GIP-RAG: An Evidence-Grounded Retrieval-Augmented Framework for Interpretable Gene Interaction and Pathway Impact Analysis

Understanding mechanistic relationships among genes and their impacts on biological pathways is essential for elucidating disease mechanisms and advancing precision medicine. Despite the availability of extensive molecular interaction and pathway data in public databases, integrating heterogeneous knowledge sources and enabling interpretable multi-step reasoning across biological networks remain challenging. We present GIP-RAG (Gene Interaction Prediction through Retrieval-Augmented Generation), a computational framework that combines biomedical knowledge graphs with large language models (LLMs) to infer and interpret gene interactions. The framework constructs a unified gene interaction knowledge graph by integrating curated data from KEGG, WikiPathways, SIGNOR, Pathway Commons, and PubChem. Given user-specified genes, a query-driven module retrieves relevant subgraphs, which are incorporated into structured prompts to guide LLM-based stepwise reasoning. This enables identification of direct and indirect regulatory relationships and generation of mechanistic explanations supported by biological evidence. Beyond pairwise interactions, GIP-RAG includes a pathway-level functional impact module that simulates propagation of gene perturbations through signaling networks and evaluates potential pathway state changes. Evaluation across diverse biological scenarios demonstrates that the framework generates consistent, interpretable, and evidence-supported insights into gene regulatory mechanisms. Overall, GIP-RAG provides a general and interpretable approach for integrating knowledge graphs with retrieval-augmented LLMs to support mechanistic reasoning in complex molecular systems.

Event-Centric Human Value Understanding in News-Domain Texts: An Actor-Conditioned, Multi-Granularity Benchmark

Existing human value datasets do not directly support value understanding in factual news: many are actor-agnostic, rely on isolated utterances or synthetic scenarios, and lack explicit event structure or value direction. We present \textbf{NEVU} (\textbf{N}ews \textbf{E}vent-centric \textbf{V}alue \textbf{U}nderstanding), a benchmark for \emph{actor-conditioned}, \emph{event-centric}, and \emph{direction-aware} human value recognition in factual news. NEVU evaluates whether models can identify value cues, attribute them to the correct actor, and determine value direction from grounded evidence. Built from 2{,}865 English news articles, NEVU organizes annotations at four semantic unit levels (\textbf{Subevent}, \textbf{behavior-based composite event}, \textbf{story-based composite event}, and \textbf{Article}) and labels \mbox{(unit, actor)} pairs for fine-grained evaluation across local and composite contexts. The annotations are produced through an LLM-assisted pipeline with staged verification and targeted human auditing. Using a hierarchical value space with \textbf{54} fine-grained values and \textbf{20} coarse-grained categories, NEVU covers 45{,}793 unit--actor pairs and 168{,}061 directed value instances. We provide unified baselines for proprietary and open-source LLMs, and find that lightweight adaptation (LoRA) consistently improves open-source models, showing that although NEVU is designed primarily as a benchmark, it also supports supervised adaptation beyond prompting-only evaluation. Data availability is described in Appendix~\ref{app:data_code_availability}.

Edge-Assisted Multi-Robot Visual-Inertial SLAM with Efficient Communication

The integration of cloud computing and edge computing is an effective way to achieve global consistent and real-time multi-robot Simultaneous Localization and Mapping (SLAM). Cloud computing effectively solves the problem of limited computing, communication and storage capacity of terminal equipment. However, limited bandwidth and extremely long communication links between terminal devices and the cloud result in serious performance degradation of multi-robot SLAM systems. To reduce the computational cost of feature tracking and improve the real-time performance of the robot, a lightweight SLAM method of optical flow tracking based on pyramid IMU prediction is proposed. On this basis, a centralized multi-robot SLAM system based on a robot-edge-cloud layered architecture is proposed to realize real-time collaborative SLAM. It avoids the problems of limited on-board computing resources and low execution efficiency of single robot. In this framework, only the feature points and keyframe descriptors are transmitted and lossless encoding and compression are carried out to realize real-time remote information transmission with limited bandwidth resources. This design reduces the actual bandwidth occupied in the process of data transmission, and does not cause the loss of SLAM accuracy caused by data compression. Through experimental verification on the EuRoC dataset, compared with the current most advanced local feature compression method, our method can achieve lower data volume feature transmission, and compared with the current advanced centralized multi-robot SLAM scheme, it can achieve the same or better positioning accuracy under low computational load.

