NaviRAG: Towards Active Knowledge Navigation for Retrieval-Augmented Generation

Retrieval-augmented generation (RAG) typically relies on a flat retrieval paradigm that maps queries directly to static, isolated text segments. This approach struggles with more complex tasks that require the conditional retrieval and dynamic synthesis of information across different levels of granularity (e.g., from broad concepts to specific evidence). To bridge this gap, we introduce NaviRAG, a novel framework that shifts from passive segment retrieval to active knowledge navigation. NaviRAG first structures the knowledge documents into a hierarchical form, preserving semantic relationships from coarse-grained topics to fine-grained details. Leveraging this reorganized knowledge records, a large language model (LLM) agent actively navigates the records, iteratively identifying information gaps and retrieving relevant content from the most appropriate granularity level. Extensive experiments on long-document QA benchmarks show that NaviRAG consistently improves both retrieval recall and end-to-end answer performance over conventional RAG baselines. Ablation studies confirm performance gains stem from our method's capacity for multi-granular evidence localization and dynamic retrieval planning. We further discuss efficiency, applicable scenario, and future directions of our method, hoping to make RAG systems more intelligent and autonomous.

Perturb-and-Restore: Simulation-driven Structural Augmentation Framework for Imbalance Chromosomal Anomaly Detection

Detecting structural chromosomal abnormalities is crucial for accurate diagnosis and management of genetic disorders. However, collecting sufficient structural abnormality data is extremely challenging and costly in clinical practice, and not all abnormal types can be readily collected. As a result, deep learning approaches face significant performance degradation due to the severe imbalance and scarcity of abnormal chromosome data. To address this challenge, we propose a Perturb-and-Restore (P&R), a simulation-driven structural augmentation framework that effectively alleviates data imbalance in chromosome anomaly detection. The P&R framework comprises two key components: (1) Structure Perturbation and Restoration Simulation, which generates synthetic abnormal chromosomes by perturbing chromosomal banding patterns of normal chromosomes followed by a restoration diffusion network that reconstructs continuous chromosome content and edges, thus eliminating reliance on rare abnormal samples; and (2) Energy-guided Adaptive Sampling, an energy score-based online selection strategy that dynamically prioritizes high-quality synthetic samples by referencing the energy distribution of real samples. To evaluate our method, we construct a comprehensive structural anomaly dataset consisting of over 260,000 chromosome images, including 4,242 abnormal samples spanning 24 categories. Experimental results demonstrate that the P&R framework achieves state-of-the-art (SOTA) performance, surpassing existing methods with an average improvement of 8.92% in sensitivity, 8.89% in precision, and 13.79% in F1-score across all categories.

Self-Supervised Learning for Knee Osteoarthritis: Diagnostic Limitations and Prognostic Value of Uncurated Hospital Data

This study assesses whether self-supervised learning (SSL) improves knee osteoarthritis (OA) modeling for diagnosis and prognosis relative to ImageNet-pretrained initialization. We compared (i) image-only SSL pretrained on knee radiographs from the OAI, MOST, and NYU cohorts, and (ii) multimodal image-text SSL pretrained on uncurated hospital knee radiographs paired with radiologist impressions. For diagnostic Kellgren-Lawrence (KL) grade prediction, SSL offered mixed results. While image-only SSL improved accuracy during linear probing (frozen encoder), it did not outperform ImageNet pretraining during full fine-tuning. Similarly, multimodal SSL failed to improve grading performance. We attribute this to severe bias in the uncurated hospital pretraining corpus (93% estimated KL grade 3), which limited alignment with the balanced diagnostic task. In contrast, this same multimodal initialization significantly improved prognostic modeling. It outperformed ImageNet baselines in predicting 4-year structural incidence and progression, including on external validation (MOST AUROC: 0.701 vs. 0.599 at 10% labeled data). Overall, while uncurated hospital image-text data may be ineffective for learning diagnosis due to severity bias, it provides a strong signal for prognostic modeling when the downstream task aligns with pretraining data distribution

From Ideal to Real: Stable Video Object Removal under Imperfect Conditions

Removing objects from videos remains difficult in the presence of real-world imperfections such as shadows, abrupt motion, and defective masks. Existing diffusion-based video inpainting models often struggle to maintain temporal stability and visual consistency under these challenges. We propose Stable Video Object Removal (SVOR), a robust framework that achieves shadow-free, flicker-free, and mask-defect-tolerant removal through three key designs: (1) Mask Union for Stable Erasure (MUSE), a windowed union strategy applied during temporal mask downsampling to preserve all target regions observed within each window, effectively handling abrupt motion and reducing missed removals; (2) Denoising-Aware Segmentation (DA-Seg), a lightweight segmentation head on a decoupled side branch equipped with Denoising-Aware AdaLN and trained with mask degradation to provide an internal diffusion-aware localization prior without affecting content generation; and (3) Curriculum Two-Stage Training: where Stage I performs self-supervised pretraining on unpaired real-background videos with online random masks to learn realistic background and temporal priors, and Stage II refines on synthetic pairs using mask degradation and side-effect-weighted losses, jointly removing objects and their associated shadows/reflections while improving cross-domain robustness. Extensive experiments show that SVOR attains new state-of-the-art results across multiple datasets and degraded-mask benchmarks, advancing video object removal from ideal settings toward real-world applications.

