Towards prediction of morphological heart age from computed tomography angiography

Age prediction from medical images or other health-related non-imaging data is an important approach to data-driven aging research, providing knowledge of how much information a specific tissue or organ carries about the chronological age of the individual. In this work, we studied the prediction of age from computed tomography angiography (CTA) images, which provide detailed representations of the heart morphology, with the goals of (i) studying the relationship between morphology and aging, and (ii) developing a novel \emph{morphological heart age} biomarker. We applied an image registration-based method that standardizes the images from the whole cohort into a single space. We then extracted supervoxels (using unsupervised segmentation), and corresponding robust features of density and local volume, which provide a detailed representation of the heart morphology while being robust to registration errors. Machine learning models are then trained to fit regression models from these features to the chronological age. We applied the method to a subset of the images from the Swedish CArdioPulomonary bioImage Study (SCAPIS) dataset, consisting of 721 females and 666 males. We observe a mean absolute error of $2.74$ years for females and $2.77$ years for males. The predictions from different sub-regions of interest were observed to be more highly correlated with the predictions from the whole heart, compared to the chronological age, revealing a high consistency in the predictions from morphology. Saliency analysis was also performed on the prediction models to study what regions are associated positively and negatively with the predicted age. This resulted in detailed association maps where the density and volume of known, as well as some novel sub-regions of interest, are determined to be important. The saliency analysis aids in the interpretability of the models and their predictions.

RaSCL: Radar to Satellite Crossview Localization

GNSS is unreliable, inaccurate, and insufficient in many real-time autonomous field applications. In this work, we present a GNSS-free global localization solution that contains a method of registering imaging radar on the ground with overhead RGB imagery, with joint optimization of relative poses from odometry and global poses from our overhead registration. Previous works have used various combinations of ground sensors and overhead imagery, and different feature extraction and matching methods. These include various handcrafted and deep-learning-based methods for extracting features from overhead imagery. Our work presents insights on extracting essential features from RGB overhead images for effective global localization against overhead imagery using only ground radar and a single georeferenced initial guess. We motivate our method by evaluating it on datasets in diverse geographic conditions and robotic platforms, including on an Unmanned Surface Vessel (USV) as well as urban and suburban driving datasets.

Benchmarking the Reproducibility of Brain MRI Segmentation Across Scanners and Time

Accurate and reproducible brain morphometry from structural MRI is critical for monitoring neuroanatomical changes across time and across imaging domains. Although deep learning has accelerated segmentation workflows, scanner-induced variability and reproducibility limitations remain-especially in longitudinal and multi-site settings. In this study, we benchmark two modern segmentation pipelines, FastSurfer and SynthSeg, both integrated into FreeSurfer, one of the most widely adopted tools in neuroimaging. Using two complementary datasets - a 17-year longitudinal cohort (SIMON) and a 9-site test-retest cohort (SRPBS)-we quantify inter-scan segmentation variability using Dice coefficient, Surface Dice, Hausdorff Distance (HD95), and Mean Absolute Percentage Error (MAPE). Our results reveal up to 7-8% volume variation in small subcortical structures such as the amygdala and ventral diencephalon, even under controlled test-retest conditions. This raises a key question: is it feasible to detect subtle longitudinal changes on the order of 5-10% in pea-sized brain regions, given the magnitude of domain-induced morphometric noise? We further analyze the effects of registration templates and interpolation modes, and propose surface-based quality filtering to improve segmentation reliability. This study provides a reproducible benchmark for morphometric reproducibility and emphasizes the need for harmonization strategies in real-world neuroimaging studies. Code and figures: https://github.com/kondratevakate/brain-mri-segmentation

Exploring Generalizable Pre-training for Real-world Change Detection via Geometric Estimation

As an essential procedure in earth observation system, change detection (CD) aims to reveal the spatial-temporal evolution of the observation regions. A key prerequisite for existing change detection algorithms is aligned geo-references between multi-temporal images by fine-grained registration. However, in the majority of real-world scenarios, a prior manual registration is required between the original images, which significantly increases the complexity of the CD workflow. In this paper, we proposed a self-supervision motivated CD framework with geometric estimation, called "MatchCD". Specifically, the proposed MatchCD framework utilizes the zero-shot capability to optimize the encoder with self-supervised contrastive representation, which is reused in the downstream image registration and change detection to simultaneously handle the bi-temporal unalignment and object change issues. Moreover, unlike the conventional change detection requiring segmenting the full-frame image into small patches, our MatchCD framework can directly process the original large-scale image (e.g., 6K*4K resolutions) with promising performance. The performance in multiple complex scenarios with significant geometric distortion demonstrates the effectiveness of our proposed framework.

NTIRE 2025 Challenge on Real-World Face Restoration: Methods and Results

This paper provides a review of the NTIRE 2025 challenge on real-world face restoration, highlighting the proposed solutions and the resulting outcomes. The challenge focuses on generating natural, realistic outputs while maintaining identity consistency. Its goal is to advance state-of-the-art solutions for perceptual quality and realism, without imposing constraints on computational resources or training data. The track of the challenge evaluates performance using a weighted image quality assessment (IQA) score and employs the AdaFace model as an identity checker. The competition attracted 141 registrants, with 13 teams submitting valid models, and ultimately, 10 teams achieved a valid score in the final ranking. This collaborative effort advances the performance of real-world face restoration while offering an in-depth overview of the latest trends in the field.

