Learning to Efficiently Adapt Foundation Models for Self-Supervised Endoscopic 3D Scene Reconstruction from Any Cameras

Accurate 3D scene reconstruction is essential for numerous medical tasks. Given the challenges in obtaining ground truth data, there has been an increasing focus on self-supervised learning (SSL) for endoscopic depth estimation as a basis for scene reconstruction. While foundation models have shown remarkable progress in visual tasks, their direct application to the medical domain often leads to suboptimal results. However, the visual features from these models can still enhance endoscopic tasks, emphasizing the need for efficient adaptation strategies, which still lack exploration currently. In this paper, we introduce Endo3DAC, a unified framework for endoscopic scene reconstruction that efficiently adapts foundation models. We design an integrated network capable of simultaneously estimating depth maps, relative poses, and camera intrinsic parameters. By freezing the backbone foundation model and training only the specially designed Gated Dynamic Vector-Based Low-Rank Adaptation (GDV-LoRA) with separate decoder heads, Endo3DAC achieves superior depth and pose estimation while maintaining training efficiency. Additionally, we propose a 3D scene reconstruction pipeline that optimizes depth maps' scales, shifts, and a few parameters based on our integrated network. Extensive experiments across four endoscopic datasets demonstrate that Endo3DAC significantly outperforms other state-of-the-art methods while requiring fewer trainable parameters. To our knowledge, we are the first to utilize a single network that only requires surgical videos to perform both SSL depth estimation and scene reconstruction tasks. The code will be released upon acceptance.

MAP: Evaluation and Multi-Agent Enhancement of Large Language Models for Inpatient Pathways

Inpatient pathways demand complex clinical decision-making based on comprehensive patient information, posing critical challenges for clinicians. Despite advancements in large language models (LLMs) in medical applications, limited research focused on artificial intelligence (AI) inpatient pathways systems, due to the lack of large-scale inpatient datasets. Moreover, existing medical benchmarks typically concentrated on medical question-answering and examinations, ignoring the multifaceted nature of clinical decision-making in inpatient settings. To address these gaps, we first developed the Inpatient Pathway Decision Support (IPDS) benchmark from the MIMIC-IV database, encompassing 51,274 cases across nine triage departments and 17 major disease categories alongside 16 standardized treatment options. Then, we proposed the Multi-Agent Inpatient Pathways (MAP) framework to accomplish inpatient pathways with three clinical agents, including a triage agent managing the patient admission, a diagnosis agent serving as the primary decision maker at the department, and a treatment agent providing treatment plans. Additionally, our MAP framework includes a chief agent overseeing the inpatient pathways to guide and promote these three clinician agents. Extensive experiments showed our MAP improved the diagnosis accuracy by 25.10% compared to the state-of-the-art LLM HuatuoGPT2-13B. It is worth noting that our MAP demonstrated significant clinical compliance, outperforming three board-certified clinicians by 10%-12%, establishing a foundation for inpatient pathways systems.

TAIJI: Textual Anchoring for Immunizing Jailbreak Images in Vision Language Models

Vision Language Models (VLMs) have demonstrated impressive inference capabilities, but remain vulnerable to jailbreak attacks that can induce harmful or unethical responses. Existing defence methods are predominantly white-box approaches that require access to model parameters and extensive modifications, making them costly and impractical for many real-world scenarios. Although some black-box defences have been proposed, they often impose input constraints or require multiple queries, limiting their effectiveness in safety-critical tasks such as autonomous driving. To address these challenges, we propose a novel black-box defence framework called \textbf{T}extual \textbf{A}nchoring for \textbf{I}mmunizing \textbf{J}ailbreak \textbf{I}mages (\textbf{TAIJI}). TAIJI leverages key phrase-based textual anchoring to enhance the model's ability to assess and mitigate the harmful content embedded within both visual and textual prompts. Unlike existing methods, TAIJI operates effectively with a single query during inference, while preserving the VLM's performance on benign tasks. Extensive experiments demonstrate that TAIJI significantly enhances the safety and reliability of VLMs, providing a practical and efficient solution for real-world deployment.

