Pocket-Dentist: On-Device Dental Image Understanding via Efficient Multimodal Large Language Models

Evaluations of dental vision-language models remain fragmented across datasets, task definitions and metrics, and often ignore their computational cost. This limits their widespread deployment for dental screening outside specialist centres, where timely inference, limited hardware, and local handling of patient images are vital for practical, privacy-preserving clinical prescreening. Here we present Pocket-Dentist, an efficiency-aware benchmark for dental multimodal question answering that brings together three datasets spanning approximately 1,159 patients, five task types and seven metrics. Across typical 14 VLMs, our results reveals an interesting observation: compact VLMs (e.g., 2B-parameter models) outperform larger VLMs in accuracy while requiring substantially lower computational costs in dental image understanding. Deployed locally on an iPhone 17 Pro, our finetuned compact VLM Pocket-Dentist-2B processed each sample in 4.31 s, reducing latency by 4.9-fold and memory use by 2.3-fold compared with a 7B baseline.

Reasoning Matters: Mitigate Hallucination in Multimodal Large Reasoning Models via Reasoning-Conditioned Preference Optimization

Multimodal Large Reasoning Models introduce the reasoning paradigm, demonstrating strong capabilities on complex vision-language tasks. However, they still suffer from severe hallucinations. Existing training-based methods typically mitigate hallucinations through response-level direct preference optimization (DPO), where the Chain-of-Thought (CoT) and the final answer are treated as a monolithic output and optimized jointly. We reveal that this formulation performs similarly to answer-only optimization, suggesting that it primarily learns answer-level preference, while leaving CoT-level supervision insufficiently exploited. To address this issue, we explicitly formulate a CoT-oriented preference term and derive Reasoning-Conditioned Direct Preference Optimization (RC-DPO), which models the CoT as a condition for answer generation and contrasts the preference for the same preferred answer under different CoT conditions, promoting answer-supportive reasoning chain alignment. To further improve optimization, we introduce a reasoning-enhanced preference data generation strategy that employs Monte Carlo Tree Search to discover visually grounded and logically consistent CoTs as positive samples, and attention-guided CoT token pruning to construct negative ones. Extensive experiments across various models and benchmarks show that RC-DPO effectively mitigates hallucinations and improves the reliability of the multimodal reasoning process.

CVSearch: Empowering Multimodal LLMs with Cognitive Visual Search for High-Resolution Image Perception

High-resolution (HR) image perception presents a key bottleneck for multimodal large language models (MLLMs). While visual search offers a promising solution, existing methods struggle with the trade-off between coverage and efficiency. Visual expert-assisted search is efficient but prone to blind spots when proposals fail, whereas scan-based search guarantees coverage at the cost of computational redundancy and semantic fragmentation. To address this dilemma, we introduce CVSearch, a training-free adaptive framework that dynamically schedules search strategies via an Assess-then-Search workflow. Specifically, CVSearch first invokes expert-assisted search when global information is insufficient, and only triggers a novel semantic-aware scanning mechanism upon failure. Distinct from rigid grid partitioning, this efficient scanning paradigm incorporates Semantic Guided Adaptive Patching to decompose images into semantically consistent regions, effectively mitigating object fragmentation. Furthermore, we devise a Dynamic Bottom-Up Search strategy driven by a Visual Complexity prior to enable efficient and precise iterative exploration of local details. Extensive experiments on HR benchmarks demonstrate that CVSearch achieves state-of-the-art accuracy while substantially improving search efficiency. Code is released at https://github.com/liliupeng28/ICML26-CVSearch.

Molecular Lead Optimization via Agentic Tool Planning

Drug discovery is a lengthy and resource-intensive process composed of multiple stages. Among these stages, lead optimization plays a critical role in transforming early hit compounds into viable drug candidates. This stage requires improving ADMET-related properties through subtle structural refinement while preserving key molecular substructures responsible for binding affinity to disease targets. Recent advances in artificial intelligence have shown promise in accelerating various aspects of drug discovery; however, most existing approaches to lead optimization rely on one-step molecular optimization, which fail to account for the long-term consequences of sequential design decisions. To address this limitation, we propose TRACE, a trajectory-aware, LLM-reasoning agent for molecular lead optimization that formulates tool selection as a sequential decision-making problem over action trajectories. Given a lead molecule and an optimization objective, TRACE makes trajectory-aware decisions over molecular optimization tools, enabling forward-looking refinement under structural constraints. Experiments on multiple ADMET optimization tasks show that our agent achieves higher optimization success, larger property improvements, and higher validity, while preserving molecular similarity compared to baseline models.

