Active Evidence-Seeking and Diagnostic Reasoning in Large Language Models for Clinical Decision Support

Large language models perform well on static medical examinations, yet clinical diagnosis often requires iterative evidence gathering under uncertainty. Building on prior interactive evaluation efforts, we introduce an OSCE-inspired standardized patient simulator and a controlled, reproducible benchmark for active diagnostic inquiry. Across 468 cases and 15 models in our protocol, we observe that multi-turn evidence seeking reduces diagnostic accuracy by 12.75% and lowers supporting-evidence quality by 24.36% relative to full-context evaluation; error analyses associate these drops with premature diagnostic closure and inefficient questioning. Together, these results suggest that static full-context benchmarks may overestimate performance in interactive evidence-seeking settings, motivating complementary interactive assessment for safer clinical decision support.

On the Cost and Benefit of Chain of Thought: A Learning-Theoretic Perspective

We develop a learning-theoretic framework for understanding Chain of Thought (CoT). We model CoT as the interaction between an answer map and a chain rule that generates intermediate questions autoregressively, and define the reasoning risk of a hypothesis under this interaction. Our first result is a tight canonical decomposition of this risk into two terms with opposing roles: an oracle-trajectory risk (OTR), which captures the benefit of CoT and reduces to a target-domain risk in a domain adaptation problem, and a trajectory-mismatch risk (TMR), which captures the cost of CoT through error accumulation along mismatched reasoning trajectories. We then show that this cost is unavoidable without structure: if any one of the loss, the hypothesis answer map, or the chain rule lacks stability, the TMR can be arbitrarily large even when the OTR is zero and the hypothesis is uniformly close to the ground truth. Conversely, under stability, we prove a tight upper bound on the TMR governed by an exact amplification factor that identifies bounded, linear, and exponential error-growth regimes. Together, these results give a precise theory of when CoT helps, when it hurts, and what controls the transition between the two.

AiraXiv: An AI-Driven Open-Access Platform for Human and AI Scientists

Recent advances in artificial intelligence (AI) have accelerated the growth of both human-authored and AI-generated research outputs, placing increasing strain on traditional academic publishing systems and challenging the scalability of conference- and journal-centered paradigms amid rising submission volumes, reviewer workload, and venue size. To address these challenges, we explore an AI-era publishing paradigm in which both human and AI scientists participate as authors and readers, and papers evolve through continuous, feedback-driven iteration. We propose AiraXiv, an AI-driven open-access platform built on open preprints, AI-augmented analysis and review, and reader feedback. AiraXiv supports human scientists through an interactive UI and AI scientists through Model Context Protocol (MCP)-based interactions. We validate AiraXiv through real-world deployments, including serving as the submission platform for ICAIS 2025, demonstrating its potential as a fast, inclusive, and scalable research infrastructure for the AI era. AiraXiv is publicly available at https://airaxiv.com.

PhyMotion: Structured 3D Motion Reward for Physics-Grounded Human Video Generation

Generating realistic human motion is a central yet unsolved challenge in video generation. While reinforcement learning (RL)-based post-training has driven recent gains in general video quality, extending it to human motion remains bottlenecked by a reward signal that cannot reliably score motion realism. Existing video rewards primarily rely on 2D perceptual signals, without explicitly modeling the 3D body state, contact, and dynamics underlying articulated human motion, and often assign high scores to videos with floating bodies or physically implausible movements. To address this, we propose PhyMotion, a structured, fine-grained motion reward that grounds recovered 3D human trajectories in a physics simulator and evaluates motion quality along multiple dimensions of physical feasibility. Concretely, we recover SMPL body meshes from generated videos, retarget them onto a humanoid in the MuJoCo physics simulator, and evaluate the resulting motion along three axes: kinematic plausibility, contact and balance consistency, and dynamic feasibility. Each component provides a continuous and interpretable signal tied to a specific aspect of motion quality, allowing the reward to capture which aspects of motion are physically correct or violated. Experiments show that PhyMotion achieves stronger correlation with human judgments than existing reward formulations. These gains carry over to RL-based post-training, where optimizing PhyMotion leads to larger and more consistent improvements than optimizing existing rewards, improving motion realism across both autoregressive and bidirectional video generators under both automatic metrics and blind human evaluation (+68 Elo gain). Ablations show that the three axes provide complementary supervision signals, while the reward preserves overall video generation quality with only modest training overhead.