Iterative Prompt Relocation for Distribution-Adaptive Visual Prompt Tuning

Visual prompt tuning (VPT) provides an efficient and effective solution for adapting pre-trained models to various downstream tasks by incorporating learnable prompts. However, most prior art indiscriminately applies a fixed prompt distribution across different tasks, neglecting the importance of each block differing depending on the task. In this paper, we investigate adaptive distribution optimization (ADO) by addressing two key questions: (1) How to appropriately and formally define ADO, and (2) How to design an adaptive distribution strategy guided by this definition? Through in-depth analysis, we provide an affirmative answer that properly adjusting the distribution significantly improves VPT performance, and further uncover a key insight that a nested relationship exists between ADO and VPT. Based on these findings, we propose a new VPT framework, termed PRO-VPT (iterative Prompt RelOcation-based VPT), which adaptively adjusts the distribution building upon a nested optimization formulation. Specifically, we develop a prompt relocation strategy for ADO derived from this formulation, comprising two optimization steps: identifying and pruning idle prompts, followed by determining the optimal blocks for their relocation. By iteratively performing prompt relocation and VPT, our proposal adaptively learns the optimal prompt distribution, thereby unlocking the full potential of VPT. Extensive experiments demonstrate that our proposal significantly outperforms state-of-the-art VPT methods, e.g., PRO-VPT surpasses VPT by 1.6% average accuracy, leading prompt-based methods to state-of-the-art performance on the VTAB-1k benchmark. The code is available at https://github.com/ckshang/PRO-VPT.

GenAI for Simulation Model in Model-Based Systems Engineering

Generative AI (GenAI) has demonstrated remarkable capabilities in code generation, and its integration into complex product modeling and simulation code generation can significantly enhance the efficiency of the system design phase in Model-Based Systems Engineering (MBSE). In this study, we introduce a generative system design methodology framework for MBSE, offering a practical approach for the intelligent generation of simulation models for system physical properties. First, we employ inference techniques, generative models, and integrated modeling and simulation languages to construct simulation models for system physical properties based on product design documents. Subsequently, we fine-tune the language model used for simulation model generation on an existing library of simulation models and additional datasets generated through generative modeling. Finally, we introduce evaluation metrics for the generated simulation models for system physical properties. Our proposed approach to simulation model generation presents the innovative concept of scalable templates for simulation models. Using these templates, GenAI generates simulation models for system physical properties through code completion. The experimental results demonstrate that, for mainstream open-source Transformer-based models, the quality of the simulation model is significantly improved using the simulation model generation method proposed in this paper.

Separated Contrastive Learning for Matching in Cross-domain Recommendation with Curriculum Scheduling

Cross-domain recommendation (CDR) is a task that aims to improve the recommendation performance in a target domain by leveraging the information from source domains. Contrastive learning methods have been widely adopted among intra-domain (intra-CL) and inter-domain (inter-CL) users/items for their representation learning and knowledge transfer during the matching stage of CDR. However, we observe that directly employing contrastive learning on mixed-up intra-CL and inter-CL tasks ignores the difficulty of learning from inter-domain over learning from intra-domain, and thus could cause severe training instability. Therefore, this instability deteriorates the representation learning process and hurts the quality of generated embeddings. To this end, we propose a novel framework named SCCDR built up on a separated intra-CL and inter-CL paradigm and a stop-gradient operation to handle the drawback. Specifically, SCCDR comprises two specialized curriculum stages: intra-inter separation and inter-domain curriculum scheduling. The former stage explicitly uses two distinct contrastive views for the intra-CL task in the source and target domains, respectively. Meanwhile, the latter stage deliberately tackles the inter-CL tasks with a curriculum scheduling strategy that derives effective curricula by accounting for the difficulty of negative samples anchored by overlapping users. Empirical experiments on various open-source datasets and an offline proprietary industrial dataset extracted from a real-world recommender system, and an online A/B test verify that SCCDR achieves state-of-the-art performance over multiple baselines.

Long-tailed Medical Diagnosis with Relation-aware Representation Learning and Iterative Classifier Calibration

Recently computer-aided diagnosis has demonstrated promising performance, effectively alleviating the workload of clinicians. However, the inherent sample imbalance among different diseases leads algorithms biased to the majority categories, leading to poor performance for rare categories. Existing works formulated this challenge as a long-tailed problem and attempted to tackle it by decoupling the feature representation and classification. Yet, due to the imbalanced distribution and limited samples from tail classes, these works are prone to biased representation learning and insufficient classifier calibration. To tackle these problems, we propose a new Long-tailed Medical Diagnosis (LMD) framework for balanced medical image classification on long-tailed datasets. In the initial stage, we develop a Relation-aware Representation Learning (RRL) scheme to boost the representation ability by encouraging the encoder to capture intrinsic semantic features through different data augmentations. In the subsequent stage, we propose an Iterative Classifier Calibration (ICC) scheme to calibrate the classifier iteratively. This is achieved by generating a large number of balanced virtual features and fine-tuning the encoder using an Expectation-Maximization manner. The proposed ICC compensates for minority categories to facilitate unbiased classifier optimization while maintaining the diagnostic knowledge in majority classes. Comprehensive experiments on three public long-tailed medical datasets demonstrate that our LMD framework significantly surpasses state-of-the-art approaches. The source code can be accessed at https://github.com/peterlipan/LMD.

