GDiffRetro: Retrosynthesis Prediction with Dual Graph Enhanced Molecular Representation and Diffusion Generation

Retrosynthesis prediction focuses on identifying reactants capable of synthesizing a target product. Typically, the retrosynthesis prediction involves two phases: Reaction Center Identification and Reactant Generation. However, we argue that most existing methods suffer from two limitations in the two phases: (i) Existing models do not adequately capture the ``face'' information in molecular graphs for the reaction center identification. (ii) Current approaches for the reactant generation predominantly use sequence generation in a 2D space, which lacks versatility in generating reasonable distributions for completed reactive groups and overlooks molecules' inherent 3D properties. To overcome the above limitations, we propose GDiffRetro. For the reaction center identification, GDiffRetro uniquely integrates the original graph with its corresponding dual graph to represent molecular structures, which helps guide the model to focus more on the faces in the graph. For the reactant generation, GDiffRetro employs a conditional diffusion model in 3D to further transform the obtained synthon into a complete reactant. Our experimental findings reveal that GDiffRetro outperforms state-of-the-art semi-template models across various evaluative metrics.

Humanoid Locomotion and Manipulation: Current Progress and Challenges in Control, Planning, and Learning

Humanoid robots have great potential to perform various human-level skills. These skills involve locomotion, manipulation, and cognitive capabilities. Driven by advances in machine learning and the strength of existing model-based approaches, these capabilities have progressed rapidly, but often separately. Therefore, a timely overview of current progress and future trends in this fast-evolving field is essential. This survey first summarizes the model-based planning and control that have been the backbone of humanoid robotics for the past three decades. We then explore emerging learning-based methods, with a focus on reinforcement learning and imitation learning that enhance the versatility of loco-manipulation skills. We examine the potential of integrating foundation models with humanoid embodiments, assessing the prospects for developing generalist humanoid agents. In addition, this survey covers emerging research for whole-body tactile sensing that unlocks new humanoid skills that involve physical interactions. The survey concludes with a discussion of the challenges and future trends.

Versatile Locomotion Skills for Hexapod Robots

Hexapod robots are potentially suitable for carrying out tasks in cluttered environments since they are stable, compact, and light weight. They also have multi-joint legs and variable height bodies that make them good candidates for tasks such as stairs climbing and squeezing under objects in a typical home environment or an attic. Expanding on our previous work on joist climbing in attics, we train a legged hexapod equipped with a depth camera and visual inertial odometry (VIO) to perform three tasks: climbing stairs, avoiding obstacles, and squeezing under obstacles such as a table. Our policies are trained with simulation data only and can be deployed on lowcost hardware not requiring real-time joint state feedback. We train our model in a teacher-student model with 2 phases: In phase 1, we use reinforcement learning with access to privileged information such as height maps and joint feedback. In phase 2, we use supervised learning to distill the model into one with access to only onboard observations, consisting of egocentric depth images and robot pose captured by a tracking VIO camera. By manipulating available privileged information, constructing simulation terrains, and refining reward functions during phase 1 training, we are able to train the robots with skills that are robust in non-ideal physical environments. We demonstrate successful sim-to-real transfer and achieve high success rates across all three tasks in physical experiments.

Learning Multi-Agent Loco-Manipulation for Long-Horizon Quadrupedal Pushing

Recently, quadrupedal locomotion has achieved significant success, but their manipulation capabilities, particularly in handling large objects, remain limited, restricting their usefulness in demanding real-world applications such as search and rescue, construction, industrial automation, and room organization. This paper tackles the task of obstacle-aware, long-horizon pushing by multiple quadrupedal robots. We propose a hierarchical multi-agent reinforcement learning framework with three levels of control. The high-level controller integrates an RRT planner and a centralized adaptive policy to generate subgoals, while the mid-level controller uses a decentralized goal-conditioned policy to guide the robots toward these sub-goals. A pre-trained low-level locomotion policy executes the movement commands. We evaluate our method against several baselines in simulation, demonstrating significant improvements over baseline approaches, with 36.0% higher success rates and 24.5% reduction in completion time than the best baseline. Our framework successfully enables long-horizon, obstacle-aware manipulation tasks like Push-Cuboid and Push-T on Go1 robots in the real world.

