SemiSAM+: Rethinking Semi-Supervised Medical Image Segmentation in the Era of Foundation Models

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an appealing strategy due to its less dependence on acquiring abundant annotations from experts compared to fully supervised methods. Beyond existing model-centric advancements of SSL by designing novel regularization strategies, we anticipate a paradigmatic shift due to the emergence of promptable segmentation foundation models with universal segmentation capabilities using positional prompts represented by Segment Anything Model (SAM). In this paper, we present SemiSAM+, a foundation model-driven SSL framework to efficiently learn from limited labeled data for medical image segmentation. SemiSAM+ consists of one or multiple promptable foundation models as generalist models, and a trainable task-specific segmentation model as specialist model. For a given new segmentation task, the training is based on the specialist-generalist collaborative learning procedure, where the trainable specialist model delivers positional prompts to interact with the frozen generalist models to acquire pseudo-labels, and then the generalist model output provides the specialist model with informative and efficient supervision which benefits the automatic segmentation and prompt generation in turn. Extensive experiments on two public datasets and one in-house clinical dataset demonstrate that SemiSAM+ achieves significant performance improvement, especially under extremely limited annotation scenarios, and shows strong efficiency as a plug-and-play strategy that can be easily adapted to different specialist and generalist models.

Inference Computation Scaling for Feature Augmentation in Recommendation Systems

Large language models have become a powerful method for feature augmentation in recommendation systems. However, existing approaches relying on quick inference often suffer from incomplete feature coverage and insufficient specificity in feature descriptions, limiting their ability to capture fine-grained user preferences and undermining overall performance. Motivated by the recent success of inference scaling in math and coding tasks, we explore whether scaling inference can address these limitations and enhance feature quality. Our experiments show that scaling inference leads to significant improvements in recommendation performance, with a 12% increase in NDCG@10. The gains can be attributed to two key factors: feature quantity and specificity. In particular, models using extended Chain-of-Thought (CoT) reasoning generate a greater number of detailed and precise features, offering deeper insights into user preferences and overcoming the limitations of quick inference. We further investigate the factors influencing feature quantity, revealing that model choice and search strategy play critical roles in generating a richer and more diverse feature set. This is the first work to apply inference scaling to feature augmentation in recommendation systems, bridging advances in reasoning tasks to enhance personalized recommendation.

SegAnyPET: Universal Promptable Segmentation from Positron Emission Tomography Images

Positron Emission Tomography (PET) imaging plays a crucial role in modern medical diagnostics by revealing the metabolic processes within a patient's body, which is essential for quantification of therapy response and monitoring treatment progress. However, the segmentation of PET images presents unique challenges due to their lower contrast and less distinct boundaries compared to other structural medical modalities. Recent developments in segmentation foundation models have shown superior versatility across diverse natural image segmentation tasks. Despite the efforts of medical adaptations, these works primarily focus on structural medical images with detailed physiological structural information and exhibit poor generalization ability when adapted to molecular PET imaging. In this paper, we collect and construct PETS-5k, the largest PET segmentation dataset to date, comprising 5,731 three-dimensional whole-body PET images and encompassing over 1.3M 2D images. Based on the established dataset, we develop SegAnyPET, a modality-specific 3D foundation model for universal promptable segmentation from PET images. To issue the challenge of discrepant annotation quality of PET images, we adopt a cross prompting confident learning (CPCL) strategy with an uncertainty-guided self-rectification process to robustly learn segmentation from high-quality labeled data and low-quality noisy labeled data. Experimental results demonstrate that SegAnyPET can correctly segment seen and unseen targets using only one or a few prompt points, outperforming state-of-the-art foundation models and task-specific fully supervised models with higher accuracy and strong generalization ability for universal segmentation. As the first foundation model for PET images, we believe that SegAnyPET will advance the applications to various downstream tasks for molecular imaging.

Beyond the Singular: The Essential Role of Multiple Generations in Effective Benchmark Evaluation and Analysis

Large language models (LLMs) have demonstrated significant utilities in real-world applications, exhibiting impressive capabilities in natural language processing and understanding. Benchmark evaluations are crucial for assessing the capabilities of LLMs as they can provide a comprehensive assessment of their strengths and weaknesses. However, current evaluation methods often overlook the inherent randomness of LLMs by employing deterministic generation strategies or relying on a single random sample, resulting in unaccounted sampling variance and unreliable benchmark score estimates. In this paper, we propose a hierarchical statistical model that provides a more comprehensive representation of the benchmarking process by incorporating both benchmark characteristics and LLM randomness. We show that leveraging multiple generations improves the accuracy of estimating the benchmark score and reduces variance. We also introduce $\mathbb P\left(\text{correct}\right)$, a prompt-level difficulty score based on correct ratios, providing fine-grained insights into individual prompts. Additionally, we create a data map that visualizes difficulty and semantic prompts, enabling error detection and quality control in benchmark construction.

Adaptive Pruning for Large Language Models with Structural Importance Awareness

The recent advancements in large language models (LLMs) have significantly improved language understanding and generation capabilities. However, it is difficult to deploy LLMs on resource-constrained edge devices due to their high computational and storage resource demands. To address this issue, we propose a novel LLM model pruning method, namely structurally-aware adaptive pruning (SAAP), to significantly reduce the computational and memory costs while maintaining model performance. We first define an adaptive importance fusion metric to evaluate the importance of all coupled structures in LLMs by considering their homoscedastic uncertainty. Then, we rank the importance of all modules to determine the specific layers that should be pruned to meet particular performance requirements. Furthermore, we develop a new group fine-tuning strategy to improve the inference efficiency of LLMs. Finally, we evaluate the proposed SAAP method on multiple LLMs across two common tasks, i.e., zero-shot classification and text generation. Experimental results show that our SAAP method outperforms several state-of-the-art baseline methods, achieving 2.17%, 2.37%, and 2.39% accuracy gains on LLaMA-7B, Vicuna-7B, and LLaMA-13B. Additionally, SAAP improves the token generation speed by 5%, showcasing its practical advantages in resource-constrained scenarios.