SC3EF: A Joint Self-Correlation and Cross-Correspondence Estimation Framework for Visible and Thermal Image Registration

Multispectral imaging plays a critical role in a range of intelligent transportation applications, including advanced driver assistance systems (ADAS), traffic monitoring, and night vision. However, accurate visible and thermal (RGB-T) image registration poses a significant challenge due to the considerable modality differences. In this paper, we present a novel joint Self-Correlation and Cross-Correspondence Estimation Framework (SC3EF), leveraging both local representative features and global contextual cues to effectively generate RGB-T correspondences. For this purpose, we design a convolution-transformer-based pipeline to extract local representative features and encode global correlations of intra-modality for inter-modality correspondence estimation between unaligned visible and thermal images. After merging the local and global correspondence estimation results, we further employ a hierarchical optical flow estimation decoder to progressively refine the estimated dense correspondence maps. Extensive experiments demonstrate the effectiveness of our proposed method, outperforming the current state-of-the-art (SOTA) methods on representative RGB-T datasets. Furthermore, it also shows competitive generalization capabilities across challenging scenarios, including large parallax, severe occlusions, adverse weather, and other cross-modal datasets (e.g., RGB-N and RGB-D).

Computer-Aided Design of Personalized Occlusal Positioning Splints Using Multimodal 3D Data

Contemporary digital technology has a pivotal role in the design of customized medical appliances, including occlusal splints used in the treatment of stomatognathic system dysfunctions. We present an approach to computer-aided design and precision assessment of positioning occlusal splints, bridging clinical concepts with current digital dental practice. In our model, a 3D splint is generated based on a transformation matrix that represents the therapeutic change in mandibular position, defined by a specialist using a virtual patient model reconstructed from intraoral scans, CBCT, 3D facial scans and plaster model digitisation. The paper introduces a novel method for generating splints that accurately reproduce occlusal conditions in the therapeutic position, including a mechanism for resolving surface conflicts through virtual embossing. We demonstrate how transformation matrices can be acquired through clinical tools and intraoral devices, and evaluate the accuracy of the designed and printed splints using profile and surface deviation analysis. The proposed method enables reproducible, patient-specific splint fabrication and opens new possibilities in diagnostics, multimodal image registration and quantification of occlusal discrepancies.

Correlation Ratio for Unsupervised Learning of Multi-modal Deformable Registration

In recent years, unsupervised learning for deformable image registration has been a major research focus. This approach involves training a registration network using pairs of moving and fixed images, along with a loss function that combines an image similarity measure and deformation regularization. For multi-modal image registration tasks, the correlation ratio has been a widely-used image similarity measure historically, yet it has been underexplored in current deep learning methods. Here, we propose a differentiable correlation ratio to use as a loss function for learning-based multi-modal deformable image registration. This approach extends the traditionally non-differentiable implementation of the correlation ratio by using the Parzen windowing approximation, enabling backpropagation with deep neural networks. We validated the proposed correlation ratio on a multi-modal neuroimaging dataset. In addition, we established a Bayesian training framework to study how the trade-off between the deformation regularizer and similarity measures, including mutual information and our proposed correlation ratio, affects the registration performance.

A Category-Fragment Segmentation Framework for Pelvic Fracture Segmentation in X-ray Images

Pelvic fractures, often caused by high-impact trauma, frequently require surgical intervention. Imaging techniques such as CT and 2D X-ray imaging are used to transfer the surgical plan to the operating room through image registration, enabling quick intraoperative adjustments. Specifically, segmenting pelvic fractures from 2D X-ray imaging can assist in accurately positioning bone fragments and guiding the placement of screws or metal plates. In this study, we propose a novel deep learning-based category and fragment segmentation (CFS) framework for the automatic segmentation of pelvic bone fragments in 2D X-ray images. The framework consists of three consecutive steps: category segmentation, fragment segmentation, and post-processing. Our best model achieves an IoU of 0.91 for anatomical structures and 0.78 for fracture segmentation. Results demonstrate that the CFS framework is effective and accurate.

Regist3R: Incremental Registration with Stereo Foundation Model

Multi-view 3D reconstruction has remained an essential yet challenging problem in the field of computer vision. While DUSt3R and its successors have achieved breakthroughs in 3D reconstruction from unposed images, these methods exhibit significant limitations when scaling to multi-view scenarios, including high computational cost and cumulative error induced by global alignment. To address these challenges, we propose Regist3R, a novel stereo foundation model tailored for efficient and scalable incremental reconstruction. Regist3R leverages an incremental reconstruction paradigm, enabling large-scale 3D reconstructions from unordered and many-view image collections. We evaluate Regist3R on public datasets for camera pose estimation and 3D reconstruction. Our experiments demonstrate that Regist3R achieves comparable performance with optimization-based methods while significantly improving computational efficiency, and outperforms existing multi-view reconstruction models. Furthermore, to assess its performance in real-world applications, we introduce a challenging oblique aerial dataset which has long spatial spans and hundreds of views. The results highlight the effectiveness of Regist3R. We also demonstrate the first attempt to reconstruct large-scale scenes encompassing over thousands of views through pointmap-based foundation models, showcasing its potential for practical applications in large-scale 3D reconstruction tasks, including urban modeling, aerial mapping, and beyond.