Vision Language Models are In-Context Value Learners

Predicting temporal progress from visual trajectories is important for intelligent robots that can learn, adapt, and improve. However, learning such progress estimator, or temporal value function, across different tasks and domains requires both a large amount of diverse data and methods which can scale and generalize. To address these challenges, we present Generative Value Learning (\GVL), a universal value function estimator that leverages the world knowledge embedded in vision-language models (VLMs) to predict task progress. Naively asking a VLM to predict values for a video sequence performs poorly due to the strong temporal correlation between successive frames. Instead, GVL poses value estimation as a temporal ordering problem over shuffled video frames; this seemingly more challenging task encourages VLMs to more fully exploit their underlying semantic and temporal grounding capabilities to differentiate frames based on their perceived task progress, consequently producing significantly better value predictions. Without any robot or task specific training, GVL can in-context zero-shot and few-shot predict effective values for more than 300 distinct real-world tasks across diverse robot platforms, including challenging bimanual manipulation tasks. Furthermore, we demonstrate that GVL permits flexible multi-modal in-context learning via examples from heterogeneous tasks and embodiments, such as human videos. The generality of GVL enables various downstream applications pertinent to visuomotor policy learning, including dataset filtering, success detection, and advantage-weighted regression -- all without any model training or finetuning.

OpenWebVoyager: Building Multimodal Web Agents via Iterative Real-World Exploration, Feedback and Optimization

The rapid development of large language and multimodal models has sparked significant interest in using proprietary models, such as GPT-4o, to develop autonomous agents capable of handling real-world scenarios like web navigation. Although recent open-source efforts have tried to equip agents with the ability to explore environments and continuously improve over time, they are building text-only agents in synthetic environments where the reward signals are clearly defined. Such agents struggle to generalize to realistic settings that require multimodal perception abilities and lack ground-truth signals. In this paper, we introduce an open-source framework designed to facilitate the development of multimodal web agent that can autonomously conduct real-world exploration and improve itself. We first train the base model with imitation learning to gain the basic abilities. We then let the agent explore the open web and collect feedback on its trajectories. After that, it further improves its policy by learning from well-performing trajectories judged by another general-purpose model. This exploration-feedback-optimization cycle can continue for several iterations. Experimental results show that our web agent successfully improves itself after each iteration, demonstrating strong performance across multiple test sets.

LongMemEval: Benchmarking Chat Assistants on Long-Term Interactive Memory

Recent large language model (LLM)-driven chat assistant systems have integrated memory components to track user-assistant chat histories, enabling more accurate and personalized responses. However, their long-term memory capabilities in sustained interactions remain underexplored. This paper introduces LongMemEval, a comprehensive benchmark designed to evaluate five core long-term memory abilities of chat assistants: information extraction, multi-session reasoning, temporal reasoning, knowledge updates, and abstention. With 500 meticulously curated questions embedded within freely scalable user-assistant chat histories, LongMemEval presents a significant challenge to existing long-term memory systems, with commercial chat assistants and long-context LLMs showing 30% accuracy drop on memorizing information across sustained interactions. We then present a unified framework that breaks down the long-term memory design into four design choices across the indexing, retrieval, and reading stages. Built upon key experimental insights, we propose several memory designs including session decomposition for optimizing value granularity, fact-augmented key expansion for enhancing the index structure, and time-aware query expansion for refining the search scope. Experiment results show that these optimizations greatly improve both memory recall and downstream question answering on LongMemEval. Overall, our study provides valuable resources and guidance for advancing the long-term memory capabilities of LLM-based chat assistants, paving the way toward more personalized and reliable conversational AI.

