UnPuzzle: A Unified Framework for Pathology Image Analysis

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks, the lack of standardization in pre-processing methods and model/database architectures complicates fair comparisons across different approaches. This highlights the need for a unified pipeline and comprehensive benchmarks to enable consistent evaluation and accelerate research progress. In this paper, we present UnPuzzle, a novel and unified framework for pathological AI research that covers a broad range of pathology tasks with benchmark results. From high-level to low-level, upstream to downstream tasks, UnPuzzle offers a modular pipeline that encompasses data pre-processing, model composition,taskconfiguration,andexperimentconduction.Specifically, it facilitates efficient benchmarking for both Whole Slide Images (WSIs) and Region of Interest (ROI) tasks. Moreover, the framework supports variouslearningparadigms,includingself-supervisedlearning,multi-task learning,andmulti-modallearning,enablingcomprehensivedevelopment of pathology AI models. Through extensive benchmarking across multiple datasets, we demonstrate the effectiveness of UnPuzzle in streamlining pathology AI research and promoting reproducibility. We envision UnPuzzle as a cornerstone for future advancements in pathology AI, providing a more accessible, transparent, and standardized approach to model evaluation. The UnPuzzle repository is publicly available at https://github.com/Puzzle-AI/UnPuzzle.

InfiR : Crafting Effective Small Language Models and Multimodal Small Language Models in Reasoning

Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs) have made significant advancements in reasoning capabilities. However, they still face challenges such as high computational demands and privacy concerns. This paper focuses on developing efficient Small Language Models (SLMs) and Multimodal Small Language Models (MSLMs) that retain competitive reasoning abilities. We introduce a novel training pipeline that enhances reasoning capabilities and facilitates deployment on edge devices, achieving state-of-the-art performance while minimizing development costs. \InfR~ aims to advance AI systems by improving reasoning, reducing adoption barriers, and addressing privacy concerns through smaller model sizes. Resources are available at https://github. com/Reallm-Labs/InfiR.

Fleximo: Towards Flexible Text-to-Human Motion Video Generation

Current methods for generating human motion videos rely on extracting pose sequences from reference videos, which restricts flexibility and control. Additionally, due to the limitations of pose detection techniques, the extracted pose sequences can sometimes be inaccurate, leading to low-quality video outputs. We introduce a novel task aimed at generating human motion videos solely from reference images and natural language. This approach offers greater flexibility and ease of use, as text is more accessible than the desired guidance videos. However, training an end-to-end model for this task requires millions of high-quality text and human motion video pairs, which are challenging to obtain. To address this, we propose a new framework called Fleximo, which leverages large-scale pre-trained text-to-3D motion models. This approach is not straightforward, as the text-generated skeletons may not consistently match the scale of the reference image and may lack detailed information. To overcome these challenges, we introduce an anchor point based rescale method and design a skeleton adapter to fill in missing details and bridge the gap between text-to-motion and motion-to-video generation. We also propose a video refinement process to further enhance video quality. A large language model (LLM) is employed to decompose natural language into discrete motion sequences, enabling the generation of motion videos of any desired length. To assess the performance of Fleximo, we introduce a new benchmark called MotionBench, which includes 400 videos across 20 identities and 20 motions. We also propose a new metric, MotionScore, to evaluate the accuracy of motion following. Both qualitative and quantitative results demonstrate that our method outperforms existing text-conditioned image-to-video generation methods. All code and model weights will be made publicly available.

DreamStory: Open-Domain Story Visualization by LLM-Guided Multi-Subject Consistent Diffusion

Story visualization aims to create visually compelling images or videos corresponding to textual narratives. Despite recent advances in diffusion models yielding promising results, existing methods still struggle to create a coherent sequence of subject-consistent frames based solely on a story. To this end, we propose DreamStory, an automatic open-domain story visualization framework by leveraging the LLMs and a novel multi-subject consistent diffusion model. DreamStory consists of (1) an LLM acting as a story director and (2) an innovative Multi-Subject consistent Diffusion model (MSD) for generating consistent multi-subject across the images. First, DreamStory employs the LLM to generate descriptive prompts for subjects and scenes aligned with the story, annotating each scene's subjects for subsequent subject-consistent generation. Second, DreamStory utilizes these detailed subject descriptions to create portraits of the subjects, with these portraits and their corresponding textual information serving as multimodal anchors (guidance). Finally, the MSD uses these multimodal anchors to generate story scenes with consistent multi-subject. Specifically, the MSD includes Masked Mutual Self-Attention (MMSA) and Masked Mutual Cross-Attention (MMCA) modules. MMSA and MMCA modules ensure appearance and semantic consistency with reference images and text, respectively. Both modules employ masking mechanisms to prevent subject blending. To validate our approach and promote progress in story visualization, we established a benchmark, DS-500, which can assess the overall performance of the story visualization framework, subject-identification accuracy, and the consistency of the generation model. Extensive experiments validate the effectiveness of DreamStory in both subjective and objective evaluations. Please visit our project homepage at https://dream-xyz.github.io/dreamstory.

