CureGraph: Contrastive Multi-Modal Graph Representation Learning for Urban Living Circle Health Profiling and Prediction

The early detection and prediction of health status decline among the elderly at the neighborhood level are of great significance for urban planning and public health policymaking. While existing studies affirm the connection between living environments and health outcomes, most rely on single data modalities or simplistic feature concatenation of multi-modal information, limiting their ability to comprehensively profile the health-oriented urban environments. To fill this gap, we propose CureGraph, a contrastive multi-modal representation learning framework for urban health prediction that employs graph-based techniques to infer the prevalence of common chronic diseases among the elderly within the urban living circles of each neighborhood. CureGraph leverages rich multi-modal information, including photos and textual reviews of residential areas and their surrounding points of interest, to generate urban neighborhood embeddings. By integrating pre-trained visual and textual encoders with graph modeling techniques, CureGraph captures cross-modal spatial dependencies, offering a comprehensive understanding of urban environments tailored to elderly health considerations. Extensive experiments on real-world datasets demonstrate that CureGraph improves the best baseline by $28\%$ on average in terms of $R^2$ across elderly disease risk prediction tasks. Moreover, the model enables the identification of stage-wise chronic disease progression and supports comparative public health analysis across neighborhoods, offering actionable insights for sustainable urban development and enhanced quality of life. The code is publicly available at https://github.com/jinlin2021/CureGraph.

Universal Features Guided Zero-Shot Category-Level Object Pose Estimation

Object pose estimation, crucial in computer vision and robotics applications, faces challenges with the diversity of unseen categories. We propose a zero-shot method to achieve category-level 6-DOF object pose estimation, which exploits both 2D and 3D universal features of input RGB-D image to establish semantic similarity-based correspondences and can be extended to unseen categories without additional model fine-tuning. Our method begins with combining efficient 2D universal features to find sparse correspondences between intra-category objects and gets initial coarse pose. To handle the correspondence degradation of 2D universal features if the pose deviates much from the target pose, we use an iterative strategy to optimize the pose. Subsequently, to resolve pose ambiguities due to shape differences between intra-category objects, the coarse pose is refined by optimizing with dense alignment constraint of 3D universal features. Our method outperforms previous methods on the REAL275 and Wild6D benchmarks for unseen categories.

MotifGPL: Motif-Enhanced Graph Prototype Learning for Deciphering Urban Social Segregation

Social segregation in cities, spanning racial, residential, and income dimensions, is becoming more diverse and severe. As urban spaces and social relations grow more complex, residents in metropolitan areas experience varying levels of social segregation. If left unaddressed, this could lead to increased crime rates, heightened social tensions, and other serious issues. Effectively quantifying and analyzing the structures within urban spaces and resident interactions is crucial for addressing segregation. Previous studies have mainly focused on surface-level indicators of urban segregation, lacking comprehensive analyses of urban structure and mobility. This limitation fails to capture the full complexity of segregation. To address this gap, we propose a framework named Motif-Enhanced Graph Prototype Learning (MotifGPL),which consists of three key modules: prototype-based graph structure extraction, motif distribution discovery, and urban graph structure reconstruction. Specifically, we use graph structure prototype learning to extract key prototypes from both the urban spatial graph and the origin-destination graph, incorporating key urban attributes such as points of interest, street view images, and flow indices. To enhance interpretability, the motif distribution discovery module matches each prototype with similar motifs, representing simpler graph structures reflecting local patterns. Finally, we use the motif distribution results to guide the reconstruction of the two graphs. This model enables a detailed exploration of urban spatial structures and resident mobility patterns, helping identify and analyze motif patterns that influence urban segregation, guiding the reconstruction of urban graph structures. Experimental results demonstrate that MotifGPL effectively reveals the key motifs affecting urban social segregation and offer robust guidance for mitigating this issue.