FastCode: Fast and Cost-Efficient Code Understanding and Reasoning

Repository-scale code reasoning is a cornerstone of modern AI-assisted software engineering, enabling Large Language Models (LLMs) to handle complex workflows from program comprehension to complex debugging. However, balancing accuracy with context cost remains a significant bottleneck, as existing agentic approaches often waste computational resources through inefficient, iterative full-text exploration. To address this, we introduce FastCode, a framework that decouples repository exploration from content consumption. FastCode utilizes a structural scouting mechanism to navigate a lightweight semantic-structural map of the codebase, allowing the system to trace dependencies and pinpoint relevant targets without the overhead of full-text ingestion. By leveraging structure-aware navigation tools regulated by a cost-aware policy, the framework constructs high-value contexts in a single, optimized step. Extensive evaluations on the SWE-QA, LongCodeQA, LOC-BENCH, and GitTaskBench benchmarks demonstrate that FastCode consistently outperforms state-of-the-art baselines in reasoning accuracy while significantly reducing token consumption, validating the efficiency of scouting-first strategies for large-scale code reasoning. Source code is available at https://github.com/HKUDS/FastCode.

UniWhisper: Efficient Continual Multi-task Training for Robust Universal Audio Representation

A universal audio representation should capture fine-grained speech cues and high-level semantics for environmental sounds and music in a single encoder. Existing encoders often excel in one domain but degrade in others. We propose UniWhisper, an efficient continual multi-task training framework that casts heterogeneous audio tasks into a unified instruction and answer format. This enables standard next-token training without task-specific heads and losses. We train it on 38k hours of public audio and assess the encoder using shallow MLP probes and k-nearest neighbors (kNN) on 20 tasks spanning speech, environmental sound, and music. UniWhisper reaches normalized weighted averages of 0.81 with MLP probes and 0.61 with kNN, compared to 0.64 and 0.46 for Whisper, while retaining strong speech performance.

Grounding LLMs in Scientific Discovery via Embodied Actions

Large Language Models (LLMs) have shown significant potential in scientific discovery but struggle to bridge the gap between theoretical reasoning and verifiable physical simulation. Existing solutions operate in a passive "execute-then-response" loop and thus lacks runtime perception, obscuring agents to transient anomalies (e.g., numerical instability or diverging oscillations). To address this limitation, we propose EmbodiedAct, a framework that transforms established scientific software into active embodied agents by grounding LLMs in embodied actions with a tight perception-execution loop. We instantiate EmbodiedAct within MATLAB and evaluate it on complex engineering design and scientific modeling tasks. Extensive experiments show that EmbodiedAct significantly outperforms existing baselines, achieving SOTA performance by ensuring satisfactory reliability and stability in long-horizon simulations and enhanced accuracy in scientific modeling.

Constructing Industrial-Scale Optimization Modeling Benchmark

Optimization modeling underpins decision-making in logistics, manufacturing, energy, and finance, yet translating natural-language requirements into correct optimization formulations and solver-executable code remains labor-intensive. Although large language models (LLMs) have been explored for this task, evaluation is still dominated by toy-sized or synthetic benchmarks, masking the difficulty of industrial problems with $10^{3}$--$10^{6}$ (or more) variables and constraints. A key bottleneck is the lack of benchmarks that align natural-language specifications with reference formulations/solver code grounded in real optimization models. To fill in this gap, we introduce MIPLIB-NL, built via a structure-aware reverse construction methodology from real mixed-integer linear programs in MIPLIB~2017. Our pipeline (i) recovers compact, reusable model structure from flat solver formulations, (ii) reverse-generates natural-language specifications explicitly tied to this recovered structure under a unified model--data separation format, and (iii) performs iterative semantic validation through expert review and human--LLM interaction with independent reconstruction checks. This yields 223 one-to-one reconstructions that preserve the mathematical content of the original instances while enabling realistic natural-language-to-optimization evaluation. Experiments show substantial performance degradation on MIPLIB-NL for systems that perform strongly on existing benchmarks, exposing failure modes invisible at toy scale.

DrugR: Optimizing Molecular Drugs through LLM-based Explicit Reasoning

Molecule generation and optimization is a fundamental task in chemical domain. The rapid development of intelligent tools, especially large language models (LLMs) with powerful knowledge reserves and interactive capabilities, has provided new paradigms for it. Nevertheless, the intrinsic challenge for LLMs lies in the complex implicit relationship between molecular structure and pharmacological properties and the lack of corresponding labeled data. To bridge this gap, we propose DrugR, an LLM-based method that introduces explicit, step-by-step pharmacological reasoning into the optimization process. Our approach integrates domain-specific continual pretraining, supervised fine-tuning via reverse data engineering, and self-balanced multi-granular reinforcement learning. This framework enables DrugR to effectively improve key ADMET properties while preserving the original molecule's core efficacy. Experimental results demonstrate that DrugR achieves comprehensive enhancement across multiple properties without compromising structural similarity or target binding affinity. Importantly, its explicit reasoning process provides clear, interpretable rationales for each optimization step, yielding actionable design insights and advancing toward automated, knowledge-driven scientific discovery. Our code and model checkpoints are open-sourced to foster future research.

Prompt Reinjection: Alleviating Prompt Forgetting in Multimodal Diffusion Transformers

Multimodal Diffusion Transformers (MMDiTs) for text-to-image generation maintain separate text and image branches, with bidirectional information flow between text tokens and visual latents throughout denoising. In this setting, we observe a prompt forgetting phenomenon: the semantics of the prompt representation in the text branch is progressively forgotten as depth increases. We further verify this effect on three representative MMDiTs--SD3, SD3.5, and FLUX.1 by probing linguistic attributes of the representations over the layers in the text branch. Motivated by these findings, we introduce a training-free approach, prompt reinjection, which reinjects prompt representations from early layers into later layers to alleviate this forgetting. Experiments on GenEval, DPG, and T2I-CompBench++ show consistent gains in instruction-following capability, along with improvements on metrics capturing preference, aesthetics, and overall text--image generation quality.