AttriPrompter: Auto-Prompting with Attribute Semantics for Zero-shot Nuclei Detection via Visual-Language Pre-trained Models

Large-scale visual-language pre-trained models (VLPMs) have demonstrated exceptional performance in downstream object detection through text prompts for natural scenes. However, their application to zero-shot nuclei detection on histopathology images remains relatively unexplored, mainly due to the significant gap between the characteristics of medical images and the web-originated text-image pairs used for pre-training. This paper aims to investigate the potential of the object-level VLPM, Grounded Language-Image Pre-training (GLIP), for zero-shot nuclei detection. Specifically, we propose an innovative auto-prompting pipeline, named AttriPrompter, comprising attribute generation, attribute augmentation, and relevance sorting, to avoid subjective manual prompt design. AttriPrompter utilizes VLPMs' text-to-image alignment to create semantically rich text prompts, which are then fed into GLIP for initial zero-shot nuclei detection. Additionally, we propose a self-trained knowledge distillation framework, where GLIP serves as the teacher with its initial predictions used as pseudo labels, to address the challenges posed by high nuclei density, including missed detections, false positives, and overlapping instances. Our method exhibits remarkable performance in label-free nuclei detection, outperforming all existing unsupervised methods and demonstrating excellent generality. Notably, this work highlights the astonishing potential of VLPMs pre-trained on natural image-text pairs for downstream tasks in the medical field as well. Code will be released at https://github.com/wuyongjianCODE/AttriPrompter.

Hierarchical Hybrid Learning for Long-Horizon Contact-Rich Robotic Assembly

Generalizable long-horizon robotic assembly requires reasoning at multiple levels of abstraction. End-to-end imitation learning (IL) has been proven a promising approach, but it requires a large amount of demonstration data for training and often fails to meet the high-precision requirement of assembly tasks. Reinforcement Learning (RL) approaches have succeeded in high-precision assembly tasks, but suffer from sample inefficiency and hence, are less competent at long-horizon tasks. To address these challenges, we propose a hierarchical modular approach, named ARCH (Adaptive Robotic Composition Hierarchy), which enables long-horizon high-precision assembly in contact-rich settings. ARCH employs a hierarchical planning framework, including a low-level primitive library of continuously parameterized skills and a high-level policy. The low-level primitive library includes essential skills for assembly tasks, such as grasping and inserting. These primitives consist of both RL and model-based controllers. The high-level policy, learned via imitation learning from a handful of demonstrations, selects the appropriate primitive skills and instantiates them with continuous input parameters. We extensively evaluate our approach on a real robot manipulation platform. We show that while trained on a single task, ARCH generalizes well to unseen tasks and outperforms baseline methods in terms of success rate and data efficiency. Videos can be found at https://long-horizon-assembly.github.io.

SDPT: Synchronous Dual Prompt Tuning for Fusion-based Visual-Language Pre-trained Models

Prompt tuning methods have achieved remarkable success in parameter-efficient fine-tuning on large pre-trained models. However, their application to dual-modal fusion-based visual-language pre-trained models (VLPMs), such as GLIP, has encountered issues. Existing prompt tuning methods have not effectively addressed the modal mapping and aligning problem for tokens in different modalities, leading to poor transfer generalization. To address this issue, we propose Synchronous Dual Prompt Tuning (SDPT). SDPT initializes a single set of learnable unified prototype tokens in the established modal aligning space to represent the aligned semantics of text and image modalities for downstream tasks. Furthermore, SDPT establishes inverse linear projections that require no training to embed the information of unified prototype tokens into the input space of different modalities. The inverse linear projections allow the unified prototype token to synchronously represent the two modalities and enable SDPT to share the unified semantics of text and image for downstream tasks across different modal prompts. Experimental results demonstrate that SDPT assists fusion-based VLPMs to achieve superior outcomes with only 0.04\% of model parameters for training across various scenarios, outperforming other single- or dual-modal methods. The code will be released at https://github.com/wuyongjianCODE/SDPT.

