A Contrastive Pretrain Model with Prompt Tuning for Multi-center Medication Recommendation

Medication recommendation is one of the most critical health-related applications, which has attracted extensive research interest recently. Most existing works focus on a single hospital with abundant medical data. However, many small hospitals only have a few records, which hinders applying existing medication recommendation works to the real world. Thus, we seek to explore a more practical setting, i.e., multi-center medication recommendation. In this setting, most hospitals have few records, but the total number of records is large. Though small hospitals may benefit from total affluent records, it is also faced with the challenge that the data distributions between various hospitals are much different. In this work, we introduce a novel conTrastive prEtrain Model with Prompt Tuning (TEMPT) for multi-center medication recommendation, which includes two stages of pretraining and finetuning. We first design two self-supervised tasks for the pretraining stage to learn general medical knowledge. They are mask prediction and contrastive tasks, which extract the intra- and inter-relationships of input diagnosis and procedures. Furthermore, we devise a novel prompt tuning method to capture the specific information of each hospital rather than adopting the common finetuning. On the one hand, the proposed prompt tuning can better learn the heterogeneity of each hospital to fit various distributions. On the other hand, it can also relieve the catastrophic forgetting problem of finetuning. To validate the proposed model, we conduct extensive experiments on the public eICU, a multi-center medical dataset. The experimental results illustrate the effectiveness of our model. The implementation code is available to ease the reproducibility https://github.com/Applied-Machine-Learning-Lab/TEMPT.

Focusing Image Generation to Mitigate Spurious Correlations

Instance features in images exhibit spurious correlations with background features, affecting the training process of deep neural classifiers. This leads to insufficient attention to instance features by the classifier, resulting in erroneous classification outcomes. In this paper, we propose a data augmentation method called Spurious Correlations Guided Synthesis (SCGS) that mitigates spurious correlations through image generation model. This approach does not require expensive spurious attribute (group) labels for the training data and can be widely applied to other debiasing methods. Specifically, SCGS first identifies the incorrect attention regions of a pre-trained classifier on the training images, and then uses an image generation model to generate new training data based on these incorrect attended regions. SCGS increases the diversity and scale of the dataset to reduce the impact of spurious correlations on classifiers. Changes in the classifier's attention regions and experimental results on three different domain datasets demonstrate that this method is effective in reducing the classifier's reliance on spurious correlations.

Multifaceted User Modeling in Recommendation: A Federated Foundation Models Approach

Multifaceted user modeling aims to uncover fine-grained patterns and learn representations from user data, revealing their diverse interests and characteristics, such as profile, preference, and personality. Recent studies on foundation model-based recommendation have emphasized the Transformer architecture's remarkable ability to capture complex, non-linear user-item interaction relationships. This paper aims to advance foundation model-based recommendersystems by introducing enhancements to multifaceted user modeling capabilities. We propose a novel Transformer layer designed specifically for recommendation, using the self-attention mechanism to capture sequential user-item interaction patterns. Specifically, we design a group gating network to identify user groups, enabling hierarchical discovery across different layers, thereby capturing the multifaceted nature of user interests through multiple Transformer layers. Furthermore, to broaden the data scope and further enhance multifaceted user modeling, we extend the framework to a federated setting, enabling the use of private datasets while ensuring privacy. Experimental validations on benchmark datasets demonstrate the superior performance of our proposed method. Code is available.

LLM-Powered User Simulator for Recommender System

User simulators can rapidly generate a large volume of timely user behavior data, providing a testing platform for reinforcement learning-based recommender systems, thus accelerating their iteration and optimization. However, prevalent user simulators generally suffer from significant limitations, including the opacity of user preference modeling and the incapability of evaluating simulation accuracy. In this paper, we introduce an LLM-powered user simulator to simulate user engagement with items in an explicit manner, thereby enhancing the efficiency and effectiveness of reinforcement learning-based recommender systems training. Specifically, we identify the explicit logic of user preferences, leverage LLMs to analyze item characteristics and distill user sentiments, and design a logical model to imitate real human engagement. By integrating a statistical model, we further enhance the reliability of the simulation, proposing an ensemble model that synergizes logical and statistical insights for user interaction simulations. Capitalizing on the extensive knowledge and semantic generation capabilities of LLMs, our user simulator faithfully emulates user behaviors and preferences, yielding high-fidelity training data that enrich the training of recommendation algorithms. We establish quantifying and qualifying experiments on five datasets to validate the simulator's effectiveness and stability across various recommendation scenarios.

