Unsupervised Patch-GAN with Targeted Patch Ranking for Fine-Grained Novelty Detection in Medical Imaging

Detecting novel anomalies in medical imaging is challenging due to the limited availability of labeled data for rare abnormalities, which often display high variability and subtlety. This challenge is further compounded when small abnormal regions are embedded within larger normal areas, as whole-image predictions frequently overlook these subtle deviations. To address these issues, we propose an unsupervised Patch-GAN framework designed to detect and localize anomalies by capturing both local detail and global structure. Our framework first reconstructs masked images to learn fine-grained, normal-specific features, allowing for enhanced sensitivity to minor deviations from normality. By dividing these reconstructed images into patches and assessing the authenticity of each patch, our approach identifies anomalies at a more granular level, overcoming the limitations of whole-image evaluation. Additionally, a patch-ranking mechanism prioritizes regions with higher abnormal scores, reinforcing the alignment between local patch discrepancies and the global image context. Experimental results on the ISIC 2016 skin lesion and BraTS 2019 brain tumor datasets validate our framework's effectiveness, achieving AUCs of 95.79% and 96.05%, respectively, and outperforming three state-of-the-art baselines.

ReferDINO: Referring Video Object Segmentation with Visual Grounding Foundations

Referring video object segmentation (RVOS) aims to segment target objects throughout a video based on a text description. Despite notable progress in recent years, current RVOS models remain struggle to handle complicated object descriptions due to their limited video-language understanding. To address this limitation, we present \textbf{ReferDINO}, an end-to-end RVOS model that inherits strong vision-language understanding from the pretrained visual grounding foundation models, and is further endowed with effective temporal understanding and object segmentation capabilities. In ReferDINO, we contribute three technical innovations for effectively adapting the foundation models to RVOS: 1) an object-consistent temporal enhancer that capitalizes on the pretrained object-text representations to enhance temporal understanding and object consistency; 2) a grounding-guided deformable mask decoder that integrates text and grounding conditions to generate accurate object masks; 3) a confidence-aware query pruning strategy that significantly improves the object decoding efficiency without compromising performance. We conduct extensive experiments on five public RVOS benchmarks to demonstrate that our proposed ReferDINO outperforms state-of-the-art methods significantly. Project page: \url{https://isee-laboratory.github.io/ReferDINO}

Hengqin-RA-v1: Advanced Large Language Model for Diagnosis and Treatment of Rheumatoid Arthritis with Dataset based Traditional Chinese Medicine

Large language models (LLMs) primarily trained on English texts, often face biases and inaccuracies in Chinese contexts. Their limitations are pronounced in fields like Traditional Chinese Medicine (TCM), where cultural and clinical subtleties are vital, further hindered by a lack of domain-specific data, such as rheumatoid arthritis (RA). To address these issues, this paper introduces Hengqin-RA-v1, the first large language model specifically tailored for TCM with a focus on diagnosing and treating RA. We also present HQ-GCM-RA-C1, a comprehensive RA-specific dataset curated from ancient Chinese medical literature, classical texts, and modern clinical studies. This dataset empowers Hengqin-RA-v1 to deliver accurate and culturally informed responses, effectively bridging the gaps left by general-purpose models. Extensive experiments demonstrate that Hengqin-RA-v1 outperforms state-of-the-art models, even surpassing the diagnostic accuracy of TCM practitioners in certain cases.

