GenAI for Systems: Recurring Challenges and Design Principles from Software to Silicon

Generative AI is reshaping how computing systems are designed, optimized, and built, yet research remains fragmented across software, architecture, and chip design communities. This paper takes a cross-stack perspective, examining how generative models are being applied from code generation and distributed runtimes through hardware design space exploration to RTL synthesis, physical layout, and verification. Rather than reviewing each layer in isolation, we analyze how the same structural difficulties and effective responses recur across the stack. Our central finding is one of convergence. Despite the diversity of domains and tools, the field keeps encountering five recurring challenges (the feedback loop crisis, the tacit knowledge problem, trust and validation, co-design across boundaries, and the shift from determinism to dynamism) and keeps arriving at five design principles that independently emerge as effective responses (embracing hybrid approaches, designing for continuous feedback, separating concerns by role, matching methods to problem structure, and building on decades of systems knowledge). We organize these into a challenge--principle map that serves as a diagnostic and design aid, showing which principles have proven effective for which challenges across layers. Through concrete cross-stack examples, we show how systems navigate this map as they mature, and argue that the field needs shared engineering methodology, including common vocabularies, cross-layer benchmarks, and systematic design practices, so that progress compounds across communities rather than being rediscovered in each one. Our analysis covers more than 275 papers spanning eleven application areas across three layers of the computing stack, and distills open research questions that become visible only from a cross-layer vantage point.

VLM-UQBench: A Benchmark for Modality-Specific and Cross-Modality Uncertainties in Vision Language Models

Uncertainty quantification (UQ) is vital for ensuring that vision-language models (VLMs) behave safely and reliably. A central challenge is to localize uncertainty to its source, determining whether it arises from the image, the text, or misalignment between the two. We introduce VLM-UQBench, a benchmark for modality-specific and cross-modal data uncertainty in VLMs, It consists of 600 real-world samples drawn from the VizWiz dataset, curated into clean, image-, text-, and cross-modal uncertainty subsets, and a scalable perturbation pipeline with 8 visual, 5 textual, and 3 cross-modal perturbations. We further propose two simple metrics that quantify the sensitivity of UQ scores to these perturbations and their correlation with hallucinations, and use them to evaluate a range of UQ methods across four VLMs and three datasets. Empirically, we find that: (i) existing UQ methods exhibit strong modality-specific specialization and substantial dependence on the underlying VLM, (ii) modality-specific uncertainty frequently co-occurs with hallucinations while current UQ scores provide only weak and inconsistent risk signals, and (iii) although UQ methods can rival reasoning-based chain-of-thought baselines on overt, group-level ambiguity, they largely fail to detect the subtle, instance-level ambiguity introduced by our perturbation pipeline. These results highlight a significant gap between current UQ practices and the fine-grained, modality-aware uncertainty required for reliable VLM deployment.

Kirin: Improving ANN efficiency with SNN Hybridization

Artificial neural networks (ANNs), particularly large language models (LLMs), demonstrate powerful inference capabilities but consume substantial energy. Conversely, spiking neural networks (SNNs) exhibit exceptional energy efficiency due to their binary and event-driven characteristics, thus motivating the study of ANN-to-SNN conversion. In this process, quantization plays a pivotal role, mapping LLMs' floating-point parameters to discrete SNN parameters via the temporal dimension of the time window. However, several challenges remain in the conversion process: (i) converting high bit-width quantization values into binary spikes requires longer time windows, increasing system latency; and (ii) the inherent trade-off between the information loss of single-spike schemes and the energy costs of multi-spike ones in SNN. To address these challenges, we propose Kirin, a integer and spike hybrid based SNN to achieve accuracy lossless ANN-to-SNN conversion with time and energy efficiency. Specifically, we first propose a Spike Matrix Hybridization strategy that encoding low bit-width parameters that leading to small time window size into binary spikes while preserving the rest in integer format, thereby reducing the overall latency of SNN execution. Second, we introduce a silence threshold mechanism to regulate the timing of single-spike firing, ensuring the output is mathematically equivalent to the LLM's output and preserves accuracy. Experimental results demonstrate that Kirin, under a W4A4\&8 quantization setting, achieves near-FP16 accuracy while reducing energy consumption by up to 84.66\% and shortening time steps by 93.75\%.

