A Multi-domain Image Translative Diffusion StyleGAN for Iris Presentation Attack Detection

An iris biometric system can be compromised by presentation attacks (PAs) where artifacts such as artificial eyes, printed eye images, or cosmetic contact lenses are presented to the system. To counteract this, several presentation attack detection (PAD) methods have been developed. However, there is a scarcity of datasets for training and evaluating iris PAD techniques due to the implicit difficulties in constructing and imaging PAs. To address this, we introduce the Multi-domain Image Translative Diffusion StyleGAN (MID-StyleGAN), a new framework for generating synthetic ocular images that captures the PA and bonafide characteristics in multiple domains such as bonafide, printed eyes and cosmetic contact lens. MID-StyleGAN combines the strengths of diffusion models and generative adversarial networks (GANs) to produce realistic and diverse synthetic data. Our approach utilizes a multi-domain architecture that enables the translation between bonafide ocular images and different PA domains. The model employs an adaptive loss function tailored for ocular data to maintain domain consistency. Extensive experiments demonstrate that MID-StyleGAN outperforms existing methods in generating high-quality synthetic ocular images. The generated data was used to significantly enhance the performance of PAD systems, providing a scalable solution to the data scarcity problem in iris and ocular biometrics. For example, on the LivDet2020 dataset, the true detect rate at 1% false detect rate improved from 93.41% to 98.72%, showcasing the impact of the proposed method.

Time-Correlated Video Bridge Matching

Diffusion models excel in noise-to-data generation tasks, providing a mapping from a Gaussian distribution to a more complex data distribution. However they struggle to model translations between complex distributions, limiting their effectiveness in data-to-data tasks. While Bridge Matching (BM) models address this by finding the translation between data distributions, their application to time-correlated data sequences remains unexplored. This is a critical limitation for video generation and manipulation tasks, where maintaining temporal coherence is particularly important. To address this gap, we propose Time-Correlated Video Bridge Matching (TCVBM), a framework that extends BM to time-correlated data sequences in the video domain. TCVBM explicitly models inter-sequence dependencies within the diffusion bridge, directly incorporating temporal correlations into the sampling process. We compare our approach to classical methods based on bridge matching and diffusion models for three video-related tasks: frame interpolation, image-to-video generation, and video super-resolution. TCVBM achieves superior performance across multiple quantitative metrics, demonstrating enhanced generation quality and reconstruction fidelity.

The best performance in the CARE 2025 -- Liver Task (LiSeg-Contrast): Contrast-Aware Semi-Supervised Segmentation with Domain Generalization and Test-Time Adaptation

Accurate liver segmentation from contrast-enhanced MRI is essential for diagnosis, treatment planning, and disease monitoring. However, it remains challenging due to limited annotated data, heterogeneous enhancement protocols, and significant domain shifts across scanners and institutions. Traditional image-to-image translation frameworks have made great progress in domain generalization, but their application is not straightforward. For example, Pix2Pix requires image registration, and cycle-GAN cannot be integrated seamlessly into segmentation pipelines. Meanwhile, these methods are originally used to deal with cross-modality scenarios, and often introduce structural distortions and suffer from unstable training, which may pose drawbacks in our single-modality scenario. To address these challenges, we propose CoSSeg-TTA, a compact segmentation framework for the GED4 (Gd-EOB-DTPA enhanced hepatobiliary phase MRI) modality built upon nnU-Netv2 and enhanced with a semi-supervised mean teacher scheme to exploit large amounts of unlabeled volumes. A domain adaptation module, incorporating a randomized histogram-based style appearance transfer function and a trainable contrast-aware network, enriches domain diversity and mitigates cross-center variability. Furthermore, a continual test-time adaptation strategy is employed to improve robustness during inference. Extensive experiments demonstrate that our framework consistently outperforms the nnU-Netv2 baseline, achieving superior Dice score and Hausdorff Distance while exhibiting strong generalization to unseen domains under low-annotation conditions.

