Abstract:Background: Parkinson's disease remains a major neurodegenerative disorder with high misdiagnosis rates, primarily due to reliance on clinical rating scales. Recent studies have demonstrated a strong association between gut microbiota and Parkinson's disease, suggesting that microbial composition may serve as a promising biomarker. Although deep learning models based ongut microbiota show potential for early prediction, most approaches rely on single classifiers and often overlook inter-strain correlations or temporal dynamics. Therefore, there is an urgent need for more robust feature extraction methods tailored to microbiome data. Methods: We proposed BDPM (A Machine Learning-Based Feature Extractor for Parkinson's Disease Classification via Gut Microbiota Analysis). First, we collected gut microbiota profiles from 39 Parkinson's patients and their healthy spouses to identify differentially abundant taxa. Second, we developed an innovative feature selection framework named RFRE (Random Forest combined with Recursive Feature Elimination), integrating ecological knowledge to enhance biological interpretability. Finally, we designed a hybrid classification model to capture temporal and spatial patterns in microbiome data.
Abstract:Large Language Models (LLMs) have shown impressive capabilities in natural language processing but still struggle to perform well on knowledge-intensive tasks that require deep reasoning and the integration of external knowledge. Although methods such as Retrieval-Augmented Generation (RAG) and Chain-of-Thought (CoT) have been proposed to enhance LLMs with external knowledge, they still suffer from internal bias in LLMs, which often leads to incorrect answers. In this paper, we propose a novel causal prompting framework, Conditional Front-Door Prompting (CFD-Prompting), which enables the unbiased estimation of the causal effect between the query and the answer, conditional on external knowledge, while mitigating internal bias. By constructing counterfactual external knowledge, our framework simulates how the query behaves under varying contexts, addressing the challenge that the query is fixed and is not amenable to direct causal intervention. Compared to the standard front-door adjustment, the conditional variant operates under weaker assumptions, enhancing both robustness and generalisability of the reasoning process. Extensive experiments across multiple LLMs and benchmark datasets demonstrate that CFD-Prompting significantly outperforms existing baselines in both accuracy and robustness.
Abstract:Data plays a pivotal role in the groundbreaking advancements in artificial intelligence. The quantitative analysis of data significantly contributes to model training, enhancing both the efficiency and quality of data utilization. However, existing data analysis tools often lag in accuracy. For instance, many of these tools even assume that the loss function of neural networks is convex. These limitations make it challenging to implement current methods effectively. In this paper, we introduce a new formulation to approximate a sample's influence by accumulating the differences in influence between consecutive learning steps, which we term Diff-In. Specifically, we formulate the sample-wise influence as the cumulative sum of its changes/differences across successive training iterations. By employing second-order approximations, we approximate these difference terms with high accuracy while eliminating the need for model convexity required by existing methods. Despite being a second-order method, Diff-In maintains computational complexity comparable to that of first-order methods and remains scalable. This efficiency is achieved by computing the product of the Hessian and gradient, which can be efficiently approximated using finite differences of first-order gradients. We assess the approximation accuracy of Diff-In both theoretically and empirically. Our theoretical analysis demonstrates that Diff-In achieves significantly lower approximation error compared to existing influence estimators. Extensive experiments further confirm its superior performance across multiple benchmark datasets in three data-centric tasks: data cleaning, data deletion, and coreset selection. Notably, our experiments on data pruning for large-scale vision-language pre-training show that Diff-In can scale to millions of data points and outperforms strong baselines.
Abstract:Geometry problem solving (GPS) requires models to master diagram comprehension, logical reasoning, knowledge application, numerical computation, and auxiliary line construction. This presents a significant challenge for Multimodal Large Language Models (MLLMs). However, existing benchmarks for evaluating MLLM geometry skills overlook auxiliary line construction and lack fine-grained process evaluation, making them insufficient for assessing MLLMs' long-step reasoning abilities. To bridge these gaps, we present the GeoLaux benchmark, comprising 2,186 geometry problems, incorporating both calculation and proving questions. Notably, the problems require an average of 6.51 reasoning steps, with a maximum of 24 steps, and 41.8% of them need auxiliary line construction. Building on the dataset, we design a novel five-dimensional evaluation strategy assessing answer correctness, process correctness, process quality, auxiliary line impact, and error causes. Extensive experiments on 13 leading MLLMs (including thinking models and non-thinking models) yield three pivotal findings: First, models exhibit substantial performance degradation in extended reasoning steps (nine models demonstrate over 50% performance drop). Second, compared to calculation problems, MLLMs tend to take shortcuts when solving proving problems. Third, models lack auxiliary line awareness, and enhancing this capability proves particularly beneficial for overall geometry reasoning improvement. These findings establish GeoLaux as both a benchmark for evaluating MLLMs' long-step geometric reasoning with auxiliary lines and a guide for capability advancement. Our dataset and code are included in supplementary materials and will be released.