Beyond Test-Time Training: Learning to Reason via Hardware-Efficient Optimal Control

Associative memory has long underpinned the design of sequential models. Beyond recall, humans reason by projecting future states and selecting goal-directed actions, a capability that modern language models increasingly require but do not natively encode. While prior work uses reinforcement learning or test-time training, planning remains external to the model architecture. We formulate reasoning as optimal control and introduce the Test-Time Control (TTC) layer, which performs finite-horizon LQR planning over latent states at inference time, represents a value function within neural architectures, and leverages it as the nested objective to enable planning before prediction. To ensure scalability, we derive a hardware-efficient LQR solver based on a symplectic formulation and implement it as a fused CUDA kernel, enabling parallel execution with minimal overhead. Integrated as an adapter into pretrained LLMs, TTC layers improve mathematical reasoning performance by up to +27.8% on MATH-500 and 2-3x Pass@8 improvements on AMC and AIME, demonstrating that embedding optimal control as an architectural component provides an effective and scalable mechanism for reasoning beyond test-time training.

Diff-Muscle: Efficient Learning for Musculoskeletal Robotic Table Tennis

Musculoskeletal robots provide superior advantages in flexibility and dexterity, positioning them as a promising frontier towards embodied intelligence. However, current research is largely confined to relative simple tasks, restricting the exploration of their full potential in multi-segment coordination. Furthermore, efficient learning remains a challenge, primarily due to the high-dimensional action space and inherent overactuated structures. To address these challenges, we propose Diff-Muscle, a musculoskeletal robot control algorithm that leverages differential flatness to reformulate policy learning from the redundant muscle-activation space into a significantly lower-dimensional joint space. Furthermore, we utilize the highly dynamic robotic table tennis task to evaluate our algorithm. Specifically, we propose a hierarchical reinforcement learning framework that integrates a Kinematics-based Muscle Actuation Controller (K-MAC) with high-level trajectory planning, enabling a musculoskeletal robot to perform dexterous and precise rallies. Experimental results demonstrate that Diff-Muscle significantly outperforms state-of-the-art baselines in success rates while maintaining minimal muscle activation. Notably, the proposed framework successfully enables the musculoskeletal robots to achieve continuous rallies in a challenging dual-robot setting.

How Well Do Multimodal Models Reason on ECG Signals?

While multimodal large language models offer a promising solution to the "black box" nature of health AI by generating interpretable reasoning traces, verifying the validity of these traces remains a critical challenge. Existing evaluation methods are either unscalable, relying on manual clinician review, or superficial, utilizing proxy metrics (e.g. QA) that fail to capture the semantic correctness of clinical logic. In this work, we introduce a reproducible framework for evaluating reasoning in ECG signals. We propose decomposing reasoning into two distinct, components: (i) Perception, the accurate identification of patterns within the raw signal, and (ii) Deduction, the logical application of domain knowledge to those patterns. To evaluate Perception, we employ an agentic framework that generates code to empirically verify the temporal structures described in the reasoning trace. To evaluate Deduction, we measure the alignment of the model's logic against a structured database of established clinical criteria in a retrieval-based approach. This dual-verification method enables the scalable assessment of "true" reasoning capabilities.