SPICE: Submodular Penalized Information-Conflict Selection for Efficient Large Language Model Training

Information-based data selection for instruction tuning is compelling: maximizing the log-determinant of the Fisher information yields a monotone submodular objective, enabling greedy algorithms to achieve a $(1-1/e)$ approximation under a cardinality budget. In practice, however, we identify alleviating gradient conflicts, misalignment between per-sample gradients, is a key factor that slows down the decay of marginal log-determinant information gains, thereby preventing significant loss of information. We formalize this via an $\varepsilon$-decomposition that quantifies the deviation from ideal submodularity as a function of conflict statistics, yielding data-dependent approximation factors that tighten as conflicts diminish. Guided by this analysis, we propose SPICE, a conflict-aware selector that maximizes information while penalizing misalignment, and that supports early stopping and proxy models for efficiency. Empirically, SPICE selects subsets with higher log-determinant information than original criteria, and these informational gains translate into performance improvements: across 8 benchmarks with LLaMA2-7B and Qwen2-7B, SPICE uses only 10% of the data, yet matches or exceeds 6 methods including full-data tuning. This achieves performance improvements with substantially lower training cost.

Kling-Omni Technical Report

We present Kling-Omni, a generalist generative framework designed to synthesize high-fidelity videos directly from multimodal visual language inputs. Adopting an end-to-end perspective, Kling-Omni bridges the functional separation among diverse video generation, editing, and intelligent reasoning tasks, integrating them into a holistic system. Unlike disjointed pipeline approaches, Kling-Omni supports a diverse range of user inputs, including text instructions, reference images, and video contexts, processing them into a unified multimodal representation to deliver cinematic-quality and highly-intelligent video content creation. To support these capabilities, we constructed a comprehensive data system that serves as the foundation for multimodal video creation. The framework is further empowered by efficient large-scale pre-training strategies and infrastructure optimizations for inference. Comprehensive evaluations reveal that Kling-Omni demonstrates exceptional capabilities in in-context generation, reasoning-based editing, and multimodal instruction following. Moving beyond a content creation tool, we believe Kling-Omni is a pivotal advancement toward multimodal world simulators capable of perceiving, reasoning, generating and interacting with the dynamic and complex worlds.

Slm-mux: Orchestrating small language models for reasoning

With the rapid development of language models, the number of small language models (SLMs) has grown significantly. Although they do not achieve state-of-the-art accuracy, they are more efficient and often excel at specific tasks. This raises a natural question: can multiple SLMs be orchestrated into a system where each contributes effectively, achieving higher accuracy than any individual model? Existing orchestration methods have primarily targeted frontier models (e.g., GPT-4) and perform suboptimally when applied to SLMs. To address this gap, we propose a three-stage approach for orchestrating SLMs. First, we introduce SLM-MUX, a multi-model architecture that effectively coordinates multiple SLMs. Building on this, we develop two optimization strategies: (i) a model selection search that identifies the most complementary SLMs from a given pool, and (ii) test-time scaling tailored to SLM-MUX. Our approach delivers strong results: Compared to existing orchestration methods, our approach achieves up to 13.4% improvement on MATH, 8.8% on GPQA, and 7.0% on GSM8K. With just two SLMS, SLM-MUX outperforms Qwen 2.5 72B on GPQA and GSM8K, and matches its performance on MATH. We further provide theoretical analyses to substantiate the advantages of our method. In summary, we demonstrate that SLMs can be effectively orchestrated into more accurate and efficient systems through the proposed approach.

