Efficient Agentic Reasoning Through Self-Regulated Simulative Planning

How should an agent decide when and how to plan? A dominant approach builds agents as reactive policies with adaptive computation (e.g., chain-of-thought), trained end-to-end expecting planning to emerge implicitly. Without control over the presence, structure, or horizon of planning, these systems dramatically increase reasoning length, yielding inefficient token use without reliable accuracy gains. We argue efficient agentic reasoning benefits from decomposing decision-making into three systems: simulative reasoning (System II) grounding deliberation in future-state prediction via a world model; self-regulation (System III) deciding when and how deeply to plan via a learned configurator; and reactive execution (System I) handling fine-grained action. Simulative reasoning provides unified planning across diverse tasks without per-domain engineering, while self-regulation ensures the planner is invoked only when needed. To test this, we develop SR$^2$AM (Self-Regulated Simulative Reasoning Agentic LLM), realizing both as distinct stages within an LLM's chain-of-thought, with the LLM as world model. We explore two instantiations: recording decisions from a prompted multi-module system (v0.1) and reconstructing structured plans from traces of pretrained reasoning LLMs (v1.0), trained via supervised then reinforcement learning (RL). Across math, science, tabular analysis, and web information seeking, v0.1-8B and v1.0-30B achieve Pass@1 competitive with 120-355B and 685B-1T parameter systems respectively, while v1.0-30B uses 25.8-95.3% fewer reasoning tokens than comparable agentic LLMs. RL increases average planning horizon by 22.8% while planning frequency grows only 2.0%, showing it learns to plan further ahead rather than more often. More broadly, learned self-regulation instantiates a principle we expect to extend beyond planning to how agents govern their own learning and adaptation.

Uniform Diffusion Models Revisited: Leave-One-Out Denoiser and Absorbing State Reformulation

Discrete diffusion models are often trained through clean-data prediction, but the prediction can be used in different ways to define the reverse dynamics. In Masked Diffusion Models (MDM) these choices largely coincide, whereas in Uniform Diffusion Models (UDM) they do not. We show that the standard plug-in bridge parameterization for UDM is not optimized by the denoising posterior, but by a leave-one-out posterior that predicts each clean token without using its own noisy observation. This identifies a mismatch between the plug-in ELBO and the usual cross-entropy denoising objective. We characterize the leave-one-out target and derive exact conversions between the denoiser, the leave-one-out posterior, and the score. These conversions allow us to disentangle parameterization and training objective. Our results also lead to inference improvements without any additional training through an informed predictor-corrector sampler and improved temperature sampling based on the leave-one-out predictor. We further introduce an absorbing-state reformulation of uniform diffusion that preserves the UDM joint law while decomposing it into masked-diffusion-like sampling operations, with simpler denoising posteriors, carry-over unmasking, and a natural remasking mechanism. On language modeling, leave-one-out parameterizations consistently improve UDM generation, while the absorbing construction matches or surpasses masked diffusion. These results suggest that the empirical gap between masked and uniform diffusion is driven less by the choice of marginals themselves than by parameterization and sampling design. The code and models can be found at https://github.com/samsongourevitch/rev_udm.

CocoaBench: Evaluating Unified Digital Agents in the Wild

LLM agents now perform strongly in software engineering, deep research, GUI automation, and various other applications, while recent agent scaffolds and models are increasingly integrating these capabilities into unified systems. Yet, most evaluations still test these capabilities in isolation, which leaves a gap for more diverse use cases that require agents to combine different capabilities. We introduce CocoaBench, a benchmark for unified digital agents built from human-designed, long-horizon tasks that require flexible composition of vision, search, and coding. Tasks are specified only by an instruction and an automatic evaluation function over the final output, enabling reliable and scalable evaluation across diverse agent infrastructures. We also present CocoaAgent, a lightweight shared scaffold for controlled comparison across model backbones. Experiments show that current agents remain far from reliable on CocoaBench, with the best evaluated system achieving only 45.1% success rate. Our analysis further points to substantial room for improvement in reasoning and planning, tool use and execution, and visual grounding.