FAP-CD: Fairness-Driven Age-Friendly Community Planning via Conditional Diffusion Generation

As global populations age rapidly, incorporating age-specific considerations into urban planning has become essential to addressing the urgent demand for age-friendly built environments and ensuring sustainable urban development. However, current practices often overlook these considerations, resulting in inadequate and unevenly distributed elderly services in cities. There is a pressing need for equitable and optimized urban renewal strategies to support effective age-friendly planning. To address this challenge, we propose a novel framework, Fairness-driven Age-friendly community Planning via Conditional Diffusion generation (FAP-CD). FAP-CD leverages a conditioned graph denoising diffusion probabilistic model to learn the joint probability distribution of aging facilities and their spatial relationships at a fine-grained regional level. Our framework generates optimized facility distributions by iteratively refining noisy graphs, conditioned on the needs of the elderly during the diffusion process. Key innovations include a demand-fairness pre-training module that integrates community demand features and facility characteristics using an attention mechanism and min-max optimization, ensuring equitable service distribution across regions. Additionally, a discrete graph structure captures walkable accessibility within regional road networks, guiding model sampling. To enhance information integration, we design a graph denoising network with an attribute augmentation module and a hybrid graph message aggregation module, combining local and global node and edge information. Empirical results across multiple metrics demonstrate the effectiveness of FAP-CD in balancing age-friendly needs with regional equity, achieving an average improvement of 41% over competitive baseline models.

A Knowledge-enhanced Pathology Vision-language Foundation Model for Cancer Diagnosis

Deep learning has enabled the development of highly robust foundation models for various pathological tasks across diverse diseases and patient cohorts. Among these models, vision-language pre-training, which leverages large-scale paired data to align pathology image and text embedding spaces, and provides a novel zero-shot paradigm for downstream tasks. However, existing models have been primarily data-driven and lack the incorporation of domain-specific knowledge, which limits their performance in cancer diagnosis, especially for rare tumor subtypes. To address this limitation, we establish a Knowledge-enhanced Pathology (KEEP) foundation model that harnesses disease knowledge to facilitate vision-language pre-training. Specifically, we first construct a disease knowledge graph (KG) that covers 11,454 human diseases with 139,143 disease attributes, including synonyms, definitions, and hypernym relations. We then systematically reorganize the millions of publicly available noisy pathology image-text pairs, into 143K well-structured semantic groups linked through the hierarchical relations of the disease KG. To derive more nuanced image and text representations, we propose a novel knowledge-enhanced vision-language pre-training approach that integrates disease knowledge into the alignment within hierarchical semantic groups instead of unstructured image-text pairs. Validated on 18 diverse benchmarks with more than 14,000 whole slide images (WSIs), KEEP achieves state-of-the-art performance in zero-shot cancer diagnostic tasks. Notably, for cancer detection, KEEP demonstrates an average sensitivity of 89.8% at a specificity of 95.0% across 7 cancer types. For cancer subtyping, KEEP achieves a median balanced accuracy of 0.456 in subtyping 30 rare brain cancers, indicating strong generalizability for diagnosing rare tumors.

POINTS1.5: Building a Vision-Language Model towards Real World Applications

Vision-language models have made significant strides recently, demonstrating superior performance across a range of tasks, e.g. optical character recognition and complex diagram analysis. Building on this trend, we introduce a new vision-language model, POINTS1.5, designed to excel in various real-world applications. POINTS1.5 is an enhancement of POINTS1.0 and incorporates several key innovations: i) We replace the original CLIP vision encoder, which had a fixed image resolution, with a NaViT-style vision encoder that supports native dynamic high resolution. This allows POINTS1.5 to process images of any resolution without needing to split them into tiles. ii) We add bilingual support to POINTS1.5, significantly enhancing its capability in Chinese. Due to the scarcity of open-source Chinese datasets for vision-language models, we collect numerous images from the Internet and annotate them using a combination of manual and automatic methods. iii) We propose a set of rigorous filtering methods for visual instruction tuning datasets. We comprehensively evaluate all these filtering methods, and choose the most effective ones to obtain the final visual instruction tuning set. Thanks to these innovations, POINTS1.5 significantly outperforms POINTS1.0 and demonstrates strong performance across a range of real-world applications. Notably, POINTS1.5-7B is trained on fewer than 4 billion tokens and ranks first on the OpenCompass leaderboard among models with fewer than 10 billion parameters

