Contrast-Unity for Partially-Supervised Temporal Sentence Grounding

Temporal sentence grounding aims to detect event timestamps described by the natural language query from given untrimmed videos. The existing fully-supervised setting achieves great results but requires expensive annotation costs; while the weakly-supervised setting adopts cheap labels but performs poorly. To pursue high performance with less annotation costs, this paper introduces an intermediate partially-supervised setting, i.e., only short-clip is available during training. To make full use of partial labels, we specially design one contrast-unity framework, with the two-stage goal of implicit-explicit progressive grounding. In the implicit stage, we align event-query representations at fine granularity using comprehensive quadruple contrastive learning: event-query gather, event-background separation, intra-cluster compactness and inter-cluster separability. Then, high-quality representations bring acceptable grounding pseudo-labels. In the explicit stage, to explicitly optimize grounding objectives, we train one fully-supervised model using obtained pseudo-labels for grounding refinement and denoising. Extensive experiments and thoroughly ablations on Charades-STA and ActivityNet Captions demonstrate the significance of partial supervision, as well as our superior performance.

MedS$^3$: Towards Medical Small Language Models with Self-Evolved Slow Thinking

Medical language models (MLMs) have become pivotal in advancing medical natural language processing. However, prior models that rely on pre-training or supervised fine-tuning often exhibit low data efficiency and limited practicality in real-world clinical applications. While OpenAIs O1 highlights test-time scaling in mathematics, attempts to replicate this approach in medicine typically distill responses from GPT-series models to open-source models, focusing primarily on multiple-choice tasks. This strategy, though straightforward, neglects critical concerns like data privacy and realistic deployment in clinical settings. In this work, we present a deployable, small-scale medical language model, \mone, designed for long-chain reasoning in clinical tasks using a self-evolution paradigm. Starting with a seed dataset of around 8,000 instances spanning five domains and 16 datasets, we prompt a base policy model to perform Monte Carlo Tree Search (MCTS) to construct verifiable reasoning chains. Each reasoning step is assigned an evolution rollout value, allowing verified trajectories to train the policy model and the reward model. During inference, the policy model generates multiple responses, and the reward model selects the one with the highest reward score. Experiments on eleven evaluation datasets demonstrate that \mone outperforms prior open-source models by 2 points, with the addition of the reward model further boosting performance ($\sim$13 points), surpassing GPT-4o-mini. Code and data are available at \url{https://github.com/pixas/MedSSS}.

Active Sampling for Node Attribute Completion on Graphs

Node attribute, a type of crucial information for graph analysis, may be partially or completely missing for certain nodes in real world applications. Restoring the missing attributes is expected to benefit downstream graph learning. Few attempts have been made on node attribute completion, but a novel framework called Structure-attribute Transformer (SAT) was recently proposed by using a decoupled scheme to leverage structures and attributes. SAT ignores the differences in contributing to the learning schedule and finding a practical way to model the different importance of nodes with observed attributes is challenging. This paper proposes a novel AcTive Sampling algorithm (ATS) to restore missing node attributes. The representativeness and uncertainty of each node's information are first measured based on graph structure, representation similarity and learning bias. To select nodes as train samples in the next optimization step, a weighting scheme controlled by Beta distribution is then introduced to linearly combine the two properties. Extensive experiments on four public benchmark datasets and two downstream tasks have shown the superiority of ATS in node attribute completion.