Abstract:Harnessing the power of diffusion models to synthesize auxiliary training data based on latent space features has proven effective in enhancing out-of-distribution (OOD) detection performance. However, extracting effective features outside the in-distribution (ID) boundary in latent space remains challenging due to the difficulty of identifying decision boundaries between classes. This paper proposes a novel framework called Boundary-based Out-Of-Distribution data generation (BOOD), which synthesizes high-quality OOD features and generates human-compatible outlier images using diffusion models. BOOD first learns a text-conditioned latent feature space from the ID dataset, selects ID features closest to the decision boundary, and perturbs them to cross the decision boundary to form OOD features. These synthetic OOD features are then decoded into images in pixel space by a diffusion model. Compared to previous works, BOOD provides a more training efficient strategy for synthesizing informative OOD features, facilitating clearer distinctions between ID and OOD data. Extensive experimental results on common benchmarks demonstrate that BOOD surpasses the state-of-the-art method significantly, achieving a 29.64% decrease in average FPR95 (40.31% vs. 10.67%) and a 7.27% improvement in average AUROC (90.15% vs. 97.42%) on the CIFAR-100 dataset.
Abstract:The detection of micro-expression Action Units (AUs) is a formidable challenge in affective computing, pivotal for decoding subtle, involuntary human emotions. While Large Language Models (LLMs) demonstrate profound reasoning abilities, their application to the fine-grained, low-intensity domain of micro-expression AU detection remains unexplored. This paper pioneers this direction by introducing \textbf{AU-LLM}, a novel framework that for the first time uses LLM to detect AUs in micro-expression datasets with subtle intensities and the scarcity of data. We specifically address the critical vision-language semantic gap, the \textbf{Enhanced Fusion Projector (EFP)}. The EFP employs a Multi-Layer Perceptron (MLP) to intelligently fuse mid-level (local texture) and high-level (global semantics) visual features from a specialized 3D-CNN backbone into a single, information-dense token. This compact representation effectively empowers the LLM to perform nuanced reasoning over subtle facial muscle movements.Through extensive evaluations on the benchmark CASME II and SAMM datasets, including stringent Leave-One-Subject-Out (LOSO) and cross-domain protocols, AU-LLM establishes a new state-of-the-art, validating the significant potential and robustness of LLM-based reasoning for micro-expression analysis. The codes are available at https://github.com/ZS-liu-JLU/AU-LLMs.
Abstract:We present Megrez2, a novel lightweight and high-performance language model architecture optimized for device native deployment. Megrez2 introduces a novel cross-layer expert sharing mechanism, which significantly reduces total parameter count by reusing expert modules across adjacent transformer layers while maintaining most of the model's capacity. It also incorporates pre-gated routing, enabling memory-efficient expert loading and faster inference. As the first instantiation of the Megrez2 architecture, we introduce the Megrez2-Preview model, which is pre-trained on a 5-trillion-token corpus and further enhanced through supervised fine-tuning and reinforcement learning with verifiable rewards. With only 3B activated and 7.5B stored parameters, Megrez2-Preview demonstrates competitive or superior performance compared to larger models on a wide range of tasks, including language understanding, instruction following, mathematical reasoning, and code generation. These results highlight the effectiveness of the Megrez2 architecture to achieve a balance between accuracy, efficiency, and deployability, making it a strong candidate for real-world, resource-constrained applications.
Abstract:Multi-modal large language models (MLLMs) models have made significant progress in video understanding over the past few years. However, processing long video inputs remains a major challenge due to high memory and computational costs. This makes it difficult for current models to achieve both strong performance and high efficiency in long video understanding. To address this challenge, we propose Video-XL-2, a novel MLLM that delivers superior cost-effectiveness for long-video understanding based on task-aware KV sparsification. The proposed framework operates with two key steps: chunk-based pre-filling and bi-level key-value decoding. Chunk-based pre-filling divides the visual token sequence into chunks, applying full attention within each chunk and sparse attention across chunks. This significantly reduces computational and memory overhead. During decoding, bi-level key-value decoding selectively reloads either dense or sparse key-values for each chunk based on its relevance to the task. This approach further improves memory efficiency and enhances the model's ability to capture fine-grained information. Video-XL-2 achieves state-of-the-art performance on various long video understanding benchmarks, outperforming existing open-source lightweight models. It also demonstrates exceptional efficiency, capable of processing over 10,000 frames on a single NVIDIA A100 (80GB) GPU and thousands of frames in just a few seconds.
Abstract:Modern deep learning models are highly overparameterized, resulting in large sets of parameter configurations that yield the same outputs. A significant portion of this redundancy is explained by symmetries in the parameter space--transformations that leave the network function unchanged. These symmetries shape the loss landscape and constrain learning dynamics, offering a new lens for understanding optimization, generalization, and model complexity that complements existing theory of deep learning. This survey provides an overview of parameter space symmetry. We summarize existing literature, uncover connections between symmetry and learning theory, and identify gaps and opportunities in this emerging field.
Abstract:Neural network minima are often connected by curves along which train and test loss remain nearly constant, a phenomenon known as mode connectivity. While this property has enabled applications such as model merging and fine-tuning, its theoretical explanation remains unclear. We propose a new approach to exploring the connectedness of minima using parameter space symmetry. By linking the topology of symmetry groups to that of the minima, we derive the number of connected components of the minima of linear networks and show that skip connections reduce this number. We then examine when mode connectivity and linear mode connectivity hold or fail, using parameter symmetries which account for a significant part of the minimum. Finally, we provide explicit expressions for connecting curves in the minima induced by symmetry. Using the curvature of these curves, we derive conditions under which linear mode connectivity approximately holds. Our findings highlight the role of continuous symmetries in understanding the neural network loss landscape.