Mobile-O: Unified Multimodal Understanding and Generation on Mobile Device

Unified multimodal models can both understand and generate visual content within a single architecture. Existing models, however, remain data-hungry and too heavy for deployment on edge devices. We present Mobile-O, a compact vision-language-diffusion model that brings unified multimodal intelligence to a mobile device. Its core module, the Mobile Conditioning Projector (MCP), fuses vision-language features with a diffusion generator using depthwise-separable convolutions and layerwise alignment. This design enables efficient cross-modal conditioning with minimal computational cost. Trained on only a few million samples and post-trained in a novel quadruplet format (generation prompt, image, question, answer), Mobile-O jointly enhances both visual understanding and generation capabilities. Despite its efficiency, Mobile-O attains competitive or superior performance compared to other unified models, achieving 74% on GenEval and outperforming Show-O and JanusFlow by 5% and 11%, while running 6x and 11x faster, respectively. For visual understanding, Mobile-O surpasses them by 15.3% and 5.1% averaged across seven benchmarks. Running in only ~3s per 512x512 image on an iPhone, Mobile-O establishes the first practical framework for real-time unified multimodal understanding and generation on edge devices. We hope Mobile-O will ease future research in real-time unified multimodal intelligence running entirely on-device with no cloud dependency. Our code, models, datasets, and mobile application are publicly available at https://amshaker.github.io/Mobile-O/

CellMaster: Collaborative Cell Type Annotation in Single-Cell Analysis

Single-cell RNA-seq (scRNA-seq) enables atlas-scale profiling of complex tissues, revealing rare lineages and transient states. Yet, assigning biologically valid cell identities remains a bottleneck because markers are tissue- and state-dependent, and novel states lack references. We present CellMaster, an AI agent that mimics expert practice for zero-shot cell-type annotation. Unlike existing automated tools, CellMaster leverages LLM-encoded knowledge (e.g., GPT-4o) to perform on-the-fly annotation with interpretable rationales, without pre-training or fixed marker databases. Across 9 datasets spanning 8 tissues, CellMaster improved accuracy by 7.1% over best-performing baselines (including CellTypist and scTab) in automatic mode. With human-in-the-loop refinement, this advantage increased to 18.6%, with a 22.1% gain on subtype populations. The system demonstrates particular strength in rare and novel cell states where baselines often fail. Source code and the web application are available at \href{https://github.com/AnonymousGym/CellMaster}{https://github.com/AnonymousGym/CellMaster}.

scPilot: Large Language Model Reasoning Toward Automated Single-Cell Analysis and Discovery

We present scPilot, the first systematic framework to practice omics-native reasoning: a large language model (LLM) converses in natural language while directly inspecting single-cell RNA-seq data and on-demand bioinformatics tools. scPilot converts core single-cell analyses, i.e., cell-type annotation, developmental-trajectory reconstruction, and transcription-factor targeting, into step-by-step reasoning problems that the model must solve, justify, and, when needed, revise with new evidence. To measure progress, we release scBench, a suite of 9 expertly curated datasets and graders that faithfully evaluate the omics-native reasoning capability of scPilot w.r.t various LLMs. Experiments with o1 show that iterative omics-native reasoning lifts average accuracy by 11% for cell-type annotation and Gemini-2.5-Pro cuts trajectory graph-edit distance by 30% versus one-shot prompting, while generating transparent reasoning traces explain marker gene ambiguity and regulatory logic. By grounding LLMs in raw omics data, scPilot enables auditable, interpretable, and diagnostically informative single-cell analyses. Code, data, and package are available at https://github.com/maitrix-org/scPilot

Retrieval-Aware Distillation for Transformer-SSM Hybrids

State-space models (SSMs) offer efficient sequence modeling but lag behind Transformers on benchmarks that require in-context retrieval. Prior work links this gap to a small set of attention heads, termed Gather-and-Aggregate (G&A), which SSMs struggle to reproduce. We propose *retrieval-aware distillation*, which converts a pretrained Transformer into a hybrid student by preserving only these retrieval-critical heads and distilling the rest into recurrent heads. We identify the essential heads via ablation on a synthetic retrieval task, producing a hybrid with sparse, non-uniform attention placement. We show that preserving **just 2% of attention heads recovers over 95% of teacher performance on retrieval-heavy tasks** (10 heads in a 1B model), requiring far fewer heads than hybrids that retain at least 25%. We further find that large recurrent states often compensate for missing retrieval: once retrieval is handled by these heads, the SSM backbone can be simplified with limited loss, even with an $8\times$ reduction in state dimension. By reducing both the attention cache and the SSM state, the resulting hybrid is $5$--$6\times$ more memory-efficient than comparable hybrids, closing the Transformer--SSM gap at a fraction of the memory cost.