Bridging the Data Provenance Gap Across Text, Speech and Video

Progress in AI is driven largely by the scale and quality of training data. Despite this, there is a deficit of empirical analysis examining the attributes of well-established datasets beyond text. In this work we conduct the largest and first-of-its-kind longitudinal audit across modalities--popular text, speech, and video datasets--from their detailed sourcing trends and use restrictions to their geographical and linguistic representation. Our manual analysis covers nearly 4000 public datasets between 1990-2024, spanning 608 languages, 798 sources, 659 organizations, and 67 countries. We find that multimodal machine learning applications have overwhelmingly turned to web-crawled, synthetic, and social media platforms, such as YouTube, for their training sets, eclipsing all other sources since 2019. Secondly, tracing the chain of dataset derivations we find that while less than 33% of datasets are restrictively licensed, over 80% of the source content in widely-used text, speech, and video datasets, carry non-commercial restrictions. Finally, counter to the rising number of languages and geographies represented in public AI training datasets, our audit demonstrates measures of relative geographical and multilingual representation have failed to significantly improve their coverage since 2013. We believe the breadth of our audit enables us to empirically examine trends in data sourcing, restrictions, and Western-centricity at an ecosystem-level, and that visibility into these questions are essential to progress in responsible AI. As a contribution to ongoing improvements in dataset transparency and responsible use, we release our entire multimodal audit, allowing practitioners to trace data provenance across text, speech, and video.

TACO: Learning Multi-modal Action Models with Synthetic Chains-of-Thought-and-Action

While open-source multi-modal language models perform well on simple question answering tasks, they often fail on complex questions that require multiple capabilities, such as fine-grained recognition, visual grounding, and reasoning, and that demand multi-step solutions. We present TACO, a family of multi-modal large action models designed to improve performance on such complex, multi-step, and multi-modal tasks. During inference, TACO produces chains-of-thought-and-action (CoTA), executes intermediate steps by invoking external tools such as OCR, depth estimation and calculator, then integrates both the thoughts and action outputs to produce coherent responses. To train TACO, we create a large dataset of over 1M synthetic CoTA traces generated with GPT-4o and Python programs. We then experiment with various data filtering and mixing techniques and obtain a final subset of 293K high-quality CoTA examples. This dataset enables TACO to learn complex reasoning and action paths, surpassing existing models trained on instruction tuning data with only direct answers. Our model TACO outperforms the instruction-tuned baseline across 8 benchmarks, achieving a 3.6% improvement on average, with gains of up to 15% in MMVet tasks involving OCR, mathematical reasoning, and spatial reasoning. Training on high-quality CoTA traces sets a new standard for complex multi-modal reasoning, highlighting the need for structured, multi-step instruction tuning in advancing open-source mutli-modal models' capabilities.

Continual Learning for Segment Anything Model Adaptation

Although the current different types of SAM adaptation methods have achieved promising performance for various downstream tasks, such as prompt-based ones and adapter-based ones, most of them belong to the one-step adaptation paradigm. In real-world scenarios, we are generally confronted with the dynamic scenario where the data comes in a streaming manner. Driven by the practical need, in this paper, we first propose a novel Continual SAM adaptation (CoSAM) benchmark with 8 different task domains and carefully analyze the limitations of the existing SAM one-step adaptation methods in the continual segmentation scenario. Then we propose a novel simple-yet-effective Mixture of Domain Adapters (MoDA) algorithm which utilizes the Global Feature Tokens (GFT) and Global Assistant Tokens (GAT) modules to help the SAM encoder extract well-separated features for different task domains, and then provide the accurate task-specific information for continual learning. Extensive experiments demonstrate that our proposed MoDA obviously surpasses the existing classic continual learning methods, as well as prompt-based and adapter-based approaches for continual segmentation. Moreover, after sequential learning on the CoSAM benchmark with diverse data distributions, our MoDA maintains highly competitive results in the natural image domain, approaching the zero-shot performance of the original SAM, demonstrating its superior capability in knowledge preservation. Notably, the proposed MoDA can be seamlessly integrated into various one-step adaptation methods of SAM, which can consistently bring obvious performance gains. Code is available at \url{https://github.com/yangjl1215/CoSAM}

SpecTool: A Benchmark for Characterizing Errors in Tool-Use LLMs

Evaluating the output of Large Language Models (LLMs) is one of the most critical aspects of building a performant compound AI system. Since the output from LLMs propagate to downstream steps, identifying LLM errors is crucial to system performance. A common task for LLMs in AI systems is tool use. While there are several benchmark environments for evaluating LLMs on this task, they typically only give a success rate without any explanation of the failure cases. To solve this problem, we introduce SpecTool, a new benchmark to identify error patterns in LLM output on tool-use tasks. Our benchmark data set comprises of queries from diverse environments that can be used to test for the presence of seven newly characterized error patterns. Using SPECTOOL , we show that even the most prominent LLMs exhibit these error patterns in their outputs. Researchers can use the analysis and insights from SPECTOOL to guide their error mitigation strategies.