Bidirectional Mammogram View Translation with Column-Aware and Implicit 3D Conditional Diffusion

Dual-view mammography, including craniocaudal (CC) and mediolateral oblique (MLO) projections, offers complementary anatomical views crucial for breast cancer diagnosis. However, in real-world clinical workflows, one view may be missing, corrupted, or degraded due to acquisition errors or compression artifacts, limiting the effectiveness of downstream analysis. View-to-view translation can help recover missing views and improve lesion alignment. Unlike natural images, this task in mammography is highly challenging due to large non-rigid deformations and severe tissue overlap in X-ray projections, which obscure pixel-level correspondences. In this paper, we propose Column-Aware and Implicit 3D Diffusion (CA3D-Diff), a novel bidirectional mammogram view translation framework based on conditional diffusion model. To address cross-view structural misalignment, we first design a column-aware cross-attention mechanism that leverages the geometric property that anatomically corresponding regions tend to lie in similar column positions across views. A Gaussian-decayed bias is applied to emphasize local column-wise correlations while suppressing distant mismatches. Furthermore, we introduce an implicit 3D structure reconstruction module that back-projects noisy 2D latents into a coarse 3D feature volume based on breast-view projection geometry. The reconstructed 3D structure is refined and injected into the denoising UNet to guide cross-view generation with enhanced anatomical awareness. Extensive experiments demonstrate that CA3D-Diff achieves superior performance in bidirectional tasks, outperforming state-of-the-art methods in visual fidelity and structural consistency. Furthermore, the synthesized views effectively improve single-view malignancy classification in screening settings, demonstrating the practical value of our method in real-world diagnostics.

Continual Action Quality Assessment via Adaptive Manifold-Aligned Graph Regularization

Action Quality Assessment (AQA) quantifies human actions in videos, supporting applications in sports scoring, rehabilitation, and skill evaluation. A major challenge lies in the non-stationary nature of quality distributions in real-world scenarios, which limits the generalization ability of conventional methods. We introduce Continual AQA (CAQA), which equips AQA with Continual Learning (CL) capabilities to handle evolving distributions while mitigating catastrophic forgetting. Although parameter-efficient fine-tuning of pretrained models has shown promise in CL for image classification, we find it insufficient for CAQA. Our empirical and theoretical analyses reveal two insights: (i) Full-Parameter Fine-Tuning (FPFT) is necessary for effective representation learning; yet (ii) uncontrolled FPFT induces overfitting and feature manifold shift, thereby aggravating forgetting. To address this, we propose Adaptive Manifold-Aligned Graph Regularization (MAGR++), which couples backbone fine-tuning that stabilizes shallow layers while adapting deeper ones with a two-step feature rectification pipeline: a manifold projector to translate deviated historical features into the current representation space, and a graph regularizer to align local and global distributions. We construct four CAQA benchmarks from three datasets with tailored evaluation protocols and strong baselines, enabling systematic cross-dataset comparison. Extensive experiments show that MAGR++ achieves state-of-the-art performance, with average correlation gains of 3.6% offline and 12.2% online over the strongest baseline, confirming its robustness and effectiveness. Our code is available at https://github.com/ZhouKanglei/MAGRPP.

Multi-Domain Brain Vessel Segmentation Through Feature Disentanglement

The intricate morphology of brain vessels poses significant challenges for automatic segmentation models, which usually focus on a single imaging modality. However, accurately treating brain-related conditions requires a comprehensive understanding of the cerebrovascular tree, regardless of the specific acquisition procedure. Our framework effectively segments brain arteries and veins in various datasets through image-to-image translation while avoiding domain-specific model design and data harmonization between the source and the target domain. This is accomplished by employing disentanglement techniques to independently manipulate different image properties, allowing them to move from one domain to another in a label-preserving manner. Specifically, we focus on manipulating vessel appearances during adaptation while preserving spatial information, such as shapes and locations, which are crucial for correct segmentation. Our evaluation effectively bridges large and varied domain gaps across medical centers, image modalities, and vessel types. Additionally, we conduct ablation studies on the optimal number of required annotations and other architectural choices. The results highlight our framework's robustness and versatility, demonstrating the potential of domain adaptation methodologies to perform cerebrovascular image segmentation in multiple scenarios accurately. Our code is available at https://github.com/i-vesseg/MultiVesSeg.

