Abstract:In the realm of large-scale point cloud registration, designing a compact symbolic representation is crucial for efficiently processing vast amounts of data, ensuring registration robustness against significant viewpoint variations and occlusions. This paper introduces a novel point cloud registration method, i.e., QuadricsReg, which leverages concise quadrics primitives to represent scenes and utilizes their geometric characteristics to establish correspondences for 6-DoF transformation estimation. As a symbolic feature, the quadric representation fully captures the primary geometric characteristics of scenes, which can efficiently handle the complexity of large-scale point clouds. The intrinsic characteristics of quadrics, such as types and scales, are employed to initialize correspondences. Then we build a multi-level compatibility graph set to find the correspondences using the maximum clique on the geometric consistency between quadrics. Finally, we estimate the 6-DoF transformation using the quadric correspondences, which is further optimized based on the quadric degeneracy-aware distance in a factor graph, ensuring high registration accuracy and robustness against degenerate structures. We test on 5 public datasets and the self-collected heterogeneous dataset across different LiDAR sensors and robot platforms. The exceptional registration success rates and minimal registration errors demonstrate the effectiveness of QuadricsReg in large-scale point cloud registration scenarios. Furthermore, the real-world registration testing on our self-collected heterogeneous dataset shows the robustness and generalization ability of QuadricsReg on different LiDAR sensors and robot platforms. The codes and demos will be released at \url{https://levenberg.github.io/QuadricsReg}.
Abstract:The analysis of 3D medical images is crucial for modern healthcare, yet traditional task-specific models are becoming increasingly inadequate due to limited generalizability across diverse clinical scenarios. Multimodal large language models (MLLMs) offer a promising solution to these challenges. However, existing MLLMs have limitations in fully leveraging the rich, hierarchical information embedded in 3D medical images. Inspired by clinical practice, where radiologists focus on both 3D spatial structure and 2D planar content, we propose Med-2E3, a novel MLLM for 3D medical image analysis that integrates 3D and 2D encoders. To aggregate 2D features more effectively, we design a Text-Guided Inter-Slice (TG-IS) scoring module, which scores the attention of each 2D slice based on slice contents and task instructions. To the best of our knowledge, Med-2E3 is the first MLLM to integrate both 3D and 2D features for 3D medical image analysis. Experiments on a large-scale, open-source 3D medical multimodal benchmark demonstrate that Med-2E3 exhibits task-specific attention distribution and significantly outperforms current state-of-the-art models, with a 14% improvement in report generation and a 5% gain in medical visual question answering (VQA), highlighting the model's potential in addressing complex multimodal clinical tasks. The code will be released upon acceptance.
Abstract:Multi-modal large language models (MLLMs) have shown impressive capabilities as a general-purpose interface for various visual and linguistic tasks. However, building a unified MLLM for multi-task learning in the medical field remains a thorny challenge. To mitigate the tug-of-war problem of multi-modal multi-task optimization, recent advances primarily focus on improving the LLM components, while neglecting the connector that bridges the gap between modalities. In this paper, we introduce Uni-Med, a novel medical generalist foundation model which consists of a universal visual feature extraction module, a connector mixture-of-experts (CMoE) module, and an LLM. Benefiting from the proposed CMoE that leverages a well-designed router with a mixture of projection experts at the connector, Uni-Med achieves efficient solution to the tug-of-war problem and can perform six different medical tasks including question answering, visual question answering, report generation, referring expression comprehension, referring expression generation and image classification. To the best of our knowledge, Uni-Med is the first effort to tackle multi-task interference at the connector. Extensive ablation experiments validate the effectiveness of introducing CMoE under any configuration, with up to an average 8% performance gains. We further provide interpretation analysis of the tug-of-war problem from the perspective of gradient optimization and parameter statistics. Compared to previous state-of-the-art medical MLLMs, Uni-Med achieves competitive or superior evaluation metrics on diverse tasks. Code, data and model will be soon available at GitHub.
Abstract:Causal language models acquire vast amount of knowledge from general text corpus during pretraining, but the efficiency of knowledge learning is known to be unsatisfactory, especially when learning from knowledge-dense and small-sized corpora. The deficiency can come from long-distance dependencies which are hard to capture by language models, and overfitting to co-occurrence patterns and distracting clues in the training text. To address these issues, the paper proposes a method to enhance knowledge learning during language model pretraining, by enhancing elusive but important clues in text discovered by the language model themselves. We found that larger language models pay more attention to non-obvious but important clues, which are often overlooked by smaller language models. Therefore, we can identify these clues by contrasting the attention weights of large and small language models. We use the identified clues as a guide to perform token-dropout data augmentation on the training text, and observed a significant boost in both small and large models' performance in fact memorization. This shows that the behavior contrast between more and less-performant language models contains important clues for knowledge learning, and it can be ``amplified" for a straight-forward improvement in knowledge learning efficiency.
Abstract:In the study, we aim to investigate current LLMs' mastery of medical factual knowledge with a dynamic evaluation schema, which can automatically generate multiple test samples for each medical factual knowledge point. Test samples produced directly by LLMs always introduce factual errors and lack diversity in the manner of knowledge expression. To overcome the drawbacks, here we propose a novel evaluation method, Predicate-text Dual Transformation (PretextTrans), by introducing predicate transformations into the dynamic evaluation schema. Specifically, each medical knowledge point is firstly transformed into a predicate expression; then, the predicate expression derives a series of variants through predicate transformations; lastly, the produced predicate variants are transformed back into textual expressions, resulting in a series of test samples with both factual reliability and expression diversity. Using the proposed PretextTrans method, we systematically investigate 12 well-known LLMs' mastery of medical factual knowledge based on two medical datasets. The comparison results show that current LLMs still have significant deficiencies in fully mastering medical knowledge, which may illustrate why current LLMs still perform unsatisfactorily in real-world medical scenarios despite having achieved considerable performance on public benchmarks. Our proposed method serves as an effective solution for evaluation of LLMs in medical domain and offers valuable insights for developing medical-specific LLMs.