LEOPARD : A Vision Language Model For Text-Rich Multi-Image Tasks

Text-rich images, where text serves as the central visual element guiding the overall understanding, are prevalent in real-world applications, such as presentation slides, scanned documents, and webpage snapshots. Tasks involving multiple text-rich images are especially challenging, as they require not only understanding the content of individual images but reasoning about inter-relationships and logical flows across multiple visual inputs. Despite the importance of these scenarios, current multimodal large language models (MLLMs) struggle to handle such tasks due to two key challenges: (1) the scarcity of high-quality instruction tuning datasets for text-rich multi-image scenarios, and (2) the difficulty in balancing image resolution with visual feature sequence length. To address these challenges, we propose \OurMethod, a MLLM designed specifically for handling vision-language tasks involving multiple text-rich images. First, we curated about one million high-quality multimodal instruction-tuning data, tailored to text-rich, multi-image scenarios. Second, we developed an adaptive high-resolution multi-image encoding module to dynamically optimize the allocation of visual sequence length based on the original aspect ratios and resolutions of the input images. Experiments across a wide range of benchmarks demonstrate our model's superior capabilities in text-rich, multi-image evaluations and competitive performance in general domain evaluations.

MHRC: Closed-loop Decentralized Multi-Heterogeneous Robot Collaboration with Large Language Models

The integration of large language models (LLMs) with robotics has significantly advanced robots' abilities in perception, cognition, and task planning. The use of natural language interfaces offers a unified approach for expressing the capability differences of heterogeneous robots, facilitating communication between them, and enabling seamless task allocation and collaboration. Currently, the utilization of LLMs to achieve decentralized multi-heterogeneous robot collaborative tasks remains an under-explored area of research. In this paper, we introduce a novel framework that utilizes LLMs to achieve decentralized collaboration among multiple heterogeneous robots. Our framework supports three robot categories, mobile robots, manipulation robots, and mobile manipulation robots, working together to complete tasks such as exploration, transportation, and organization. We developed a rich set of textual feedback mechanisms and chain-of-thought (CoT) prompts to enhance task planning efficiency and overall system performance. The mobile manipulation robot can adjust its base position flexibly, ensuring optimal conditions for grasping tasks. The manipulation robot can comprehend task requirements, seek assistance when necessary, and handle objects appropriately. Meanwhile, the mobile robot can explore the environment extensively, map object locations, and communicate this information to the mobile manipulation robot, thus improving task execution efficiency. We evaluated the framework using PyBullet, creating scenarios with three different room layouts and three distinct operational tasks. We tested various LLM models and conducted ablation studies to assess the contributions of different modules. The experimental results confirm the effectiveness and necessity of our proposed framework.

Agile Continuous Jumping in Discontinuous Terrains

We focus on agile, continuous, and terrain-adaptive jumping of quadrupedal robots in discontinuous terrains such as stairs and stepping stones. Unlike single-step jumping, continuous jumping requires accurately executing highly dynamic motions over long horizons, which is challenging for existing approaches. To accomplish this task, we design a hierarchical learning and control framework, which consists of a learned heightmap predictor for robust terrain perception, a reinforcement-learning-based centroidal-level motion policy for versatile and terrain-adaptive planning, and a low-level model-based leg controller for accurate motion tracking. In addition, we minimize the sim-to-real gap by accurately modeling the hardware characteristics. Our framework enables a Unitree Go1 robot to perform agile and continuous jumps on human-sized stairs and sparse stepping stones, for the first time to the best of our knowledge. In particular, the robot can cross two stair steps in each jump and completes a 3.5m long, 2.8m high, 14-step staircase in 4.5 seconds. Moreover, the same policy outperforms baselines in various other parkour tasks, such as jumping over single horizontal or vertical discontinuities. Experiment videos can be found at \url{https://yxyang.github.io/jumping\_cod/}.