CFFormer: Cross CNN-Transformer Channel Attention and Spatial Feature Fusion for Improved Segmentation of Low Quality Medical Images

Hybrid CNN-Transformer models are designed to combine the advantages of Convolutional Neural Networks (CNNs) and Transformers to efficiently model both local information and long-range dependencies. However, most research tends to focus on integrating the spatial features of CNNs and Transformers, while overlooking the critical importance of channel features. This is particularly significant for model performance in low-quality medical image segmentation. Effective channel feature extraction can significantly enhance the model's ability to capture contextual information and improve its representation capabilities. To address this issue, we propose a hybrid CNN-Transformer model, CFFormer, and introduce two modules: the Cross Feature Channel Attention (CFCA) module and the X-Spatial Feature Fusion (XFF) module. The model incorporates dual encoders, with the CNN encoder focusing on capturing local features and the Transformer encoder modeling global features. The CFCA module filters and facilitates interactions between the channel features from the two encoders, while the XFF module effectively reduces the significant semantic information differences in spatial features, enabling a smooth and cohesive spatial feature fusion. We evaluate our model across eight datasets covering five modalities to test its generalization capability. Experimental results demonstrate that our model outperforms current state-of-the-art (SOTA) methods, with particularly superior performance on datasets characterized by blurry boundaries and low contrast.

WSI-LLaVA: A Multimodal Large Language Model for Whole Slide Image

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to bypass crucial morphological features that pathologists rely on for diagnosis. To address these challenges, we first introduce WSI-Bench, a large-scale morphology-aware benchmark containing 180k VQA pairs from 9,850 WSIs across 30 cancer types, designed to evaluate MLLMs' understanding of morphological characteristics crucial for accurate diagnosis. Building upon this benchmark, we present WSI-LLaVA, a novel framework for gigapixel WSI understanding that employs a three-stage training approach: WSI-text alignment, feature space alignment, and task-specific instruction tuning. To better assess model performance in pathological contexts, we develop two specialized WSI metrics: WSI-Precision and WSI-Relevance. Experimental results demonstrate that WSI-LLaVA outperforms existing models across all capability dimensions, with a significant improvement in morphological analysis, establishing a clear correlation between morphological understanding and diagnostic accuracy.

TAVP: Task-Adaptive Visual Prompt for Cross-domain Few-shot Segmentation

Under the backdrop of large-scale pre-training, large visual models (LVM) have demonstrated significant potential in image understanding. The recent emergence of the Segment Anything Model (SAM) has brought a qualitative shift in the field of image segmentation, supporting flexible interactive cues and strong learning capabilities. However, its performance often falls short in cross-domain and few-shot applications. Transferring prior knowledge from foundation models to new applications while preserving learning capabilities is worth exploring. This work proposes a task-adaptive prompt framework based on SAM, a new paradigm for Cross-dominan few-shot segmentation (CD-FSS). First, a Multi-level Feature Fusion (MFF) was used for integrated feature extraction. Besides, an additional Class Domain Task-Adaptive Auto-Prompt (CDTAP) module was combined with the segmentation branch for class-domain agnostic feature extraction and high-quality learnable prompt production. This significant advancement uses a unique generative approach to prompts alongside a comprehensive model structure and specialized prototype computation. While ensuring that the prior knowledge of SAM is not discarded, the new branch disentangles category and domain information through prototypes, guiding it in adapting the CD-FSS. We have achieved the best results on three benchmarks compared to the recent state-of-the-art (SOTA) methods. Comprehensive experiments showed that after task-specific and weighted guidance, the abundant feature information of SAM can be better learned for CD-FSS.