Large Language Model Enhanced Recommender Systems: Taxonomy, Trend, Application and Future

Large Language Model (LLM) has transformative potential in various domains, including recommender systems (RS). There have been a handful of research that focuses on empowering the RS by LLM. However, previous efforts mainly focus on LLM as RS, which may face the challenge of intolerant inference costs by LLM. Recently, the integration of LLM into RS, known as LLM-Enhanced Recommender Systems (LLMERS), has garnered significant interest due to its potential to address latency and memory constraints in real-world applications. This paper presents a comprehensive survey of the latest research efforts aimed at leveraging LLM to enhance RS capabilities. We identify a critical shift in the field with the move towards incorporating LLM into the online system, notably by avoiding their use during inference. Our survey categorizes the existing LLMERS approaches into three primary types based on the component of the RS model being augmented: Knowledge Enhancement, Interaction Enhancement, and Model Enhancement. We provide an in-depth analysis of each category, discussing the methodologies, challenges, and contributions of recent studies. Furthermore, we highlight several promising research directions that could further advance the field of LLMERS.

Agents for self-driving laboratories applied to quantum computing

Fully automated self-driving laboratories are promising to enable high-throughput and large-scale scientific discovery by reducing repetitive labour. However, effective automation requires deep integration of laboratory knowledge, which is often unstructured, multimodal, and difficult to incorporate into current AI systems. This paper introduces the k-agents framework, designed to support experimentalists in organizing laboratory knowledge and automating experiments with agents. Our framework employs large language model-based agents to encapsulate laboratory knowledge including available laboratory operations and methods for analyzing experiment results. To automate experiments, we introduce execution agents that break multi-step experimental procedures into state machines, interact with other agents to execute each step and analyze the experiment results. The analyzed results are then utilized to drive state transitions, enabling closed-loop feedback control. To demonstrate its capabilities, we applied the agents to calibrate and operate a superconducting quantum processor, where they autonomously planned and executed experiments for hours, successfully producing and characterizing entangled quantum states at the level achieved by human scientists. Our knowledge-based agent system opens up new possibilities for managing laboratory knowledge and accelerating scientific discovery.

HunyuanVideo: A Systematic Framework For Large Video Generative Models

Recent advancements in video generation have significantly impacted daily life for both individuals and industries. However, the leading video generation models remain closed-source, resulting in a notable performance gap between industry capabilities and those available to the public. In this report, we introduce HunyuanVideo, an innovative open-source video foundation model that demonstrates performance in video generation comparable to, or even surpassing, that of leading closed-source models. HunyuanVideo encompasses a comprehensive framework that integrates several key elements, including data curation, advanced architectural design, progressive model scaling and training, and an efficient infrastructure tailored for large-scale model training and inference. As a result, we successfully trained a video generative model with over 13 billion parameters, making it the largest among all open-source models. We conducted extensive experiments and implemented a series of targeted designs to ensure high visual quality, motion dynamics, text-video alignment, and advanced filming techniques. According to evaluations by professionals, HunyuanVideo outperforms previous state-of-the-art models, including Runway Gen-3, Luma 1.6, and three top-performing Chinese video generative models. By releasing the code for the foundation model and its applications, we aim to bridge the gap between closed-source and open-source communities. This initiative will empower individuals within the community to experiment with their ideas, fostering a more dynamic and vibrant video generation ecosystem. The code is publicly available at https://github.com/Tencent/HunyuanVideo.