Restore-RWKV: Efficient and Effective Medical Image Restoration with RWKV

Transformers have revolutionized medical image restoration, but the quadratic complexity still poses limitations for their application to high-resolution medical images. The recent advent of RWKV in the NLP field has attracted much attention as it can process long sequences efficiently. To leverage its advanced design, we propose Restore-RWKV, the first RWKV-based model for medical image restoration. Since the original RWKV model is designed for 1D sequences, we make two necessary modifications for modeling spatial relations in 2D images. First, we present a recurrent WKV (Re-WKV) attention mechanism that captures global dependencies with linear computational complexity. Re-WKV incorporates bidirectional attention as basic for a global receptive field and recurrent attention to effectively model 2D dependencies from various scan directions. Second, we develop an omnidirectional token shift (Omni-Shift) layer that enhances local dependencies by shifting tokens from all directions and across a wide context range. These adaptations make the proposed Restore-RWKV an efficient and effective model for medical image restoration. Extensive experiments demonstrate that Restore-RWKV achieves superior performance across various medical image restoration tasks, including MRI image super-resolution, CT image denoising, PET image synthesis, and all-in-one medical image restoration. Code is available at: \href{https://github.com/Yaziwel/Restore-RWKV.git}{https://github.com/Yaziwel/Restore-RWKV}.

Region Attention Transformer for Medical Image Restoration

Transformer-based methods have demonstrated impressive results in medical image restoration, attributed to the multi-head self-attention (MSA) mechanism in the spatial dimension. However, the majority of existing Transformers conduct attention within fixed and coarsely partitioned regions (\text{e.g.} the entire image or fixed patches), resulting in interference from irrelevant regions and fragmentation of continuous image content. To overcome these challenges, we introduce a novel Region Attention Transformer (RAT) that utilizes a region-based multi-head self-attention mechanism (R-MSA). The R-MSA dynamically partitions the input image into non-overlapping semantic regions using the robust Segment Anything Model (SAM) and then performs self-attention within these regions. This region partitioning is more flexible and interpretable, ensuring that only pixels from similar semantic regions complement each other, thereby eliminating interference from irrelevant regions. Moreover, we introduce a focal region loss to guide our model to adaptively focus on recovering high-difficulty regions. Extensive experiments demonstrate the effectiveness of RAT in various medical image restoration tasks, including PET image synthesis, CT image denoising, and pathological image super-resolution. Code is available at \href{https://github.com/Yaziwel/Region-Attention-Transformer-for-Medical-Image-Restoration.git}{https://github.com/RAT}.

Machine Learning for Economic Forecasting: An Application to China's GDP Growth

This paper aims to explore the application of machine learning in forecasting Chinese macroeconomic variables. Specifically, it employs various machine learning models to predict the quarterly real GDP growth of China, and analyzes the factors contributing to the performance differences among these models. Our findings indicate that the average forecast errors of machine learning models are generally lower than those of traditional econometric models or expert forecasts, particularly in periods of economic stability. However, during certain inflection points, although machine learning models still outperform traditional econometric models, expert forecasts may exhibit greater accuracy in some instances due to experts' more comprehensive understanding of the macroeconomic environment and real-time economic variables. In addition to macroeconomic forecasting, this paper employs interpretable machine learning methods to identify the key attributive variables from different machine learning models, aiming to enhance the understanding and evaluation of their contributions to macroeconomic fluctuations.

SEACrowd: A Multilingual Multimodal Data Hub and Benchmark Suite for Southeast Asian Languages

Southeast Asia (SEA) is a region rich in linguistic diversity and cultural variety, with over 1,300 indigenous languages and a population of 671 million people. However, prevailing AI models suffer from a significant lack of representation of texts, images, and audio datasets from SEA, compromising the quality of AI models for SEA languages. Evaluating models for SEA languages is challenging due to the scarcity of high-quality datasets, compounded by the dominance of English training data, raising concerns about potential cultural misrepresentation. To address these challenges, we introduce SEACrowd, a collaborative initiative that consolidates a comprehensive resource hub that fills the resource gap by providing standardized corpora in nearly 1,000 SEA languages across three modalities. Through our SEACrowd benchmarks, we assess the quality of AI models on 36 indigenous languages across 13 tasks, offering valuable insights into the current AI landscape in SEA. Furthermore, we propose strategies to facilitate greater AI advancements, maximizing potential utility and resource equity for the future of AI in SEA.