FlowErase-RL: Rethinking Concept Erasure as Reward Optimization in Flow Matching Models

Recent advances in flow matching models have significantly improved text-to-image generation quality, but also introduce growing safety risks due to the generation of harmful or undesirable content. Existing concept erasure methods are either inference-time interventions with limited effectiveness or rely on supervised fine-tuning (SFT), which requires precisely aligned data and struggles with scalability and multi-concept settings. In this paper, we propose \emph{FlowErase-RL}, the first GRPO-based framework for concept erasure in flow matching models. We reformulate concept erasure as a reward optimization problem and introduce a \textbf{dynamic dual-path reward mechanism} that jointly optimizes (i) a Concept Erasure (CE) reward to suppress target concepts and (ii) a Non-target Space (NS) reward to preserve generative fidelity. The two reward paths are adaptively balanced during training via a performance-driven switching strategy, enabling stable optimization without explicit supervision. Extensive experiments on nudity, object, and artistic style erasure demonstrate that our method achieves state-of-the-art erasure performance while maintaining strong image quality and semantic alignment. Moreover, it exhibits robust resistance to adversarial attacks and scales effectively to multi-concept scenarios. Our results establish a new paradigm for safe and controllable generation in flow matching models.

Prompt2Fingerprint: Plug-and-Play LLM Fingerprinting via Text-to-Weight Generation

The widespread deployment and redistribution of large language models (LLMs) have made model provenance tracking a critical challenge. While existing LLM fingerprinting methods, particularly active approaches that embed identity signals via fine-tuning, achieve high accuracy and robustness, they suffer from significant scalability bottlenecks. These methods typically treat fingerprint injection as an independent, one-off optimization task rather than a reusable capability, necessitating separate, resource-intensive training for every new identity. This incurs prohibitive computational costs and deployment delays. To address this, we propose Prompt2Fingerprint (P2F), the first framework that reformulates fingerprinting as a conditional parameter generation task. By leveraging a specialized generator, P2F maps textual descriptions directly to low-rank parameter increments in a single forward pass, enabling plug-and-play LLM fingerprint injection without further model retraining. Our experiments demonstrate that P2F maintains high fingerprint accuracy, harmlessness, and robustness while significantly reducing computational overhead, offering a scalable and instant solution for LLM ownership management.

CPC-VAR:Continual Personalized and Compositional Generation in Visual Autoregressive Models

Visual autoregressive (VAR) models have recently emerged as an efficient paradigm for text-to-image generation. Despite their strong generative capability, existing VAR-based personalization methods remain limited to static settings, failing to accommodate evolving user demands. In particular, sequential concept learning leads to severe catastrophic forgetting, while multi-concept synthesis often suffers from feature entanglement and attribute inconsistency. In this work, we present the first systematic study of continual personalized generation in VAR models. We identify two key challenges: (i) preserving previously learned concepts during sequential customization, and (ii) composing multiple personalized concepts in a controllable manner. To address these issues, we propose a unified framework with two core components. For continual single-concept learning, we introduce Gradient-based Concept Neuron Selection (GCNS), which identifies concept-relevant neurons and constrains only conflicting parameters across tasks, effectively mitigating forgetting without additional model expansion. For multi-concept synthesis, we propose a context-aware composition strategy that performs multi-branch feature modeling and localized cross-attention fusion guided by spatial conditions, enabling precise and disentangled concept composition. Extensive experiments demonstrate that our method significantly improves performance in long-sequence continual personalization while achieving superior results in multi-concept image synthesis compared to existing baselines. These findings highlight the potential of VAR models for scalable and controllable personalized generation.

