Pattern Recognition Lab, FAU Erlangen-Nürnberg, Germany
Abstract:Accurate multi-organ segmentation in abdominal CT scans is essential for computer-aided diagnosis and treatment. While convolutional neural networks (CNNs) have long been the standard approach in medical image segmentation, transformer-based architectures have recently gained attention due to their ability to model long-range dependencies. In this study, we systematically benchmark the three hybrid transformer-based models UNETR, SwinUNETR, and UNETR++ against a strong CNN baseline, SegResNet, for volumetric multi-organ segmentation on the heterogeneous RATIC dataset. The dataset comprises 206 annotated CT scans from 23 institutions worldwide, covering five abdominal organs. All models were trained and evaluated under identical preprocessing and training conditions using the Dice Similarity Coefficient (DSC) as the primary metric. The results show that the CNN-based SegResNet achieves the highest overall performance, outperforming all hybrid transformer-based models across all organs. Among the transformer-based approaches, UNETR++ delivers the most competitive results, while UNETR demonstrates notably faster convergence with fewer training iterations. These findings suggest that, for small- to medium-sized heterogeneous datasets, well-optimized CNN architectures remain highly competitive and may outperform hybrid transformer-based designs.
Abstract:Precise localization and delineation of brain tumors using Magnetic Resonance Imaging (MRI) are essential for planning therapy and guiding surgical decisions. However, most existing approaches rely on task-specific supervised models and are constrained by the limited availability of annotated data. To address this, we propose LoGSAM, a parameter-efficient, detection-driven framework that transforms radiologist dictation into text prompts for foundation-model-based localization and segmentation. Radiologist speech is first transcribed and translated using a pretrained Whisper ASR model, followed by negation-aware clinical NLP to extract tumor-specific textual prompts. These prompts guide text-conditioned tumor localization via a LoRA-adapted vision-language detection model, Grounding DINO (GDINO). The LoRA adaptation updates using 5% of the model parameters, thereby enabling computationally efficient domain adaptation while preserving pretrained cross-modal knowledge. The predicted bounding boxes are used as prompts for MedSAM to generate pixel-level tumor masks without any additional fine-tuning. Conditioning the frozen MedSAM on LoGSAM-derived priors yields a state-of-the-art dice score of 80.32% on BRISC 2025. In addition, we evaluate the full pipeline using German dictations from a board-certified radiologist on 12 unseen MRI scans, achieving 91.7% case-level accuracy. These results highlight the feasibility of constructing a modular, speech-to-segmentation pipeline by intelligently leveraging pretrained foundation models with minimal parameter updates.
Abstract:Accurate detection and localization of traumatic injuries in abdominal CT scans remains a critical challenge in emergency radiology, primarily due to severe scarcity of annotated medical data. This paper presents a label-efficient approach combining self-supervised pre-training with semi-supervised detection for 3D medical image analysis. We employ patch-based Masked Image Modeling (MIM) to pre-train a 3D U-Net encoder on 1,206 CT volumes without annotations, learning robust anatomical representations. The pretrained encoder enables two downstream clinical tasks: 3D injury detection using VDETR with Vertex Relative Position Encoding, and multi-label injury classification. For detection, semi-supervised learning with 2,000 unlabeled volumes and consistency regularization achieves 56.57% validation mAP@0.50 and 45.30% test mAP@0.50 with only 144 labeled training samples, representing a 115% improvement over supervised-only training. For classification, expanding to 2,244 labeled samples yields 94.07% test accuracy across seven injury categories using only a frozen encoder, demonstrating immediately transferable self-supervised features. Our results validate that self-supervised pre-training combined with semi-supervised learning effectively addresses label scarcity in medical imaging, enabling robust 3D object detection with limited annotations.
