BeyondCT: A deep learning model for predicting pulmonary function from chest CT scans

Abstract Background: Pulmonary function tests (PFTs) and computed tomography (CT) imaging are vital in diagnosing, managing, and monitoring lung diseases. A common issue in practice is the lack of access to recorded pulmonary functions despite available chest CT scans. Purpose: To develop and validate a deep learning algorithm for predicting pulmonary function directly from chest CT scans. Methods: The development cohort came from the Pittsburgh Lung Screening Study (PLuSS) (n=3619). The validation cohort came from the Specialized Centers of Clinically Oriented Research (SCCOR) in COPD (n=662). A deep learning model called BeyondCT, combining a three-dimensional (3D) convolutional neural network (CNN) and Vision Transformer (ViT) architecture, was used to predict forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) from non-contrasted inspiratory chest CT scans. A 3D CNN model without ViT was used for comparison. Subject demographics (age, gender, smoking status) were also incorporated into the model. Performance was compared to actual PFTs using mean absolute error (MAE, L), percentage error, and R square. Results: The 3D-CNN model achieved MAEs of 0.395 L and 0.383 L, percentage errors of 13.84% and 18.85%, and R square of 0.665 and 0.679 for FVC and FEV1, respectively. The BeyondCT model without demographics had MAEs of 0.362 L and 0.371 L, percentage errors of 10.89% and 14.96%, and R square of 0.719 and 0.727, respectively. Including demographics improved performance (p<0.05), with MAEs of 0.356 L and 0.353 L, percentage errors of 10.79% and 14.82%, and R square of 0.77 and 0.739 for FVC and FEV1 in the test set. Conclusion: The BeyondCT model showed robust performance in predicting lung function from non-contrast inspiratory chest CT scans.

PMG : Personalized Multimodal Generation with Large Language Models

The emergence of large language models (LLMs) has revolutionized the capabilities of text comprehension and generation. Multi-modal generation attracts great attention from both the industry and academia, but there is little work on personalized generation, which has important applications such as recommender systems. This paper proposes the first method for personalized multimodal generation using LLMs, showcases its applications and validates its performance via an extensive experimental study on two datasets. The proposed method, Personalized Multimodal Generation (PMG for short) first converts user behaviors (e.g., clicks in recommender systems or conversations with a virtual assistant) into natural language to facilitate LLM understanding and extract user preference descriptions. Such user preferences are then fed into a generator, such as a multimodal LLM or diffusion model, to produce personalized content. To capture user preferences comprehensively and accurately, we propose to let the LLM output a combination of explicit keywords and implicit embeddings to represent user preferences. Then the combination of keywords and embeddings are used as prompts to condition the generator. We optimize a weighted sum of the accuracy and preference scores so that the generated content has a good balance between them. Compared to a baseline method without personalization, PMG has a significant improvement on personalization for up to 8% in terms of LPIPS while retaining the accuracy of generation.

IndiVec: An Exploration of Leveraging Large Language Models for Media Bias Detection with Fine-Grained Bias Indicators

This study focuses on media bias detection, crucial in today's era of influential social media platforms shaping individual attitudes and opinions. In contrast to prior work that primarily relies on training specific models tailored to particular datasets, resulting in limited adaptability and subpar performance on out-of-domain data, we introduce a general bias detection framework, IndiVec, built upon large language models. IndiVec begins by constructing a fine-grained media bias database, leveraging the robust instruction-following capabilities of large language models and vector database techniques. When confronted with new input for bias detection, our framework automatically selects the most relevant indicator from the vector database and employs majority voting to determine the input's bias label. IndiVec excels compared to previous methods due to its adaptability (demonstrating consistent performance across diverse datasets from various sources) and explainability (providing explicit top-k indicators to interpret bias predictions). Experimental results on four political bias datasets highlight IndiVec's significant superiority over baselines. Furthermore, additional experiments and analysis provide profound insights into the framework's effectiveness.