INSIGHT: Explainable Weakly-Supervised Medical Image Analysis

Due to their large sizes, volumetric scans and whole-slide pathology images (WSIs) are often processed by extracting embeddings from local regions and then an aggregator makes predictions from this set. However, current methods require post-hoc visualization techniques (e.g., Grad-CAM) and often fail to localize small yet clinically crucial details. To address these limitations, we introduce INSIGHT, a novel weakly-supervised aggregator that integrates heatmap generation as an inductive bias. Starting from pre-trained feature maps, INSIGHT employs a detection module with small convolutional kernels to capture fine details and a context module with a broader receptive field to suppress local false positives. The resulting internal heatmap highlights diagnostically relevant regions. On CT and WSI benchmarks, INSIGHT achieves state-of-the-art classification results and high weakly-labeled semantic segmentation performance. Project website and code are available at: https://zhangdylan83.github.io/ewsmia/

Bootstraping Clustering of Gaussians for View-consistent 3D Scene Understanding

Injecting semantics into 3D Gaussian Splatting (3DGS) has recently garnered significant attention. While current approaches typically distill 3D semantic features from 2D foundational models (e.g., CLIP and SAM) to facilitate novel view segmentation and semantic understanding, their heavy reliance on 2D supervision can undermine cross-view semantic consistency and necessitate complex data preparation processes, therefore hindering view-consistent scene understanding. In this work, we present FreeGS, an unsupervised semantic-embedded 3DGS framework that achieves view-consistent 3D scene understanding without the need for 2D labels. Instead of directly learning semantic features, we introduce the IDentity-coupled Semantic Field (IDSF) into 3DGS, which captures both semantic representations and view-consistent instance indices for each Gaussian. We optimize IDSF with a two-step alternating strategy: semantics help to extract coherent instances in 3D space, while the resulting instances regularize the injection of stable semantics from 2D space. Additionally, we adopt a 2D-3D joint contrastive loss to enhance the complementarity between view-consistent 3D geometry and rich semantics during the bootstrapping process, enabling FreeGS to uniformly perform tasks such as novel-view semantic segmentation, object selection, and 3D object detection. Extensive experiments on LERF-Mask, 3D-OVS, and ScanNet datasets demonstrate that FreeGS performs comparably to state-of-the-art methods while avoiding the complex data preprocessing workload.

Code-mixed LLM: Improve Large Language Models' Capability to Handle Code-Mixing through Reinforcement Learning from AI Feedback

Code-mixing(CM) or code-switching(CSW) refers to the juxtaposition of linguistic units from two or more languages during the conversation or sometimes even a single utterance. Code-mixing introduces unique challenges in daily life, such as syntactic mismatches and semantic blending, that are rarely encountered in monolingual settings. Large language models (LLMs) have revolutionized the field of natural language processing (NLP) by offering unprecedented capabilities in understanding human languages. However, the effectiveness of current state-of-the-art multilingual LLMs has not yet been fully explored in the CM scenario. To fill this gap, we first benchmark the performance of multilingual LLMs on various code-mixing NLP tasks. Then we propose to improve the multilingual LLMs' ability to understand code-mixing through reinforcement learning from human feedback (RLHF) and code-mixed machine translation tasks. Given the high-cost and time-consuming preference labeling procedure, we improve this by utilizing LLMs as annotators to perform the reinforcement learning from AI feedback (RLAIF). The experiments show the effectiveness of the proposed method.

The Reopening of Pandora's Box: Analyzing the Role of LLMs in the Evolving Battle Against AI-Generated Fake News

With the rise of AI-generated content spewed at scale from large language models (LLMs), genuine concerns about the spread of fake news have intensified. The perceived ability of LLMs to produce convincing fake news at scale poses new challenges for both human and automated fake news detection systems. To address this gap, this work presents the findings from a university-level competition which aimed to explore how LLMs can be used by humans to create fake news, and to assess the ability of human annotators and AI models to detect it. A total of 110 participants used LLMs to create 252 unique fake news stories, and 84 annotators participated in the detection tasks. Our findings indicate that LLMs are ~68% more effective at detecting real news than humans. However, for fake news detection, the performance of LLMs and humans remains comparable (~60% accuracy). Additionally, we examine the impact of visual elements (e.g., pictures) in news on the accuracy of detecting fake news stories. Finally, we also examine various strategies used by fake news creators to enhance the credibility of their AI-generated content. This work highlights the increasing complexity of detecting AI-generated fake news, particularly in collaborative human-AI settings.

Monolingual and Multilingual Misinformation Detection for Low-Resource Languages: A Comprehensive Survey

In today's global digital landscape, misinformation transcends linguistic boundaries, posing a significant challenge for moderation systems. While significant advances have been made in misinformation detection, the focus remains largely on monolingual high-resource contexts, with low-resource languages often overlooked. This survey aims to bridge that gap by providing a comprehensive overview of the current research on low-resource language misinformation detection in both monolingual and multilingual settings. We review the existing datasets, methodologies, and tools used in these domains, identifying key challenges related to: data resources, model development, cultural and linguistic context, real-world applications, and research efforts. We also examine emerging approaches, such as language-agnostic models and multi-modal techniques, while emphasizing the need for improved data collection practices, interdisciplinary collaboration, and stronger incentives for socially responsible AI research. Our findings underscore the need for robust, inclusive systems capable of addressing misinformation across diverse linguistic and cultural contexts.