Deep Learning-based Automated Diagnosis of Obstructive Sleep Apnea and Sleep Stage Classification in Children Using Millimeter-wave Radar and Pulse Oximeter

Study Objectives: To evaluate the agreement between the millimeter-wave radar-based device and polysomnography (PSG) in diagnosis of obstructive sleep apnea (OSA) and classification of sleep stage in children. Methods: 281 children, aged 1 to 18 years, who underwent sleep monitoring between September and November 2023 at the Sleep Center of Beijing Children's Hospital, Capital Medical University, were recruited in the study. All enrolled children underwent sleep monitoring by PSG and the millimeter-wave radar-based device, QSA600, simultaneously. QSA600 recordings were automatically analyzed using a deep learning model meanwhile the PSG data was manually scored. Results: The Obstructive Apnea-Hypopnea Index (OAHI) obtained from QSA600 and PSG demonstrates a high level of agreement with an intraclass correlation coefficient of 0.945 (95% CI: 0.93 to 0.96). Bland-Altman analysis indicates that the mean difference of OAHI between QSA600 and PSG is -0.10 events/h (95% CI: -11.15 to 10.96). The deep learning model evaluated through cross-validation showed good sensitivity (81.8%, 84.3% and 89.7%) and specificity (90.5%, 95.3% and 97.1%) values for diagnosing children with OAHI>1, OAHI>5 and OAHI>10. The area under the receiver operating characteristic curve is 0.923, 0.955 and 0.988, respectively. For sleep stage classification, the model achieved Kappa coefficients of 0.854, 0.781, and 0.734, with corresponding overall accuracies of 95.0%, 84.8%, and 79.7% for Wake-sleep classification, Wake-REM-Light-Deep classification, and Wake-REM-N1-N2 N3 classification, respectively. Conclusions: QSA600 has demonstrated high agreement with PSG in diagnosing OSA and performing sleep staging in children. The device is portable, low-load and suitable for follow up and long-term pediatric sleep assessment.

Detection of Sleep Apnea-Hypopnea Events Using Millimeter-wave Radar and Pulse Oximeter

Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS) is a sleep-related breathing disorder associated with significant morbidity and mortality worldwide. The gold standard for OSAHS diagnosis, polysomnography (PSG), faces challenges in popularization due to its high cost and complexity. Recently, radar has shown potential in detecting sleep apnea-hypopnea events (SAE) with the advantages of low cost and non-contact monitoring. However, existing studies, especially those using deep learning, employ segment-based classification approach for SAE detection, making the task of event quantity estimation difficult. Additionally, radar-based SAE detection is susceptible to interference from body movements and the environment. Oxygen saturation (SpO2) can offer valuable information about OSAHS, but it also has certain limitations and cannot be used alone for diagnosis. In this study, we propose a method using millimeter-wave radar and pulse oximeter to detect SAE, called ROSA. It fuses information from both sensors, and directly predicts the temporal localization of SAE. Experimental results demonstrate a high degree of consistency (ICC=0.9864) between AHI from ROSA and PSG. This study presents an effective method with low-load device for the diagnosis of OSAHS.

FreeTraj: Tuning-Free Trajectory Control in Video Diffusion Models

Diffusion model has demonstrated remarkable capability in video generation, which further sparks interest in introducing trajectory control into the generation process. While existing works mainly focus on training-based methods (e.g., conditional adapter), we argue that diffusion model itself allows decent control over the generated content without requiring any training. In this study, we introduce a tuning-free framework to achieve trajectory-controllable video generation, by imposing guidance on both noise construction and attention computation. Specifically, 1) we first show several instructive phenomenons and analyze how initial noises influence the motion trajectory of generated content. 2) Subsequently, we propose FreeTraj, a tuning-free approach that enables trajectory control by modifying noise sampling and attention mechanisms. 3) Furthermore, we extend FreeTraj to facilitate longer and larger video generation with controllable trajectories. Equipped with these designs, users have the flexibility to provide trajectories manually or opt for trajectories automatically generated by the LLM trajectory planner. Extensive experiments validate the efficacy of our approach in enhancing the trajectory controllability of video diffusion models.

