Opportunistic Promptable Segmentation: Leveraging Routine Radiological Annotations to Guide 3D CT Lesion Segmentation

The development of machine learning models for CT imaging depends on the availability of large, high-quality, and diverse annotated datasets. Although large volumes of CT images and reports are readily available in clinical picture archiving and communication systems (PACS), 3D segmentations of critical findings are costly to obtain, typically requiring extensive manual annotation by radiologists. On the other hand, it is common for radiologists to provide limited annotations of findings during routine reads, such as line measurements and arrows, that are often stored in PACS as GSPS objects. We posit that these sparse annotations can be extracted along with CT volumes and converted into 3D segmentations using promptable segmentation models, a paradigm we term Opportunistic Promptable Segmentation. To enable this paradigm, we propose SAM2CT, the first promptable segmentation model designed to convert radiologist annotations into 3D segmentations in CT volumes. SAM2CT builds upon SAM2 by extending the prompt encoder to support arrow and line inputs and by introducing Memory-Conditioned Memories (MCM), a memory encoding strategy tailored to 3D medical volumes. On public lesion segmentation benchmarks, SAM2CT outperforms existing promptable segmentation models and similarly trained baselines, achieving Dice similarity coefficients of 0.649 for arrow prompts and 0.757 for line prompts. Applying the model to pre-existing GSPS annotations from a clinical PACS (N = 60), SAM2CT generates 3D segmentations that are clinically acceptable or require only minor adjustments in 87% of cases, as scored by radiologists. Additionally, SAM2CT demonstrates strong zero-shot performance on select Emergency Department findings. These results suggest that large-scale mining of historical GSPS annotations represents a promising and scalable approach for generating 3D CT segmentation datasets.

SITA: Learning Speaker-Invariant and Tone-Aware Speech Representations for Low-Resource Tonal Languages

Tonal low-resource languages are widely spoken yet remain underserved by modern speech technology. A key challenge is learning representations that are robust to nuisance variation such as gender while remaining tone-aware for different lexical meanings. To address this, we propose SITA, a lightweight adaptation recipe that enforces Speaker-Invariance and Tone-Awareness for pretrained wav2vec-style encoders. SITA uses staged multi-objective training: (i) a cross-gender contrastive objective encourages lexical consistency across speakers, while a tone-repulsive loss prevents tone collapse by explicitly separating same-word different-tone realizations; and (ii) an auxiliary Connectionist Temporal Classification (CTC)-based ASR objective with distillation stabilizes recognition-relevant structure. We evaluate primarily on Hmong, a highly tonal and severely under-resourced language where off-the-shelf multilingual encoders fail to represent tone effectively. On a curated Hmong word corpus, SITA improves cross-gender lexical retrieval accuracy, while maintaining usable ASR accuracy relative to an ASR-adapted XLS-R teacher. We further observe similar gains when transferring the same recipe to Mandarin, suggesting SITA is a general, plug-in approach for adapting multilingual speech encoders to tonal languages.

RiskCueBench: Benchmarking Anticipatory Reasoning from Early Risk Cues in Video-Language Models

With the rapid growth of video centered social media, the ability to anticipate risky events from visual data is a promising direction for ensuring public safety and preventing real world accidents. Prior work has extensively studied supervised video risk assessment across domains such as driving, protests, and natural disasters. However, many existing datasets provide models with access to the full video sequence, including the accident itself, which substantially reduces the difficulty of the task. To better reflect real world conditions, we introduce a new video understanding benchmark RiskCueBench in which videos are carefully annotated to identify a risk signal clip, defined as the earliest moment that indicates a potential safety concern. Experimental results reveal a significant gap in current systems ability to interpret evolving situations and anticipate future risky events from early visual signals, highlighting important challenges for deploying video risk prediction models in practice.