Glyph-ByT5-v2: A Strong Aesthetic Baseline for Accurate Multilingual Visual Text Rendering

Recently, Glyph-ByT5 has achieved highly accurate visual text rendering performance in graphic design images. However, it still focuses solely on English and performs relatively poorly in terms of visual appeal. In this work, we address these two fundamental limitations by presenting Glyph-ByT5-v2 and Glyph-SDXL-v2, which not only support accurate visual text rendering for 10 different languages but also achieve much better aesthetic quality. To achieve this, we make the following contributions: (i) creating a high-quality multilingual glyph-text and graphic design dataset consisting of more than 1 million glyph-text pairs and 10 million graphic design image-text pairs covering nine other languages, (ii) building a multilingual visual paragraph benchmark consisting of 1,000 prompts, with 100 for each language, to assess multilingual visual spelling accuracy, and (iii) leveraging the latest step-aware preference learning approach to enhance the visual aesthetic quality. With the combination of these techniques, we deliver a powerful customized multilingual text encoder, Glyph-ByT5-v2, and a strong aesthetic graphic generation model, Glyph-SDXL-v2, that can support accurate spelling in 10 different languages. We perceive our work as a significant advancement, considering that the latest DALL-E3 and Ideogram 1.0 still struggle with the multilingual visual text rendering task.

AFLoRA: Adaptive Freezing of Low Rank Adaptation in Parameter Efficient Fine-Tuning of Large Models

We present a novel Parameter-Efficient Fine-Tuning (PEFT) method, dubbed as Adaptive Freezing of Low Rank Adaptation (AFLoRA). Specifically, for each pre-trained frozen weight tensor, we add a parallel path of trainable low-rank matrices, namely a down-projection and an up-projection matrix, each of which is followed by a feature transformation vector. Based on a novel freezing score, we the incrementally freeze these projection matrices during fine-tuning to reduce the computation and alleviate over-fitting. Our experimental results demonstrate that we can achieve state-of-the-art performance with an average improvement of up to $0.85\%$ as evaluated on GLUE benchmark while yeilding up to $9.5\times$ fewer average trainable parameters. While compared in terms of runtime, AFLoRA can yield up to $1.86\times$ improvement as opposed to similar PEFT alternatives. Besides the practical utility of our approach, we provide insights on the trainability requirements of LoRA paths at different modules and the freezing schedule for the different projection matrices. Code will be released.

Glyph-ByT5: A Customized Text Encoder for Accurate Visual Text Rendering

Visual text rendering poses a fundamental challenge for contemporary text-to-image generation models, with the core problem lying in text encoder deficiencies. To achieve accurate text rendering, we identify two crucial requirements for text encoders: character awareness and alignment with glyphs. Our solution involves crafting a series of customized text encoder, Glyph-ByT5, by fine-tuning the character-aware ByT5 encoder using a meticulously curated paired glyph-text dataset. We present an effective method for integrating Glyph-ByT5 with SDXL, resulting in the creation of the Glyph-SDXL model for design image generation. This significantly enhances text rendering accuracy, improving it from less than $20\%$ to nearly $90\%$ on our design image benchmark. Noteworthy is Glyph-SDXL's newfound ability for text paragraph rendering, achieving high spelling accuracy for tens to hundreds of characters with automated multi-line layouts. Finally, through fine-tuning Glyph-SDXL with a small set of high-quality, photorealistic images featuring visual text, we showcase a substantial improvement in scene text rendering capabilities in open-domain real images. These compelling outcomes aim to encourage further exploration in designing customized text encoders for diverse and challenging tasks.

