MAST-Pro: Dynamic Mixture-of-Experts for Adaptive Segmentation of Pan-Tumors with Knowledge-Driven Prompts

Accurate tumor segmentation is crucial for cancer diagnosis and treatment. While foundation models have advanced general-purpose segmentation, existing methods still struggle with: (1) limited incorporation of medical priors, (2) imbalance between generic and tumor-specific features, and (3) high computational costs for clinical adaptation. To address these challenges, we propose MAST-Pro (Mixture-of-experts for Adaptive Segmentation of pan-Tumors with knowledge-driven Prompts), a novel framework that integrates dynamic Mixture-of-Experts (D-MoE) and knowledge-driven prompts for pan-tumor segmentation. Specifically, text and anatomical prompts provide domain-specific priors, guiding tumor representation learning, while D-MoE dynamically selects experts to balance generic and tumor-specific feature learning, improving segmentation accuracy across diverse tumor types. To enhance efficiency, we employ Parameter-Efficient Fine-Tuning (PEFT), optimizing MAST-Pro with significantly reduced computational overhead. Experiments on multi-anatomical tumor datasets demonstrate that MAST-Pro outperforms state-of-the-art approaches, achieving up to a 5.20% improvement in average DSC while reducing trainable parameters by 91.04%, without compromising accuracy.

LazyMAR: Accelerating Masked Autoregressive Models via Feature Caching

Masked Autoregressive (MAR) models have emerged as a promising approach in image generation, expected to surpass traditional autoregressive models in computational efficiency by leveraging the capability of parallel decoding. However, their dependence on bidirectional self-attention inherently conflicts with conventional KV caching mechanisms, creating unexpected computational bottlenecks that undermine their expected efficiency. To address this problem, this paper studies the caching mechanism for MAR by leveraging two types of redundancy: Token Redundancy indicates that a large portion of tokens have very similar representations in the adjacent decoding steps, which allows us to first cache them in previous steps and then reuse them in the later steps. Condition Redundancy indicates that the difference between conditional and unconditional output in classifier-free guidance exhibits very similar values in adjacent steps. Based on these two redundancies, we propose LazyMAR, which introduces two caching mechanisms to handle them one by one. LazyMAR is training-free and plug-and-play for all MAR models. Experimental results demonstrate that our method achieves 2.83 times acceleration with almost no drop in generation quality. Our codes will be released in https://github.com/feihongyan1/LazyMAR.

RoMA: Scaling up Mamba-based Foundation Models for Remote Sensing

Recent advances in self-supervised learning for Vision Transformers (ViTs) have fueled breakthroughs in remote sensing (RS) foundation models. However, the quadratic complexity of self-attention poses a significant barrier to scalability, particularly for large models and high-resolution images. While the linear-complexity Mamba architecture offers a promising alternative, existing RS applications of Mamba remain limited to supervised tasks on small, domain-specific datasets. To address these challenges, we propose RoMA, a framework that enables scalable self-supervised pretraining of Mamba-based RS foundation models using large-scale, diverse, unlabeled data. RoMA enhances scalability for high-resolution images through a tailored auto-regressive learning strategy, incorporating two key innovations: 1) a rotation-aware pretraining mechanism combining adaptive cropping with angular embeddings to handle sparsely distributed objects with arbitrary orientations, and 2) multi-scale token prediction objectives that address the extreme variations in object scales inherent to RS imagery. Systematic empirical studies validate that Mamba adheres to RS data and parameter scaling laws, with performance scaling reliably as model and data size increase. Furthermore, experiments across scene classification, object detection, and semantic segmentation tasks demonstrate that RoMA-pretrained Mamba models consistently outperform ViT-based counterparts in both accuracy and computational efficiency. The source code and pretrained models will be released at https://github.com/MiliLab/RoMA.

