Guangdong University of Finance, Guangzhou, China
Abstract:While ubiquitous wearable sensors capture a wealth of behavioral and physiological information, effectively transforming these signals into personalized health insights is challenging. Specifically, converting low-level sensor data into representations capable of characterizing higher-level states is difficult due to high phenotypic diversity and variation in individual baseline health, physiology, and lifestyle factors. Moreover, collecting wearable data paired with health outcome annotations is laborious and expensive, and retrospective annotation remains practically unfeasible, contributing to a scarcity of data with high-quality labels. To overcome these limitations, we propose a foundation model for wearable health that is pretrained on more than one trillion minutes of unlabeled sensor signals drawn from a large cohort of five million participants. We demonstrate that the joint scaling of model capacity and pretraining data volume leads to systematic improvements in performance, as evaluated on a diverse set of 35 health prediction tasks, spanning cardiovascular, metabolic, sleep, and mental health, as well as lifestyle choices and demographic factors. We find that this population scale representation unlocks label-efficient few-shot learning and generative capabilities for robust daily metric estimation. To further leverage this learned representation, we deploy a classroom of LLM agents to autonomously search the space of downstream predictive heads built on the model embeddings, showing broad performance improvements that increase with LLM model capacity. Finally, we show how integrating these downstream predictors into a Personal Health Agent can support model responses that are more relevant, contextually aware, and safe, and we validate this via 1,860 ratings from a cohort of clinicians.
Abstract:Patient-managed Personal Health Records (PHRs) promises to empower patients to better understand their health; but information in the record is complex, potentially hindering insights. In this study, we assess the potential of large language models (LLMs, Gemini 3.0 Flash) to provide helpful answers to user health queries, when provided clinical data from PHRs as context. A total of 2,257 user queries were drawn from 3 different distributions to represent patient questions: shorter web search queries, longer questions derived from templates of chatbot conversations, and questions patients asked to their healthcare team (patient calls). Queries were matched with de-identified PHRs (from a pool of 1,945). Gemini responses were generated (1) without PHR context; (2) with a basic summary of demographics, conditions, and medications; (3) with full, extensive clinical notes. For evaluation, we leveraged an existing rating framework (SHARP), and developed a new framework for specific error modes when interpreting PHRs. Evaluation was performed using autoraters for the full set, and with clinician ratings for a subset (n=95), with both sets of raters knowing the full PHR context. We see significant improvements in the helpfulness of answers to all question types with PHR data (p < 0.001, paired t-test). We also observe potential gains in safety, accuracy, relevance and personalization of answers. Our PHR evaluation framework further identifies gaps in LLM understanding of particular aspects of complex PHRs, such as temporal disorientation, and rare but meaningful confabulations. These results suggest potential for PHR data to help people with a wide range of user needs; and provide a framework for monitoring for gaps in LLM answers based on PHR context. This study motivates further work to assess and realize potential benefits to users from understanding their health records.
Abstract:Few-shot anomaly detection (FSAD) has made significant strides, yet existing methods still face critical challenges: (i) dependence on task- or dataset-specific training/fine-tuning, (ii) reliance on language supervision or carefully hand-crafted prompts, and (iii) limited robustness across domains. In this paper, we introduce HyperFSAD, a novel FSAD framework that is training-free, language-free, and robust across domains, offering a powerful solution to these challenges. Built upon DINOv3 and a hypergraph-based inference mechanism, our approach performs inference without any task-specific optimization or text prompts, while remaining competitive. Specifically, we replace sensitive nearest-neighbor / top-$n$ matching with \textbf{Sparse Hyper Matching}: \textit{sparsemax} first selects the most relevant support patches, which are then aggregated into a \textit{hyperedge} as compact normal evidence to suppress background noise and distractors. We further introduce \textbf{Dual-Branch Image Scoring}, which fuses \emph{spatial anomaly evidence} from the patch-grid anomaly map with \emph{global semantic deviation} captured by support-aware CLS matching, yielding a robust image-level anomaly score in a strictly visual manner. Notably, all components of HyperFSAD are purely visual, eliminating the need for labor-intensive hand-crafted text prompts. Under the stringent training-free and language-free setting, HyperFSAD achieves state-of-the-art performance across six datasets spanning four industrial datasets (MVTecAD, VisA, MPDD, BTAD) and two medical datasets (RESC, BraTS).