EgoMemReason: A Memory-Driven Reasoning Benchmark for Long-Horizon Egocentric Video Understanding

Next-generation visual assistants, such as smart glasses, embodied agents, and always-on life-logging systems, must reason over an entire day or more of continuous visual experience. In ultra-long video settings, relevant information is sparsely distributed across hours or days, making memory a fundamental challenge: models must accumulate information over time, recall prior states, track temporal order, and abstract recurring patterns. However, existing week-long video benchmarks are primarily designed for perception and recognition, such as moment localization or global summarization, rather than reasoning that requires integrating evidence across multiple days. To address this gap, we introduce EgoMemReason, a comprehensive benchmark that systematically evaluates week-long egocentric video understanding through memory-driven reasoning. EgoMemReason evaluates three complementary memory types: entity memory, tracking how object states evolve and change across days; event memory, recalling and ordering activities separated by hours or days; and behavior memory, abstracting recurring patterns from sparse, repeated observations over the whole week period. EgoMemReason comprises 500 questions across three memory types and six core challenges, with an average of 5.1 video segments of evidence per question and 25.9 hours of memory backtracking. We evaluate EgoMemReason on 17 methods across MLLMs and agentic frameworks, revealing that even the best model achieves only 39.6% overall accuracy. Further analysis shows that the three memory types fail for distinct reasons and that performance degrades as evidence spans longer temporal horizons, revealing that long-horizon memory remains far from solved. We believe EgoMemReason establishes a strong foundation for evaluating and advancing long-context, memory-aware multimodal systems.

When to Trust Imagination: Adaptive Action Execution for World Action Models

World Action Models (WAMs) have recently emerged as a promising paradigm for robotic manipulation by jointly predicting future visual observations and future actions. However, current WAMs typically execute a fixed number of predicted actions after each model inference, leaving the robot blind to whether the imagined future remains consistent with the actual physical rollout. In this work, we formulate adaptive WAM execution as a future-reality verification problem: the robot should execute longer when the WAM-predicted future remains reliable, and replan earlier when reality deviates from imagination. To this end, we propose Future Forward Dynamics Causal Attention (FFDC), a lightweight verifier that jointly reasons over predicted future actions, predicted visual dynamics, real observations, and language instructions to estimate whether the remaining action rollout can still be trusted. FFDC enables adaptive action chunk sizes as an emergent consequence of prediction-observation consistency, preserving the efficiency of long-horizon execution while restoring responsiveness in contact-rich or difficult phases. We further introduce Mixture-of-Horizon Training to improve long-horizon trajectory coverage for adaptive execution. Experiments on the RoboTwin benchmark and in the real world demonstrate that our method achieves a strong robustness-efficiency trade-off: on RoboTwin, it reduces WAM forward passes by 69.10% and execution time by 34.02%, while improving success rate by 2.54% over the short-chunk baseline; in real-world experiments, it improves success rate by 35%.

FAAST: Forward-Only Associative Learning via Closed-Form Fast Weights for Test-Time Supervised Adaptation

Adapting pretrained models typically involves a trade-off between the high training costs of backpropagation and the heavy inference overhead of memory-based or in-context learning. We propose FAAST, a forward-only associative adaptation method that analytically compiles labeled examples into fast weights in a single pass. By eliminating memory or context dependence, FAAST achieves constant-time inference and decouples task adaptation from pretrained representation. Across image classification and language modeling benchmarks, FAAST matches or exceeds backprop-based adaptation while reducing adaptation time by over 90\% and is competitive to memory/context-based adaptation while saving memory usage by up to 95\%. These results demonstrate FAAST as a highly efficient, scalable solution for supervised task adaptation, particularly for resource-constrained models. We release the code and models at https://github.com/baoguangsheng/faast.

