OCELOT 2023: Cell Detection from Cell-Tissue Interaction Challenge

Pathologists routinely alternate between different magnifications when examining Whole-Slide Images, allowing them to evaluate both broad tissue morphology and intricate cellular details to form comprehensive diagnoses. However, existing deep learning-based cell detection models struggle to replicate these behaviors and learn the interdependent semantics between structures at different magnifications. A key barrier in the field is the lack of datasets with multi-scale overlapping cell and tissue annotations. The OCELOT 2023 challenge was initiated to gather insights from the community to validate the hypothesis that understanding cell and tissue (cell-tissue) interactions is crucial for achieving human-level performance, and to accelerate the research in this field. The challenge dataset includes overlapping cell detection and tissue segmentation annotations from six organs, comprising 673 pairs sourced from 306 The Cancer Genome Atlas (TCGA) Whole-Slide Images with hematoxylin and eosin staining, divided into training, validation, and test subsets. Participants presented models that significantly enhanced the understanding of cell-tissue relationships. Top entries achieved up to a 7.99 increase in F1-score on the test set compared to the baseline cell-only model that did not incorporate cell-tissue relationships. This is a substantial improvement in performance over traditional cell-only detection methods, demonstrating the need for incorporating multi-scale semantics into the models. This paper provides a comparative analysis of the methods used by participants, highlighting innovative strategies implemented in the OCELOT 2023 challenge.

Dual Enhancement on 3D Vision-Language Perception for Monocular 3D Visual Grounding

Monocular 3D visual grounding is a novel task that aims to locate 3D objects in RGB images using text descriptions with explicit geometry information. Despite the inclusion of geometry details in the text, we observe that the text embeddings are sensitive to the magnitude of numerical values but largely ignore the associated measurement units. For example, simply equidistant mapping the length with unit "meter" to "decimeters" or "centimeters" leads to severe performance degradation, even though the physical length remains equivalent. This observation signifies the weak 3D comprehension of pre-trained language model, which generates misguiding text features to hinder 3D perception. Therefore, we propose to enhance the 3D perception of model on text embeddings and geometry features with two simple and effective methods. Firstly, we introduce a pre-processing method named 3D-text Enhancement (3DTE), which enhances the comprehension of mapping relationships between different units by augmenting the diversity of distance descriptors in text queries. Next, we propose a Text-Guided Geometry Enhancement (TGE) module to further enhance the 3D-text information by projecting the basic text features into geometrically consistent space. These 3D-enhanced text features are then leveraged to precisely guide the attention of geometry features. We evaluate the proposed method through extensive comparisons and ablation studies on the Mono3DRefer dataset. Experimental results demonstrate substantial improvements over previous methods, achieving new state-of-the-art results with a notable accuracy gain of 11.94\% in the "Far" scenario. Our code will be made publicly available.

Bridging the Modality Gap: Enhancing Channel Prediction with Semantically Aligned LLMs and Knowledge Distillation

Accurate channel prediction is essential in massive multiple-input multiple-output (m-MIMO) systems to improve precoding effectiveness and reduce the overhead of channel state information (CSI) feedback. However, existing methods often suffer from accumulated prediction errors and poor generalization to dynamic wireless environments. Large language models (LLMs) have demonstrated remarkable modeling and generalization capabilities in tasks such as time series prediction, making them a promising solution. Nevertheless, a significant modality gap exists between the linguistic knowledge embedded in pretrained LLMs and the intrinsic characteristics of CSI, posing substantial challenges for their direct application to channel prediction. Moreover, the large parameter size of LLMs hinders their practical deployment in real-world communication systems with stringent latency constraints. To address these challenges, we propose a novel channel prediction framework based on semantically aligned large models, referred to as CSI-ALM, which bridges the modality gap between natural language and channel information. Specifically, we design a cross-modal fusion module that aligns CSI representations . Additionally, we maximize the cosine similarity between word embeddings and CSI embeddings to construct semantic cues. To reduce complexity and enable practical implementation, we further introduce a lightweight version of the proposed approach, called CSI-ALM-Light. This variant is derived via a knowledge distillation strategy based on attention matrices. Extensive experimental results demonstrate that CSI-ALM achieves a 1 dB gain over state-of-the-art deep learning methods. Moreover, under limited training data conditions, CSI-ALM-Light, with only 0.34M parameters, attains performance comparable to CSI-ALM and significantly outperforms conventional deep learning approaches.

KPIs 2024 Challenge: Advancing Glomerular Segmentation from Patch- to Slide-Level

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive benchmarks for kidney pathology segmentation hinders progress in the field. To address this, we organized the Kidney Pathology Image Segmentation (KPIs) Challenge, introducing a dataset that incorporates preclinical rodent models of CKD with over 10,000 annotated glomeruli from 60+ Periodic Acid Schiff (PAS)-stained whole slide images. The challenge includes two tasks, patch-level segmentation and whole slide image segmentation and detection, evaluated using the Dice Similarity Coefficient (DSC) and F1-score. By encouraging innovative segmentation methods that adapt to diverse CKD models and tissue conditions, the KPIs Challenge aims to advance kidney pathology analysis, establish new benchmarks, and enable precise, large-scale quantification for disease research and diagnosis.

When Should We Prefer State-to-Visual DAgger Over Visual Reinforcement Learning?

