Adversarial Vessel-Unveiling Semi-Supervised Segmentation for Retinopathy of Prematurity Diagnosis

Accurate segmentation of retinal images plays a crucial role in aiding ophthalmologists in diagnosing retinopathy of prematurity (ROP) and assessing its severity. However, due to their underdeveloped, thinner vessels, manual annotation in infant fundus images is very complex, and this presents challenges for fully supervised learning. To address the scarcity of annotations, we propose a semi supervised segmentation framework designed to advance ROP studies without the need for extensive manual vessel annotation. Unlike previous methods that rely solely on limited labeled data, our approach leverages teacher student learning by integrating two powerful components: an uncertainty weighted vessel unveiling module and domain adversarial learning. The vessel unveiling module helps the model effectively reveal obscured and hard to detect vessel structures, while adversarial training aligns feature representations across different domains, ensuring robust and generalizable vessel segmentations. We validate our approach on public datasets (CHASEDB, STARE) and an in-house ROP dataset, demonstrating its superior performance across multiple evaluation metrics. Additionally, we extend the model's utility to a downstream task of ROP multi-stage classification, where vessel masks extracted by our segmentation model improve diagnostic accuracy. The promising results in classification underscore the model's potential for clinical application, particularly in early-stage ROP diagnosis and intervention. Overall, our work offers a scalable solution for leveraging unlabeled data in pediatric ophthalmology, opening new avenues for biomarker discovery and clinical research.

TopoTxR: A topology-guided deep convolutional network for breast parenchyma learning on DCE-MRIs

Characterization of breast parenchyma in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is a challenging task owing to the complexity of underlying tissue structures. Existing quantitative approaches, like radiomics and deep learning models, lack explicit quantification of intricate and subtle parenchymal structures, including fibroglandular tissue. To address this, we propose a novel topological approach that explicitly extracts multi-scale topological structures to better approximate breast parenchymal structures, and then incorporates these structures into a deep-learning-based prediction model via an attention mechanism. Our topology-informed deep learning model, \emph{TopoTxR}, leverages topology to provide enhanced insights into tissues critical for disease pathophysiology and treatment response. We empirically validate \emph{TopoTxR} using the VICTRE phantom breast dataset, showing that the topological structures extracted by our model effectively approximate the breast parenchymal structures. We further demonstrate \emph{TopoTxR}'s efficacy in predicting response to neoadjuvant chemotherapy. Our qualitative and quantitative analyses suggest differential topological behavior of breast tissue in treatment-na\"ive imaging, in patients who respond favorably to therapy as achieving pathological complete response (pCR) versus those who do not. In a comparative analysis with several baselines on the publicly available I-SPY 1 dataset (N=161, including 47 patients with pCR and 114 without) and the Rutgers proprietary dataset (N=120, with 69 patients achieving pCR and 51 not), \emph{TopoTxR} demonstrates a notable improvement, achieving a 2.6\% increase in accuracy and a 4.6\% enhancement in AUC compared to the state-of-the-art method.

MultiPull: Detailing Signed Distance Functions by Pulling Multi-Level Queries at Multi-Step

Reconstructing a continuous surface from a raw 3D point cloud is a challenging task. Recent methods usually train neural networks to overfit on single point clouds to infer signed distance functions (SDFs). However, neural networks tend to smooth local details due to the lack of ground truth signed distances or normals, which limits the performance of overfitting-based methods in reconstruction tasks. To resolve this issue, we propose a novel method, named MultiPull, to learn multi-scale implicit fields from raw point clouds by optimizing accurate SDFs from coarse to fine. We achieve this by mapping 3D query points into a set of frequency features, which makes it possible to leverage multi-level features during optimization. Meanwhile, we introduce optimization constraints from the perspective of spatial distance and normal consistency, which play a key role in point cloud reconstruction based on multi-scale optimization strategies. Our experiments on widely used object and scene benchmarks demonstrate that our method outperforms the state-of-the-art methods in surface reconstruction.

NYC-Event-VPR: A Large-Scale High-Resolution Event-Based Visual Place Recognition Dataset in Dense Urban Environments

Visual place recognition (VPR) enables autonomous robots to identify previously visited locations, which contributes to tasks like simultaneous localization and mapping (SLAM). VPR faces challenges such as accurate image neighbor retrieval and appearance change in scenery. Event cameras, also known as dynamic vision sensors, are a new sensor modality for VPR and offer a promising solution to the challenges with their unique attributes: high temporal resolution (1MHz clock), ultra-low latency (in {\mu}s), and high dynamic range (>120dB). These attributes make event cameras less susceptible to motion blur and more robust in variable lighting conditions, making them suitable for addressing VPR challenges. However, the scarcity of event-based VPR datasets, partly due to the novelty and cost of event cameras, hampers their adoption. To fill this data gap, our paper introduces the NYC-Event-VPR dataset to the robotics and computer vision communities, featuring the Prophesee IMX636 HD event sensor (1280x720 resolution), combined with RGB camera and GPS module. It encompasses over 13 hours of geotagged event data, spanning 260 kilometers across New York City, covering diverse lighting and weather conditions, day/night scenarios, and multiple visits to various locations. Furthermore, our paper employs three frameworks to conduct generalization performance assessments, promoting innovation in event-based VPR and its integration into robotics applications.