Abstract:Language models excel at diagnostic assessments on currated medical case-studies and vignettes, performing on par with, or better than, clinical professionals. However, existing studies focus on complex scenarios with rich context making it difficult to draw conclusions about how these systems perform for patients reporting symptoms in everyday life. We deployed SymptomAI, a set of conversational AI agents for end-to-end patient interviewing and differential diagnosis (DDx), via the Fitbit app in a study that randomized participants (N=13,917) to interact with five AI agents. This corpus captures diverse communication and a realistic distribution of illnesses from a real world population. A subset of 1,228 participants reported a clinician-provided diagnosis, and 517 of these were further evaluated by a panel of clinicians during over 250 hours of annotation. SymptomAI DDx were significantly more accurate (OR = 2.47, p < 0.001) than those from independent clinicians given the same dialogue in a blinded randomized comparison. Moreover, agentic strategies which conduct a dedicated symptom interview that elicit additional symptom information before providing a diagnosis, perform substantially better than baseline, user-guided conversations (p < 0.001). An auxiliary analysis on 1,509 conversations from a general US population panel validated that these results generalize beyond wearable device users. We used SymptomAI diagnoses as labels for all 13,917 participants to analyze over 500,000 days of wearable metrics across nearly 400 unique conditions. We identified strong associations between acute infections and physiological shifts (e.g., OR > 7 for influenza). While limited by self-reported ground truth, these results demonstrate the benefits of a dedicated and complete symptom interview compared to a user-guided symptom discussion, which is the default of most consumer LLMs.
Abstract:Adapting large pretrained models to diverse tasks is now routine, yet the two dominant strategies of parameter-efficient fine-tuning (PEFT) and low-rank compression are typically composed in sequence. This decoupled practice first compresses and then fine-tunes adapters, potentially misaligning the compressed subspace with downstream objectives and squandering a global parameter budget. To overcome this limitation, we introduce JACTUS (Joint Adaptation and Compression with a Task-aware Union of Subspaces), a single framework that unifies compression and adaptation. From a small calibration set, JACTUS estimates input and pre-activation gradient covariances, forms their orthogonal union with the pretrained weight subspace, performs a projected low-rank approximation inside this union, allocates rank globally by marginal gain per parameter, and trains only a compact core matrix. This explicitly mitigates the potential misalignment between the compressed subspace and downstream objectives by coupling the directions preserved for compression with those required for adaptation, yielding a deployable low-rank model that avoids retaining full frozen weights while enabling fast and robust tuning. On vision, JACTUS attains an average 89.2% accuracy on ViT-Base across eight datasets at 80% retained parameters, surpassing strong 100% PEFT baselines (e.g., DoRA 87.9%). On language, JACTUS achieves an 80.9% average on Llama2-7B commonsense QA at the same 80% retained-parameter budget, outperforming 100% PEFT (e.g., DoRA 79.7%) and exceeding prior compress-then-finetune pipelines under the same ratained-parameter budget. We will release code.
Abstract:We introduce MedGemma 1.5 4B, the latest model in the MedGemma collection. MedGemma 1.5 expands on MedGemma 1 by integrating additional capabilities: high-dimensional medical imaging (CT/MRI volumes and histopathology whole slide images), anatomical localization via bounding boxes, multi-timepoint chest X-ray analysis, and improved medical document understanding (lab reports, electronic health records). We detail the innovations required to enable these modalities within a single architecture, including new training data, long-context 3D volume slicing, and whole-slide pathology sampling. Compared to MedGemma 1 4B, MedGemma 1.5 4B demonstrates significant gains in these new areas, improving 3D MRI condition classification accuracy by 11% and 3D CT condition classification by 3% (absolute improvements). In whole slide pathology imaging, MedGemma 1.5 4B achieves a 47% macro F1 gain. Additionally, it improves anatomical localization with a 35% increase in Intersection over Union on chest X-rays and achieves a 4% macro accuracy for longitudinal (multi-timepoint) chest x-ray analysis. Beyond its improved multimodal performance over MedGemma 1, MedGemma 1.5 improves on text-based clinical knowledge and reasoning, improving by 5% on MedQA accuracy and 22% on EHRQA accuracy. It also achieves an average of 18% macro F1 on 4 different lab report information extraction datasets (EHR Datasets 2, 3, 4, and Mendeley Clinical Laboratory Test Reports). Taken together, MedGemma 1.5 serves as a robust, open resource for the community, designed as an improved foundation on which developers can create the next generation of medical AI systems. Resources and tutorials for building upon MedGemma 1.5 can be found at https://goo.gle/MedGemma.
