LLaVA-OneVision-2: Towards Next-Generation Perceptual Intelligence

We introduce LLaVA-OneVision-2 (LLaVA-OV-2), the most capable vision-language model in the LLaVA-OneVision series to date, achieving superior performance across a broad range of multimodal benchmarks. The model builds on a native OneVision-Encoder and incorporates Windowed Attention for efficient local computation while maintaining native resolution. Its key advance is codec-stream tokenization: it treats compressed video as a continuous bit-cost stream, where bit-cost dynamics determine adaptive temporal groups, and motion-residual cues select salient spatial evidence into compact visual canvases. This allocation concentrates a limited token budget on event-bearing content, enabling more stable long-video token compression than fixed groups of pictures. A shared 3D RoPE further places codec canvases, sampled frames, and images in a unified spatiotemporal coordinate system. Furthermore, we build the LLaVA-OV-2 data and training stack around large-scale open supervision: approximately 8M re-captioned video samples for pretraining, a 4M-sample spatial corpus for fine-tuning. We also introduce JumpScore, a temporal-localization benchmark targeting fine-grained grounding in high-frequency, densely repeated motion, a regime underrepresented by existing video evaluations. A standout capability of LLaVA-OV-2 is its unified perception across video understanding, temporal grounding, spatial grounding, and manipulation-trace reasoning. On JumpScore, LLaVA-OneVision-2-8B reaches 74.9 JumpScore mAP, surpassing Qwen3-VL-8B (30.1) by +44.8 points; under matched visual-token budgets on the same benchmark, codec-stream inputs improve temporal grounding over frame sampling by +9.7 points. Across standard benchmarks, LLaVA-OneVision-2-8B further outperforms Qwen3-VL-8B by +4.3 average points on video tasks, +5.3 on spatial tasks, and +15.6 average J&F on tracking tasks.

DermAgent: A Self-Reflective Agentic System for Dermatological Image Analysis with Multi-Tool Reasoning and Traceable Decision-Making

Dermatological diagnosis requires integrating fine-grained visual perception with expert clinical knowledge. Although Multimodal Large Language Models (MLLMs) facilitate interactive medical image analysis, their application in dermatology is hindered by insufficient domain-specific grounding and hallucinations. To address these issues, we propose DermAgent, a collaborative multi-tool agent that orchestrates seven specialized vision and language modules within a Plan-Execute-Reflect framework. DermAgent delivers stepwise, traceable diagnostic reasoning through three core components. First, it employs complementary visual perception tools for comprehensive morphological description, dermoscopic concept annotation, and disease diagnosis. Second, to overcome the lack of domain prior, a dual-modality retrieval module anchors every prediction in external evidence by cross-referencing 413,210 diagnosed image cases and 3,199 clinical guideline chunks. To further mitigate hallucinations, a deterministic critic module conducts strict post-hoc auditing via confidence, coverage, and conflict gates, automatically detecting inter-source disagreements to trigger targeted self-correction. Extensive experiments on five dermatology benchmarks demonstrate that DermAgent consistently outperforms state-of-the-art MLLMs and medical agent baselines across zero-shot fine-grained disease diagnosis, concept annotation, and clinical captioning tasks, exceeding GPT-4o by 17.6% in skin disease diagnostic accuracy and 3.15% in captioning ROUGE-L. Our code is available at https://github.com/YizeezLiu/DermAgent.

Project Imaging-X: A Survey of 1000+ Open-Access Medical Imaging Datasets for Foundation Model Development

Foundation models have demonstrated remarkable success across diverse domains and tasks, primarily due to the thrive of large-scale, diverse, and high-quality datasets. However, in the field of medical imaging, the curation and assembling of such medical datasets are highly challenging due to the reliance on clinical expertise and strict ethical and privacy constraints, resulting in a scarcity of large-scale unified medical datasets and hindering the development of powerful medical foundation models. In this work, we present the largest survey to date of medical image datasets, covering over 1,000 open-access datasets with a systematic catalog of their modalities, tasks, anatomies, annotations, limitations, and potential for integration. Our analysis exposes a landscape that is modest in scale, fragmented across narrowly scoped tasks, and unevenly distributed across organs and modalities, which in turn limits the utility of existing medical image datasets for developing versatile and robust medical foundation models. To turn fragmentation into scale, we propose a metadata-driven fusion paradigm (MDFP) that integrates public datasets with shared modalities or tasks, thereby transforming multiple small data silos into larger, more coherent resources. Building on MDFP, we release an interactive discovery portal that enables end-to-end, automated medical image dataset integration, and compile all surveyed datasets into a unified, structured table that clearly summarizes their key characteristics and provides reference links, offering the community an accessible and comprehensive repository. By charting the current terrain and offering a principled path to dataset consolidation, our survey provides a practical roadmap for scaling medical imaging corpora, supporting faster data discovery, more principled dataset creation, and more capable medical foundation models.

