Digital Staining with Knowledge Distillation: A Unified Framework for Unpaired and Paired-But-Misaligned Data

Staining is essential in cell imaging and medical diagnostics but poses significant challenges, including high cost, time consumption, labor intensity, and irreversible tissue alterations. Recent advances in deep learning have enabled digital staining through supervised model training. However, collecting large-scale, perfectly aligned pairs of stained and unstained images remains difficult. In this work, we propose a novel unsupervised deep learning framework for digital cell staining that reduces the need for extensive paired data using knowledge distillation. We explore two training schemes: (1) unpaired and (2) paired-but-misaligned settings. For the unpaired case, we introduce a two-stage pipeline, comprising light enhancement followed by colorization, as a teacher model. Subsequently, we obtain a student staining generator through knowledge distillation with hybrid non-reference losses. To leverage the pixel-wise information between adjacent sections, we further extend to the paired-but-misaligned setting, adding the Learning to Align module to utilize pixel-level information. Experiment results on our dataset demonstrate that our proposed unsupervised deep staining method can generate stained images with more accurate positions and shapes of the cell targets in both settings. Compared with competing methods, our method achieves improved results both qualitatively and quantitatively (e.g., NIQE and PSNR).We applied our digital staining method to the White Blood Cell (WBC) dataset, investigating its potential for medical applications.

Training-Free Text-Guided Image Editing with Visual Autoregressive Model

Text-guided image editing is an essential task that enables users to modify images through natural language descriptions. Recent advances in diffusion models and rectified flows have significantly improved editing quality, primarily relying on inversion techniques to extract structured noise from input images. However, inaccuracies in inversion can propagate errors, leading to unintended modifications and compromising fidelity. Moreover, even with perfect inversion, the entanglement between textual prompts and image features often results in global changes when only local edits are intended. To address these challenges, we propose a novel text-guided image editing framework based on VAR (Visual AutoRegressive modeling), which eliminates the need for explicit inversion while ensuring precise and controlled modifications. Our method introduces a caching mechanism that stores token indices and probability distributions from the original image, capturing the relationship between the source prompt and the image. Using this cache, we design an adaptive fine-grained masking strategy that dynamically identifies and constrains modifications to relevant regions, preventing unintended changes. A token reassembling approach further refines the editing process, enhancing diversity, fidelity, and control. Our framework operates in a training-free manner and achieves high-fidelity editing with faster inference speeds, processing a 1K resolution image in as fast as 1.2 seconds. Extensive experiments demonstrate that our method achieves performance comparable to, or even surpassing, existing diffusion- and rectified flow-based approaches in both quantitative metrics and visual quality. The code will be released.

Reconciling Stochastic and Deterministic Strategies for Zero-shot Image Restoration using Diffusion Model in Dual

Plug-and-play (PnP) methods offer an iterative strategy for solving image restoration (IR) problems in a zero-shot manner, using a learned \textit{discriminative denoiser} as the implicit prior. More recently, a sampling-based variant of this approach, which utilizes a pre-trained \textit{generative diffusion model}, has gained great popularity for solving IR problems through stochastic sampling. The IR results using PnP with a pre-trained diffusion model demonstrate distinct advantages compared to those using discriminative denoisers, \ie improved perceptual quality while sacrificing the data fidelity. The unsatisfactory results are due to the lack of integration of these strategies in the IR tasks. In this work, we propose a novel zero-shot IR scheme, dubbed Reconciling Diffusion Model in Dual (RDMD), which leverages only a \textbf{single} pre-trained diffusion model to construct \textbf{two} complementary regularizers. Specifically, the diffusion model in RDMD will iteratively perform deterministic denoising and stochastic sampling, aiming to achieve high-fidelity image restoration with appealing perceptual quality. RDMD also allows users to customize the distortion-perception tradeoff with a single hyperparameter, enhancing the adaptability of the restoration process in different practical scenarios. Extensive experiments on several IR tasks demonstrate that our proposed method could achieve superior results compared to existing approaches on both the FFHQ and ImageNet datasets.