MMGR: Multi-Modal Generative Reasoning

Video foundation models generate visually realistic and temporally coherent content, but their reliability as world simulators depends on whether they capture physical, logical, and spatial constraints. Existing metrics such as Frechet Video Distance (FVD) emphasize perceptual quality and overlook reasoning failures, including violations of causality, physics, and global consistency. We introduce MMGR (Multi-Modal Generative Reasoning Evaluation and Benchmark), a principled evaluation framework based on five reasoning abilities: Physical, Logical, 3D Spatial, 2D Spatial, and Temporal. MMGR evaluates generative reasoning across three domains: Abstract Reasoning (ARC-AGI, Sudoku), Embodied Navigation (real-world 3D navigation and localization), and Physical Commonsense (sports and compositional interactions). MMGR applies fine-grained metrics that require holistic correctness across both video and image generation. We benchmark leading video models (Veo-3, Sora-2, Wan-2.2) and image models (Nano-banana, Nano-banana Pro, GPT-4o-image, Qwen-image), revealing strong performance gaps across domains. Models show moderate success on Physical Commonsense tasks but perform poorly on Abstract Reasoning (below 10 percent accuracy on ARC-AGI) and struggle with long-horizon spatial planning in embodied settings. Our analysis highlights key limitations in current models, including overreliance on perceptual data, weak global state consistency, and objectives that reward visual plausibility over causal correctness. MMGR offers a unified diagnostic benchmark and a path toward reasoning-aware generative world models.

Class Incremental Medical Image Segmentation via Prototype-Guided Calibration and Dual-Aligned Distillation

Class incremental medical image segmentation (CIMIS) aims to preserve knowledge of previously learned classes while learning new ones without relying on old-class labels. However, existing methods 1) either adopt one-size-fits-all strategies that treat all spatial regions and feature channels equally, which may hinder the preservation of accurate old knowledge, 2) or focus solely on aligning local prototypes with global ones for old classes while overlooking their local representations in new data, leading to knowledge degradation. To mitigate the above issues, we propose Prototype-Guided Calibration Distillation (PGCD) and Dual-Aligned Prototype Distillation (DAPD) for CIMIS in this paper. Specifically, PGCD exploits prototype-to-feature similarity to calibrate class-specific distillation intensity in different spatial regions, effectively reinforcing reliable old knowledge and suppressing misleading information from old classes. Complementarily, DAPD aligns the local prototypes of old classes extracted from the current model with both global prototypes and local prototypes, further enhancing segmentation performance on old categories. Comprehensive evaluations on two widely used multi-organ segmentation benchmarks demonstrate that our method outperforms state-of-the-art methods, highlighting its robustness and generalization capabilities.

PETAR: Localized Findings Generation with Mask-Aware Vision-Language Modeling for PET Automated Reporting

Recent advances in vision-language models (VLMs) have enabled impressive multimodal reasoning, yet most medical applications remain limited to 2D imaging. In this work, we extend VLMs to 3D positron emission tomography and computed tomography (PET/CT), a domain characterized by large volumetric data, small and dispersed lesions, and lengthy radiology reports. We introduce a large-scale dataset comprising over 11,000 lesion-level descriptions paired with 3D segmentations from more than 5,000 PET/CT exams, extracted via a hybrid rule-based and large language model (LLM) pipeline. Building upon this dataset, we propose PETAR-4B, a 3D mask-aware vision-language model that integrates PET, CT, and lesion contours for spatially grounded report generation. PETAR bridges global contextual reasoning with fine-grained lesion awareness, producing clinically coherent and localized findings. Comprehensive automated and human evaluations demonstrate that PETAR substantially improves PET/CT report generation quality, advancing 3D medical vision-language understanding.

V-SEAM: Visual Semantic Editing and Attention Modulating for Causal Interpretability of Vision-Language Models

Recent advances in causal interpretability have extended from language models to vision-language models (VLMs), seeking to reveal their internal mechanisms through input interventions. While textual interventions often target semantics, visual interventions typically rely on coarse pixel-level perturbations, limiting semantic insights on multimodal integration. In this study, we introduce V-SEAM, a novel framework that combines Visual Semantic Editing and Attention Modulating for causal interpretation of VLMs. V-SEAM enables concept-level visual manipulations and identifies attention heads with positive or negative contributions to predictions across three semantic levels: objects, attributes, and relationships. We observe that positive heads are often shared within the same semantic level but vary across levels, while negative heads tend to generalize broadly. Finally, we introduce an automatic method to modulate key head embeddings, demonstrating enhanced performance for both LLaVA and InstructBLIP across three diverse VQA benchmarks. Our data and code are released at: https://github.com/petergit1/V-SEAM.