Abstract:District Heating Systems are essential infrastructure for delivering heat to consumers across a geographic region sustainably, yet efficient management relies on optimizing diverse energy sources, such as wood, gas, electricity, and solar, in response to fluctuating demand. Aligning supply with demand is critical not only for ensuring reliable heat distribution but also for minimizing carbon emissions and extending infrastructure lifespan through lower operating temperatures. However, accurate multi-step forecasting to support these goals remains challenging due to complex, non-linear usage patterns and external dependencies. In this work, we propose a novel deep learning framework for day-ahead heat demand prediction that leverages time-frequency representations of historical data. By applying Continuous Wavelet Transform to decomposed demand and external meteorological factors, our approach enables Convolutional Neural Networks to learn hierarchical temporal features that are often inaccessible to standard time domain models. We systematically evaluate this method against statistical baselines, state-of-the-art Transformers, and emerging foundation models using multi-year data from three distinct Danish districts, a Danish city, and a German city. The results show a significant advancement, reducing the Mean Absolute Error by 36% to 43% compared to the strongest baselines, achieving forecasting accuracy of up to 95% across annual test datasets. Qualitative and statistical analyses further confirm the accuracy and robustness by reliably tracking volatile demand peaks where others fail. This work contributes both a high-performance forecasting architecture and critical insights into optimal feature composition, offering a validated solution for modern energy applications.
Abstract:State-of-the-art handwritten text recognition (HTR) systems commonly use Transformers, whose growing key-value (KV) cache makes decoding slow and memory-intensive. We introduce DRetHTR, a decoder-only model built on Retentive Networks (RetNet). Compared to an equally sized decoder-only Transformer baseline, DRetHTR delivers 1.6-1.9x faster inference with 38-42% less memory usage, without loss of accuracy. By replacing softmax attention with softmax-free retention and injecting multi-scale sequential priors, DRetHTR avoids a growing KV cache: decoding is linear in output length in both time and memory. To recover the local-to-global inductive bias of attention, we propose layer-wise gamma scaling, which progressively enlarges the effective retention horizon in deeper layers. This encourages early layers to model short-range dependencies and later layers to capture broader context, mitigating the flexibility gap introduced by removing softmax. Consequently, DRetHTR achieves best reported test character error rates of 2.26% (IAM-A, en), 1.81% (RIMES, fr), and 3.46% (Bentham, en), and is competitive on READ-2016 (de) with 4.21%. This demonstrates that decoder-only RetNet enables Transformer-level HTR accuracy with substantially improved decoding speed and memory efficiency.
Abstract:Large language models (LLMs) demonstrate strong general reasoning and language understanding, yet their performance degrades in domains governed by strict formal rules, precise terminology, and legally binding structure. Tax law exemplifies these challenges, as correct answers require exact statutory citation, structured legal argumentation, and numerical accuracy under rigid grading schemes. We algorithmically generate SteuerEx, the first open benchmark derived from authentic German university tax law examinations. SteuerEx comprises 115 expert-validated examination questions spanning six core tax law domains and multiple academic levels, and employs a statement-level, partial-credit evaluation framework that closely mirrors real examination practice. We further present SteuerLLM, a domain-adapted LLM for German tax law trained on a large-scale synthetic dataset generated from authentic examination material using a controlled retrieval-augmented pipeline. SteuerLLM (28B parameters) consistently outperforms general-purpose instruction-tuned models of comparable size and, in several cases, substantially larger systems, demonstrating that domain-specific data and architectural adaptation are more decisive than parameter scale for performance on realistic legal reasoning tasks. All benchmark data, training datasets, model weights, and evaluation code are released openly to support reproducible research in domain-specific legal artificial intelligence. A web-based demo of SteuerLLM is available at https://steuerllm.i5.ai.fau.de.
