrospective Memory, which combines a cold-start domain knowledge base with a dynamic global memory for task-specific experience retrieval and reuse. For stable long-horizon iteration, we further decouple strategic planning from code generation with adaptive coding modes. Evaluation on MLE-Bench shows that MLEvolve achieves state-of-the-art performance across multiple dimensions including average medal rate and valid submission rate under a 12-hour budget (half the standard runtime). Moreover, MLEvolve also outperforms specialized algorithm discovery methods including AlphaEvolve on mathematical algorithm optimization tasks, demonstrating strong cross-domain generalization. Our code is available at https://github.com/InternScience/MLEvolve.

SCI-PRM: A Tool Aware Process Reward Model for Scientific Reasoning Verification

While Process Reward Models (PRMs) have achieved remarkable success in mathematical reasoning, their application in complex scientific domains-such as biology, chemistry, and physics remains largely unexplored. Scientific problems demand not only logical rigor but also factual consistency and the precise usage of domain-specific tools, areas where current models often suffer from hallucinations and lack of verification. In this paper, we first construct SCIPRM70K, a large-scale dataset featuring Chain-of-Tool trajectories that explicitly interleave reasoning with the execution of scientific tools. Building upon this, we train an efficient reward model called Sci-PRM to provide fine-grained supervision on tool selection, execution accuracy, and result interpretation at each step in one inference. Experiments demonstrate that Sci-PRM significantly enhances foundation models in two key aspects: (1) it enables effective test-time scaling via Best-of-N selection; and (2) when integrated into Reinforcement Learning, it serves as a dense reward signal that mitigates the critical issue of advantage disappearance, allowing the model to break through existing performance ceilings.

Trans2Occ: Voxel Occupancy Estimation and Grasp for Transparent Objects from Simulation to Reality

Transparent objects remain challenging for robotic perception due to unreliable depth sensing caused by refraction and reflection. While prior approaches rely on multi-view reconstruction or depth completion, they are often difficult to scale or deploy in real-world robotic systems. In this paper, we present a practical framework for transparent object perception and manipulation based on single-view RGB input. Our approach predicts voxel-space occupancy directly from a single image, providing a geometry-aware representation that supports downstream robotic grasping. To enable large-scale training, we construct a simulation pipeline that generates paired RGB images and voxel occupancy annotations under diverse materials and lighting conditions. We demonstrate that the predicted occupancy representation is robust to domain shifts and transfers effectively from simulation to real-world robotic setups without fine-tuning. A simple rule-based grasping strategy built on top of the occupancy further achieves reliable grasp performance on transparent objects. Extensive experiments in both simulation and real-world environments show that our framework provides accurate 3D understanding and enables practical manipulation of transparent objects. These results suggest that single-view occupancy prediction offers a scalable and effective solution for transparent object perception in robotics.

AMix-2: Establishing Protein as a Native Modality in Large Language Models

We present AMix-2, a protein-text foundation model that establishes protein as a native modality in large language models (LLMs), unifying protein understanding and sequence design within a single foundation model. AMix-2 is built upon two key ideas: (1) a unified protein-text formulation that embeds natural language and protein sequence in a shared token space, enabling one model to perform biological reasoning and conditional design instead of separate downstream task-specialized models; and (2) a block-wise diffusion language modeling backbone that combines causal generation across blocks with bidirectional context and iterative refinement within blocks. This scheme better matches the intrinsic nature of proteins than a strict left-to-right factorization. To evaluate protein foundation models under realistic generalization settings, we further introduce ProteinArena, a comprehensive benchmark with time-aware and homology-aware protocols across various understanding and design tasks, and with baselines covering classical bioinformatics tools, protein-specialized models and LLMs. On ProteinArena, AMix-2 outperforms frontier LLMs and demonstrates competitive performance to task-specific protein models. Controlled experiments further show that the diffusion-based paradigm generally surpasses its autoregressive counterpart, highlighting the advantage of flexible generation order for protein sequences. We release both AMix-2 and ProteinArena to facilitate open research in protein foundation models.