Uni-OPD: Unifying On-Policy Distillation with a Dual-Perspective Recipe

On-policy distillation (OPD) has recently emerged as an effective post-training paradigm for consolidating the capabilities of specialized expert models into a single student model. Despite its empirical success, the conditions under which OPD yields reliable improvement remain poorly understood. In this work, we identify two fundamental bottlenecks that limit effective OPD: insufficient exploration of informative states and unreliable teacher supervision for student rollouts. Building on this insight, we propose Uni-OPD, a unified OPD framework that generalizes across Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs), centered on a dual-perspective optimization strategy. Specifically, from the student's perspective, we adopt two data balancing strategies to promote exploration of informative student-generated states during training. From the teacher's perspective, we show that reliable supervision hinges on whether aggregated token-level guidance remains order-consistent with the outcome reward. To this end, we develop an outcome-guided margin calibration mechanism to restore order consistency between correct and incorrect trajectories. We conduct extensive experiments on 5 domains and 16 benchmarks covering diverse settings, including single-teacher and multi-teacher distillation across LLMs and MLLMs, strong-to-weak distillation, and cross-modal distillation. Our results verify the effectiveness and versatility of Uni-OPD and provide practical insights into reliable OPD.

Triple-Phase Sequential Fusion Network for Hepatobiliary Phase Liver MRI Synthesis

Gadoxetate disodium-enhanced MRI is essential for the detection and characterization of hepatocellular carcinoma. However, acquisition of the hepatobiliary phase (HBP) requires a prolonged post-contrast delay, which reduces workflow efficiency and increases the risk of motion artifacts. In this study, we propose a Triple-Phase Sequential Fusion Network (TriPF-Net) to synthesize HBP images by leveraging the sequential information from pre-HBP sequences: while T1-weighted imaging serves as the indispensable baseline, the model adaptively integrates arterial-phase (AP) and venous-phase (VP) features when available. By modeling the tissue-specific contrast uptake and excretion dynamics across these three phases, TriPF-Net ensures robust HBP synthesis even under the stochastic absence of one or both dynamic contrast-enhanced sequences. The framework comprises an Enhanced Region-Guided Encoder and a Dynamic Feature Unification Module, optimized with a Region-Guided Sequential Fusion Loss to maintain physiological consistency. In addition, clinical variables, including age, sex, total bilirubin, and albumin, are incorporated to enhance physiological consistency. Compared with conventional methods, TriPF-Net achieved superior performance on datasets from two centers. On the internal dataset, the model achieved an MAE of 10.65, a PSNR of 23.27, and an SSIM of 0.76. On the external validation dataset, the corresponding values were 12.41, 23.11, and 0.78, respectively. This flexible solution enhances clinical workflow and lesion depiction, potentially eliminating the need for delayed HBP acquisition in HCC imaging.

3DrawAgent: Teaching LLM to Draw in 3D with Early Contrastive Experience

Sketching in 3D space enables expressive reasoning about shape, structure, and spatial relationships, yet generating 3D sketches through natural language remains a major challenge. In this work, we introduce 3DrawAgent, a training-free, language-driven framework for 3D sketch generation that leverages large language models (LLMs) to sequentially draw 3D Bezier curves under geometric feedback. Unlike prior 2D sketch agents, our method introduces a relative experience optimization strategy that adapts the recently proposed Group Reward Policy Optimization (GRPO) paradigm. Instead of relying on explicit ground-truth supervision, we construct pairwise comparisons among generated sketches, with each pair consisting of a relatively better and a worse result based on CLIP-based perceptual rewards and LLM-based fine-grained qualitative assessment. These experiences are then used to iteratively refine the prior knowledge of 3D drawing, enabling black-box reinforcement of the model's 3D awareness. This design allows our model to self-improve its spatial understanding and drawing quality without parameter updates. Experiments show that 3DrawAgent can generate complex and coherent 3D Bezier sketches from diverse textual prompts, exhibit emergent geometric reasoning, and generalize to novel shapes, establishing a new paradigm for advancing the field of training-free 3D sketch intelligence.