A Knowledge-enhanced Pathology Vision-language Foundation Model for Cancer Diagnosis

Deep learning has enabled the development of highly robust foundation models for various pathological tasks across diverse diseases and patient cohorts. Among these models, vision-language pre-training, which leverages large-scale paired data to align pathology image and text embedding spaces, and provides a novel zero-shot paradigm for downstream tasks. However, existing models have been primarily data-driven and lack the incorporation of domain-specific knowledge, which limits their performance in cancer diagnosis, especially for rare tumor subtypes. To address this limitation, we establish a Knowledge-enhanced Pathology (KEEP) foundation model that harnesses disease knowledge to facilitate vision-language pre-training. Specifically, we first construct a disease knowledge graph (KG) that covers 11,454 human diseases with 139,143 disease attributes, including synonyms, definitions, and hypernym relations. We then systematically reorganize the millions of publicly available noisy pathology image-text pairs, into 143K well-structured semantic groups linked through the hierarchical relations of the disease KG. To derive more nuanced image and text representations, we propose a novel knowledge-enhanced vision-language pre-training approach that integrates disease knowledge into the alignment within hierarchical semantic groups instead of unstructured image-text pairs. Validated on 18 diverse benchmarks with more than 14,000 whole slide images (WSIs), KEEP achieves state-of-the-art performance in zero-shot cancer diagnostic tasks. Notably, for cancer detection, KEEP demonstrates an average sensitivity of 89.8% at a specificity of 95.0% across 7 cancer types. For cancer subtyping, KEEP achieves a median balanced accuracy of 0.456 in subtyping 30 rare brain cancers, indicating strong generalizability for diagnosing rare tumors.

Can Modern LLMs Act as Agent Cores in Radiology~Environments?

Advancements in large language models (LLMs) have paved the way for LLM-based agent systems that offer enhanced accuracy and interpretability across various domains. Radiology, with its complex analytical requirements, is an ideal field for the application of these agents. This paper aims to investigate the pre-requisite question for building concrete radiology agents which is, `Can modern LLMs act as agent cores in radiology environments?' To investigate it, we introduce RadABench with three-fold contributions: First, we present RadABench-Data, a comprehensive synthetic evaluation dataset for LLM-based agents, generated from an extensive taxonomy encompassing 6 anatomies, 5 imaging modalities, 10 tool categories, and 11 radiology tasks. Second, we propose RadABench-EvalPlat, a novel evaluation platform for agents featuring a prompt-driven workflow and the capability to simulate a wide range of radiology toolsets. Third, we assess the performance of 7 leading LLMs on our benchmark from 5 perspectives with multiple metrics. Our findings indicate that while current LLMs demonstrate strong capabilities in many areas, they are still not sufficiently advanced to serve as the central agent core in a fully operational radiology agent system. Additionally, we identify key factors influencing the performance of LLM-based agent cores, offering insights for clinicians on how to apply agent systems in real-world radiology practices effectively. All of our code and data are open-sourced in https://github.com/MAGIC-AI4Med/RadABench.

MRGen: Diffusion-based Controllable Data Engine for MRI Segmentation towards Unannotated Modalities

Medical image segmentation has recently demonstrated impressive progress with deep neural networks, yet the heterogeneous modalities and scarcity of mask annotations limit the development of segmentation models on unannotated modalities. This paper investigates a new paradigm for leveraging generative models in medical applications: controllably synthesizing data for unannotated modalities, without requiring registered data pairs. Specifically, we make the following contributions in this paper: (i) we collect and curate a large-scale radiology image-text dataset, MedGen-1M, comprising modality labels, attributes, region, and organ information, along with a subset of organ mask annotations, to support research in controllable medical image generation; (ii) we propose a diffusion-based data engine, termed MRGen, which enables generation conditioned on text prompts and masks, synthesizing MR images for diverse modalities lacking mask annotations, to train segmentation models on unannotated modalities; (iii) we conduct extensive experiments across various modalities, illustrating that our data engine can effectively synthesize training samples and extend MRI segmentation towards unannotated modalities.

