WSI-LLaVA: A Multimodal Large Language Model for Whole Slide Image

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to bypass crucial morphological features that pathologists rely on for diagnosis. To address these challenges, we first introduce WSI-Bench, a large-scale morphology-aware benchmark containing 180k VQA pairs from 9,850 WSIs across 30 cancer types, designed to evaluate MLLMs' understanding of morphological characteristics crucial for accurate diagnosis. Building upon this benchmark, we present WSI-LLaVA, a novel framework for gigapixel WSI understanding that employs a three-stage training approach: WSI-text alignment, feature space alignment, and task-specific instruction tuning. To better assess model performance in pathological contexts, we develop two specialized WSI metrics: WSI-Precision and WSI-Relevance. Experimental results demonstrate that WSI-LLaVA outperforms existing models across all capability dimensions, with a significant improvement in morphological analysis, establishing a clear correlation between morphological understanding and diagnostic accuracy.

Medchain: Bridging the Gap Between LLM Agents and Clinical Practice through Interactive Sequential Benchmarking

Clinical decision making (CDM) is a complex, dynamic process crucial to healthcare delivery, yet it remains a significant challenge for artificial intelligence systems. While Large Language Model (LLM)-based agents have been tested on general medical knowledge using licensing exams and knowledge question-answering tasks, their performance in the CDM in real-world scenarios is limited due to the lack of comprehensive testing datasets that mirror actual medical practice. To address this gap, we present MedChain, a dataset of 12,163 clinical cases that covers five key stages of clinical workflow. MedChain distinguishes itself from existing benchmarks with three key features of real-world clinical practice: personalization, interactivity, and sequentiality. Further, to tackle real-world CDM challenges, we also propose MedChain-Agent, an AI system that integrates a feedback mechanism and a MCase-RAG module to learn from previous cases and adapt its responses. MedChain-Agent demonstrates remarkable adaptability in gathering information dynamically and handling sequential clinical tasks, significantly outperforming existing approaches. The relevant dataset and code will be released upon acceptance of this paper.

HairDiffusion: Vivid Multi-Colored Hair Editing via Latent Diffusion

Hair editing is a critical image synthesis task that aims to edit hair color and hairstyle using text descriptions or reference images, while preserving irrelevant attributes (e.g., identity, background, cloth). Many existing methods are based on StyleGAN to address this task. However, due to the limited spatial distribution of StyleGAN, it struggles with multiple hair color editing and facial preservation. Considering the advancements in diffusion models, we utilize Latent Diffusion Models (LDMs) for hairstyle editing. Our approach introduces Multi-stage Hairstyle Blend (MHB), effectively separating control of hair color and hairstyle in diffusion latent space. Additionally, we train a warping module to align the hair color with the target region. To further enhance multi-color hairstyle editing, we fine-tuned a CLIP model using a multi-color hairstyle dataset. Our method not only tackles the complexity of multi-color hairstyles but also addresses the challenge of preserving original colors during diffusion editing. Extensive experiments showcase the superiority of our method in editing multi-color hairstyles while preserving facial attributes given textual descriptions and reference images.

Towards Combating Frequency Simplicity-biased Learning for Domain Generalization

Domain generalization methods aim to learn transferable knowledge from source domains that can generalize well to unseen target domains. Recent studies show that neural networks frequently suffer from a simplicity-biased learning behavior which leads to over-reliance on specific frequency sets, namely as frequency shortcuts, instead of semantic information, resulting in poor generalization performance. Despite previous data augmentation techniques successfully enhancing generalization performances, they intend to apply more frequency shortcuts, thereby causing hallucinations of generalization improvement. In this paper, we aim to prevent such learning behavior of applying frequency shortcuts from a data-driven perspective. Given the theoretical justification of models' biased learning behavior on different spatial frequency components, which is based on the dataset frequency properties, we argue that the learning behavior on various frequency components could be manipulated by changing the dataset statistical structure in the Fourier domain. Intuitively, as frequency shortcuts are hidden in the dominant and highly dependent frequencies of dataset structure, dynamically perturbating the over-reliance frequency components could prevent the application of frequency shortcuts. To this end, we propose two effective data augmentation modules designed to collaboratively and adaptively adjust the frequency characteristic of the dataset, aiming to dynamically influence the learning behavior of the model and ultimately serving as a strategy to mitigate shortcut learning. Code is available at AdvFrequency (https://github.com/C0notSilly/AdvFrequency).