All-In-One Medical Image Restoration via Task-Adaptive Routing

Although single-task medical image restoration (MedIR) has witnessed remarkable success, the limited generalizability of these methods poses a substantial obstacle to wider application. In this paper, we focus on the task of all-in-one medical image restoration, aiming to address multiple distinct MedIR tasks with a single universal model. Nonetheless, due to significant differences between different MedIR tasks, training a universal model often encounters task interference issues, where different tasks with shared parameters may conflict with each other in the gradient update direction. This task interference leads to deviation of the model update direction from the optimal path, thereby affecting the model's performance. To tackle this issue, we propose a task-adaptive routing strategy, allowing conflicting tasks to select different network paths in spatial and channel dimensions, thereby mitigating task interference. Experimental results demonstrate that our proposed \textbf{A}ll-in-one \textbf{M}edical \textbf{I}mage \textbf{R}estoration (\textbf{AMIR}) network achieves state-of-the-art performance in three MedIR tasks: MRI super-resolution, CT denoising, and PET synthesis, both in single-task and all-in-one settings. The code and data will be available at \href{https://github.com/Yaziwel/All-In-One-Medical-Image-Restoration-via-Task-Adaptive-Routing.git}{https://github.com/Yaziwel/AMIR}.

SkinCAP: A Multi-modal Dermatology Dataset Annotated with Rich Medical Captions

With the widespread application of artificial intelligence (AI), particularly deep learning (DL) and vision-based large language models (VLLMs), in skin disease diagnosis, the need for interpretability becomes crucial. However, existing dermatology datasets are limited in their inclusion of concept-level meta-labels, and none offer rich medical descriptions in natural language. This deficiency impedes the advancement of LLM-based methods in dermatological diagnosis. To address this gap and provide a meticulously annotated dermatology dataset with comprehensive natural language descriptions, we introduce SkinCAP: a multi-modal dermatology dataset annotated with rich medical captions. SkinCAP comprises 4,000 images sourced from the Fitzpatrick 17k skin disease dataset and the Diverse Dermatology Images dataset, annotated by board-certified dermatologists to provide extensive medical descriptions and captions. Notably, SkinCAP represents the world's first such dataset and is publicly available at https://huggingface.co/datasets/joshuachou/SkinCAP.

OmniActions: Predicting Digital Actions in Response to Real-World Multimodal Sensory Inputs with LLMs

The progression to "Pervasive Augmented Reality" envisions easy access to multimodal information continuously. However, in many everyday scenarios, users are occupied physically, cognitively or socially. This may increase the friction to act upon the multimodal information that users encounter in the world. To reduce such friction, future interactive interfaces should intelligently provide quick access to digital actions based on users' context. To explore the range of possible digital actions, we conducted a diary study that required participants to capture and share the media that they intended to perform actions on (e.g., images or audio), along with their desired actions and other contextual information. Using this data, we generated a holistic design space of digital follow-up actions that could be performed in response to different types of multimodal sensory inputs. We then designed OmniActions, a pipeline powered by large language models (LLMs) that processes multimodal sensory inputs and predicts follow-up actions on the target information grounded in the derived design space. Using the empirical data collected in the diary study, we performed quantitative evaluations on three variations of LLM techniques (intent classification, in-context learning and finetuning) and identified the most effective technique for our task. Additionally, as an instantiation of the pipeline, we developed an interactive prototype and reported preliminary user feedback about how people perceive and react to the action predictions and its errors.