Thinking in Uncertainty: Mitigating Hallucinations in MLRMs with Latent Entropy-Aware Decoding

Recent advancements in multimodal large reasoning models (MLRMs) have significantly improved performance in visual question answering. However, we observe that transition words (e.g., because, however, and wait) are closely associated with hallucinations and tend to exhibit high-entropy states. We argue that adequate contextual reasoning information can be directly extracted from the token probability distribution. Inspired by superposed representation theory, we propose leveraging latent superposed reasoning to integrate multiple candidate semantics and maintain latent reasoning trajectories. The hypothesis is that reliance on discrete textual inputs may drive the model toward sequential explicit reasoning, underutilizing dense contextual cues during high-entropy reasoning stages. Therefore, we propose constructing rich semantic representations from the token probability distributions to enhance in-context reasoning. With this goal, we present Latent Entropy-Aware Decoding (LEAD), an efficient plug-and-play decoding strategy that leverages semantic context to achieve reliable reasoning. The heart of our method lies in entropy-aware reasoning mode switching. The model employs probability-weighted continuous embeddings under high-entropy states and transitions back to discrete token embeddings as entropy decreases. Moreover, we propose a prior-guided visual anchor injection strategy that encourages the model to focus on visual information. Extensive experiments show that LEAD effectively mitigates hallucinations across various MLRMs on multiple benchmarks.

DeLo: Dual Decomposed Low-Rank Experts Collaboration for Continual Missing Modality Learning

Adapting Large Multimodal Models (LMMs) to real-world scenarios poses the dual challenges of learning from sequential data streams while handling frequent modality incompleteness, a task known as Continual Missing Modality Learning (CMML). However, existing works on CMML have predominantly relied on prompt tuning, a technique that struggles with this task due to cross-task interference between its learnable prompts in their shared embedding space. A naive application of Low-Rank Adaptation (LoRA) with modality-shared module will also suffer modality interference from competing gradients. To this end, we propose DeLo, the first framework to leverage a novel dual-decomposed low-rank expert architecture for CMML. Specifically, this architecture resolves modality interference through decomposed LoRA expert, dynamically composing LoRA update matrix with rank-one factors from disentangled modality-specific factor pools. Embedded within a task-partitioned framework that structurally prevents catastrophic forgetting, this expert system is supported by two key mechanisms: a Cross-Modal Guided Routing strategy to handle incomplete data and a Task-Key Memory for efficient, task-agnostic inference. Extensive experiments on established CMML benchmarks demonstrate that our method significantly outperforms state-of-the-art approaches. This highlights the value of a principled, architecturally-aware LoRA design for real-world multimodal challenges.

OneVision-Encoder: Codec-Aligned Sparsity as a Foundational Principle for Multimodal Intelligence

Hypothesis. Artificial general intelligence is, at its core, a compression problem. Effective compression demands resonance: deep learning scales best when its architecture aligns with the fundamental structure of the data. These are the fundamental principles. Yet, modern vision architectures have strayed from these truths: visual signals are highly redundant, while discriminative information, the surprise, is sparse. Current models process dense pixel grids uniformly, wasting vast compute on static background rather than focusing on the predictive residuals that define motion and meaning. We argue that to solve visual understanding, we must align our architectures with the information-theoretic principles of video, i.e., Codecs. Method. OneVision-Encoder encodes video by compressing predictive visual structure into semantic meaning. By adopting Codec Patchification, OV-Encoder abandons uniform computation to focus exclusively on the 3.1%-25% of regions rich in signal entropy. To unify spatial and temporal reasoning under irregular token layouts, OneVision-Encoder employs a shared 3D RoPE and is trained with a large-scale cluster discrimination objective over more than one million semantic concepts, jointly capturing object permanence and motion dynamics. Evidence. The results validate our core hypothesis: efficiency and accuracy are not a trade-off; they are positively correlated. When integrated into LLM, it consistently outperforms strong vision backbones such as Qwen3-ViT and SigLIP2 across 16 image, video, and document understanding benchmarks, despite using substantially fewer visual tokens and pretraining data. Notably, on video understanding tasks, OV-Encoder achieves an average improvement of 4.1% over Qwen3-ViT. Codec-aligned, patch-level sparsity is a foundational principle, enabling OV-Encoder as a scalable engine for next-generation visual generalists.