UNIP: Rethinking Pre-trained Attention Patterns for Infrared Semantic Segmentation

Pre-training techniques significantly enhance the performance of semantic segmentation tasks with limited training data. However, the efficacy under a large domain gap between pre-training (e.g. RGB) and fine-tuning (e.g. infrared) remains underexplored. In this study, we first benchmark the infrared semantic segmentation performance of various pre-training methods and reveal several phenomena distinct from the RGB domain. Next, our layerwise analysis of pre-trained attention maps uncovers that: (1) There are three typical attention patterns (local, hybrid, and global); (2) Pre-training tasks notably influence the pattern distribution across layers; (3) The hybrid pattern is crucial for semantic segmentation as it attends to both nearby and foreground elements; (4) The texture bias impedes model generalization in infrared tasks. Building on these insights, we propose UNIP, a UNified Infrared Pre-training framework, to enhance the pre-trained model performance. This framework uses the hybrid-attention distillation NMI-HAD as the pre-training target, a large-scale mixed dataset InfMix for pre-training, and a last-layer feature pyramid network LL-FPN for fine-tuning. Experimental results show that UNIP outperforms various pre-training methods by up to 13.5\% in average mIoU on three infrared segmentation tasks, evaluated using fine-tuning and linear probing metrics. UNIP-S achieves performance on par with MAE-L while requiring only 1/10 of the computational cost. Furthermore, UNIP significantly surpasses state-of-the-art (SOTA) infrared or RGB segmentation methods and demonstrates broad potential for application in other modalities, such as RGB and depth. Our code is available at https://github.com/casiatao/UNIP.

Advancing Dense Endoscopic Reconstruction with Gaussian Splatting-driven Surface Normal-aware Tracking and Mapping

Simultaneous Localization and Mapping (SLAM) is essential for precise surgical interventions and robotic tasks in minimally invasive procedures. While recent advancements in 3D Gaussian Splatting (3DGS) have improved SLAM with high-quality novel view synthesis and fast rendering, these systems struggle with accurate depth and surface reconstruction due to multi-view inconsistencies. Simply incorporating SLAM and 3DGS leads to mismatches between the reconstructed frames. In this work, we present Endo-2DTAM, a real-time endoscopic SLAM system with 2D Gaussian Splatting (2DGS) to address these challenges. Endo-2DTAM incorporates a surface normal-aware pipeline, which consists of tracking, mapping, and bundle adjustment modules for geometrically accurate reconstruction. Our robust tracking module combines point-to-point and point-to-plane distance metrics, while the mapping module utilizes normal consistency and depth distortion to enhance surface reconstruction quality. We also introduce a pose-consistent strategy for efficient and geometrically coherent keyframe sampling. Extensive experiments on public endoscopic datasets demonstrate that Endo-2DTAM achieves an RMSE of $1.87\pm 0.63$ mm for depth reconstruction of surgical scenes while maintaining computationally efficient tracking, high-quality visual appearance, and real-time rendering. Our code will be released at github.com/lastbasket/Endo-2DTAM.

Semantic Consistency Regularization with Large Language Models for Semi-supervised Sentiment Analysis

Accurate sentiment analysis of texts is crucial for a variety of applications, such as understanding customer feedback, monitoring market trends, and detecting public sentiment. However, manually annotating large sentiment corpora for supervised learning is labor-intensive and time-consuming. Therefore, it is essential and effective to develop a semi-supervised method for the sentiment analysis task. Although some methods have been proposed for semi-supervised text classification, they rely on the intrinsic information within the unlabeled data and the learning capability of the NLP model, which lack generalization ability to the sentiment analysis scenario and may prone to overfit. Inspired by the ability of pretrained Large Language Models (LLMs) in following instructions and generating coherent text, we propose a Semantic Consistency Regularization with Large Language Models (SCR) framework for semi-supervised sentiment analysis. We introduce two prompting strategies to semantically enhance unlabeled text using LLMs. The first is Entity-based Enhancement (SCR-EE), which involves extracting entities and numerical information, and querying the LLM to reconstruct the textual information. The second is Concept-based Enhancement (SCR-CE), which directly queries the LLM with the original sentence for semantic reconstruction. Subsequently, the LLM-augmented data is utilized for a consistency loss with confidence thresholding, which preserves high-quality agreement samples to provide additional supervision signals during training. Furthermore, to fully utilize the uncertain unlabeled data samples, we propose a class re-assembling strategy inspired by the class space shrinking theorem. Experiments show our method achieves remarkable performance over prior semi-supervised methods.