Abstract:AI-based Visually Impaired Assistance (VIA) remains challenging, largely due to the high cost of human evaluation. The VLM-as-a-Judge paradigm may offer a promising alternative, although it has mostly been studied in general domains. We therefore ask whether such judges can be trusted for VIA tasks. To investigate this question, we introduce VIABLE (Visually Impaired Assistance Benchmark for VLM-as-a-Judge Evaluation), the first benchmark for VLM-as-a-Judge evaluation in VIA. VIABLE contains over 300K judgment samples across three scenarios and introduces an Effectiveness--Impartiality--Stability framework with a 12-mode failure taxonomy. Based on VIABLE, our systematic study of seven judges across different model scales shows that existing models are largely unreliable across all evaluation axes. The strongest judge, GPT-5.4, achieves only 52.6% single-failure diagnostic accuracy, yet exhibits the highest self-preference rate at 94.2%; while open-source judges are strongly biased and adversarially fragile. To address these issues, we propose VIA-Judge-Agent, a model-agnostic inference-time harness that augments judges with visual evidence extraction and a taxonomy-guided workflow. It enables positive improvements in diagnostic accuracy and downstream VIA responses more preferred by BLV users. Data and code are available at: https://github.com/YiyiyiZhao/VIABLE
Abstract:We introduce ERNIE-Image, an open-source text-to-image generation model built upon an 8B single-stream DiT architecture. ERNIE-Image aims to bridge the gap between current open-source models and leading closed-source systems through more effective mining of large-scale pre-training data and improved supervision quality throughout training. During pre-training, we adopt a bottom-up data construction pipeline that combines fine-grained image categorization, rich caption annotation, aesthetic assessment, and hierarchical sampling. This strategy reduces data noise while preserving long-tail concepts and detailed real-world knowledge, providing a stronger foundation for complex generation tasks. In the post-training stage, we use a top-down data construction pipeline for high-demand scenarios, diversify prompt annotations to better match real user inputs, and apply a stabilized DPO strategy to align the model with human aesthetic preferences. We further train ERNIE-Image-Turbo for efficient 8-NFE generation and propose MT-DMD to mitigate capability drift during distillation. To make the model easier to use in practical scenarios, we equip it with a lightweight Prompt Enhancer that expands concise user intents into structured visual descriptions. In addition, we develop ERNIE-Image-Aes, an industrial-grade aesthetic model, together with ERNIE-Image-Aes-1K, a human-annotated benchmark for realistic aesthetic evaluation. Extensive qualitative and quantitative experiments show that ERNIE-Image achieves leading performance among open-source models and approaches top-tier commercial models in instruction following, text rendering, and aesthetic quality. We release the trained models and aesthetic resources to facilitate further academic research and technical progress in the AIGC community.
Abstract:Despite years of methodological progress, how far AI has come in liver fibrosis staging has never been systematically evaluated under the heterogeneous, multi-center conditions that define clinical practice. To address this gap, we introduce LiFS, a large-scale dataset and benchmark derived from the MICCAI 2025 CARE-Liver challenge, comprising 610 patients across multiple centers and scanners with multi-sequence MRI. To the best of our knowledge, LiFS is the first benchmark providing complete gadoxetic acid-enhanced sequences with histopathology-confirmed annotations from diverse real-world scanners. Through systematic evaluation of 9 independently developed methods selected from 96 registered teams against in-cohort radiologist reference results, our findings address how far current AI has progressed toward clinical-level liver fibrosis staging from three complementary perspectives. First, against radiologists, the best AI methods were broadly comparable to the senior radiologist and significantly exceeded the junior radiologist in selected settings, while median AI performance generally approached junior-radiologist levels. Second, from a data perspective, cross-center heterogeneity, label imbalance, and contrast-enhanced sequence variability emerge as the dominant challenges for AI methods. Third, from a technical perspective, methodological design choices, including spatial registration, input dimensionality, multi-modal fusion strategy, and backbone architecture, appear to modulate cross-center robustness, although no single choice alone closes the gap. Overall, LiFS provides a rigorous real-world benchmark for positioning the current state of AI in liver fibrosis staging and for enabling future research on the key challenges that limit clinically reliable deployment.