Inferring Neural Signed Distance Functions by Overfitting on Single Noisy Point Clouds through Finetuning Data-Driven based Priors

It is important to estimate an accurate signed distance function (SDF) from a point cloud in many computer vision applications. The latest methods learn neural SDFs using either a data-driven based or an overfitting-based strategy. However, these two kinds of methods are with either poor generalization or slow convergence, which limits their capability under challenging scenarios like highly noisy point clouds. To resolve this issue, we propose a method to promote pros of both data-driven based and overfitting-based methods for better generalization, faster inference, and higher accuracy in learning neural SDFs. We introduce a novel statistical reasoning algorithm in local regions which is able to finetune data-driven based priors without signed distance supervision, clean point cloud, or point normals. This helps our method start with a good initialization, and converge to a minimum in a much faster way. Our numerical and visual comparisons with the state-of-the-art methods show our superiority over these methods in surface reconstruction and point cloud denoising on widely used shape and scene benchmarks. The code is available at https://github.com/chenchao15/LocalN2NM.

TopoDiffusionNet: A Topology-aware Diffusion Model

Diffusion models excel at creating visually impressive images but often struggle to generate images with a specified topology. The Betti number, which represents the number of structures in an image, is a fundamental measure in topology. Yet, diffusion models fail to satisfy even this basic constraint. This limitation restricts their utility in applications requiring exact control, like robotics and environmental modeling. To address this, we propose TopoDiffusionNet (TDN), a novel approach that enforces diffusion models to maintain the desired topology. We leverage tools from topological data analysis, particularly persistent homology, to extract the topological structures within an image. We then design a topology-based objective function to guide the denoising process, preserving intended structures while suppressing noisy ones. Our experiments across four datasets demonstrate significant improvements in topological accuracy. TDN is the first to integrate topology with diffusion models, opening new avenues of research in this area.

A Theoretical Study of Neural Network Expressive Power via Manifold Topology

A prevalent assumption regarding real-world data is that it lies on or close to a low-dimensional manifold. When deploying a neural network on data manifolds, the required size, i.e., the number of neurons of the network, heavily depends on the intricacy of the underlying latent manifold. While significant advancements have been made in understanding the geometric attributes of manifolds, it's essential to recognize that topology, too, is a fundamental characteristic of manifolds. In this study, we investigate network expressive power in terms of the latent data manifold. Integrating both topological and geometric facets of the data manifold, we present a size upper bound of ReLU neural networks.

BestMan: A Modular Mobile Manipulator Platform for Embodied AI with Unified Simulation-Hardware APIs

Embodied Artificial Intelligence (Embodied AI) emphasizes agents' ability to perceive, understand, and act in physical environments. Simulation platforms play a crucial role in advancing this field by enabling the validation and optimization of algorithms. However, existing platforms face challenges such as multilevel technical integration complexity, insufficient modularity, interface heterogeneity, and adaptation to diverse hardware. We present BestMan, a simulation platform based on PyBullet, designed to address these issues. BestMan introduces an integrated multilevel skill chain for seamless coordination across perception, planning, and control; a highly modular architecture for flexible algorithm integration; unified interfaces for smooth simulation-to-reality transfer; and a hardware-agnostic approach for adapting to various mobile manipulator configurations. These features collectively simplify development and enhance platform expandability, making BestMan a valuable tool for Embodied AI research.

Long-Tailed Backdoor Attack Using Dynamic Data Augmentation Operations

Recently, backdoor attack has become an increasing security threat to deep neural networks and drawn the attention of researchers. Backdoor attacks exploit vulnerabilities in third-party pretrained models during the training phase, enabling them to behave normally for clean samples and mispredict for samples with specific triggers. Existing backdoor attacks mainly focus on balanced datasets. However, real-world datasets often follow long-tailed distributions. In this paper, for the first time, we explore backdoor attack on such datasets. Specifically, we first analyze the influence of data imbalance on backdoor attack. Based on our analysis, we propose an effective backdoor attack named Dynamic Data Augmentation Operation (D$^2$AO). We design D$^2$AO selectors to select operations depending jointly on the class, sample type (clean vs. backdoored) and sample features. Meanwhile, we develop a trigger generator to generate sample-specific triggers. Through simultaneous optimization of the backdoored model and trigger generator, guided by dynamic data augmentation operation selectors, we achieve significant advancements. Extensive experiments demonstrate that our method can achieve the state-of-the-art attack performance while preserving the clean accuracy.

Constructing and Masking Preference Profile with LLMs for Filtering Discomforting Recommendation

Personalized algorithms can inadvertently expose users to discomforting recommendations, potentially triggering negative consequences. The subjectivity of discomfort and the black-box nature of these algorithms make it challenging to effectively identify and filter such content. To address this, we first conducted a formative study to understand users' practices and expectations regarding discomforting recommendation filtering. Then, we designed a Large Language Model (LLM)-based tool named DiscomfortFilter, which constructs an editable preference profile for a user and helps the user express filtering needs through conversation to mask discomforting preferences within the profile. Based on the edited profile, DiscomfortFilter facilitates the discomforting recommendations filtering in a plug-and-play manner, maintaining flexibility and transparency. The constructed preference profile improves LLM reasoning and simplifies user alignment, enabling a 3.8B open-source LLM to rival top commercial models in an offline proxy task. A one-week user study with 24 participants demonstrated the effectiveness of DiscomfortFilter, while also highlighting its potential impact on platform recommendation outcomes. We conclude by discussing the ongoing challenges, highlighting its relevance to broader research, assessing stakeholder impact, and outlining future research directions.