Abstract:Evaluating lesion evolution in longitudinal CT scans of can cer patients is essential for assessing treatment response, yet establishing reliable lesion correspondence across time remains challenging. Standard bipartite matchers, which rely on geometric proximity, struggle when lesions appear, disappear, merge, or split. We propose a registration-aware matcher based on unbalanced optimal transport (UOT) that accommodates unequal lesion mass and adapts priors to patient-level tumor-load changes. Our transport cost blends (i) size-normalized geometry, (ii) local registration trust from the deformation-field Jacobian, and (iii) optional patch-level appearance consistency. The resulting transport plan is sparsified by relative pruning, yielding one-to-one matches as well as new, disappearing, merging, and splitting lesions without retraining or heuristic rules. On longitudinal CT data, our approach achieves consistently higher edge-detection precision and recall, improved lesion-state recall, and superior lesion-graph component F1 scores versus distance-only baselines.
Abstract:Multi-organ segmentation is a widely applied clinical routine and automated organ segmentation tools dramatically improve the pipeline of the radiologists. Recently, deep learning (DL) based segmentation models have shown the capacity to accomplish such a task. However, the training of the segmentation networks requires large amount of data with manual annotations, which is a major concern due to the data scarcity from clinic. Working with limited data is still common for researches on novel imaging modalities. To enhance the effectiveness of DL models trained with limited data, data augmentation (DA) is a crucial regularization technique. Traditional DA (TDA) strategies focus on basic intra-image operations, i.e. generating images with different orientations and intensity distributions. In contrast, the interimage and object-level DA operations are able to create new images from separate individuals. However, such DA strategies are not well explored on the task of multi-organ segmentation. In this paper, we investigated four possible inter-image DA strategies: CutMix, CarveMix, ObjectAug and AnatoMix, on two organ segmentation datasets. The result shows that CutMix, CarveMix and AnatoMix can improve the average dice score by 4.9, 2.0 and 1.9, compared with the state-of-the-art nnUNet without DA strategies. These results can be further improved by adding TDA strategies. It is revealed in our experiments that Cut-Mix is a robust but simple DA strategy to drive up the segmentation performance for multi-organ segmentation, even when CutMix produces intuitively 'wrong' images. Our implementation is publicly available for future benchmarks.
Abstract:During benchmarking, the state-of-the-art model for glacier calving front delineation achieves near-human performance. However, when applied in a real-world setting at a novel study site, its delineation accuracy is insufficient for calving front products intended for further scientific analyses. This site represents an out-of-distribution domain for a model trained solely on the benchmark dataset. By employing a few-shot domain adaptation strategy, incorporating spatial static prior knowledge, and including summer reference images in the input time series, the delineation error is reduced from 1131.6 m to 68.7 m without any architectural modifications. These methodological advancements establish a framework for applying deep learning-based calving front segmentation to novel study sites, enabling calving front monitoring on a global scale.
Abstract:Art technological investigations of historical panel paintings rely on acquiring multi-modal image data, including visual light photography, infrared reflectography, ultraviolet fluorescence photography, x-radiography, and macro photography. For a comprehensive analysis, the multi-modal images require pixel-wise alignment, which is still often performed manually. Multi-modal image registration can reduce this laborious manual work, is substantially faster, and enables higher precision. Due to varying image resolutions, huge image sizes, non-rigid distortions, and modality-dependent image content, registration is challenging. Therefore, we propose a coarse-to-fine non-rigid multi-modal registration method efficiently relying on sparse keypoints and thin-plate-splines. Historical paintings exhibit a fine crack pattern, called craquelure, on the paint layer, which is captured by all image systems and is well-suited as a feature for registration. In our one-stage non-rigid registration approach, we employ a convolutional neural network for joint keypoint detection and description based on the craquelure and a graph neural network for descriptor matching in a patch-based manner, and filter matches based on homography reprojection errors in local areas. For coarse-to-fine registration, we introduce a novel multi-level keypoint refinement approach to register mixed-resolution images up to the highest resolution. We created a multi-modal dataset of panel paintings with a high number of keypoint annotations, and a large test set comprising five multi-modal domains and varying image resolutions. The ablation study demonstrates the effectiveness of all modules of our refinement method. Our proposed approaches achieve the best registration results compared to competing keypoint and dense matching methods and refinement methods.