GRAPE: Generalizing Robot Policy via Preference Alignment

Despite the recent advancements of vision-language-action (VLA) models on a variety of robotics tasks, they suffer from critical issues such as poor generalizability to unseen tasks, due to their reliance on behavior cloning exclusively from successful rollouts. Furthermore, they are typically fine-tuned to replicate demonstrations collected by experts under different settings, thus introducing distribution bias and limiting their adaptability to diverse manipulation objectives, such as efficiency, safety, and task completion. To bridge this gap, we introduce GRAPE: Generalizing Robot Policy via Preference Alignment. Specifically, GRAPE aligns VLAs on a trajectory level and implicitly models reward from both successful and failure trials to boost generalizability to diverse tasks. Moreover, GRAPE breaks down complex manipulation tasks to independent stages and automatically guides preference modeling through customized spatiotemporal constraints with keypoints proposed by a large vision-language model. Notably, these constraints are flexible and can be customized to align the model with varying objectives, such as safety, efficiency, or task success. We evaluate GRAPE across a diverse array of tasks in both real-world and simulated environments. Experimental results demonstrate that GRAPE enhances the performance of state-of-the-art VLA models, increasing success rates on in-domain and unseen manipulation tasks by 51.79% and 60.36%, respectively. Additionally, GRAPE can be aligned with various objectives, such as safety and efficiency, reducing collision rates by 44.31% and rollout step-length by 11.15%, respectively. All code, models, and data are available at https://grape-vla.github.io/

DISCO: DISCovering Overfittings as Causal Rules for Text Classification Models

With the rapid advancement of neural language models, the deployment of over-parameterized models has surged, increasing the need for interpretable explanations comprehensible to human inspectors. Existing post-hoc interpretability methods, which often focus on unigram features of single input textual instances, fail to capture the models' decision-making process fully. Additionally, many methods do not differentiate between decisions based on spurious correlations and those based on a holistic understanding of the input. Our paper introduces DISCO, a novel method for discovering global, rule-based explanations by identifying causal n-gram associations with model predictions. This method employs a scalable sequence mining technique to extract relevant text spans from training data, associate them with model predictions, and conduct causality checks to distill robust rules that elucidate model behavior. These rules expose potential overfitting and provide insights into misleading feature combinations. We validate DISCO through extensive testing, demonstrating its superiority over existing methods in offering comprehensive insights into complex model behaviors. Our approach successfully identifies all shortcuts manually introduced into the training data (100% detection rate on the MultiRC dataset), resulting in an 18.8% regression in model performance -- a capability unmatched by any other method. Furthermore, DISCO supports interactive explanations, enabling human inspectors to distinguish spurious causes in the rule-based output. This alleviates the burden of abundant instance-wise explanations and helps assess the model's risk when encountering out-of-distribution (OOD) data.

Image Understanding Makes for A Good Tokenizer for Image Generation

Abstract Modern image generation (IG) models have been shown to capture rich semantics valuable for image understanding (IU) tasks. However, the potential of IU models to improve IG performance remains uncharted. We address this issue using a token-based IG framework, which relies on effective tokenizers to project images into token sequences. Currently, pixel reconstruction (e.g., VQGAN) dominates the training objective for image tokenizers. In contrast, our approach adopts the feature reconstruction objective, where tokenizers are trained by distilling knowledge from pretrained IU encoders. Comprehensive comparisons indicate that tokenizers with strong IU capabilities achieve superior IG performance across a variety of metrics, datasets, tasks, and proposal networks. Notably, VQ-KD CLIP achieves $4.10$ FID on ImageNet-1k (IN-1k). Visualization suggests that the superiority of VQ-KD can be partly attributed to the rich semantics within the VQ-KD codebook. We further introduce a straightforward pipeline to directly transform IU encoders into tokenizers, demonstrating exceptional effectiveness for IG tasks. These discoveries may energize further exploration into image tokenizer research and inspire the community to reassess the relationship between IU and IG. The code is released at https://github.com/magic-research/vector_quantization.