Triply Laplacian Scale Mixture Modeling for Seismic Data Noise Suppression

Sparsity-based tensor recovery methods have shown great potential in suppressing seismic data noise. These methods exploit tensor sparsity measures capturing the low-dimensional structures inherent in seismic data tensors to remove noise by applying sparsity constraints through soft-thresholding or hard-thresholding operators. However, in these methods, considering that real seismic data are non-stationary and affected by noise, the variances of tensor coefficients are unknown and may be difficult to accurately estimate from the degraded seismic data, leading to undesirable noise suppression performance. In this paper, we propose a novel triply Laplacian scale mixture (TLSM) approach for seismic data noise suppression, which significantly improves the estimation accuracy of both the sparse tensor coefficients and hidden scalar parameters. To make the optimization problem manageable, an alternating direction method of multipliers (ADMM) algorithm is employed to solve the proposed TLSM-based seismic data noise suppression problem. Extensive experimental results on synthetic and field seismic data demonstrate that the proposed TLSM algorithm outperforms many state-of-the-art seismic data noise suppression methods in both quantitative and qualitative evaluations while providing exceptional computational efficiency.

Towards Robust and Reliable Concept Representations: Reliability-Enhanced Concept Embedding Model

Concept Bottleneck Models (CBMs) aim to enhance interpretability by predicting human-understandable concepts as intermediates for decision-making. However, these models often face challenges in ensuring reliable concept representations, which can propagate to downstream tasks and undermine robustness, especially under distribution shifts. Two inherent issues contribute to concept unreliability: sensitivity to concept-irrelevant features (e.g., background variations) and lack of semantic consistency for the same concept across different samples. To address these limitations, we propose the Reliability-Enhanced Concept Embedding Model (RECEM), which introduces a two-fold strategy: Concept-Level Disentanglement to separate irrelevant features from concept-relevant information and a Concept Mixup mechanism to ensure semantic alignment across samples. These mechanisms work together to improve concept reliability, enabling the model to focus on meaningful object attributes and generate faithful concept representations. Experimental results demonstrate that RECEM consistently outperforms existing baselines across multiple datasets, showing superior performance under background and domain shifts. These findings highlight the effectiveness of disentanglement and alignment strategies in enhancing both reliability and robustness in CBMs.

On the Adversarial Vulnerabilities of Transfer Learning in Remote Sensing

The use of pretrained models from general computer vision tasks is widespread in remote sensing, significantly reducing training costs and improving performance. However, this practice also introduces vulnerabilities to downstream tasks, where publicly available pretrained models can be used as a proxy to compromise downstream models. This paper presents a novel Adversarial Neuron Manipulation method, which generates transferable perturbations by selectively manipulating single or multiple neurons in pretrained models. Unlike existing attacks, this method eliminates the need for domain-specific information, making it more broadly applicable and efficient. By targeting multiple fragile neurons, the perturbations achieve superior attack performance, revealing critical vulnerabilities in deep learning models. Experiments on diverse models and remote sensing datasets validate the effectiveness of the proposed method. This low-access adversarial neuron manipulation technique highlights a significant security risk in transfer learning models, emphasizing the urgent need for more robust defenses in their design when addressing the safety-critical remote sensing tasks.

Discovering Hidden Visual Concepts Beyond Linguistic Input in Infant Learning

Infants develop complex visual understanding rapidly, even preceding of the acquisition of linguistic inputs. As computer vision seeks to replicate the human vision system, understanding infant visual development may offer valuable insights. In this paper, we present an interdisciplinary study exploring this question: can a computational model that imitates the infant learning process develop broader visual concepts that extend beyond the vocabulary it has heard, similar to how infants naturally learn? To investigate this, we analyze a recently published model in Science by Vong et al.,which is trained on longitudinal, egocentric images of a single child paired with transcribed parental speech. We introduce a training-free framework that can discover visual concept neurons hidden in the model's internal representations. Our findings show that these neurons can classify objects outside its original vocabulary. Furthermore, we compare the visual representations in infant-like models with those in moder computer vision models, such as CLIP or ImageNet pre-trained model, highlighting key similarities and differences. Ultimately, our work bridges cognitive science and computer vision by analyzing the internal representations of a computational model trained on an infant's visual and linguistic inputs.