OmniMatBench: A Human-Calibrated Multimodal Reasoning Benchmark Across 19 Materials Science Subfields

As multimodal language models play an increasingly important role in scientific research, materials science offers a critical testbed due to its interdisciplinary, multimodal, and application-driven nature. However, existing materials benchmarks mainly focus on property prediction, knowledge QA, or characterization understanding, leaving the broader reasoning process from materials knowledge to application underexplored. To fill this gap, we present OmniMatBench, a human-calibrated multimodal reasoning benchmark for materials science. OmniMatBench contains 3,171 expert-curated QA and calculation problems across 19 materials-science subfields, spanning fundamental materials knowledge, structural and engineering materials, materials processing and manufacturing, and functional and applied materials. We evaluate 13 open-source and closed-source MLLMs and find that the best model achieves only a 0.372 overall score, revealing a substantial gap in current materials-science reasoning. Further analysis shows strong variation across subfields, fixed reasoning heuristics, uneven materials knowledge, and limited high-level knowledge application under formula-, retrieval-, and code-assisted settings. OmniMatBench provides crucial insights into the capabilities and limitations of current MLLMs and establishes a foundation for reliable AI assistants in materials-science research.

RealBench: Benchmarking Data-Driven Numerical Weather Forecasting Under Operational Conditions and Extreme Event Challenges

Accurate evaluation of weather forecasting models is critical for their reliable deployment in real-world applications. However, existing benchmarks predominantly rely on reanalysis products such as ERA5, which are generated through delayed data assimilation and do not reflect the constraints of real-time operational forecasting, thereby resulting in a systematic mismatch between benchmark performance and real-world forecasting. In this work, we introduce RealBench, a next-generation benchmark for AI weather forecasting that emphasizes realistic evaluation under operational conditions. RealBench features a strictly out-of-distribution test set spanning 2025 to eliminate data leakage and capture recent atmospheric regimes. It integrates multiple data sources, including low-latency operational analysis and a large-scale global in-situ observation dataset comprising over 10,000 stations, enabling direct evaluation against real atmospheric measurements. Beyond standard global metrics, RealBench provides a comprehensive evaluation framework for high-impact extreme events, including heatwaves, cold surges, and tropical cyclones, using event-specific metrics that better reflect real-world forecasting priorities. The evaluation results reveal substantial discrepancies between reanalysis-based metrics and real-world performance, particularly concerning extreme events. By highlighting the limitations of existing benchmarks, this work establishes a more faithful and operationally relevant evaluation paradigm, providing a rigorous foundation for advancing next-generation AI weather forecasting systems. The benchmark implementation is available at: https://github.com/lixruize-del/NWP-Benchmark.

Are Tools Always Beneficial? Learning to Invoke Tools Adaptively for Dual-Mode Multimodal LLM Reasoning

Tool-augmented reasoning has emerged as a promising direction for enhancing the reasoning capabilities of multimodal large language models (MLLMs). However, existing studies mainly focus on enabling models to perform tool invocation, while neglecting the necessity of invoking tools. We argue that tool usage is not always beneficial, as redundant or inappropriate invocations largely increase reasoning overhead and even mislead model predictions. To address this issue, we introduce AutoTool, a model that adaptively decides whether to invoke tools according to the characteristics of each query. Within a reinforcement learning framework, we design an explicit dual-mode reasoning strategy with mode-specific reward functions to guide the model toward producing accurate responses. Moreover, to prevent premature bias toward a single reasoning mode, AutoTool jointly explores and balances tool-assisted and text-centric reasoning throughout training, and promotes free exploration in later stages. Extensive experiments demonstrate that AutoTool exhibits outstanding performance and high efficiency, yielding a 21.8\% accuracy gain on V* benchmark compared to the base model, and a 44.9\% improvement in efficiency over existing tool-augmented methods on POPE benchmark. Code is available at https://github.com/MQinghe/AutoTool.