MedM-VL: What Makes a Good Medical LVLM?

Medical image analysis is a fundamental component. As deep learning progresses, the focus has shifted from single-task applications, such as classification and segmentation, to more complex multimodal tasks, including medical visual question answering and report generation. Traditional shallow and task-specific models are increasingly limited in addressing the complexity and scalability required in clinical practice. The emergence of large language models (LLMs) has driven the development of medical Large Vision-Language Models (LVLMs), offering a unified solution for diverse vision-language tasks. In this study, we investigate various architectural designs for medical LVLMs based on the widely adopted LLaVA framework, which follows an encoder-connector-LLM paradigm. We construct two distinct models targeting 2D and 3D modalities, respectively. These models are designed to support both general-purpose medical tasks and domain-specific fine-tuning, thereby serving as effective foundation models. To facilitate reproducibility and further research, we develop a modular and extensible codebase, MedM-VL, and release two LVLM variants: MedM-VL-2D for 2D medical image analysis and MedM-VL-CT-Chest for 3D CT-based applications. The code and models are available at: https://github.com/MSIIP/MedM-VL

Safety is Not Only About Refusal: Reasoning-Enhanced Fine-tuning for Interpretable LLM Safety

Large Language Models (LLMs) are vulnerable to jailbreak attacks that exploit weaknesses in traditional safety alignment, which often relies on rigid refusal heuristics or representation engineering to block harmful outputs. While they are effective for direct adversarial attacks, they fall short of broader safety challenges requiring nuanced, context-aware decision-making. To address this, we propose Reasoning-enhanced Finetuning for interpretable LLM Safety (Rational), a novel framework that trains models to engage in explicit safe reasoning before response. Fine-tuned models leverage the extensive pretraining knowledge in self-generated reasoning to bootstrap their own safety through structured reasoning, internalizing context-sensitive decision-making. Our findings suggest that safety extends beyond refusal, requiring context awareness for more robust, interpretable, and adaptive responses. Reasoning is not only a core capability of LLMs but also a fundamental mechanism for LLM safety. Rational employs reasoning-enhanced fine-tuning, allowing it to reject harmful prompts while providing meaningful and context-aware responses in complex scenarios.

Conformal Prediction with Upper and Lower Bound Models

This paper studies a Conformal Prediction (CP) methodology for building prediction intervals in a regression setting, given only deterministic lower and upper bounds on the target variable. It proposes a new CP mechanism (CPUL) that goes beyond post-processing by adopting a model selection approach over multiple nested interval construction methods. Paradoxically, many well-established CP methods, including CPUL, may fail to provide adequate coverage in regions where the bounds are tight. To remedy this limitation, the paper proposes an optimal thresholding mechanism, OMLT, that adjusts CPUL intervals in tight regions with undercoverage. The combined CPUL-OMLT is validated on large-scale learning tasks where the goal is to bound the optimal value of a parametric optimization problem. The experimental results demonstrate substantial improvements over baseline methods across various datasets.

Your Language Model May Think Too Rigidly: Achieving Reasoning Consistency with Symmetry-Enhanced Training

Large Language Models (LLMs) have demonstrated strong reasoning capabilities across various tasks. However, even minor variations in query phrasing, despite preserving the underlying semantic meaning, can significantly affect their performance. To address this, we focus on enhancing LLMs' awareness of symmetry in query variations and propose syMmetry-ENhanceD (MEND) Data Augmentation, a data-centric approach that improves the model's ability to extract useful information from context. Unlike existing methods that emphasize reasoning chain augmentation, our approach improves model robustness at the knowledge extraction stage through query augmentations, enabling more data-efficient training and stronger generalization to Out-of-Distribution (OOD) settings. Extensive experiments on both logical and arithmetic reasoning tasks show that MEND enhances reasoning performance across diverse query variations, providing new insight into improving LLM robustness through structured dataset curation.

Connector-S: A Survey of Connectors in Multi-modal Large Language Models

With the rapid advancements in multi-modal large language models (MLLMs), connectors play a pivotal role in bridging diverse modalities and enhancing model performance. However, the design and evolution of connectors have not been comprehensively analyzed, leaving gaps in understanding how these components function and hindering the development of more powerful connectors. In this survey, we systematically review the current progress of connectors in MLLMs and present a structured taxonomy that categorizes connectors into atomic operations (mapping, compression, mixture of experts) and holistic designs (multi-layer, multi-encoder, multi-modal scenarios), highlighting their technical contributions and advancements. Furthermore, we discuss several promising research frontiers and challenges, including high-resolution input, dynamic compression, guide information selection, combination strategy, and interpretability. This survey is intended to serve as a foundational reference and a clear roadmap for researchers, providing valuable insights into the design and optimization of next-generation connectors to enhance the performance and adaptability of MLLMs.