DEIM: DETR with Improved Matching for Fast Convergence

We introduce DEIM, an innovative and efficient training framework designed to accelerate convergence in real-time object detection with Transformer-based architectures (DETR). To mitigate the sparse supervision inherent in one-to-one (O2O) matching in DETR models, DEIM employs a Dense O2O matching strategy. This approach increases the number of positive samples per image by incorporating additional targets, using standard data augmentation techniques. While Dense O2O matching speeds up convergence, it also introduces numerous low-quality matches that could affect performance. To address this, we propose the Matchability-Aware Loss (MAL), a novel loss function that optimizes matches across various quality levels, enhancing the effectiveness of Dense O2O. Extensive experiments on the COCO dataset validate the efficacy of DEIM. When integrated with RT-DETR and D-FINE, it consistently boosts performance while reducing training time by 50%. Notably, paired with RT-DETRv2, DEIM achieves 53.2% AP in a single day of training on an NVIDIA 4090 GPU. Additionally, DEIM-trained real-time models outperform leading real-time object detectors, with DEIM-D-FINE-L and DEIM-D-FINE-X achieving 54.7% and 56.5% AP at 124 and 78 FPS on an NVIDIA T4 GPU, respectively, without the need for additional data. We believe DEIM sets a new baseline for advancements in real-time object detection. Our code and pre-trained models are available at https://github.com/ShihuaHuang95/DEIM.

AutoMIR: Effective Zero-Shot Medical Information Retrieval without Relevance Labels

Medical information retrieval (MIR) is essential for retrieving relevant medical knowledge from diverse sources, including electronic health records, scientific literature, and medical databases. However, achieving effective zero-shot dense retrieval in the medical domain poses substantial challenges due to the lack of relevance-labeled data. In this paper, we introduce a novel approach called Self-Learning Hypothetical Document Embeddings (SL-HyDE) to tackle this issue. SL-HyDE leverages large language models (LLMs) as generators to generate hypothetical documents based on a given query. These generated documents encapsulate key medical context, guiding a dense retriever in identifying the most relevant documents. The self-learning framework progressively refines both pseudo-document generation and retrieval, utilizing unlabeled medical corpora without requiring any relevance-labeled data. Additionally, we present the Chinese Medical Information Retrieval Benchmark (CMIRB), a comprehensive evaluation framework grounded in real-world medical scenarios, encompassing five tasks and ten datasets. By benchmarking ten models on CMIRB, we establish a rigorous standard for evaluating medical information retrieval systems. Experimental results demonstrate that SL-HyDE significantly surpasses existing methods in retrieval accuracy while showcasing strong generalization and scalability across various LLM and retriever configurations. CMIRB data and evaluation code are publicly available at: https://github.com/CMIRB-benchmark/CMIRB.

POINTS: Improving Your Vision-language Model with Affordable Strategies

In recent years, vision-language models have made significant strides, excelling in tasks like optical character recognition and geometric problem-solving. However, several critical issues remain: 1) Proprietary models often lack transparency about their architectures, while open-source models need more detailed ablations of their training strategies. 2) Pre-training data in open-source works is under-explored, with datasets added empirically, making the process cumbersome. 3) Fine-tuning often focuses on adding datasets, leading to diminishing returns. To address these issues, we propose the following contributions: 1) We trained a robust baseline model using the latest advancements in vision-language models, introducing effective improvements and conducting comprehensive ablation and validation for each technique. 2) Inspired by recent work on large language models, we filtered pre-training data using perplexity, selecting the lowest perplexity data for training. This approach allowed us to train on a curated 1M dataset, achieving competitive performance. 3) During visual instruction tuning, we used model soup on different datasets when adding more datasets yielded marginal improvements. These innovations resulted in a 9B parameter model that performs competitively with state-of-the-art models. Our strategies are efficient and lightweight, making them easily adoptable by the community.

Leveraging Web-Crawled Data for High-Quality Fine-Tuning

Most large language models are fine-tuned using either expensive human-annotated data or GPT-4 generated data which cannot guarantee performance in certain domains. We argue that although the web-crawled data often has formatting errors causing semantic inaccuracies, it can still serve as a valuable source for high-quality supervised fine-tuning in specific domains without relying on advanced models like GPT-4. To this end, we create a paired training dataset automatically by aligning web-crawled data with a smaller set of high-quality data. By training a language model on this dataset, we can convert web data with irregular formats into high-quality ones. Our experiments show that training with the model-transformed data yields better results, surpassing training with only high-quality data by an average score of 9.4% in Chinese math problems. Additionally, our 7B model outperforms several open-source models larger than 32B and surpasses well-known closed-source models such as GPT-3.5, highlighting the efficacy of our approach.