LLM Hallucination Detection: A Fast Fourier Transform Method Based on Hidden Layer Temporal Signals

Hallucination remains a critical barrier for deploying large language models (LLMs) in reliability-sensitive applications. Existing detection methods largely fall into two categories: factuality checking, which is fundamentally constrained by external knowledge coverage, and static hidden-state analysis, that fails to capture deviations in reasoning dynamics. As a result, their effectiveness and robustness remain limited. We propose HSAD (Hidden Signal Analysis-based Detection), a novel hallucination detection framework that models the temporal dynamics of hidden representations during autoregressive generation. HSAD constructs hidden-layer signals by sampling activations across layers, applies Fast Fourier Transform (FFT) to obtain frequency-domain representations, and extracts the strongest non-DC frequency component as spectral features. Furthermore, by leveraging the autoregressive nature of LLMs, HSAD identifies optimal observation points for effective and reliable detection. Across multiple benchmarks, including TruthfulQA, HSAD achieves over 10 percentage points improvement compared to prior state-of-the-art methods. By integrating reasoning-process modeling with frequency-domain analysis, HSAD establishes a new paradigm for robust hallucination detection in LLMs.

Exploiting Unlabeled Structures through Task Consistency Training for Versatile Medical Image Segmentation

Versatile medical image segmentation (VMIS) targets the segmentation of multiple classes, while obtaining full annotations for all classes is often impractical due to the time and labor required. Leveraging partially labeled datasets (PLDs) presents a promising alternative; however, current VMIS approaches face significant class imbalance due to the unequal category distribution in PLDs. Existing methods attempt to address this by generating pseudo-full labels. Nevertheless, these typically require additional models and often result in potential performance degradation from label noise. In this work, we introduce a Task Consistency Training (TCT) framework to address class imbalance without requiring extra models. TCT includes a backbone network with a main segmentation head (MSH) for multi-channel predictions and multiple auxiliary task heads (ATHs) for task-specific predictions. By enforcing a consistency constraint between the MSH and ATH predictions, TCT effectively utilizes unlabeled anatomical structures. To avoid error propagation from low-consistency, potentially noisy data, we propose a filtering strategy to exclude such data. Additionally, we introduce a unified auxiliary uncertainty-weighted loss (UAUWL) to mitigate segmentation quality declines caused by the dominance of specific tasks. Extensive experiments on eight abdominal datasets from diverse clinical sites demonstrate our approach's effectiveness.

Scaling Up Audio-Synchronized Visual Animation: An Efficient Training Paradigm

Recent advances in audio-synchronized visual animation enable control of video content using audios from specific classes. However, existing methods rely heavily on expensive manual curation of high-quality, class-specific training videos, posing challenges to scaling up to diverse audio-video classes in the open world. In this work, we propose an efficient two-stage training paradigm to scale up audio-synchronized visual animation using abundant but noisy videos. In stage one, we automatically curate large-scale videos for pretraining, allowing the model to learn diverse but imperfect audio-video alignments. In stage two, we finetune the model on manually curated high-quality examples, but only at a small scale, significantly reducing the required human effort. We further enhance synchronization by allowing each frame to access rich audio context via multi-feature conditioning and window attention. To efficiently train the model, we leverage pretrained text-to-video generator and audio encoders, introducing only 1.9\% additional trainable parameters to learn audio-conditioning capability without compromising the generator's prior knowledge. For evaluation, we introduce AVSync48, a benchmark with videos from 48 classes, which is 3$\times$ more diverse than previous benchmarks. Extensive experiments show that our method significantly reduces reliance on manual curation by over 10$\times$, while generalizing to many open classes.