Abstract:Multimodal document retrieval--selecting the most relevant multimodal document from a large corpus to answer a natural language query--plays an essential role in Retrieval-Augmented Generation (RAG) systems. State-of-the-art methods represent each document and query with multiple token-level embeddings and use late interaction to achieve high effectiveness. However, such multi-vector representations incur substantial memory overhead during retrieval, leading to poor scalability and hindering real-world deployment. In this paper, we present Stellar, a scalable multimodal document retrieval framework that stores token-level document embeddings on disk and loads only a small set of candidate embeddings into memory for late interaction. Stellar comprises two key components: (i) Lexical Representation-based Filtering (LRF), which fine-tunes a Multimodal Large Language Model (MLLM) as a sparse encoder to produce high-quality lexical representations, enabling efficient and effective document filtering to significantly reduce the candidate set; (ii) Efficient Disk-backed Late Interaction (DLI), which designs an on-disk token embedding storage layout guided by a balanced clustering algorithm, and dynamically loads only the necessary token embeddings into memory using a simple yet effective cost model. Extensive experiments on four real-world benchmarks and a newly presented large-scale dataset demonstrate that Stellar reduces memory overhead and query latency by 1-2 orders of magnitude compared to existing methods without compromising retrieval effectiveness.
Abstract:Graph neural networks (GNNs) excel at aggregating neighbor information for classification, yet their performance is hindered by graph structural entanglement, where spurious correlations from semantically irrelevant neighbors contaminate node embeddings. This challenge is most acute for nodes near class boundaries in the embedding space, where amplified structural noise blurs decision boundaries and destabilizes predictions. Existing robust GNN methods largely treat all nodes uniformly, ignoring boundary vulnerabilities. In this paper, to improve classification performance, we tackle graph structural disentanglement by identifying boundary-region entanglement as the primary bottleneck and propose Boundary Embedding Shaping (BES), an adaptive contrastive learning GNN plug-in module that selectively suppresses spurious structural noise at decision boundaries with minimal model parameter perturbation. Extensive experiments demonstrate that BES consistently improves boundary discrimination and outperforms existing leading methods. Notably, BES boosts GCN performance by an average of 3.3% in node classification (up to 5.0% on WikiCS) and achieves superior accuracy in link prediction.
Abstract:Large Language Models (LLMs) demonstrate remarkable potential in dynamic graph reasoning, but suffer from a scaling bottleneck: current models can only handle graphs with tens of nodes, constrained by exponential reasoning overhead and finite context windows. While multi-agent systems (MAS) offer collective reasoning and topology-aware orchestration, capabilities naturally suited for graph-structured tasks, their application to dynamic graphs remains unexplored. This paper presents Scaling LLM Reasoning on Dynamic Graphs via Adaptive Spatio-Temporal Multi-Agent Collaboration (AdaSTORM), a framework that reformulates large-scale dynamic graph reasoning into two stages: (i) Adaptive Partitioning, partitioning large-scale dynamic graphs into subregions that match the model's reasoning capacity while minimizing inference cost; and (ii) Collaborative Reasoning, aligning graph partition topologies with a spatio-temporal decoupled multi-agent architecture. AdaSTORM is the first multi-agent framework tailored for dynamic graph reasoning. Extensive experiments show that AdaSTORM successfully breaks through the scaling bottleneck, scaling reasoning to thousand-node graphs with over 90% accuracy across several large-scale dynamic graph settings without external tools, significantly outperforms seven competitive baselines. Furthermore, it achieves state-of-the-art accuracy on existing benchmarks and generalizes robustly to real-world datasets. The source code is available at: https://github.com/irisorchid107/AdaSTORM/.
Abstract:Single-cell perturbation prediction aims to infer how cells respond to unseen interventions and to achieve out-of-distribution (OOD) generalization, providing a computational route to understanding how perturbations reshape cellular programs over time. Existing machine learning methods have made important progress, but typically capture only one side of the response. Latent causal approaches seek mechanisms that support generalization and interpretation, yet often treat perturbation effects as static outcomes. Temporal models describe how gene expression changes across time, but usually do not explicitly recover the latent causal generative mechanisms driving these changes. In practice, perturbation effects are both latent and dynamical: interventions act through unobserved cellular programs, whose states evolve over time and give rise to observed expression profiles. Motivated by this view, we propose a latent dynamical causal generative model for single-cell perturbation data that jointly captures latent cellular programs, perturbation-conditioned mechanisms, and temporal evolution. We further provide an identifiability analysis showing that, under suitable conditions, the latent causal variables are recoverable up to standard equivalence classes. Guided by this analysis, we develop CITE-VAE, a learning framework for recovering latent cellular programs and their perturbation-driven dynamics from single-cell sequencing data. Experiments on Causal-3DIdent validate the theoretical results and the effectiveness of the proposed method in controlled settings. Additional experiments on real-world CRISPR-based single-cell perturbation data show improved generalization to unseen perturbations compared with state-of-the-art baselines, highlighting the practical robustness of our approach.