Abstract:Text-driven motion editing and intra-structural retargeting, where source and target share topology but may differ in bone lengths, are traditionally handled by fragmented pipelines with incompatible inputs and representations: editing relies on specialized generative steering, while retargeting is deferred to geometric post-processing. We present a unifying perspective where both tasks are cast as instances of conditional transport within a single generative framework. By leveraging recent advances in flow matching, we demonstrate that editing and retargeting are fundamentally the same generative task, distinguished only by which conditioning signal, semantic or structural, is modulated during inference. We implement this vision via a rectified-flow motion model jointly conditioned on text prompts and target skeletal structures. Our architecture extends a DiT-style transformer with per-joint tokenization and explicit joint self-attention to strictly enforce kinematic dependencies, while a multi-condition classifier-free guidance strategy balances text adherence with skeletal conformity. Experiments on SnapMoGen and a multi-character Mixamo subset show that a single trained model supports text-to-motion generation, zero-shot editing, and zero-shot intra-structural retargeting. This unified approach simplifies deployment and improves structural consistency compared to task-specific baselines.
Abstract:In scientific and engineering domains, modeling high-dimensional complex systems governed by partial differential equations (PDEs) remains challenging in terms of physical consistency and numerical stability. However, existing approaches, such as physics-informed neural networks (PINNs), typically rely on known physical fields or coefficients and enforce physical constraints via external loss functions, which can lead to training instability and make it difficult to handle high-dimensional or unobservable scenarios. To this end, we propose PhysFormer, a generative modeling framework that is self-consistent at both the data and physical levels. PhysFormer leverages a low-dimensional, physically interpretable latent space to learn key physical quantities directly from data without requiring known high-dimensional physical field parameters, and embeds the physical process of radiative flux generation within the network to ensure the physical consistency of the generated spectra. In high-dimensional, degenerate inversion tasks, PhysFormer constrains generation within physical limits and enhances spectral fidelity and inversion stability under varying signal-to-noise ratios (SNRs). More broadly, this approach shifts the physical processes from external loss functions into the generative mechanism itself, providing a physically consistent generative modeling paradigm for complex systems involving unknown or unobservable physical quantities.
Abstract:In biomedical engineering, artificial intelligence has become a pivotal tool for enhancing medical diagnostics, particularly in medical image classification tasks such as detecting pneumonia from chest X-rays and breast cancer screening. However, real-world medical datasets frequently exhibit severe class imbalance, where positive samples substantially outnumber negative samples, leading to biased models with low recall rates for minority classes. This imbalance not only compromises diagnostic accuracy but also poses clinical misdiagnosis risks. To address this challenge, we propose SDA-QEC (Simplified Diffusion Augmentation with Quantum-Enhanced Classification), an innovative framework that integrates simplified diffusion-based data augmentation with quantum-enhanced feature discrimination. Our approach employs a lightweight diffusion augmentor to generate high-quality synthetic samples for minority classes, rebalancing the training distribution. Subsequently, a quantum feature layer embedded within MobileNetV2 architecture enhances the model's discriminative capability through high-dimensional feature mapping in Hilbert space. Comprehensive experiments on coronary angiography image classification demonstrate that SDA-QEC achieves 98.33% accuracy, 98.78% AUC, and 98.33% F1-score, significantly outperforming classical baselines including ResNet18, MobileNetV2, DenseNet121, and VGG16. Notably, our framework simultaneously attains 98.33% sensitivity and 98.33% specificity, achieving a balanced performance critical for clinical deployment. The proposed method validates the feasibility of integrating generative augmentation with quantum-enhanced modeling in real-world medical imaging tasks, offering a novel research pathway for developing highly reliable medical AI systems in small-sample, highly imbalanced, and high-risk diagnostic scenarios.