GaussianCity: Generative Gaussian Splatting for Unbounded 3D City Generation

3D city generation with NeRF-based methods shows promising generation results but is computationally inefficient. Recently 3D Gaussian Splatting (3D-GS) has emerged as a highly efficient alternative for object-level 3D generation. However, adapting 3D-GS from finite-scale 3D objects and humans to infinite-scale 3D cities is non-trivial. Unbounded 3D city generation entails significant storage overhead (out-of-memory issues), arising from the need to expand points to billions, often demanding hundreds of Gigabytes of VRAM for a city scene spanning 10km^2. In this paper, we propose GaussianCity, a generative Gaussian Splatting framework dedicated to efficiently synthesizing unbounded 3D cities with a single feed-forward pass. Our key insights are two-fold: 1) Compact 3D Scene Representation: We introduce BEV-Point as a highly compact intermediate representation, ensuring that the growth in VRAM usage for unbounded scenes remains constant, thus enabling unbounded city generation. 2) Spatial-aware Gaussian Attribute Decoder: We present spatial-aware BEV-Point decoder to produce 3D Gaussian attributes, which leverages Point Serializer to integrate the structural and contextual characteristics of BEV points. Extensive experiments demonstrate that GaussianCity achieves state-of-the-art results in both drone-view and street-view 3D city generation. Notably, compared to CityDreamer, GaussianCity exhibits superior performance with a speedup of 60 times (10.72 FPS v.s. 0.18 FPS).

FashionEngine: Interactive Generation and Editing of 3D Clothed Humans

We present FashionEngine, an interactive 3D human generation and editing system that allows us to design 3D digital humans in a way that aligns with how humans interact with the world, such as natural languages, visual perceptions, and hand-drawing. FashionEngine automates the 3D human production with three key components: 1) A pre-trained 3D human diffusion model that learns to model 3D humans in a semantic UV latent space from 2D image training data, which provides strong priors for diverse generation and editing tasks. 2) Multimodality-UV Space encoding the texture appearance, shape topology, and textual semantics of human clothing in a canonical UV-aligned space, which faithfully aligns the user multimodal inputs with the implicit UV latent space for controllable 3D human editing. The multimodality-UV space is shared across different user inputs, such as texts, images, and sketches, which enables various joint multimodal editing tasks. 3) Multimodality-UV Aligned Sampler learns to sample high-quality and diverse 3D humans from the diffusion prior for multimodal user inputs. Extensive experiments validate FashionEngine's state-of-the-art performance for conditional generation/editing tasks. In addition, we present an interactive user interface for our FashionEngine that enables both conditional and unconditional generation tasks, and editing tasks including pose/view/shape control, text-, image-, and sketch-driven 3D human editing and 3D virtual try-on, in a unified framework. Our project page is at: https://taohuumd.github.io/projects/FashionEngine.

3DTopia: Large Text-to-3D Generation Model with Hybrid Diffusion Priors

We present a two-stage text-to-3D generation system, namely 3DTopia, which generates high-quality general 3D assets within 5 minutes using hybrid diffusion priors. The first stage samples from a 3D diffusion prior directly learned from 3D data. Specifically, it is powered by a text-conditioned tri-plane latent diffusion model, which quickly generates coarse 3D samples for fast prototyping. The second stage utilizes 2D diffusion priors to further refine the texture of coarse 3D models from the first stage. The refinement consists of both latent and pixel space optimization for high-quality texture generation. To facilitate the training of the proposed system, we clean and caption the largest open-source 3D dataset, Objaverse, by combining the power of vision language models and large language models. Experiment results are reported qualitatively and quantitatively to show the performance of the proposed system. Our codes and models are available at https://github.com/3DTopia/3DTopia

LGM: Large Multi-View Gaussian Model for High-Resolution 3D Content Creation

3D content creation has achieved significant progress in terms of both quality and speed. Although current feed-forward models can produce 3D objects in seconds, their resolution is constrained by the intensive computation required during training. In this paper, we introduce Large Multi-View Gaussian Model (LGM), a novel framework designed to generate high-resolution 3D models from text prompts or single-view images. Our key insights are two-fold: 1) 3D Representation: We propose multi-view Gaussian features as an efficient yet powerful representation, which can then be fused together for differentiable rendering. 2) 3D Backbone: We present an asymmetric U-Net as a high-throughput backbone operating on multi-view images, which can be produced from text or single-view image input by leveraging multi-view diffusion models. Extensive experiments demonstrate the high fidelity and efficiency of our approach. Notably, we maintain the fast speed to generate 3D objects within 5 seconds while boosting the training resolution to 512, thereby achieving high-resolution 3D content generation.

