WSI-LLaVA: A Multimodal Large Language Model for Whole Slide Image

Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to bypass crucial morphological features that pathologists rely on for diagnosis. To address these challenges, we first introduce WSI-Bench, a large-scale morphology-aware benchmark containing 180k VQA pairs from 9,850 WSIs across 30 cancer types, designed to evaluate MLLMs' understanding of morphological characteristics crucial for accurate diagnosis. Building upon this benchmark, we present WSI-LLaVA, a novel framework for gigapixel WSI understanding that employs a three-stage training approach: WSI-text alignment, feature space alignment, and task-specific instruction tuning. To better assess model performance in pathological contexts, we develop two specialized WSI metrics: WSI-Precision and WSI-Relevance. Experimental results demonstrate that WSI-LLaVA outperforms existing models across all capability dimensions, with a significant improvement in morphological analysis, establishing a clear correlation between morphological understanding and diagnostic accuracy.

Fox-1 Technical Report

We present Fox-1, a series of small language models (SLMs) consisting of Fox-1-1.6B and Fox-1-1.6B-Instruct-v0.1. These models are pre-trained on 3 trillion tokens of web-scraped document data and fine-tuned with 5 billion tokens of instruction-following and multi-turn conversation data. Aiming to improve the pre-training efficiency, Fox-1-1.6B model introduces a novel 3-stage data curriculum across all the training data with 2K-8K sequence length. In architecture design, Fox-1 features a deeper layer structure, an expanded vocabulary, and utilizes Grouped Query Attention (GQA), offering a performant and efficient architecture compared to other SLMs. Fox-1 achieves better or on-par performance in various benchmarks compared to StableLM-2-1.6B, Gemma-2B, Qwen1.5-1.8B, and OpenELM1.1B, with competitive inference speed and throughput. The model weights have been released under the Apache 2.0 license, where we aim to promote the democratization of LLMs and make them fully accessible to the whole open-source community.

Alopex: A Computational Framework for Enabling On-Device Function Calls with LLMs

The rapid advancement of Large Language Models (LLMs) has led to their increased integration into mobile devices for personalized assistance, which enables LLMs to call external API functions to enhance their performance. However, challenges such as data scarcity, ineffective question formatting, and catastrophic forgetting hinder the development of on-device LLM agents. To tackle these issues, we propose Alopex, a framework that enables precise on-device function calls using the Fox LLM. Alopex introduces a logic-based method for generating high-quality training data and a novel ``description-question-output'' format for fine-tuning, reducing risks of function information leakage. Additionally, a data mixing strategy is used to mitigate catastrophic forgetting, combining function call data with textbook datasets to enhance performance in various tasks. Experimental results show that Alopex improves function call accuracy and significantly reduces catastrophic forgetting, providing a robust solution for integrating function call capabilities into LLMs without manual intervention.

Bridge-Coder: Unlocking LLMs' Potential to Overcome Language Gaps in Low-Resource Code

Large Language Models (LLMs) demonstrate strong proficiency in generating code for high-resource programming languages (HRPLs) like Python but struggle significantly with low-resource programming languages (LRPLs) such as Racket or D. This performance gap deepens the digital divide, preventing developers using LRPLs from benefiting equally from LLM advancements and reinforcing disparities in innovation within underrepresented programming communities. While generating additional training data for LRPLs is promising, it faces two key challenges: manual annotation is labor-intensive and costly, and LLM-generated LRPL code is often of subpar quality. The underlying cause of this issue is the gap between natural language to programming language gap (NL-PL Gap), which is especially pronounced in LRPLs due to limited aligned data. In this work, we introduce a novel approach called Bridge-Coder, which leverages LLMs' intrinsic capabilities to enhance the performance on LRPLs. Our method consists of two key stages. Bridge Generation, where we create high-quality dataset by utilizing LLMs' general knowledge understanding, proficiency in HRPLs, and in-context learning abilities. Then, we apply the Bridged Alignment, which progressively improves the alignment between NL instructions and LRPLs. Experimental results across multiple LRPLs show that Bridge-Coder significantly enhances model performance, demonstrating the effectiveness and generalization of our approach. Furthermore, we offer a detailed analysis of the key components of our method, providing valuable insights for future work aimed at addressing the challenges associated with LRPLs.

Personalized Visual Instruction Tuning

Recent advancements in multimodal large language models (MLLMs) have demonstrated significant progress; however, these models exhibit a notable limitation, which we refer to as "face blindness". Specifically, they can engage in general conversations but fail to conduct personalized dialogues targeting at specific individuals. This deficiency hinders the application of MLLMs in personalized settings, such as tailored visual assistants on mobile devices, or domestic robots that need to recognize members of the family. In this paper, we introduce Personalized Visual Instruction Tuning (PVIT), a novel data curation and training framework designed to enable MLLMs to identify target individuals within an image and engage in personalized and coherent dialogues. Our approach involves the development of a sophisticated pipeline that autonomously generates training data containing personalized conversations. This pipeline leverages the capabilities of various visual experts, image generation models, and (multi-modal) large language models. To evaluate the personalized potential of MLLMs, we present a benchmark called P-Bench, which encompasses various question types with different levels of difficulty. The experiments demonstrate a substantial personalized performance enhancement after fine-tuning with our curated dataset.