PRACT: Optimizing Principled Reasoning and Acting of LLM Agent

We introduce the Principled Reasoning and Acting (PRAct) framework, a novel method for learning and enforcing action principles from trajectory data. Central to our approach is the use of text gradients from a reflection and optimization engine to derive these action principles. To adapt action principles to specific task requirements, we propose a new optimization framework, Reflective Principle Optimization (RPO). After execution, RPO employs a reflector to critique current action principles and an optimizer to update them accordingly. We develop the RPO framework under two scenarios: Reward-RPO, which uses environmental rewards for reflection, and Self-RPO, which conducts self-reflection without external rewards. Additionally, two RPO methods, RPO-Traj and RPO-Batch, is introduced to adapt to different settings. Experimental results across four environments demonstrate that the PRAct agent, leveraging the RPO framework, effectively learns and applies action principles to enhance performance.

Spatial-Temporal Search for Spiking Neural Networks

Spiking Neural Networks (SNNs) are considered as a potential candidate for the next generation of artificial intelligence with appealing characteristics such as sparse computation and inherent temporal dynamics. By adopting architectures of Artificial Neural Networks (ANNs), SNNs achieve competitive performances on benchmark tasks like image classification. However, successful architectures of ANNs are not optimal for SNNs. In this work, we apply Neural Architecture Search (NAS) to find suitable architectures for SNNs. Previous NAS methods for SNNs focus primarily on the spatial dimension, with a notable lack of consideration for the temporal dynamics that are of critical importance for SNNs. Drawing inspiration from the heterogeneity of biological neural networks, we propose a differentiable approach to optimize SNN on both spatial and temporal dimensions. At spatial level, we have developed a spike-based differentiable hierarchical search (SpikeDHS) framework, where spike-based operation is optimized on both the cell and the layer level under computational constraints. We further propose a differentiable surrogate gradient search (DGS) method to evolve local SG functions independently during training. At temporal level, we explore an optimal configuration of diverse temporal dynamics on different types of spiking neurons by evolving their time constants, based on which we further develop hybrid networks combining SNN and ANN, balancing both accuracy and efficiency. Our methods achieve comparable classification performance of CIFAR10/100 and ImageNet with accuracies of 96.43%, 78.96%, and 70.21%, respectively. On event-based deep stereo, our methods find optimal layer variation and surpass the accuracy of specially designed ANNs with 26$\times$ lower computational cost ($6.7\mathrm{mJ}$), demonstrating the potential of SNN in processing highly sparse and dynamic signals.

An Enhanced Federated Prototype Learning Method under Domain Shift

Federated Learning (FL) allows collaborative machine learning training without sharing private data. Numerous studies have shown that one significant factor affecting the performance of federated learning models is the heterogeneity of data across different clients, especially when the data is sampled from various domains. A recent paper introduces variance-aware dual-level prototype clustering and uses a novel $\alpha$-sparsity prototype loss, which increases intra-class similarity and reduces inter-class similarity. To ensure that the features converge within specific clusters, we introduce an improved algorithm, Federated Prototype Learning with Convergent Clusters, abbreviated as FedPLCC. To increase inter-class distances, we weight each prototype with the size of the cluster it represents. To reduce intra-class distances, considering that prototypes with larger distances might come from different domains, we select only a certain proportion of prototypes for the loss function calculation. Evaluations on the Digit-5, Office-10, and DomainNet datasets show that our method performs better than existing approaches.