Grade Inflation in Generative Models

Generative models hold great potential, but only if one can trust the evaluation of the data they generate. We show that many commonly used quality scores for comparing two-dimensional distributions of synthetic vs. ground-truth data give better results than they should, a phenomenon we call the "grade inflation problem." We show that the correlation score, Jaccard score, earth-mover's score, and Kullback-Leibler (relative-entropy) score all suffer grade inflation. We propose that any score that values all datapoints equally, as these do, will also exhibit grade inflation; we refer to such scores as "equipoint" scores. We introduce the concept of "equidensity" scores, and present the Eden score, to our knowledge the first example of such a score. We found that Eden avoids grade inflation and agrees better with human perception of goodness-of-fit than the equipoint scores above. We propose that any reasonable equidensity score will avoid grade inflation. We identify a connection between equidensity scores and R\'enyi entropy of negative order. We conclude that equidensity scores are likely to outperform equipoint scores for generative models, and for comparing low-dimensional distributions more generally.

Rethinking the Intermediate Features in Adversarial Attacks: Misleading Robotic Models via Adversarial Distillation

Language-conditioned robotic learning has significantly enhanced robot adaptability by enabling a single model to execute diverse tasks in response to verbal commands. Despite these advancements, security vulnerabilities within this domain remain largely unexplored. This paper addresses this gap by proposing a novel adversarial prompt attack tailored to language-conditioned robotic models. Our approach involves crafting a universal adversarial prefix that induces the model to perform unintended actions when added to any original prompt. We demonstrate that existing adversarial techniques exhibit limited effectiveness when directly transferred to the robotic domain due to the inherent robustness of discretized robotic action spaces. To overcome this challenge, we propose to optimize adversarial prefixes based on continuous action representations, circumventing the discretization process. Additionally, we identify the beneficial impact of intermediate features on adversarial attacks and leverage the negative gradient of intermediate self-attention features to further enhance attack efficacy. Extensive experiments on VIMA models across 13 robot manipulation tasks validate the superiority of our method over existing approaches and demonstrate its transferability across different model variants.

Med-2E3: A 2D-Enhanced 3D Medical Multimodal Large Language Model

The analysis of 3D medical images is crucial for modern healthcare, yet traditional task-specific models are becoming increasingly inadequate due to limited generalizability across diverse clinical scenarios. Multimodal large language models (MLLMs) offer a promising solution to these challenges. However, existing MLLMs have limitations in fully leveraging the rich, hierarchical information embedded in 3D medical images. Inspired by clinical practice, where radiologists focus on both 3D spatial structure and 2D planar content, we propose Med-2E3, a novel MLLM for 3D medical image analysis that integrates 3D and 2D encoders. To aggregate 2D features more effectively, we design a Text-Guided Inter-Slice (TG-IS) scoring module, which scores the attention of each 2D slice based on slice contents and task instructions. To the best of our knowledge, Med-2E3 is the first MLLM to integrate both 3D and 2D features for 3D medical image analysis. Experiments on a large-scale, open-source 3D medical multimodal benchmark demonstrate that Med-2E3 exhibits task-specific attention distribution and significantly outperforms current state-of-the-art models, with a 14% improvement in report generation and a 5% gain in medical visual question answering (VQA), highlighting the model's potential in addressing complex multimodal clinical tasks. The code will be released upon acceptance.

Learning Robust Grasping Strategy Through Tactile Sensing and Adaption Skill

Robust grasping represents an essential task in robotics, necessitating tactile feedback and reactive grasping adjustments for robust grasping of objects. Previous research has extensively combined tactile sensing with grasping, primarily relying on rule-based approaches, frequently neglecting post-grasping difficulties such as external disruptions or inherent uncertainties of the object's physics and geometry. To address these limitations, this paper introduces an human-demonstration-based adaptive grasping policy base on tactile, which aims to achieve robust gripping while resisting disturbances to maintain grasp stability. Our trained model generalizes to daily objects with seven different sizes, shapes, and textures. Experimental results demonstrate that our method performs well in dynamic and force interaction tasks and exhibits excellent generalization ability.

Enhancing elusive clues in knowledge learning by contrasting attention of language models

Causal language models acquire vast amount of knowledge from general text corpus during pretraining, but the efficiency of knowledge learning is known to be unsatisfactory, especially when learning from knowledge-dense and small-sized corpora. The deficiency can come from long-distance dependencies which are hard to capture by language models, and overfitting to co-occurrence patterns and distracting clues in the training text. To address these issues, the paper proposes a method to enhance knowledge learning during language model pretraining, by enhancing elusive but important clues in text discovered by the language model themselves. We found that larger language models pay more attention to non-obvious but important clues, which are often overlooked by smaller language models. Therefore, we can identify these clues by contrasting the attention weights of large and small language models. We use the identified clues as a guide to perform token-dropout data augmentation on the training text, and observed a significant boost in both small and large models' performance in fact memorization. This shows that the behavior contrast between more and less-performant language models contains important clues for knowledge learning, and it can be ``amplified" for a straight-forward improvement in knowledge learning efficiency.