Uni-AdaFocus: Spatial-temporal Dynamic Computation for Video Recognition

This paper presents a comprehensive exploration of the phenomenon of data redundancy in video understanding, with the aim to improve computational efficiency. Our investigation commences with an examination of spatial redundancy, which refers to the observation that the most informative region in each video frame usually corresponds to a small image patch, whose shape, size and location shift smoothly across frames. Motivated by this phenomenon, we formulate the patch localization problem as a dynamic decision task, and introduce a spatially adaptive video recognition approach, termed AdaFocus. In specific, a lightweight encoder is first employed to quickly process the full video sequence, whose features are then utilized by a policy network to identify the most task-relevant regions. Subsequently, the selected patches are inferred by a high-capacity deep network for the final prediction. The full model can be trained in end-to-end conveniently. Furthermore, AdaFocus can be extended by further considering temporal and sample-wise redundancies, i.e., allocating the majority of computation to the most task-relevant frames, and minimizing the computation spent on relatively "easier" videos. Our resulting approach, Uni-AdaFocus, establishes a comprehensive framework that seamlessly integrates spatial, temporal, and sample-wise dynamic computation, while it preserves the merits of AdaFocus in terms of efficient end-to-end training and hardware friendliness. In addition, Uni-AdaFocus is general and flexible as it is compatible with off-the-shelf efficient backbones (e.g., TSM and X3D), which can be readily deployed as our feature extractor, yielding a significantly improved computational efficiency. Empirically, extensive experiments based on seven benchmark datasets and three application scenarios substantiate that Uni-AdaFocus is considerably more efficient than the competitive baselines.

ENAT: Rethinking Spatial-temporal Interactions in Token-based Image Synthesis

Recently, token-based generation have demonstrated their effectiveness in image synthesis. As a representative example, non-autoregressive Transformers (NATs) can generate decent-quality images in a few steps. NATs perform generation in a progressive manner, where the latent tokens of a resulting image are incrementally revealed. At each step, the unrevealed image regions are padded with mask tokens and inferred by NAT. In this paper, we delve into the mechanisms behind the effectiveness of NATs and uncover two important patterns that naturally emerge from NATs: Spatially (within a step), although mask and visible tokens are processed uniformly by NATs, the interactions between them are highly asymmetric. In specific, mask tokens mainly gather information for decoding, while visible tokens tend to primarily provide information, and their deep representations can be built only upon themselves. Temporally (across steps), the interactions between adjacent generation steps mostly concentrate on updating the representations of a few critical tokens, while the computation for the majority of tokens is generally repetitive. Driven by these findings, we propose EfficientNAT (ENAT), a NAT model that explicitly encourages these critical interactions inherent in NATs. At the spatial level, we disentangle the computations of visible and mask tokens by encoding visible tokens independently, while decoding mask tokens conditioned on the fully encoded visible tokens. At the temporal level, we prioritize the computation of the critical tokens at each step, while maximally reusing previously computed token representations to supplement necessary information. ENAT improves the performance of NATs notably with significantly reduced computational cost. Experiments on ImageNet-256, ImageNet-512 and MS-COCO validate the effectiveness of ENAT. Code is available at https://github.com/LeapLabTHU/ENAT.

DeeR-VLA: Dynamic Inference of Multimodal Large Language Models for Efficient Robot Execution

MLLMs have demonstrated remarkable comprehension and reasoning capabilities with complex language and visual data. These advances have spurred the vision of establishing a generalist robotic MLLM proficient in understanding complex human instructions and accomplishing various embodied tasks. However, developing MLLMs for real-world robots is challenging due to the typically limited computation and memory capacities available on robotic platforms. In contrast, the inference of MLLMs involves storing billions of parameters and performing tremendous computation, imposing significant hardware demands. In our paper, we propose a Dynamic Early-Exit Framework for Robotic Vision-Language-Action Model (DeeR-VLA, or simply DeeR) that automatically adjusts the size of the activated MLLM based on each situation at hand. The approach leverages a multi-exit architecture in MLLMs, which allows the model to terminate processing once a proper size of the model has been activated for a specific situation, thus avoiding further redundant computation. Additionally, we develop novel algorithms that establish early-termination criteria for DeeR, conditioned on predefined demands such as average computational cost (i.e., power consumption), as well as peak computational consumption (i.e., latency) and GPU memory usage. These enhancements ensure that DeeR operates efficiently under varying resource constraints while maintaining competitive performance. On the CALVIN robot manipulation benchmark, DeeR demonstrates significant reductions in computational costs of LLM by 5.2-6.5x and GPU memory of LLM by 2-6x without compromising performance. Code and checkpoints are available at https://github.com/yueyang130/DeeR-VLA.