URHand: Universal Relightable Hands

Existing photorealistic relightable hand models require extensive identity-specific observations in different views, poses, and illuminations, and face challenges in generalizing to natural illuminations and novel identities. To bridge this gap, we present URHand, the first universal relightable hand model that generalizes across viewpoints, poses, illuminations, and identities. Our model allows few-shot personalization using images captured with a mobile phone, and is ready to be photorealistically rendered under novel illuminations. To simplify the personalization process while retaining photorealism, we build a powerful universal relightable prior based on neural relighting from multi-view images of hands captured in a light stage with hundreds of identities. The key challenge is scaling the cross-identity training while maintaining personalized fidelity and sharp details without compromising generalization under natural illuminations. To this end, we propose a spatially varying linear lighting model as the neural renderer that takes physics-inspired shading as input feature. By removing non-linear activations and bias, our specifically designed lighting model explicitly keeps the linearity of light transport. This enables single-stage training from light-stage data while generalizing to real-time rendering under arbitrary continuous illuminations across diverse identities. In addition, we introduce the joint learning of a physically based model and our neural relighting model, which further improves fidelity and generalization. Extensive experiments show that our approach achieves superior performance over existing methods in terms of both quality and generalizability. We also demonstrate quick personalization of URHand from a short phone scan of an unseen identity.

PrimDiffusion: Volumetric Primitives Diffusion for 3D Human Generation

We present PrimDiffusion, the first diffusion-based framework for 3D human generation. Devising diffusion models for 3D human generation is difficult due to the intensive computational cost of 3D representations and the articulated topology of 3D humans. To tackle these challenges, our key insight is operating the denoising diffusion process directly on a set of volumetric primitives, which models the human body as a number of small volumes with radiance and kinematic information. This volumetric primitives representation marries the capacity of volumetric representations with the efficiency of primitive-based rendering. Our PrimDiffusion framework has three appealing properties: 1) compact and expressive parameter space for the diffusion model, 2) flexible 3D representation that incorporates human prior, and 3) decoder-free rendering for efficient novel-view and novel-pose synthesis. Extensive experiments validate that PrimDiffusion outperforms state-of-the-art methods in 3D human generation. Notably, compared to GAN-based methods, our PrimDiffusion supports real-time rendering of high-quality 3D humans at a resolution of $512\times512$ once the denoising process is done. We also demonstrate the flexibility of our framework on training-free conditional generation such as texture transfer and 3D inpainting.

PERF: Panoramic Neural Radiance Field from a Single Panorama

Neural Radiance Field (NeRF) has achieved substantial progress in novel view synthesis given multi-view images. Recently, some works have attempted to train a NeRF from a single image with 3D priors. They mainly focus on a limited field of view with a few occlusions, which greatly limits their scalability to real-world 360-degree panoramic scenarios with large-size occlusions. In this paper, we present PERF, a 360-degree novel view synthesis framework that trains a panoramic neural radiance field from a single panorama. Notably, PERF allows 3D roaming in a complex scene without expensive and tedious image collection. To achieve this goal, we propose a novel collaborative RGBD inpainting method and a progressive inpainting-and-erasing method to lift up a 360-degree 2D scene to a 3D scene. Specifically, we first predict a panoramic depth map as initialization given a single panorama and reconstruct visible 3D regions with volume rendering. Then we introduce a collaborative RGBD inpainting approach into a NeRF for completing RGB images and depth maps from random views, which is derived from an RGB Stable Diffusion model and a monocular depth estimator. Finally, we introduce an inpainting-and-erasing strategy to avoid inconsistent geometry between a newly-sampled view and reference views. The two components are integrated into the learning of NeRFs in a unified optimization framework and achieve promising results. Extensive experiments on Replica and a new dataset PERF-in-the-wild demonstrate the superiority of our PERF over state-of-the-art methods. Our PERF can be widely used for real-world applications, such as panorama-to-3D, text-to-3D, and 3D scene stylization applications. Project page and code are available at https://perf-project.github.io/ and https://github.com/perf-project/PeRF.