Towards Universal Soccer Video Understanding

As a globally celebrated sport, soccer has attracted widespread interest from fans over the world. This paper aims to develop a comprehensive multi-modal framework for soccer video understanding. Specifically, we make the following contributions in this paper: (i) we introduce SoccerReplay-1988, the largest multi-modal soccer dataset to date, featuring videos and detailed annotations from 1,988 complete matches, with an automated annotation pipeline; (ii) we present the first visual-language foundation model in the soccer domain, MatchVision, which leverages spatiotemporal information across soccer videos and excels in various downstream tasks; (iii) we conduct extensive experiments and ablation studies on action classification, commentary generation, and multi-view foul recognition, and demonstrate state-of-the-art performance on all of them, substantially outperforming existing models, which has demonstrated the superiority of our proposed data and model. We believe that this work will offer a standard paradigm for sports understanding research. The code and model will be publicly available for reproduction.

Continual Task Learning through Adaptive Policy Self-Composition

Training a generalizable agent to continually learn a sequence of tasks from offline trajectories is a natural requirement for long-lived agents, yet remains a significant challenge for current offline reinforcement learning (RL) algorithms. Specifically, an agent must be able to rapidly adapt to new tasks using newly collected trajectories (plasticity), while retaining knowledge from previously learned tasks (stability). However, systematic analyses of this setting are scarce, and it remains unclear whether conventional continual learning (CL) methods are effective in continual offline RL (CORL) scenarios. In this study, we develop the Offline Continual World benchmark and demonstrate that traditional CL methods struggle with catastrophic forgetting, primarily due to the unique distribution shifts inherent to CORL scenarios. To address this challenge, we introduce CompoFormer, a structure-based continual transformer model that adaptively composes previous policies via a meta-policy network. Upon encountering a new task, CompoFormer leverages semantic correlations to selectively integrate relevant prior policies alongside newly trained parameters, thereby enhancing knowledge sharing and accelerating the learning process. Our experiments reveal that CompoFormer outperforms conventional CL methods, particularly in longer task sequences, showcasing a promising balance between plasticity and stability.

AuscultaBase: A Foundational Step Towards AI-Powered Body Sound Diagnostics

Auscultation of internal body sounds is essential for diagnosing a range of health conditions, yet its effectiveness is often limited by clinicians' expertise and the acoustic constraints of human hearing, restricting its use across various clinical scenarios. To address these challenges, we introduce AuscultaBase, a foundational framework aimed at advancing body sound diagnostics through innovative data integration and contrastive learning techniques. Our contributions include the following: First, we compile AuscultaBase-Corpus, a large-scale, multi-source body sound database encompassing 11 datasets with 40,317 audio recordings and totaling 322.4 hours of heart, lung, and bowel sounds. Second, we develop AuscultaBase-Model, a foundational diagnostic model for body sounds, utilizing contrastive learning on the compiled corpus. Third, we establish AuscultaBase-Bench, a comprehensive benchmark containing 16 sub-tasks, assessing the performance of various open-source acoustic pre-trained models. Evaluation results indicate that our model outperforms all other open-source models in 12 out of 16 tasks, demonstrating the efficacy of our approach in advancing diagnostic capabilities for body sound analysis.

Prompt Tuning with Diffusion for Few-Shot Pre-trained Policy Generalization

Offline reinforcement learning (RL) methods harness previous experiences to derive an optimal policy, forming the foundation for pre-trained large-scale models (PLMs). When encountering tasks not seen before, PLMs often utilize several expert trajectories as prompts to expedite their adaptation to new requirements. Though a range of prompt-tuning methods have been proposed to enhance the quality of prompts, these methods often face optimization restrictions due to prompt initialization, which can significantly constrain the exploration domain and potentially lead to suboptimal solutions. To eliminate the reliance on the initial prompt, we shift our perspective towards the generative model, framing the prompt-tuning process as a form of conditional generative modeling, where prompts are generated from random noise. Our innovation, the Prompt Diffuser, leverages a conditional diffusion model to produce prompts of exceptional quality. Central to our framework is the approach to trajectory reconstruction and the meticulous integration of downstream task guidance during the training phase. Further experimental results underscore the potency of the Prompt Diffuser as a robust and effective tool for the prompt-tuning process, demonstrating strong performance in the meta-RL tasks.