Mistletoe: Stealthy Acceleration-Collapse Attacks on Speculative Decoding

Speculative decoding has become a widely adopted technique for accelerating large language model (LLM) inference by drafting multiple candidate tokens and verifying them with a target model in parallel. Its efficiency, however, critically depends on the average accepted length $τ$, i.e., how many draft tokens survive each verification step. In this work, we identify a new mechanism-level vulnerability in model-based speculative decoding: the drafter is trained to approximate the target model distribution, but this approximation is inevitably imperfect. Such a drafter-target mismatch creates a hidden attack surface where small perturbations can preserve the target model's visible behavior while substantially reducing draft-token acceptability. We propose Mistletoe, a stealthy acceleration-collapse attack against speculative decoding. Mistletoe directly targets the acceptance mechanism of speculative decoding. It jointly optimizes a degradation objective that decreases drafter-target agreement and a semantic-preservation objective that constrains the target model's output distribution. To resolve the conflict between these objectives, we introduce a null-space projection mechanism, where degradation gradients are projected away from the local semantic-preserving direction, suppressing draft acceptance while minimizing semantic drift. Experiments on various speculative decoding systems show that Mistletoe substantially reduces average accepted length $τ$, collapses speedup, and lowers averaged token throughput, while preserving output quality and perplexity. Our work highlights that speculative decoding introduces a mechanism-level attack surface beyond existing output robustness, calling for more robust designs of LLM acceleration systems.

IndustryBench: Probing the Industrial Knowledge Boundaries of LLMs

In industrial procurement, an LLM answer is useful only if it survives a standards check: recommended material must match operating condition, every parameter must respect a regulated threshold, and no procedure may contradict a safety clause. Partial correctness can mask safety-critical contradictions that aggregate LLM benchmarks rarely capture. We introduce IndustryBench, a 2,049-item benchmark for industrial procurement QA in Chinese, grounded in Chinese national standards (GB/T) and structured industrial product records, organized by seven capability dimensions, ten industry categories, and panel-derived difficulty tiers, with item-aligned English, Russian, and Vietnamese renderings. Our construction pipeline rejects 70.3% of LLM-generated candidates at a search-based external-verification stage, calibrating how unreliable industrial QA remains after LLM-only filtering.Our evaluation decouples raw correctness, scored by a Qwen3-Max judge validated at $κ_w = 0.798$ against a domain expert, from a separate safety-violation (SV) check against source texts. Across 17 models in Chinese and an 8-model intersection over four languages, we find: (i) the best system reaches only 2.083 on the 0--3 rubric, leaving substantial headroom; (ii) Standards & Terminology is the most persistent capability weakness and survives item-aligned translation; (iii) extended reasoning lowers safety-adjusted scores for 12 of 13 models, primarily by introducing unsupported safety-critical details into longer final answers; and (iv) safety-violation rates reshuffle the leaderboard -- GPT-5.4 climbs from rank 6 to rank 3 after SV adjustment, while Kimi-k2.5-1T-A32B drops seven positions.Industrial LLM evaluation therefore requires source-grounded, safety-aware diagnosis rather than aggregate accuracy. We release IndustryBench with all prompts, scoring scripts, and dataset documentation.

Reduced-order Neural Modeling with Differentiable Simulation for High-Detail Tactile Perception

Tactile perception is key to dexterous manipulation, yet simulating high-resolution elastomer deformation remains computationally prohibitive. Finite element methods (FEM) deliver high fidelity but demand costly remeshing, while Material Point Methods (MPM) suffer from heavy particle-memory tradeoffs. We propose a {reduced-order neural simulation framework} that couples coarse-grained MPM dynamics with an implicit neural decoder to reconstruct sub-particle tactile details from compact latent states. The framework learns a continuous deformation manifold from paired high- and low-resolution simulations, enabling physically consistent, differentiable inference. Compared to the TacIPC, our method achieves over 65\% faster simulation and {40\% lower memory usage}, while maintaining better geometric fidelity. In tactile rendering and 3D surface reconstruction, our methods further improve accuracy by 25\% and produce realistic depth images and surface mesh within a faster inference speed. These results demonstrate that the proposed reduced-order neural model enables high-detail, physically grounded tactile simulation with substantial efficiency gains for robotic interaction and optimization.