SynFER: Towards Boosting Facial Expression Recognition with Synthetic Data

Facial expression datasets remain limited in scale due to privacy concerns, the subjectivity of annotations, and the labor-intensive nature of data collection. This limitation poses a significant challenge for developing modern deep learning-based facial expression analysis models, particularly foundation models, that rely on large-scale data for optimal performance. To tackle the overarching and complex challenge, we introduce SynFER (Synthesis of Facial Expressions with Refined Control), a novel framework for synthesizing facial expression image data based on high-level textual descriptions as well as more fine-grained and precise control through facial action units. To ensure the quality and reliability of the synthetic data, we propose a semantic guidance technique to steer the generation process and a pseudo-label generator to help rectify the facial expression labels for the synthetic images. To demonstrate the generation fidelity and the effectiveness of the synthetic data from SynFER, we conduct extensive experiments on representation learning using both synthetic data and real-world data. Experiment results validate the efficacy of the proposed approach and the synthetic data. Notably, our approach achieves a 67.23% classification accuracy on AffectNet when training solely with synthetic data equivalent to the AffectNet training set size, which increases to 69.84% when scaling up to five times the original size. Our code will be made publicly available.

Low-Light Enhancement Effect on Classification and Detection: An Empirical Study

Low-light images are commonly encountered in real-world scenarios, and numerous low-light image enhancement (LLIE) methods have been proposed to improve the visibility of these images. The primary goal of LLIE is to generate clearer images that are more visually pleasing to humans. However, the impact of LLIE methods in high-level vision tasks, such as image classification and object detection, which rely on high-quality image datasets, is not well {explored}. To explore the impact, we comprehensively evaluate LLIE methods on these high-level vision tasks by utilizing an empirical investigation comprising image classification and object detection experiments. The evaluation reveals a dichotomy: {\textit{While Low-Light Image Enhancement (LLIE) methods enhance human visual interpretation, their effect on computer vision tasks is inconsistent and can sometimes be harmful. }} Our findings suggest a disconnect between image enhancement for human visual perception and for machine analysis, indicating a need for LLIE methods tailored to support high-level vision tasks effectively. This insight is crucial for the development of LLIE techniques that align with the needs of both human and machine vision.

SFDA-rPPG: Source-Free Domain Adaptive Remote Physiological Measurement with Spatio-Temporal Consistency

Remote Photoplethysmography (rPPG) is a non-contact method that uses facial video to predict changes in blood volume, enabling physiological metrics measurement. Traditional rPPG models often struggle with poor generalization capacity in unseen domains. Current solutions to this problem is to improve its generalization in the target domain through Domain Generalization (DG) or Domain Adaptation (DA). However, both traditional methods require access to both source domain data and target domain data, which cannot be implemented in scenarios with limited access to source data, and another issue is the privacy of accessing source domain data. In this paper, we propose the first Source-free Domain Adaptation benchmark for rPPG measurement (SFDA-rPPG), which overcomes these limitations by enabling effective domain adaptation without access to source domain data. Our framework incorporates a Three-Branch Spatio-Temporal Consistency Network (TSTC-Net) to enhance feature consistency across domains. Furthermore, we propose a new rPPG distribution alignment loss based on the Frequency-domain Wasserstein Distance (FWD), which leverages optimal transport to align power spectrum distributions across domains effectively and further enforces the alignment of the three branches. Extensive cross-domain experiments and ablation studies demonstrate the effectiveness of our proposed method in source-free domain adaptation settings. Our findings highlight the significant contribution of the proposed FWD loss for distributional alignment, providing a valuable reference for future research and applications. The source code is available at https://github.com/XieYiping66/SFDA-rPPG

MFCLIP: Multi-modal Fine-grained CLIP for Generalizable Diffusion Face Forgery Detection