Abstract:Pretrained language models can encode a large amount of knowledge and utilize it for various reasoning tasks, yet they can still struggle to learn novel factual knowledge effectively from finetuning on limited textual demonstrations. In this work, we show that the reason for this deficiency is that language models are biased to learn word co-occurrence statistics instead of true factual associations. We identify the differences between two forms of knowledge representation in language models: knowledge in the form of co-occurrence statistics is encoded in the middle layers of the transformer model and does not generalize well to reasoning scenarios beyond simple question answering, while true factual associations are encoded in the lower layers and can be freely utilized in various reasoning tasks. Based on these observations, we propose two strategies to improve the learning of factual associations in language models. We show that training on text with implicit rather than explicit factual associations can force the model to learn factual associations instead of co-occurrence statistics, significantly improving the generalization of newly learned knowledge. We also propose a simple training method to actively forget the learned co-occurrence statistics, which unblocks and enhances the learning of factual associations when training on plain narrative text. On both synthetic and real-world corpora, the two proposed strategies improve the generalization of the knowledge learned during finetuning to reasoning scenarios such as indirect and multi-hop question answering.
Abstract:Large language models (LLMs) have obtained promising results in mathematical reasoning, which is a foundational skill for human intelligence. Most previous studies focus on improving and measuring the performance of LLMs based on textual math reasoning datasets (e.g., MATH, GSM8K). Recently, a few researchers have released English multimodal math datasets (e.g., MATHVISTA and MATH-V) to evaluate the effectiveness of large multimodal models (LMMs). In this paper, we release a Chinese multimodal math (CMM-Math) dataset, including benchmark and training parts, to evaluate and enhance the mathematical reasoning of LMMs. CMM-Math contains over 28,000 high-quality samples, featuring a variety of problem types (e.g., multiple-choice, fill-in-the-blank, and so on) with detailed solutions across 12 grade levels from elementary to high school in China. Specifically, the visual context may be present in the questions or opinions, which makes this dataset more challenging. Through comprehensive analysis, we discover that state-of-the-art LMMs on the CMM-Math dataset face challenges, emphasizing the necessity for further improvements in LMM development. We also propose a Multimodal Mathematical LMM (Math-LMM) to handle the problems with mixed input of multiple images and text segments. We train our model using three stages, including foundational pre-training, foundational fine-tuning, and mathematical fine-tuning. The extensive experiments indicate that our model effectively improves math reasoning performance by comparing it with the SOTA LMMs over three multimodal mathematical datasets.
Abstract:The early detection of suicide risk is important since it enables the intervention to prevent potential suicide attempts. This paper studies the automatic detection of suicide risk based on spontaneous speech from adolescents, and collects a Mandarin dataset with 15 hours of suicide speech from more than a thousand adolescents aged from ten to eighteen for our experiments. To leverage the diverse acoustic and linguistic features embedded in spontaneous speech, both the Whisper speech model and textual large language models (LLMs) are used for suicide risk detection. Both all-parameter finetuning and parameter-efficient finetuning approaches are used to adapt the pre-trained models for suicide risk detection, and multiple audio-text fusion approaches are evaluated to combine the representations of Whisper and the LLM. The proposed system achieves a detection accuracy of 0.807 and an F1-score of 0.846 on the test set with 119 subjects, indicating promising potential for real suicide risk detection applications.
Abstract:Large language models (LLMs) have excelled across domains, also delivering notable performance on the medical evaluation benchmarks, such as MedQA. However, there still exists a significant gap between the reported performance and the practical effectiveness in real-world medical scenarios. In this paper, we aim to explore the causes of this gap by employing a multifaceted examination schema to systematically probe the actual mastery of medical knowledge by current LLMs. Specifically, we develop a novel evaluation framework MultifacetEval to examine the degree and coverage of LLMs in encoding and mastering medical knowledge at multiple facets (comparison, rectification, discrimination, and verification) concurrently. Based on the MultifacetEval framework, we construct two multifaceted evaluation datasets: MultiDiseK (by producing questions from a clinical disease knowledge base) and MultiMedQA (by rephrasing each question from a medical benchmark MedQA into multifaceted questions). The experimental results on these multifaceted datasets demonstrate that the extent of current LLMs in mastering medical knowledge is far below their performance on existing medical benchmarks, suggesting that they lack depth, precision, and comprehensiveness in mastering medical knowledge. Consequently, current LLMs are not yet ready for application in real-world medical tasks. The codes and datasets are available at https://github.com/THUMLP/MultifacetEval.
Abstract:Language models can learn sophisticated language understanding skills from fitting raw text. They also unselectively learn useless corpus statistics and biases, especially during finetuning on domain-specific corpora. In this paper, we propose a simple modification to causal language modeling called conditional finetuning, which performs language modeling conditioned on a context. We show that a context can "explain away" certain corpus statistics and make the model avoid learning them. In this fashion, conditional finetuning achieves selective learning from a corpus, learning knowledge useful for downstream tasks while avoiding learning useless corpus statistics like topic biases. This selective learning effect leads to less forgetting and better stability-plasticity tradeoff in domain finetuning, potentially benefitting lifelong learning with language models.