NuSegDG: Integration of Heterogeneous Space and Gaussian Kernel for Domain-Generalized Nuclei Segmentation

Domain-generalized nuclei segmentation refers to the generalizability of models to unseen domains based on knowledge learned from source domains and is challenged by various image conditions, cell types, and stain strategies. Recently, the Segment Anything Model (SAM) has made great success in universal image segmentation by interactive prompt modes (e.g., point and box). Despite its strengths, the original SAM presents limited adaptation to medical images. Moreover, SAM requires providing manual bounding box prompts for each object to produce satisfactory segmentation masks, so it is laborious in nuclei segmentation scenarios. To address these limitations, we propose a domain-generalizable framework for nuclei image segmentation, abbreviated to NuSegDG. Specifically, we first devise a Heterogeneous Space Adapter (HS-Adapter) to learn multi-dimensional feature representations of different nuclei domains by injecting a small number of trainable parameters into the image encoder of SAM. To alleviate the labor-intensive requirement of manual prompts, we introduce a Gaussian-Kernel Prompt Encoder (GKP-Encoder) to generate density maps driven by a single point, which guides segmentation predictions by mixing position prompts and semantic prompts. Furthermore, we present a Two-Stage Mask Decoder (TSM-Decoder) to effectively convert semantic masks to instance maps without the manual demand for morphological shape refinement. Based on our experimental evaluations, the proposed NuSegDG demonstrates state-of-the-art performance in nuclei instance segmentation, exhibiting superior domain generalization capabilities. The source code is available at https://github.com/xq141839/NuSegDG.

ESP-MedSAM: Efficient Self-Prompting SAM for Universal Domain-Generalized Medical Image Segmentation

The Segment Anything Model (SAM) has demonstrated outstanding adaptation to medical image segmentation but still faces three major challenges. Firstly, the huge computational costs of SAM limit its real-world applicability. Secondly, SAM depends on manual annotations (e.g., points, boxes) as prompts, which are laborious and impractical in clinical scenarios. Thirdly, SAM handles all segmentation targets equally, which is suboptimal for diverse medical modalities with inherent heterogeneity. To address these issues, we propose an Efficient Self-Prompting SAM for universal medical image segmentation, named ESP-MedSAM. We devise a Multi-Modal Decoupled Knowledge Distillation (MMDKD) strategy to distil common image knowledge and domain-specific medical knowledge from the foundation model to train a lightweight image encoder and a modality controller. Further, they combine with the additionally introduced Self-Patch Prompt Generator (SPPG) and Query-Decoupled Modality Decoder (QDMD) to construct ESP-MedSAM. Specifically, SPPG aims to generate a set of patch prompts automatically and QDMD leverages a one-to-one strategy to provide an independent decoding channel for every modality. Extensive experiments indicate that ESP-MedSAM outperforms state-of-the-arts in diverse medical imaging segmentation takes, displaying superior zero-shot learning and modality transfer ability. Especially, our framework uses only 31.4% parameters compared to SAM-Base.

Millimeter Wave Radar-based Human Activity Recognition for Healthcare Monitoring Robot

Healthcare monitoring is crucial, especially for the daily care of elderly individuals living alone. It can detect dangerous occurrences, such as falls, and provide timely alerts to save lives. Non-invasive millimeter wave (mmWave) radar-based healthcare monitoring systems using advanced human activity recognition (HAR) models have recently gained significant attention. However, they encounter challenges in handling sparse point clouds, achieving real-time continuous classification, and coping with limited monitoring ranges when statically mounted. To overcome these limitations, we propose RobHAR, a movable robot-mounted mmWave radar system with lightweight deep neural networks for real-time monitoring of human activities. Specifically, we first propose a sparse point cloud-based global embedding to learn the features of point clouds using the light-PointNet (LPN) backbone. Then, we learn the temporal pattern with a bidirectional lightweight LSTM model (BiLiLSTM). In addition, we implement a transition optimization strategy, integrating the Hidden Markov Model (HMM) with Connectionist Temporal Classification (CTC) to improve the accuracy and robustness of the continuous HAR. Our experiments on three datasets indicate that our method significantly outperforms the previous studies in both discrete and continuous HAR tasks. Finally, we deploy our system on a movable robot-mounted edge computing platform, achieving flexible healthcare monitoring in real-world scenarios.