Hallucination Begins Where Saliency Drops

Recent studies have examined attention dynamics in large vision-language models (LVLMs) to detect hallucinations. However, existing approaches remain limited in reliably distinguishing hallucinated from factually grounded outputs, as they rely solely on forward-pass attention patterns and neglect gradient-based signals that reveal how token influence propagates through the network. To bridge this gap, we introduce LVLMs-Saliency, a gradient-aware diagnostic framework that quantifies the visual grounding strength of each output token by fusing attention weights with their input gradients. Our analysis uncovers a decisive pattern: hallucinations frequently arise when preceding output tokens exhibit low saliency toward the prediction of the next token, signaling a breakdown in contextual memory retention. Leveraging this insight, we propose a dual-mechanism inference-time framework to mitigate hallucinations: (1) Saliency-Guided Rejection Sampling (SGRS), which dynamically filters candidate tokens during autoregressive decoding by rejecting those whose saliency falls below a context-adaptive threshold, thereby preventing coherence-breaking tokens from entering the output sequence; and (2) Local Coherence Reinforcement (LocoRE), a lightweight, plug-and-play module that strengthens attention from the current token to its most recent predecessors, actively counteracting the contextual forgetting behavior identified by LVLMs-Saliency. Extensive experiments across multiple LVLMs demonstrate that our method significantly reduces hallucination rates while preserving fluency and task performance, offering a robust and interpretable solution for enhancing model reliability. Code is available at: https://github.com/zhangbaijin/LVLMs-Saliency

PsychEthicsBench: Evaluating Large Language Models Against Australian Mental Health Ethics

The increasing integration of large language models (LLMs) into mental health applications necessitates robust frameworks for evaluating professional safety alignment. Current evaluative approaches primarily rely on refusal-based safety signals, which offer limited insight into the nuanced behaviors required in clinical practice. In mental health, clinically inadequate refusals can be perceived as unempathetic and discourage help-seeking. To address this gap, we move beyond refusal-centric metrics and introduce \texttt{PsychEthicsBench}, the first principle-grounded benchmark based on Australian psychology and psychiatry guidelines, designed to evaluate LLMs' ethical knowledge and behavioral responses through multiple-choice and open-ended tasks with fine-grained ethicality annotations. Empirical results across 14 models reveal that refusal rates are poor indicators of ethical behavior, revealing a significant divergence between safety triggers and clinical appropriateness. Notably, we find that domain-specific fine-tuning can degrade ethical robustness, as several specialized models underperform their base backbones in ethical alignment. PsychEthicsBench provides a foundation for systematic, jurisdiction-aware evaluation of LLMs in mental health, encouraging more responsible development in this domain.

Phenome-Wide Multi-Omics Integration Uncovers Distinct Archetypes of Human Aging

Aging is a highly complex and heterogeneous process that progresses at different rates across individuals, making biological age (BA) a more accurate indicator of physiological decline than chronological age. While previous studies have built aging clocks using single-omics data, they often fail to capture the full molecular complexity of human aging. In this work, we leveraged the Human Phenotype Project, a large-scale cohort of 12,000 adults aged 30--70 years, with extensive longitudinal profiling that includes clinical, behavioral, environmental, and multi-omics datasets -- spanning transcriptomics, lipidomics, metabolomics, and the microbiome. By employing advanced machine learning frameworks capable of modeling nonlinear biological dynamics, we developed and rigorously validated a multi-omics aging clock that robustly predicts diverse health outcomes and future disease risk. Unsupervised clustering of the integrated molecular profiles from multi-omics uncovered distinct biological subtypes of aging, revealing striking heterogeneity in aging trajectories and pinpointing pathway-specific alterations associated with different aging patterns. These findings demonstrate the power of multi-omics integration to decode the molecular landscape of aging and lay the groundwork for personalized healthspan monitoring and precision strategies to prevent age-related diseases.

A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.