AutoAlign: Fully Automatic and Effective Knowledge Graph Alignment enabled by Large Language Models

The task of entity alignment between knowledge graphs (KGs) aims to identify every pair of entities from two different KGs that represent the same entity. Many machine learning-based methods have been proposed for this task. However, to our best knowledge, existing methods all require manually crafted seed alignments, which are expensive to obtain. In this paper, we propose the first fully automatic alignment method named AutoAlign, which does not require any manually crafted seed alignments. Specifically, for predicate embeddings, AutoAlign constructs a predicate-proximity-graph with the help of large language models to automatically capture the similarity between predicates across two KGs. For entity embeddings, AutoAlign first computes the entity embeddings of each KG independently using TransE, and then shifts the two KGs' entity embeddings into the same vector space by computing the similarity between entities based on their attributes. Thus, both predicate alignment and entity alignment can be done without manually crafted seed alignments. AutoAlign is not only fully automatic, but also highly effective. Experiments using real-world KGs show that AutoAlign improves the performance of entity alignment significantly compared to state-of-the-art methods.

A Comprehensive Survey on Deep Learning for Relation Extraction: Recent Advances and New Frontiers

Relation extraction (RE) involves identifying the relations between entities from unstructured texts. RE serves as the foundation for many natural language processing (NLP) applications, such as knowledge graph completion, question answering, and information retrieval. In recent years, deep neural networks have dominated the field of RE and made noticeable progress. Subsequently, the large pre-trained language models (PLMs) have taken the state-of-the-art of RE to a new level. This survey provides a comprehensive review of existing deep learning techniques for RE. First, we introduce RE resources, including RE datasets and evaluation metrics. Second, we propose a new taxonomy to categorize existing works from three perspectives (text representation, context encoding, and triplet prediction). Third, we discuss several important challenges faced by RE and summarize potential techniques to tackle these challenges. Finally, we outline some promising future directions and prospects in this field. This survey is expected to facilitate researchers' collaborative efforts to tackle the challenges of real-life RE systems.

TransAlign: Fully Automatic and Effective Entity Alignment for Knowledge Graphs

The task of entity alignment between knowledge graphs (KGs) aims to identify every pair of entities from two different KGs that represent the same entity. Many machine learning-based methods have been proposed for this task. However, to our best knowledge, existing methods all require manually crafted seed alignments, which are expensive to obtain. In this paper, we propose the first fully automatic alignment method named TransAlign, which does not require any manually crafted seed alignments. Specifically, for predicate embeddings, TransAlign constructs a predicate-proximity-graph to automatically capture the similarity between predicates across two KGs by learning the attention of entity types. For entity embeddings, TransAlign first computes the entity embeddings of each KG independently using TransE, and then shifts the two KGs' entity embeddings into the same vector space by computing the similarity between entities based on their attributes. Thus, both predicate alignment and entity alignment can be done without manually crafted seed alignments. TransAlign is not only fully automatic, but also highly effective. Experiments using real-world KGs show that TransAlign improves the accuracy of entity alignment significantly compared to state-of-the-art methods.

Enhancing Top-N Item Recommendations by Peer Collaboration

Deep neural networks (DNN) have achieved great success in the recommender systems (RS) domain. However, to achieve remarkable performance, DNN-based recommender models often require numerous parameters, which inevitably bring redundant neurons and weights, a phenomenon referred to as over-parameterization. In this paper, we plan to exploit such redundancy phenomena to improve the performance of RS. Specifically, we propose PCRec, a top-N item \underline{rec}ommendation framework that leverages collaborative training of two DNN-based recommender models with the same network structure, termed \underline{p}eer \underline{c}ollaboration. PCRec can reactivate and strengthen the unimportant (redundant) weights during training, which achieves higher prediction accuracy but maintains its original inference efficiency. To realize this, we first introduce two criteria to identify the importance of weights of a given recommender model. Then, we rejuvenate the unimportant weights by transplanting outside information (i.e., weights) from its peer network. After such an operation and retraining, the original recommender model is endowed with more representation capacity by possessing more functional model parameters. To show its generality, we instantiate PCRec by using three well-known recommender models. We conduct extensive experiments on three real-world datasets, and show that PCRec yields significantly better recommendations than its counterpart with the same model (parameter) size.