PolyRouter: A Multi-LLM Querying System

With the rapid growth of Large Language Models (LLMs) across various domains, numerous new LLMs have emerged, each possessing domain-specific expertise. This proliferation has highlighted the need for quick, high-quality, and cost-effective LLM query response methods. Yet, no single LLM exists to efficiently balance this trilemma. Some models are powerful but extremely costly, while others are fast and inexpensive but qualitatively inferior. To address this challenge, we present PolyRouter, a non-monolithic LLM querying system that seamlessly integrates various LLM experts into a single query interface and dynamically routes incoming queries to the most high-performant expert based on query's requirements. Through extensive experiments, we demonstrate that when compared to standalone expert models, PolyRouter improves query efficiency by up to 40%, and leads to significant cost reductions of up to 30%, while maintaining or enhancing model performance by up to 10%.

FIRST: Teach A Reliable Large Language Model Through Efficient Trustworthy Distillation

Large language models (LLMs) have become increasingly prevalent in our daily lives, leading to an expectation for LLMs to be trustworthy -- - both accurate and well-calibrated (the prediction confidence should align with its ground truth correctness likelihood). Nowadays, fine-tuning has become the most popular method for adapting a model to practical usage by significantly increasing accuracy on downstream tasks. Despite the great accuracy it achieves, we found fine-tuning is still far away from satisfactory trustworthiness due to "tuning-induced mis-calibration". In this paper, we delve deeply into why and how mis-calibration exists in fine-tuned models, and how distillation can alleviate the issue. Then we further propose a brand new method named Efficient Trustworthy Distillation (FIRST), which utilizes a small portion of teacher's knowledge to obtain a reliable language model in a cost-efficient way. Specifically, we identify the "concentrated knowledge" phenomenon during distillation, which can significantly reduce the computational burden. Then we apply a "trustworthy maximization" process to optimize the utilization of this small portion of concentrated knowledge before transferring it to the student. Experimental results demonstrate the effectiveness of our method, where better accuracy (+2.3%) and less mis-calibration (-10%) are achieved on average across both in-domain and out-of-domain scenarios, indicating better trustworthiness.

TAGCOS: Task-agnostic Gradient Clustered Coreset Selection for Instruction Tuning Data

Instruction tuning has achieved unprecedented success in NLP, turning large language models into versatile chatbots. However, the increasing variety and volume of instruction datasets demand significant computational resources. To address this, it is essential to extract a small and highly informative subset (i.e., Coreset) that achieves comparable performance to the full dataset. Achieving this goal poses non-trivial challenges: 1) data selection requires accurate data representations that reflect the training samples' quality, 2) considering the diverse nature of instruction datasets, and 3) ensuring the efficiency of the coreset selection algorithm for large models. To address these challenges, we propose Task-Agnostic Gradient Clustered COreset Selection (TAGCOS). Specifically, we leverage sample gradients as the data representations, perform clustering to group similar data, and apply an efficient greedy algorithm for coreset selection. Experimental results show that our algorithm, selecting only 5% of the data, surpasses other unsupervised methods and achieves performance close to that of the full dataset.

TheoremLlama: Transforming General-Purpose LLMs into Lean4 Experts

Proving mathematical theorems using computer-verifiable formal languages like Lean significantly impacts mathematical reasoning. One approach to formal theorem proving involves generating complete proofs using Large Language Models (LLMs) based on Natural Language (NL) proofs. Similar methods have shown promising results in code generation. However, most modern LLMs exhibit suboptimal performance due to the scarcity of aligned NL and Formal Language (FL) theorem-proving data. This scarcity results in a paucity of methodologies for training LLMs and techniques to fully utilize their capabilities in composing formal proofs. To address the challenges, this paper proposes **TheoremLlama**, an end-to-end framework to train a general-purpose LLM to become a Lean4 expert. This framework encompasses NL-FL aligned dataset generation methods, training approaches for the LLM formal theorem prover, and techniques for LLM Lean4 proof writing. Using the dataset generation method, we provide *Open Bootstrapped Theorems* (OBT), an NL-FL aligned and bootstrapped dataset. A key innovation in this framework is the NL-FL bootstrapping method, where NL proofs are integrated into Lean4 code for training datasets, leveraging the NL reasoning ability of LLMs for formal reasoning. The **TheoremLlama** framework achieves cumulative accuracies of 36.48% and 33.61% on MiniF2F-Valid and Test datasets respectively, surpassing the GPT-4 baseline of 22.95% and 25.41%. We have also open-sourced our model checkpoints and generated dataset, and will soon make all the code publicly available.

ScaleBiO: Scalable Bilevel Optimization for LLM Data Reweighting

Bilevel optimization has shown its utility across various machine learning settings, yet most algorithms in practice require second-order information, making it challenging to scale them up. Only recently, a paradigm of first-order algorithms emerged, capable of effectively addressing bilevel optimization problems. Nevertheless, the practical efficiency of this paradigm remains unverified, particularly in the context of large language models (LLMs). This paper introduces the first scalable instantiation of this paradigm called ScaleBiO, focusing on bilevel optimization for large-scale LLM data reweighting. By combining with a recently proposed memory-efficient training technique called LISA, our novel algorithm allows the paradigm to scale to 34-billion-parameter LLMs on eight A40 GPUs, marking the first successful application of bilevel optimization under practical scenarios for large-sized LLMs. Empirically, extensive experiments on data reweighting verify the effectiveness of ScaleBiO for different-scaled models, including GPT-2, LLaMA-3-8B, GPT-NeoX-20B, and Yi-34B, where bilevel optimization succeeds in filtering irrelevant data samples and selecting informative samples. Theoretically, ScaleBiO ensures the optimality of the learned data weights, along with a convergence guarantee matching the conventional first-order bilevel optimization paradigm on smooth and strongly convex objectives.