UNSCT-HRNet: Modeling Anatomical Uncertainty for Landmark Detection in Total Hip Arthroplasty

Total hip arthroplasty (THA) relies on accurate landmark detection from radiographic images, but unstructured data caused by irregular patient postures or occluded anatomical markers pose significant challenges for existing methods. To address this, we propose UNSCT-HRNet (Unstructured CT - High-Resolution Net), a deep learning-based framework that integrates a Spatial Relationship Fusion (SRF) module and an Uncertainty Estimation (UE) module. The SRF module, utilizing coordinate convolution and polarized attention, enhances the model's ability to capture complex spatial relationships. Meanwhile, the UE module which based on entropy ensures predictions are anatomically relevant. For unstructured data, the proposed method can predict landmarks without relying on the fixed number of points, which shows higher accuracy and better robustness comparing with the existing methods. Our UNSCT-HRNet demonstrates over a 60% improvement across multiple metrics in unstructured data. The experimental results also reveal that our approach maintains good performance on the structured dataset. Overall, the proposed UNSCT-HRNet has the potential to be used as a new reliable, automated solution for THA surgical planning and postoperative monitoring.

Quantifying and Mitigating Privacy Risks for Tabular Generative Models

Synthetic data from generative models emerges as the privacy-preserving data-sharing solution. Such a synthetic data set shall resemble the original data without revealing identifiable private information. The backbone technology of tabular synthesizers is rooted in image generative models, ranging from Generative Adversarial Networks (GANs) to recent diffusion models. Recent prior work sheds light on the utility-privacy tradeoff on tabular data, revealing and quantifying privacy risks on synthetic data. We first conduct an exhaustive empirical analysis, highlighting the utility-privacy tradeoff of five state-of-the-art tabular synthesizers, against eight privacy attacks, with a special focus on membership inference attacks. Motivated by the observation of high data quality but also high privacy risk in tabular diffusion, we propose DP-TLDM, Differentially Private Tabular Latent Diffusion Model, which is composed of an autoencoder network to encode the tabular data and a latent diffusion model to synthesize the latent tables. Following the emerging f-DP framework, we apply DP-SGD to train the auto-encoder in combination with batch clipping and use the separation value as the privacy metric to better capture the privacy gain from DP algorithms. Our empirical evaluation demonstrates that DP-TLDM is capable of achieving a meaningful theoretical privacy guarantee while also significantly enhancing the utility of synthetic data. Specifically, compared to other DP-protected tabular generative models, DP-TLDM improves the synthetic quality by an average of 35% in data resemblance, 15% in the utility for downstream tasks, and 50% in data discriminability, all while preserving a comparable level of privacy risk.