ZoRI: Towards Discriminative Zero-Shot Remote Sensing Instance Segmentation

Instance segmentation algorithms in remote sensing are typically based on conventional methods, limiting their application to seen scenarios and closed-set predictions. In this work, we propose a novel task called zero-shot remote sensing instance segmentation, aimed at identifying aerial objects that are absent from training data. Challenges arise when classifying aerial categories with high inter-class similarity and intra-class variance. Besides, the domain gap between vision-language models' pretraining datasets and remote sensing datasets hinders the zero-shot capabilities of the pretrained model when it is directly applied to remote sensing images. To address these challenges, we propose a $\textbf{Z}$ero-Sh$\textbf{o}$t $\textbf{R}$emote Sensing $\textbf{I}$nstance Segmentation framework, dubbed $\textbf{ZoRI}$. Our approach features a discrimination-enhanced classifier that uses refined textual embeddings to increase the awareness of class disparities. Instead of direct fine-tuning, we propose a knowledge-maintained adaptation strategy that decouples semantic-related information to preserve the pretrained vision-language alignment while adjusting features to capture remote sensing domain-specific visual cues. Additionally, we introduce a prior-injected prediction with cache bank of aerial visual prototypes to supplement the semantic richness of text embeddings and seamlessly integrate aerial representations, adapting to the remote sensing domain. We establish new experimental protocols and benchmarks, and extensive experiments convincingly demonstrate that ZoRI achieves the state-of-art performance on the zero-shot remote sensing instance segmentation task. Our code is available at https://github.com/HuangShiqi128/ZoRI.

Video Set Distillation: Information Diversification and Temporal Densification

The rapid development of AI models has led to a growing emphasis on enhancing their capabilities for complex input data such as videos. While large-scale video datasets have been introduced to support this growth, the unique challenges of reducing redundancies in video \textbf{sets} have not been explored. Compared to image datasets or individual videos, video \textbf{sets} have a two-layer nested structure, where the outer layer is the collection of individual videos, and the inner layer contains the correlations among frame-level data points to provide temporal information. Video \textbf{sets} have two dimensions of redundancies: within-sample and inter-sample redundancies. Existing methods like key frame selection, dataset pruning or dataset distillation are not addressing the unique challenge of video sets since they aimed at reducing redundancies in only one of the dimensions. In this work, we are the first to study Video Set Distillation, which synthesizes optimized video data by jointly addressing within-sample and inter-sample redundancies. Our Information Diversification and Temporal Densification (IDTD) method jointly reduces redundancies across both dimensions. This is achieved through a Feature Pool and Feature Selectors mechanism to preserve inter-sample diversity, alongside a Temporal Fusor that maintains temporal information density within synthesized videos. Our method achieves state-of-the-art results in Video Dataset Distillation, paving the way for more effective redundancy reduction and efficient AI model training on video datasets.

Temporal As a Plugin: Unsupervised Video Denoising with Pre-Trained Image Denoisers

Recent advancements in deep learning have shown impressive results in image and video denoising, leveraging extensive pairs of noisy and noise-free data for supervision. However, the challenge of acquiring paired videos for dynamic scenes hampers the practical deployment of deep video denoising techniques. In contrast, this obstacle is less pronounced in image denoising, where paired data is more readily available. Thus, a well-trained image denoiser could serve as a reliable spatial prior for video denoising. In this paper, we propose a novel unsupervised video denoising framework, named ``Temporal As a Plugin'' (TAP), which integrates tunable temporal modules into a pre-trained image denoiser. By incorporating temporal modules, our method can harness temporal information across noisy frames, complementing its power of spatial denoising. Furthermore, we introduce a progressive fine-tuning strategy that refines each temporal module using the generated pseudo clean video frames, progressively enhancing the network's denoising performance. Compared to other unsupervised video denoising methods, our framework demonstrates superior performance on both sRGB and raw video denoising datasets.