LMUFormer: Low Complexity Yet Powerful Spiking Model With Legendre Memory Units

Transformer models have demonstrated high accuracy in numerous applications but have high complexity and lack sequential processing capability making them ill-suited for many streaming applications at the edge where devices are heavily resource-constrained. Thus motivated, many researchers have proposed reformulating the transformer models as RNN modules which modify the self-attention computation with explicit states. However, these approaches often incur significant performance degradation. The ultimate goal is to develop a model that has the following properties: parallel training, streaming and low-cost inference, and SOTA performance. In this paper, we propose a new direction to achieve this goal. We show how architectural modifications to a recurrent model can help push its performance toward Transformer models while retaining its sequential processing capability. Specifically, inspired by the recent success of Legendre Memory Units (LMU) in sequence learning tasks, we propose LMUFormer, which augments the LMU with convolutional patch embedding and convolutional channel mixer. Moreover, we present a spiking version of this architecture, which introduces the benefit of states within the patch embedding and channel mixer modules while simultaneously reducing the computing complexity. We evaluated our architectures on multiple sequence datasets. In comparison to SOTA transformer-based models within the ANN domain on the SCv2 dataset, our LMUFormer demonstrates comparable performance while necessitating a remarkable 53 times reduction in parameters and a substantial 65 times decrement in FLOPs. Additionally, owing to our model's proficiency in real-time data processing, we can achieve a 32.03% reduction in sequence length, all while incurring an inconsequential decline in performance. Our code is publicly available at https://github.com/zeyuliu1037/LMUFormer.git.

When Bio-Inspired Computing meets Deep Learning: Low-Latency, Accurate, & Energy-Efficient Spiking Neural Networks from Artificial Neural Networks

Bio-inspired Spiking Neural Networks (SNN) are now demonstrating comparable accuracy to intricate convolutional neural networks (CNN), all while delivering remarkable energy and latency efficiency when deployed on neuromorphic hardware. In particular, ANN-to-SNN conversion has recently gained significant traction in developing deep SNNs with close to state-of-the-art (SOTA) test accuracy on complex image recognition tasks. However, advanced ANN-to-SNN conversion approaches demonstrate that for lossless conversion, the number of SNN time steps must equal the number of quantization steps in the ANN activation function. Reducing the number of time steps significantly increases the conversion error. Moreover, the spiking activity of the SNN, which dominates the compute energy in neuromorphic chips, does not reduce proportionally with the number of time steps. To mitigate the accuracy concern, we propose a novel ANN-to-SNN conversion framework, that incurs an exponentially lower number of time steps compared to that required in the SOTA conversion approaches. Our framework modifies the SNN integrate-and-fire (IF) neuron model with identical complexity and shifts the bias term of each batch normalization (BN) layer in the trained ANN. To mitigate the spiking activity concern, we propose training the source ANN with a fine-grained L1 regularizer with surrogate gradients that encourages high spike sparsity in the converted SNN. Our proposed framework thus yields lossless SNNs with ultra-low latency, ultra-low compute energy, thanks to the ultra-low timesteps and high spike sparsity, and ultra-high test accuracy, for example, 73.30% with only 4 time steps on the ImageNet dataset.

COLE: A Hierarchical Generation Framework for Graphic Design

Graphic design, which has been evolving since the 15th century, plays a crucial role in advertising. The creation of high-quality designs demands creativity, innovation, and lateral thinking. This intricate task involves understanding the objective, crafting visual elements such as the background, decoration, font, color, and shape, formulating diverse professional layouts, and adhering to fundamental visual design principles. In this paper, we introduce COLE, a hierarchical generation framework designed to comprehensively address these challenges. This COLE system can transform a straightforward intention prompt into a high-quality graphic design, while also supporting flexible editing based on user input. Examples of such input might include directives like ``design a poster for Hisaishi's concert.'' The key insight is to dissect the complex task of text-to-design generation into a hierarchy of simpler sub-tasks, each addressed by specialized models working collaboratively. The results from these models are then consolidated to produce a cohesive final output. Our hierarchical task decomposition can streamline the complex process and significantly enhance generation reliability. Our COLE system consists of multiple fine-tuned Large Language Models (LLMs), Large Multimodal Models (LMMs), and Diffusion Models (DMs), each specifically tailored for a design-aware text or image generation task. Furthermore, we construct the DESIGNERINTENTION benchmark to highlight the superiority of our COLE over existing methods in generating high-quality graphic designs from user intent. We perceive our COLE as an important step towards addressing more complex visual design generation tasks in the future.