CUDA Agent: Large-Scale Agentic RL for High-Performance CUDA Kernel Generation

GPU kernel optimization is fundamental to modern deep learning but remains a highly specialized task requiring deep hardware expertise. Despite strong performance in general programming, large language models (LLMs) remain uncompetitive with compiler-based systems such as torch.compile for CUDA kernel generation. Existing CUDA code generation approaches either rely on training-free refinement or fine-tune models within fixed multi-turn execution-feedback loops, but both paradigms fail to fundamentally improve the model's intrinsic CUDA optimization ability, resulting in limited performance gains. We present CUDA Agent, a large-scale agentic reinforcement learning system that develops CUDA kernel expertise through three components: a scalable data synthesis pipeline, a skill-augmented CUDA development environment with automated verification and profiling to provide reliable reward signals, and reinforcement learning algorithmic techniques enabling stable training. CUDA Agent achieves state-of-the-art results on KernelBench, delivering 100\%, 100\%, and 92\% faster rate over torch.compile on KernelBench Level-1, Level-2, and Level-3 splits, outperforming the strongest proprietary models such as Claude Opus 4.5 and Gemini 3 Pro by about 40\% on the hardest Level-3 setting.

veScale-FSDP: Flexible and High-Performance FSDP at Scale

Fully Sharded Data Parallel (FSDP), also known as ZeRO, is widely used for training large-scale models, featuring its flexibility and minimal intrusion on model code. However, current FSDP systems struggle with structure-aware training methods (e.g., block-wise quantized training) and with non-element-wise optimizers (e.g., Shampoo and Muon) used in cutting-edge models (e.g., Gemini, Kimi K2). FSDP's fixed element- or row-wise sharding formats conflict with the block-structured computations. In addition, today's implementations fall short in communication and memory efficiency, limiting scaling to tens of thousands of GPUs. We introduce veScale-FSDP, a redesigned FSDP system that couples a flexible sharding format, RaggedShard, with a structure-aware planning algorithm to deliver both flexibility and performance at scale. veScale-FSDP natively supports efficient data placement required by FSDP, empowering block-wise quantization and non-element-wise optimizers. As a result, veScale-FSDP achieves 5~66% higher throughput and 16~30% lower memory usage than existing FSDP systems, while scaling efficiently to tens of thousands of GPUs.

Dual-Granularity Contrastive Reward via Generated Episodic Guidance for Efficient Embodied RL

Designing suitable rewards poses a significant challenge in reinforcement learning (RL), especially for embodied manipulation. Trajectory success rewards are suitable for human judges or model fitting, but the sparsity severely limits RL sample efficiency. While recent methods have effectively improved RL via dense rewards, they rely heavily on high-quality human-annotated data or abundant expert supervision. To tackle these issues, this paper proposes Dual-granularity contrastive reward via generated Episodic Guidance (DEG), a novel framework to seek sample-efficient dense rewards without requiring human annotations or extensive supervision. Leveraging the prior knowledge of large video generation models, DEG only needs a small number of expert videos for domain adaptation to generate dedicated task guidance for each RL episode. Then, the proposed dual-granularity reward that balances coarse-grained exploration and fine-grained matching, will guide the agent to efficiently approximate the generated guidance video sequentially in the contrastive self-supervised latent space, and finally complete the target task. Extensive experiments on 18 diverse tasks across both simulation and real-world settings show that DEG can not only serve as an efficient exploration stimulus to help the agent quickly discover sparse success rewards, but also guide effective RL and stable policy convergence independently.

ABot-N0: Technical Report on the VLA Foundation Model for Versatile Embodied Navigation

Embodied navigation has long been fragmented by task-specific architectures. We introduce ABot-N0, a unified Vision-Language-Action (VLA) foundation model that achieves a ``Grand Unification'' across 5 core tasks: Point-Goal, Object-Goal, Instruction-Following, POI-Goal, and Person-Following. ABot-N0 utilizes a hierarchical ``Brain-Action'' architecture, pairing an LLM-based Cognitive Brain for semantic reasoning with a Flow Matching-based Action Expert for precise, continuous trajectory generation. To support large-scale learning, we developed the ABot-N0 Data Engine, curating 16.9M expert trajectories and 5.0M reasoning samples across 7,802 high-fidelity 3D scenes (10.7 $\text{km}^2$). ABot-N0 achieves new SOTA performance across 7 benchmarks, significantly outperforming specialized models. Furthermore, our Agentic Navigation System integrates a planner with hierarchical topological memory, enabling robust, long-horizon missions in dynamic real-world environments.