Abstract:Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting clinical generalizability. To address this challenge, we propose a lightweight domain generalization framework with quantum-enhanced collaborative learning, enabling robust generalization to unseen target domains without relying on real multi-center labeled data. Specifically, a MobileNetV2-based domain-invariant encoder is constructed and optimized through three key components: (1) multi-domain imaging shift simulation using brightness, contrast, sharpening, and noise perturbations to emulate heterogeneous acquisition conditions; (2) domain-adversarial training with gradient reversal to suppress domain-discriminative features; and (3) a lightweight quantum feature enhancement layer that applies parameterized quantum circuits for nonlinear feature mapping and entanglement modeling. In addition, a test-time adaptation strategy is employed during inference to further alleviate distribution shifts. Experiments on simulated multi-center medical imaging datasets demonstrate that the proposed method significantly outperforms baseline models without domain generalization or quantum enhancement on unseen domains, achieving reduced domain-specific performance variance and improved AUC and sensitivity. These results highlight the clinical potential of quantum-enhanced domain generalization under constrained computational resources and provide a feasible paradigm for hybrid quantum--classical medical imaging systems.
Abstract:Intelligent medical image analysis is essential for clinical decision support but is often limited by scarce annotations, constrained computational resources, and suboptimal model generalization. To address these challenges, we propose a lightweight medical image classification framework that integrates self-supervised contrastive learning with quantum-enhanced feature modeling. MobileNetV2 is employed as a compact backbone and pretrained using a SimCLR-style self-supervised paradigm on unlabeled images. A lightweight parameterized quantum circuit (PQC) is embedded as a quantum feature enhancement module, forming a hybrid classical-quantum architecture, which is subsequently fine-tuned on limited labeled data. Experimental results demonstrate that, with only approximately 2-3 million parameters and low computational cost, the proposed method consistently outperforms classical baselines without self-supervised learning or quantum enhancement in terms of Accuracy, AUC, and F1-score. Feature visualization further indicates improved discriminability and representation stability. Overall, this work provides a practical and forward-looking solution for high-performance medical artificial intelligence under resource-constrained settings.
Abstract:Background: Coronary angiography (CAG) is a cornerstone imaging modality for assessing coronary artery disease and guiding interventional treatment decisions. However, in real-world clinical settings, angiographic images are often characterized by complex lesion morphology, severe class imbalance, label uncertainty, and limited computational resources, posing substantial challenges to conventional deep learning approaches in terms of robustness and generalization.Methods: The proposed framework is built upon a pretrained convolutional neural network to construct a lightweight hybrid neural representation. A selective neural plasticity training strategy is introduced to enable efficient parameter adaptation. Furthermore, a brain-inspired attention-modulated loss function, combining Focal Loss with label smoothing, is employed to enhance sensitivity to hard samples and uncertain annotations. Class-imbalance-aware sampling and cosine annealing with warm restarts are adopted to mimic rhythmic regulation and attention allocation mechanisms observed in biological neural systems.Results: Experimental results demonstrate that the proposed lightweight brain-inspired model achieves strong and stable performance in binary coronary angiography classification, yielding competitive accuracy, recall, F1-score, and AUC metrics while maintaining high computational efficiency.Conclusion: This study validates the effectiveness of brain-inspired learning mechanisms in lightweight medical image analysis and provides a biologically plausible and deployable solution for intelligent clinical decision support under limited computational resources.
Abstract:Vision-Language Models (VLMs) have made significant progress in explicit instruction-based navigation; however, their ability to interpret implicit human needs (e.g., "I am thirsty") in dynamic urban environments remains underexplored. This paper introduces CitySeeker, a novel benchmark designed to assess VLMs' spatial reasoning and decision-making capabilities for exploring embodied urban navigation to address implicit needs. CitySeeker includes 6,440 trajectories across 8 cities, capturing diverse visual characteristics and implicit needs in 7 goal-driven scenarios. Extensive experiments reveal that even top-performing models (e.g., Qwen2.5-VL-32B-Instruct) achieve only 21.1% task completion. We find key bottlenecks in error accumulation in long-horizon reasoning, inadequate spatial cognition, and deficient experiential recall. To further analyze them, we investigate a series of exploratory strategies-Backtracking Mechanisms, Enriching Spatial Cognition, and Memory-Based Retrieval (BCR), inspired by human cognitive mapping's emphasis on iterative observation-reasoning cycles and adaptive path optimization. Our analysis provides actionable insights for developing VLMs with robust spatial intelligence required for tackling "last-mile" navigation challenges.