Towards General Text-guided Image Synthesis for Customized Multimodal Brain MRI Generation

Multimodal brain magnetic resonance (MR) imaging is indispensable in neuroscience and neurology. However, due to the accessibility of MRI scanners and their lengthy acquisition time, multimodal MR images are not commonly available. Current MR image synthesis approaches are typically trained on independent datasets for specific tasks, leading to suboptimal performance when applied to novel datasets and tasks. Here, we present TUMSyn, a Text-guided Universal MR image Synthesis generalist model, which can flexibly generate brain MR images with demanded imaging metadata from routinely acquired scans guided by text prompts. To ensure TUMSyn's image synthesis precision, versatility, and generalizability, we first construct a brain MR database comprising 31,407 3D images with 7 MRI modalities from 13 centers. We then pre-train an MRI-specific text encoder using contrastive learning to effectively control MR image synthesis based on text prompts. Extensive experiments on diverse datasets and physician assessments indicate that TUMSyn can generate clinically meaningful MR images with specified imaging metadata in supervised and zero-shot scenarios. Therefore, TUMSyn can be utilized along with acquired MR scan(s) to facilitate large-scale MRI-based screening and diagnosis of brain diseases.

Basket-Enhanced Heterogenous Hypergraph for Price-Sensitive Next Basket Recommendation

Next Basket Recommendation (NBR) is a new type of recommender system that predicts combinations of items users are likely to purchase together. Existing NBR models often overlook a crucial factor, which is price, and do not fully capture item-basket-user interactions. To address these limitations, we propose a novel method called Basket-augmented Dynamic Heterogeneous Hypergraph (BDHH). BDHH utilizes a heterogeneous multi-relational graph to capture the intricate relationships among item features, with price as a critical factor. Moreover, our approach includes a basket-guided dynamic augmentation network that could dynamically enhances item-basket-user interactions. Experiments on real-world datasets demonstrate that BDHH significantly improves recommendation accuracy, providing a more comprehensive understanding of user behavior.

AdaNAT: Exploring Adaptive Policy for Token-Based Image Generation

Recent studies have demonstrated the effectiveness of token-based methods for visual content generation. As a representative work, non-autoregressive Transformers (NATs) are able to synthesize images with decent quality in a small number of steps. However, NATs usually necessitate configuring a complicated generation policy comprising multiple manually-designed scheduling rules. These heuristic-driven rules are prone to sub-optimality and come with the requirements of expert knowledge and labor-intensive efforts. Moreover, their one-size-fits-all nature cannot flexibly adapt to the diverse characteristics of each individual sample. To address these issues, we propose AdaNAT, a learnable approach that automatically configures a suitable policy tailored for every sample to be generated. In specific, we formulate the determination of generation policies as a Markov decision process. Under this framework, a lightweight policy network for generation can be learned via reinforcement learning. Importantly, we demonstrate that simple reward designs such as FID or pre-trained reward models, may not reliably guarantee the desired quality or diversity of generated samples. Therefore, we propose an adversarial reward design to guide the training of policy networks effectively. Comprehensive experiments on four benchmark datasets, i.e., ImageNet-256 & 512, MS-COCO, and CC3M, validate the effectiveness of AdaNAT. Code and pre-trained models will be released at https://github.com/LeapLabTHU/AdaNAT.

UniTTA: Unified Benchmark and Versatile Framework Towards Realistic Test-Time Adaptation

Test-Time Adaptation (TTA) aims to adapt pre-trained models to the target domain during testing. In reality, this adaptability can be influenced by multiple factors. Researchers have identified various challenging scenarios and developed diverse methods to address these challenges, such as dealing with continual domain shifts, mixed domains, and temporally correlated or imbalanced class distributions. Despite these efforts, a unified and comprehensive benchmark has yet to be established. To this end, we propose a Unified Test-Time Adaptation (UniTTA) benchmark, which is comprehensive and widely applicable. Each scenario within the benchmark is fully described by a Markov state transition matrix for sampling from the original dataset. The UniTTA benchmark considers both domain and class as two independent dimensions of data and addresses various combinations of imbalance/balance and i.i.d./non-i.i.d./continual conditions, covering a total of \( (2 \times 3)^2 = 36 \) scenarios. It establishes a comprehensive evaluation benchmark for realistic TTA and provides a guideline for practitioners to select the most suitable TTA method. Alongside this benchmark, we propose a versatile UniTTA framework, which includes a Balanced Domain Normalization (BDN) layer and a COrrelated Feature Adaptation (COFA) method--designed to mitigate distribution gaps in domain and class, respectively. Extensive experiments demonstrate that our UniTTA framework excels within the UniTTA benchmark and achieves state-of-the-art performance on average. Our code is available at \url{https://github.com/LeapLabTHU/UniTTA}.