FIRE-Bench: Evaluating Agents on the Rediscovery of Scientific Insights

Autonomous agents powered by large language models (LLMs) promise to accelerate scientific discovery end-to-end, but rigorously evaluating their capacity for verifiable discovery remains a central challenge. Existing benchmarks face a trade-off: they either heavily rely on LLM-as-judge evaluations of automatically generated research outputs or optimize convenient yet isolated performance metrics that provide coarse proxies for scientific insight. To address this gap, we introduce FIRE-Bench (Full-cycle Insight Rediscovery Evaluation), a benchmark that evaluates agents through the rediscovery of established findings from recent, high-impact machine learning research. Agents are given only a high-level research question extracted from a published, verified study and must autonomously explore ideas, design experiments, implement code, execute their plans, and derive conclusions supported by empirical evidence. We evaluate a range of state-of-the-art agents with frontier LLMs backbones like gpt-5 on FIRE-Bench. Our results show that full-cycle scientific research remains challenging for current agent systems: even the strongest agents achieve limited rediscovery success (<50 F1), exhibit high variance across runs, and display recurring failure modes in experimental design, execution, and evidence-based reasoning. FIRE-Bench provides a rigorous and diagnostic framework for measuring progress toward reliable agent-driven scientific discovery.

"Rebuilding" Statistics in the Age of AI: A Town Hall Discussion on Culture, Infrastructure, and Training

This article presents the full, original record of the 2024 Joint Statistical Meetings (JSM) town hall, "Statistics in the Age of AI," which convened leading statisticians to discuss how the field is evolving in response to advances in artificial intelligence, foundation models, large-scale empirical modeling, and data-intensive infrastructures. The town hall was structured around open panel discussion and extensive audience Q&A, with the aim of eliciting candid, experience-driven perspectives rather than formal presentations or prepared statements. This document preserves the extended exchanges among panelists and audience members, with minimal editorial intervention, and organizes the conversation around five recurring questions concerning disciplinary culture and practices, data curation and "data work," engagement with modern empirical modeling, training for large-scale AI applications, and partnerships with key AI stakeholders. By providing an archival record of this discussion, the preprint aims to support transparency, community reflection, and ongoing dialogue about the evolving role of statistics in the data- and AI-centric future.

Bridging Streaming Continual Learning via In-Context Large Tabular Models

In streaming scenarios, models must learn continuously, adapting to concept drifts without erasing previously acquired knowledge. However, existing research communities address these challenges in isolation. Continual Learning (CL) focuses on long-term retention and mitigating catastrophic forgetting, often without strict real-time constraints. Stream Learning (SL) emphasizes rapid, efficient adaptation to high-frequency data streams, but typically neglects forgetting. Recent efforts have tried to combine these paradigms, yet no clear algorithmic overlap exists. We argue that large in-context tabular models (LTMs) provide a natural bridge for Streaming Continual Learning (SCL). In our view, unbounded streams should be summarized on-the-fly into compact sketches that can be consumed by LTMs. This recovers the classical SL motivation of compressing massive streams with fixed-size guarantees, while simultaneously aligning with the experience-replay desiderata of CL. To clarify this bridge, we show how the SL and CL communities implicitly adopt a divide-to-conquer strategy to manage the tension between plasticity (performing well on the current distribution) and stability (retaining past knowledge), while also imposing a minimal complexity constraint that motivates diversification (avoiding redundancy in what is stored) and retrieval (re-prioritizing past information when needed). Within this perspective, we propose structuring SCL with LTMs around two core principles of data selection for in-context learning: (1) distribution matching, which balances plasticity and stability, and (2) distribution compression, which controls memory size through diversification and retrieval mechanisms.