Seeing from Another Perspective: Evaluating Multi-View Understanding in MLLMs

Multi-view understanding, the ability to reconcile visual information across diverse viewpoints for effective navigation, manipulation, and 3D scene comprehension, is a fundamental challenge in Multi-Modal Large Language Models (MLLMs) to be used as embodied agents. While recent MLLMs have shown impressive advances in high-level reasoning and planning, they frequently fall short when confronted with multi-view geometric consistency and cross-view correspondence. To comprehensively evaluate the challenges of MLLMs in multi-view scene reasoning, we propose All-Angles Bench, a benchmark of over 2,100 human carefully annotated multi-view question-answer pairs across 90 diverse real-world scenes. Our six tasks (counting, attribute identification, relative distance, relative direction, object manipulation, and camera pose estimation) specifically test model's geometric correspondence and the capacity to align information consistently across views. Our extensive experiments, benchmark on 27 representative MLLMs including Gemini-2.0-Flash, Claude-3.7-Sonnet, and GPT-4o against human evaluators reveals a substantial performance gap, indicating that current MLLMs remain far from human-level proficiency. Through in-depth analysis, we show that MLLMs are particularly underperforming under two aspects: (1) cross-view correspondence for partially occluded views and (2) establishing the coarse camera poses. These findings highlight the necessity of domain-specific refinements or modules that embed stronger multi-view awareness. We believe that our All-Angles Bench offers valuable insights and contribute to bridging the gap between MLLMs and human-level multi-view understanding. The project and benchmark are publicly available at https://danielchyeh.github.io/All-Angles-Bench/.

Reward-Guided Controlled Generation for Inference-Time Alignment in Diffusion Models: Tutorial and Review

This tutorial provides an in-depth guide on inference-time guidance and alignment methods for optimizing downstream reward functions in diffusion models. While diffusion models are renowned for their generative modeling capabilities, practical applications in fields such as biology often require sample generation that maximizes specific metrics (e.g., stability, affinity in proteins, closeness to target structures). In these scenarios, diffusion models can be adapted not only to generate realistic samples but also to explicitly maximize desired measures at inference time without fine-tuning. This tutorial explores the foundational aspects of such inference-time algorithms. We review these methods from a unified perspective, demonstrating that current techniques -- such as Sequential Monte Carlo (SMC)-based guidance, value-based sampling, and classifier guidance -- aim to approximate soft optimal denoising processes (a.k.a. policies in RL) that combine pre-trained denoising processes with value functions serving as look-ahead functions that predict from intermediate states to terminal rewards. Within this framework, we present several novel algorithms not yet covered in the literature. Furthermore, we discuss (1) fine-tuning methods combined with inference-time techniques, (2) inference-time algorithms based on search algorithms such as Monte Carlo tree search, which have received limited attention in current research, and (3) connections between inference-time algorithms in language models and diffusion models. The code of this tutorial on protein design is available at https://github.com/masa-ue/AlignInversePro

Automated Generation of Challenging Multiple-Choice Questions for Vision Language Model Evaluation

The rapid development of vision language models (VLMs) demands rigorous and reliable evaluation. However, current visual question answering (VQA) benchmarks often depend on open-ended questions, making accurate evaluation difficult due to the variability in natural language responses. To address this, we introduce AutoConverter, an agentic framework that automatically converts these open-ended questions into multiple-choice format, enabling objective evaluation while reducing the costly question creation process. Our experiments demonstrate that AutoConverter can generate correct and challenging multiple-choice questions, with VLMs demonstrating consistently similar or lower accuracy on these questions compared to human-created ones. Using AutoConverter, we construct VMCBench, a benchmark created by transforming 20 existing VQA datasets into a unified multiple-choice format, totaling 9,018 questions. We comprehensively evaluate 33 state-of-the-art VLMs on VMCBench, setting a new standard for scalable, consistent, and reproducible VLM evaluation.

Semantic Consistency-Based Uncertainty Quantification for Factuality in Radiology Report Generation

Radiology report generation (RRG) has shown great potential in assisting radiologists by automating the labor-intensive task of report writing. While recent advancements have improved the quality and coherence of generated reports, ensuring their factual correctness remains a critical challenge. Although generative medical Vision Large Language Models (VLLMs) have been proposed to address this issue, these models are prone to hallucinations and can produce inaccurate diagnostic information. To address these concerns, we introduce a novel Semantic Consistency-Based Uncertainty Quantification framework that provides both report-level and sentence-level uncertainties. Unlike existing approaches, our method does not require modifications to the underlying model or access to its inner state, such as output token logits, thus serving as a plug-and-play module that can be seamlessly integrated with state-of-the-art models. Extensive experiments demonstrate the efficacy of our method in detecting hallucinations and enhancing the factual accuracy of automatically generated radiology reports. By abstaining from high-uncertainty reports, our approach improves factuality scores by $10$%, achieved by rejecting $20$% of reports using the Radialog model on the MIMIC-CXR dataset. Furthermore, sentence-level uncertainty flags the lowest-precision sentence in each report with an $82.9$% success rate.