Learning policies from high-dimensional visual inputs, such as pixels and point clouds, is crucial in various applications. Visual reinforcement learning is a promising approach that directly trains policies from visual observations, although it faces challenges in sample efficiency and computational costs. This study conducts an empirical comparison of State-to-Visual DAgger, a two-stage framework that initially trains a state policy before adopting online imitation to learn a visual policy, and Visual RL across a diverse set of tasks. We evaluate both methods across 16 tasks from three benchmarks, focusing on their asymptotic performance, sample efficiency, and computational costs. Surprisingly, our findings reveal that State-to-Visual DAgger does not universally outperform Visual RL but shows significant advantages in challenging tasks, offering more consistent performance. In contrast, its benefits in sample efficiency are less pronounced, although it often reduces the overall wall-clock time required for training. Based on our findings, we provide recommendations for practitioners and hope that our results contribute valuable perspectives for future research in visual policy learning.

Evaluating and Advancing Multimodal Large Language Models in Ability Lens

As multimodal large language models (MLLMs) advance rapidly, rigorous evaluation has become essential, providing further guidance for their development. In this work, we focus on a unified and robust evaluation of \textbf{vision perception} abilities, the foundational skill of MLLMs. We find that existing perception benchmarks, each focusing on different question types, domains, and evaluation metrics, introduce significant evaluation variance, complicating comprehensive assessments of perception abilities when relying on any single benchmark. To address this, we introduce \textbf{AbilityLens}, a unified benchmark designed to evaluate MLLMs across six key perception abilities, focusing on both accuracy and stability, with each ability encompassing diverse question types, domains, and metrics. With the assistance of AbilityLens, we: (1) identify the strengths and weaknesses of current models, highlighting stability patterns and revealing a notable performance gap between open-source and closed-source models; (2) introduce an online evaluation mode, which uncovers interesting ability conflict and early convergence phenomena during MLLM training; and (3) design a simple ability-specific model merging method that combines the best ability checkpoint from early training stages, effectively mitigating performance decline due to ability conflict. The benchmark and online leaderboard will be released soon.

Effectively Enhancing Vision Language Large Models by Prompt Augmentation and Caption Utilization

Recent studies have shown that Vision Language Large Models (VLLMs) may output content not relevant to the input images. This problem, called the hallucination phenomenon, undoubtedly degrades VLLM performance. Therefore, various anti-hallucination techniques have been proposed to make model output more reasonable and accurate. Despite their successes, from extensive tests we found that augmenting the prompt (e.g. word appending, rewriting, and spell error etc.) may change model output and make the output hallucinate again. To cure this drawback, we propose a new instruct-tuning framework called Prompt Augmentation and Caption Utilization (PACU) to boost VLLM's generation ability under the augmented prompt scenario. Concretely, on the one hand, PACU exploits existing LLMs to augment and evaluate diverse prompts automatically. The resulting high-quality prompts are utilized to enhance VLLM's ability to process different prompts. On the other hand, PACU exploits image captions to jointly work with image features as well as the prompts for response generation. When the visual feature is inaccurate, LLM can capture useful information from the image captions for response generation. Extensive experiments on hallucination evaluation and prompt-augmented datasets demonstrate that our PACU method can work well with existing schemes to effectively boost VLLM model performance. Code is available in https://github.com/zhaominyiz/PACU.

Localization and Expansion: A Decoupled Framework for Point Cloud Few-shot Semantic Segmentation

Point cloud few-shot semantic segmentation (PC-FSS) aims to segment targets of novel categories in a given query point cloud with only a few annotated support samples. The current top-performing prototypical learning methods employ prototypes originating from support samples to direct the classification of query points. However, the inherent fragility of point-level matching and the prevalent intra-class diversity pose great challenges to this cross-instance matching paradigm, leading to erroneous background activations or incomplete target excavation. In this work, we propose a simple yet effective framework in the spirit of Decoupled Localization and Expansion (DLE). The proposed DLE, including a structural localization module (SLM) and a self-expansion module (SEM), enjoys several merits. First, structural information is injected into the matching process through the agent-level correlation in SLM, and the confident target region can thus be precisely located. Second, more reliable intra-object similarity is harnessed in SEM to derive the complete target, and the conservative expansion strategy is introduced to reasonably constrain the expansion. Extensive experiments on two challenging benchmarks under different settings demonstrate that DLE outperforms previous state-of-the-art approaches by large margins.

Dynamically Expanding Capacity of Autonomous Driving with Near-Miss Focused Training Framework

The long-tail distribution of real driving data poses challenges for training and testing autonomous vehicles (AV), where rare yet crucial safety-critical scenarios are infrequent. And virtual simulation offers a low-cost and efficient solution. This paper proposes a near-miss focused training framework for AV. Utilizing the driving scenario information provided by sensors in the simulator, we design novel reward functions, which enable background vehicles (BV) to generate near-miss scenarios and ensure gradients exist not only in collision-free scenes but also in collision scenarios. And then leveraging the Robust Adversarial Reinforcement Learning (RARL) framework for simultaneous training of AV and BV to gradually enhance AV and BV capabilities, as well as generating near-miss scenarios tailored to different levels of AV capabilities. Results from three testing strategies indicate that the proposed method generates scenarios closer to near-miss, thus enhancing the capabilities of both AVs and BVs throughout training.

The Multi-modality Cell Segmentation Challenge: Towards Universal Solutions

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyperparameters in different experimental settings. Here, we present a multi-modality cell segmentation benchmark, comprising over 1500 labeled images derived from more than 50 diverse biological experiments. The top participants developed a Transformer-based deep-learning algorithm that not only exceeds existing methods, but can also be applied to diverse microscopy images across imaging platforms and tissue types without manual parameter adjustments. This benchmark and the improved algorithm offer promising avenues for more accurate and versatile cell analysis in microscopy imaging.