The rapid development of photo-realistic face generation methods has raised significant concerns in society and academia, highlighting the urgent need for robust and generalizable face forgery detection (FFD) techniques. Although existing approaches mainly capture face forgery patterns using image modality, other modalities like fine-grained noises and texts are not fully explored, which limits the generalization capability of the model. In addition, most FFD methods tend to identify facial images generated by GAN, but struggle to detect unseen diffusion-synthesized ones. To address the limitations, we aim to leverage the cutting-edge foundation model, contrastive language-image pre-training (CLIP), to achieve generalizable diffusion face forgery detection (DFFD). In this paper, we propose a novel multi-modal fine-grained CLIP (MFCLIP) model, which mines comprehensive and fine-grained forgery traces across image-noise modalities via language-guided face forgery representation learning, to facilitate the advancement of DFFD. Specifically, we devise a fine-grained language encoder (FLE) that extracts fine global language features from hierarchical text prompts. We design a multi-modal vision encoder (MVE) to capture global image forgery embeddings as well as fine-grained noise forgery patterns extracted from the richest patch, and integrate them to mine general visual forgery traces. Moreover, we build an innovative plug-and-play sample pair attention (SPA) method to emphasize relevant negative pairs and suppress irrelevant ones, allowing cross-modality sample pairs to conduct more flexible alignment. Extensive experiments and visualizations show that our model outperforms the state of the arts on different settings like cross-generator, cross-forgery, and cross-dataset evaluations.

TAVP: Task-Adaptive Visual Prompt for Cross-domain Few-shot Segmentation

Under the backdrop of large-scale pre-training, large visual models (LVM) have demonstrated significant potential in image understanding. The recent emergence of the Segment Anything Model (SAM) has brought a qualitative shift in the field of image segmentation, supporting flexible interactive cues and strong learning capabilities. However, its performance often falls short in cross-domain and few-shot applications. Transferring prior knowledge from foundation models to new applications while preserving learning capabilities is worth exploring. This work proposes a task-adaptive prompt framework based on SAM, a new paradigm for Cross-dominan few-shot segmentation (CD-FSS). First, a Multi-level Feature Fusion (MFF) was used for integrated feature extraction. Besides, an additional Class Domain Task-Adaptive Auto-Prompt (CDTAP) module was combined with the segmentation branch for class-domain agnostic feature extraction and high-quality learnable prompt production. This significant advancement uses a unique generative approach to prompts alongside a comprehensive model structure and specialized prototype computation. While ensuring that the prior knowledge of SAM is not discarded, the new branch disentangles category and domain information through prototypes, guiding it in adapting the CD-FSS. We have achieved the best results on three benchmarks compared to the recent state-of-the-art (SOTA) methods. Comprehensive experiments showed that after task-specific and weighted guidance, the abundant feature information of SAM can be better learned for CD-FSS.

Activation Space Selectable Kolmogorov-Arnold Networks

The multilayer perceptron (MLP), a fundamental paradigm in current artificial intelligence, is widely applied in fields such as computer vision and natural language processing. However, the recently proposed Kolmogorov-Arnold Network (KAN), based on nonlinear additive connections, has been proven to achieve performance comparable to MLPs with significantly fewer parameters. Despite this potential, the use of a single activation function space results in reduced performance of KAN and related works across different tasks. To address this issue, we propose an activation space Selectable KAN (S-KAN). S-KAN employs an adaptive strategy to choose the possible activation mode for data at each feedforward KAN node. Our approach outperforms baseline methods in seven representative function fitting tasks and significantly surpasses MLP methods with the same level of parameters. Furthermore, we extend the structure of S-KAN and propose an activation space selectable Convolutional KAN (S-ConvKAN), which achieves leading results on four general image classification datasets. Our method mitigates the performance variability of the original KAN across different tasks and demonstrates through extensive experiments that feedforward KANs with selectable activations can achieve or even exceed the performance of MLP-based methods. This work contributes to the understanding of the data-centric design of new AI paradigms and provides a foundational reference for innovations in KAN-based network architectures.