Abstract:Pre-training on text-attributed graphs (TAGs) is central to building transferable graph foundation models, where LLM-as-Aligner methods align graph and text representations through the semantic knowledge of large language models. However, these methods usually assume that node texts provide sufficient and reliable supervision, an assumption often violated in real-world sparse TAGs. When textual anchors are missing, noisy, or uneven across domains, graph structures must be aligned with weak semantic evidence, leading to unreliable structure-semantics correspondence and sparsity-induced transfer bias. This paper presents S2Aligner, a sparsity-aware and structure-enhanced LLM-as-Aligner framework for graph-text pre-training on sparse TAGs. The key idea is to decouple semantic alignment from structural modeling, allowing topology-aware signals to enhance alignment without contaminating the shared semantic space. Specifically, S2Aligner decomposes graph-text representations into semantic and structural components, uses structure-oriented reconstruction with consistency control to inject reliable topology cues into text representations, and suppresses inconsistent structural signals under textual sparsity. Moreover, S2Aligner introduces sparsity-aware cross-domain risk balancing, which calibrates domain risks through a global-domain density ratio and downweights unreliable sparse samples via graph reliability estimation. Theoretical analysis shows that this objective reduces cross-domain generalization gaps by controlling domain risk discrepancy. Extensive experiments across diverse graph domains, sparsity levels, and downstream tasks demonstrate that S2Aligner consistently outperforms existing baselines.
Abstract:Single-cell perturbation modeling is fundamental for understanding and predicting cellular responses to genetic perturbations. However, existing approaches, from causal representation learning to foundation models, often struggle with an overlooked challenge: gene expression is dominated by perturbation-invariant information, while perturbation-specific signals are intrinsically sparse. As a result, learned representations either entangle invariant and perturbation-specific information, leading to spurious and non-generalizable predictors, or suppress perturbation-specific signals altogether, rendering them ineffective for prediction. To address this, we propose PerturbedVAE, a general framework designed to resolve this signal imbalance. The framework explicitly separates perturbation-specific information from dominant invariant structure and recovers causal representations to effectively utilize such information for prediction. We further provide an identifiability analysis that characterizes the conditions under which sparse perturbation effects can be reliably recovered, thereby clarifying how the framework can be concretely specified under such conditions. Empirically, PerturbedVAE achieves state-of-the-art performance on a widely used benchmark across multiple evaluation settings, yielding significant gains on out-of-distribution combinatorial predictions and uncovering interpretable perturbation-response programs.
Abstract:Large language models have demonstrated remarkable capabilities across a wide range of natural language processing tasks, yet their application in the legal domain remains challenging due to the specialized terminology, complex reasoning requirements, and rapidly evolving legal knowledge involved. In this paper, we present WisdomInterrogatory (LuWen), an open-source Chinese legal language model built upon the Baichuan foundation model through three key techniques: continual pre-training on a large-scale legal corpus, supervised fine-tuning with carefully curated legal instruction data, and retrieval-augmented generation integrated with a comprehensive legal knowledge base. We evaluate LuWen on five representative legal tasks spanning both prediction and generation settings, including legal judgment prediction, judicial examination, legal text summarization, law article question answering, and judicial decision reasoning. Experimental results show that LuWen outperforms several strong baselines, demonstrating the effectiveness of our approach in adapting general-purpose language models to the legal domain.
Abstract:Large language models have demonstrated remarkable capabilities across a wide range of natural language processing tasks, yet their application in the legal domain remains challenging due to the specialized terminology, complex reasoning requirements, and rapidly evolving legal knowledge involved. In this paper, we present Luwen, an open-source Chinese legal language model built upon the Baichuan foundation model through three key techniques: continual pre-training on a large-scale legal corpus, supervised fine-tuning with carefully curated legal instruction data, and retrieval-augmented generation integrated with a comprehensive legal knowledge base. We evaluate Luwen on five representative legal tasks spanning both prediction and generation settings, including legal judgment prediction, judicial examination, legal text summarization, law article question answering, and judicial decision reasoning. Experimental results show that Luwen outperforms several strong baselines, demonstrating the effectiveness of our approach in adapting general-purpose language models to the legal domain.
Abstract:Large language models (LLMs) have achieved strong performance on reasoning benchmarks, yet their ability to solve real-world problems requiring end-to-end workflows remains unclear. Mathematical modeling competitions provide a stringent testbed for evaluating such end-to-end problem-solving capability. We propose a problem-oriented, stage-wise evaluation framework that assesses LLM performance across modeling stages using expert-verified criteria. We validate the framework's reliability by comparing automatic scores with independent human expert judgments on problems from the China Postgraduate Mathematical Contest in Modeling, demonstrating substantially stronger alignment than existing evaluation schemes. Using this framework, we reveal a comprehension-execution gap in state-of-the-art LLMs: while they perform well in early stages such as problem identification and formulation, they exhibit persistent deficiencies in execution-oriented stages including model solving, code implementation, and result analysis. These gaps persist even with increased model scale. We further trace these failures to insufficient specification, missing verification, and lack of validation, with errors propagating across stages without correction. Our findings suggest that bridging this gap requires approaches beyond model scaling, offering insights for applying LLMs to complex real-world problem solving.
Abstract:In-Context Learning (ICL) is a significant paradigm for Large Multimodal Models (LMMs), using a few in-context demonstrations (ICDs) for new task adaptation. However, its performance is sensitive to demonstration configurations and computationally expensive. Mathematically, the influence of these demonstrations can be decomposed into a dynamic mixture of the standard attention output and the context values. Current approximation methods simplify this process by learning a "shift vector". Inspired by the exact decomposition, we introduce High-Fidelity In-Context Learning (HIFICL) to more faithfully model the ICL mechanism. HIFICL consists of three key components: 1) a set of "virtual key-value pairs" to act as a learnable context, 2) a low-rank factorization for stable and regularized training, and 3) a simple end-to-end training objective. From another perspective, this mechanism constitutes a form of context-aware Parameter-Efficient Fine-Tuning (PEFT). Extensive experiments show that HiFICL consistently outperforms existing approximation methods on several multimodal benchmarks. The code is available at https://github.com/bbbandari/HiFICL.