ESP-Zero: Unsupervised enhancement of zero-shot classification for Extremely Sparse Point cloud

In recent years, zero-shot learning has attracted the focus of many researchers, due to its flexibility and generality. Many approaches have been proposed to achieve the zero-shot classification of the point clouds for 3D object understanding, following the schema of CLIP. However, in the real world, the point clouds could be extremely sparse, dramatically limiting the effectiveness of the 3D point cloud encoders, and resulting in the misalignment of point cloud features and text embeddings. To the point cloud encoders to fit the extremely sparse point clouds without re-running the pre-training procedure which could be time-consuming and expensive, in this work, we propose an unsupervised model adaptation approach to enhance the point cloud encoder for the extremely sparse point clouds. We propose a novel fused-cross attention layer that expands the pre-trained self-attention layer with additional learnable tokens and attention blocks, which effectively modifies the point cloud features while maintaining the alignment between point cloud features and text embeddings. We also propose a complementary learning-based self-distillation schema that encourages the modified features to be pulled apart from the irrelevant text embeddings without overfitting the feature space to the observed text embeddings. Extensive experiments demonstrate that the proposed approach effectively increases the zero-shot capability on extremely sparse point clouds, and overwhelms other state-of-the-art model adaptation approaches.

MorphText: Deep Morphology Regularized Arbitrary-shape Scene Text Detection

Bottom-up text detection methods play an important role in arbitrary-shape scene text detection but there are two restrictions preventing them from achieving their great potential, i.e., 1) the accumulation of false text segment detections, which affects subsequent processing, and 2) the difficulty of building reliable connections between text segments. Targeting these two problems, we propose a novel approach, named ``MorphText", to capture the regularity of texts by embedding deep morphology for arbitrary-shape text detection. Towards this end, two deep morphological modules are designed to regularize text segments and determine the linkage between them. First, a Deep Morphological Opening (DMOP) module is constructed to remove false text segment detections generated in the feature extraction process. Then, a Deep Morphological Closing (DMCL) module is proposed to allow text instances of various shapes to stretch their morphology along their most significant orientation while deriving their connections. Extensive experiments conducted on four challenging benchmark datasets (CTW1500, Total-Text, MSRA-TD500 and ICDAR2017) demonstrate that our proposed MorphText outperforms both top-down and bottom-up state-of-the-art arbitrary-shape scene text detection approaches.

Scale Optimization Using Evolutionary Reinforcement Learning for Object Detection on Drone Imagery

Object detection in aerial imagery presents a significant challenge due to large scale variations among objects. This paper proposes an evolutionary reinforcement learning agent, integrated within a coarse-to-fine object detection framework, to optimize the scale for more effective detection of objects in such images. Specifically, a set of patches potentially containing objects are first generated. A set of rewards measuring the localization accuracy, the accuracy of predicted labels, and the scale consistency among nearby patches are designed in the agent to guide the scale optimization. The proposed scale-consistency reward ensures similar scales for neighboring objects of the same category. Furthermore, a spatial-semantic attention mechanism is designed to exploit the spatial semantic relations between patches. The agent employs the proximal policy optimization strategy in conjunction with the evolutionary strategy, effectively utilizing both the current patch status and historical experience embedded in the agent. The proposed model is compared with state-of-the-art methods on two benchmark datasets for object detection on drone imagery. It significantly outperforms all the compared methods.

Point Clouds Are Specialized Images: A Knowledge Transfer Approach for 3D Understanding

Self-supervised representation learning (SSRL) has gained increasing attention in point cloud understanding, in addressing the challenges posed by 3D data scarcity and high annotation costs. This paper presents PCExpert, a novel SSRL approach that reinterprets point clouds as "specialized images". This conceptual shift allows PCExpert to leverage knowledge derived from large-scale image modality in a more direct and deeper manner, via extensively sharing the parameters with a pre-trained image encoder in a multi-way Transformer architecture. The parameter sharing strategy, combined with a novel pretext task for pre-training, i.e., transformation estimation, empowers PCExpert to outperform the state of the arts in a variety of tasks, with a remarkable reduction in the number of trainable parameters. Notably, PCExpert's performance under LINEAR fine-tuning (e.g., yielding a 90.02% overall accuracy on ScanObjectNN) has already approached the results obtained with FULL model fine-tuning (92.66%), demonstrating its effective and robust representation capability.