Clarification as Supervision: Reinforcement Learning for Vision-Language Interfaces

Recent text-only models demonstrate remarkable mathematical reasoning capabilities. Extending these to visual domains requires vision-language models to translate images into text descriptions. However, current models, trained to produce captions for human readers, often omit the precise details that reasoning systems require. This creates an interface mismatch: reasoners often fail not due to reasoning limitations but because they lack access to critical visual information. We propose Adaptive-Clarification Reinforcement Learning (AC-RL), which teaches vision models what information reasoners need through interaction. Our key insight is that clarification requests during training reveal information gaps; by penalizing success that requires clarification, we create pressure for comprehensive initial captions that enable the reasoner to solve the problem in a single pass. AC-RL improves average accuracy by 4.4 points over pretrained baselines across seven visual mathematical reasoning benchmarks, and analysis shows it would cut clarification requests by up to 39% if those were allowed. By treating clarification as a form of implicit supervision, AC-RL demonstrates that vision-language interfaces can be effectively learned through interaction alone, without requiring explicit annotations.

Training-Free Synthetic Data Generation with Dual IP-Adapter Guidance

Few-shot image classification remains challenging due to the limited availability of labeled examples. Recent approaches have explored generating synthetic training data using text-to-image diffusion models, but often require extensive model fine-tuning or external information sources. We present a novel training-free approach, called DIPSY, that leverages IP-Adapter for image-to-image translation to generate highly discriminative synthetic images using only the available few-shot examples. DIPSY introduces three key innovations: (1) an extended classifier-free guidance scheme that enables independent control over positive and negative image conditioning; (2) a class similarity-based sampling strategy that identifies effective contrastive examples; and (3) a simple yet effective pipeline that requires no model fine-tuning or external captioning and filtering. Experiments across ten benchmark datasets demonstrate that our approach achieves state-of-the-art or comparable performance, while eliminating the need for generative model adaptation or reliance on external tools for caption generation and image filtering. Our results highlight the effectiveness of leveraging dual image prompting with positive-negative guidance for generating class-discriminative features, particularly for fine-grained classification tasks.

Transport Based Mean Flows for Generative Modeling

Flow-matching generative models have emerged as a powerful paradigm for continuous data generation, achieving state-of-the-art results across domains such as images, 3D shapes, and point clouds. Despite their success, these models suffer from slow inference due to the requirement of numerous sequential sampling steps. Recent work has sought to accelerate inference by reducing the number of sampling steps. In particular, Mean Flows offer a one-step generation approach that delivers substantial speedups while retaining strong generative performance. Yet, in many continuous domains, Mean Flows fail to faithfully approximate the behavior of the original multi-step flow-matching process. In this work, we address this limitation by incorporating optimal transport-based sampling strategies into the Mean Flow framework, enabling one-step generators that better preserve the fidelity and diversity of the original multi-step flow process. Experiments on controlled low-dimensional settings and on high-dimensional tasks such as image generation, image-to-image translation, and point cloud generation demonstrate that our approach achieves superior inference accuracy in one-step generative modeling.

Deep Learning-Based Cross-Anatomy CT Synthesis Using Adapted nnResU-Net with Anatomical Feature Prioritized Loss

We present a patch-based 3D nnUNet adaptation for MR to CT and CBCT to CT image translation using the multicenter SynthRAD2025 dataset, covering head and neck (HN), thorax (TH), and abdomen (AB) regions. Our approach leverages two main network configurations: a standard UNet and a residual UNet, both adapted from nnUNet for image synthesis. The Anatomical Feature-Prioritized (AFP) loss was introduced, which compares multilayer features extracted from a compact segmentation network trained on TotalSegmentator labels, enhancing reconstruction of clinically relevant structures. Input volumes were normalized per-case using zscore normalization for MRIs, and clipping plus dataset level zscore normalization for CBCT and CT. Training used 3D patches tailored to each anatomical region without additional data augmentation. Models were trained for 1000 and 1500 epochs, with AFP fine-tuning performed for 500 epochs using a combined L1+AFP objective. During inference, overlapping patches were aggregated via mean averaging with step size of 0.3, and postprocessing included reverse zscore normalization. Both network configurations were applied across all regions, allowing consistent model design while capturing local adaptations through residual learning and AFP loss. Qualitative and quantitative evaluation revealed that residual networks combined with AFP yielded sharper reconstructions and improved anatomical fidelity, particularly for bone structures in MR to CT and lesions in CBCT to CT, while L1only networks achieved slightly better intensity-based metrics. This methodology provides a stable solution for cross modality medical image synthesis, demonstrating the effectiveness of combining the automatic nnUNet pipeline with residual learning and anatomically guided feature losses.