Abstract:This paper presents a comprehensive review of the NTIRE 2026 3D Restoration and Reconstruction (3DRR) Challenge, detailing the proposed methods and results. The challenge seeks to identify robust reconstruction pipelines that are robust under real-world adverse conditions, specifically extreme low-light and smoke-degraded environments, as captured by our RealX3D benchmark. A total of 279 participants registered for the competition, of whom 33 teams submitted valid results. We thoroughly evaluate the submitted approaches against state-of-the-art baselines, revealing significant progress in 3D reconstruction under adverse conditions. Our analysis highlights shared design principles among top-performing methods and provides insights into effective strategies for handling 3D scene degradation.
Abstract:Edge detection is a fundamental image analysis task that underpins numerous high-level vision applications. Recent advances in Transformer architectures have significantly improved edge quality by capturing long-range dependencies, but this often comes with computational overhead. Achieving higher pixel-level accuracy requires increased input resolution, further escalating computational cost and limiting practical deployment. Building on the strong representational capacity of recent Transformer-based edge detectors, we propose an Adaptive Multi-stage non-edge Pruning framework for Edge Detection(Amped). Amped identifies high-confidence non-edge tokens and removes them as early as possible to substantially reduce computation, thus retaining high accuracy while cutting GFLOPs and accelerating inference with minimal performance loss. Moreover, to mitigate the structural complexity of existing edge detection networks and facilitate their integration into real-world systems, we introduce a simple yet high-performance Transformer-based model, termed Streamline Edge Detector(SED). Applied to both existing detectors and our SED, the proposed pruning strategy provides a favorable balance between accuracy and efficiency-reducing GFLOPs by up to 40% with only a 0.4% drop in ODS F-measure. In addition, despite its simplicity, SED achieves a state-of-the-art ODS F-measure of 86.5%. The code will be released.
Abstract:Generalized few-shot semantic segmentation (GFSS) is fundamentally limited by the coverage of novel-class appearances under scarce annotations. While diffusion models can synthesize novel-class images at scale, practical gains are often hindered by insufficient coverage and noisy supervision when masks are unavailable or unreliable. We propose Syn4Seg, a generation-enhanced GFSS framework designed to expand novel-class coverage while improving pseudo-label quality. Syn4Seg first maximizes prompt-space coverage by constructing an embedding-deduplicated prompt bank for each novel class, yielding diverse yet class-consistent synthetic images. It then performs support-guided pseudo-label estimation via a two-stage refinement that i) filters low-consistency regions to obtain high-precision seeds and ii) relabels uncertain pixels with image-adaptive prototypes that combine global (support) and local (image) statistics. Finally, we refine only boundary-band and unlabeled pixels using a constrained SAM-based update to improve contour fidelity without overwriting high-confidence interiors. Extensive experiments on PASCAL-$5^i$ and COCO-$20^i$ demonstrate consistent improvements in both 1-shot and 5-shot settings, highlighting synthetic data as a scalable path for GFSS with reliable masks and precise boundaries.
Abstract:Human athletes demonstrate versatile and highly-dynamic tennis skills to successfully conduct competitive rallies with a high-speed tennis ball. However, reproducing such behaviors on humanoid robots is difficult, partially due to the lack of perfect humanoid action data or human kinematic motion data in tennis scenarios as reference. In this work, we propose LATENT, a system that Learns Athletic humanoid TEnnis skills from imperfect human motioN daTa. The imperfect human motion data consist only of motion fragments that capture the primitive skills used when playing tennis rather than precise and complete human-tennis motion sequences from real-world tennis matches, thereby significantly reducing the difficulty of data collection. Our key insight is that, despite being imperfect, such quasi-realistic data still provide priors about human primitive skills in tennis scenarios. With further correction and composition, we learn a humanoid policy that can consistently strike incoming balls under a wide range of conditions and return them to target locations, while preserving natural motion styles. We also propose a series of designs for robust sim-to-real transfer and deploy our policy on the Unitree G1 humanoid robot. Our method achieves surprising results in the real world and can stably sustain multi-shot rallies with human players. Project page: https://zzk273.github.io/LATENT/