Beyond Words: Augmenting Discriminative Richness via Diffusions in Unsupervised Prompt Learning

Fine-tuning vision-language models (VLMs) with large amounts of unlabeled data has recently garnered significant interest. However, a key challenge remains the lack of high-quality pseudo-labeled data. Current pseudo-labeling strategies often struggle with mismatches between semantic and visual information, leading to sub-optimal performance of unsupervised prompt learning (UPL) methods. In this paper, we introduce a simple yet effective approach called \textbf{A}ugmenting D\textbf{i}scriminative \textbf{R}ichness via Diffusions (AiR), toward learning a richer discriminating way to represent the class comprehensively and thus facilitate classification. Specifically, our approach includes a pseudo-label generation module that leverages high-fidelity synthetic samples to create an auxiliary classifier, which captures richer visual variation, bridging text-image-pair classification to a more robust image-image-pair classification. Additionally, we exploit the diversity of diffusion-based synthetic samples to enhance prompt learning, providing greater information for semantic-visual alignment. Extensive experiments on five public benchmarks, including RESISC45 and Flowers102, and across three learning paradigms-UL, SSL, and TRZSL-demonstrate that AiR achieves substantial and consistent performance improvements over state-of-the-art unsupervised prompt learning methods.

PCM-SAR: Physics-Driven Contrastive Mutual Learning for SAR Classification

Existing SAR image classification methods based on Contrastive Learning often rely on sample generation strategies designed for optical images, failing to capture the distinct semantic and physical characteristics of SAR data. To address this, we propose Physics-Driven Contrastive Mutual Learning for SAR Classification (PCM-SAR), which incorporates domain-specific physical insights to improve sample generation and feature extraction. PCM-SAR utilizes the gray-level co-occurrence matrix (GLCM) to simulate realistic noise patterns and applies semantic detection for unsupervised local sampling, ensuring generated samples accurately reflect SAR imaging properties. Additionally, a multi-level feature fusion mechanism based on mutual learning enables collaborative refinement of feature representations. Notably, PCM-SAR significantly enhances smaller models by refining SAR feature representations, compensating for their limited capacity. Experimental results show that PCM-SAR consistently outperforms SOTA methods across diverse datasets and SAR classification tasks.

Conditional Data Synthesis Augmentation

Reliable machine learning and statistical analysis rely on diverse, well-distributed training data. However, real-world datasets are often limited in size and exhibit underrepresentation across key subpopulations, leading to biased predictions and reduced performance, particularly in supervised tasks such as classification. To address these challenges, we propose Conditional Data Synthesis Augmentation (CoDSA), a novel framework that leverages generative models, such as diffusion models, to synthesize high-fidelity data for improving model performance across multimodal domains including tabular, textual, and image data. CoDSA generates synthetic samples that faithfully capture the conditional distributions of the original data, with a focus on under-sampled or high-interest regions. Through transfer learning, CoDSA fine-tunes pre-trained generative models to enhance the realism of synthetic data and increase sample density in sparse areas. This process preserves inter-modal relationships, mitigates data imbalance, improves domain adaptation, and boosts generalization. We also introduce a theoretical framework that quantifies the statistical accuracy improvements enabled by CoDSA as a function of synthetic sample volume and targeted region allocation, providing formal guarantees of its effectiveness. Extensive experiments demonstrate that CoDSA consistently outperforms non-adaptive augmentation strategies and state-of-the-art baselines in both supervised and unsupervised settings.

Vision Transformers with Autoencoders and Explainable AI for Cancer Patient Risk Stratification Using Whole Slide Imaging

Cancer remains one of the leading causes of mortality worldwide, necessitating accurate diagnosis and prognosis. Whole Slide Imaging (WSI) has become an integral part of clinical workflows with advancements in digital pathology. While various studies have utilized WSIs, their extracted features may not fully capture the most relevant pathological information, and their lack of interpretability limits clinical adoption. In this paper, we propose PATH-X, a framework that integrates Vision Transformers (ViT) and Autoencoders with SHAP (Shapley Additive Explanations) to enhance model explainability for patient stratification and risk prediction using WSIs from The Cancer Genome Atlas (TCGA). A representative image slice is selected from each WSI, and numerical feature embeddings are extracted using Google's pre-trained ViT. These features are then compressed via an autoencoder and used for unsupervised clustering and classification tasks. Kaplan-Meier survival analysis is applied to evaluate stratification into two and three risk groups. SHAP is used to identify key contributing features, which are mapped onto histopathological slices to provide spatial context. PATH-X demonstrates strong performance in breast and glioma cancers, where a sufficient number of WSIs enabled robust stratification. However, performance in lung cancer was limited due to data availability, emphasizing the need for larger datasets to enhance model reliability and clinical applicability.

Comparative Analysis of Unsupervised and Supervised Autoencoders for Nuclei Classification in Clear Cell Renal Cell Carcinoma Images

This study explores the application of supervised and unsupervised autoencoders (AEs) to automate nuclei classification in clear cell renal cell carcinoma (ccRCC) images, a diagnostic task traditionally reliant on subjective visual grading by pathologists. We evaluate various AE architectures, including standard AEs, contractive AEs (CAEs), and discriminative AEs (DAEs), as well as a classifier-based discriminative AE (CDAE), optimized using the hyperparameter tuning tool Optuna. Bhattacharyya distance is selected from several metrics to assess class separability in the latent space, revealing challenges in distinguishing adjacent grades using unsupervised models. CDAE, integrating a supervised classifier branch, demonstrated superior performance in both latent space separation and classification accuracy. Given that CDAE-CNN achieved notable improvements in classification metrics, affirming the value of supervised learning for class-specific feature extraction, F1 score was incorporated into the tuning process to optimize classification performance. Results show significant improvements in identifying aggressive ccRCC grades by leveraging the classification capability of AE through latent clustering followed by fine-grained classification. Our model outperforms the current state of the art, CHR-Network, across all evaluated metrics. These findings suggest that integrating a classifier branch in AEs, combined with neural architecture search and contrastive learning, enhances grading automation in ccRCC pathology, particularly in detecting aggressive tumor grades, and may improve diagnostic accuracy.

It's a (Blind) Match! Towards Vision-Language Correspondence without Parallel Data

The platonic representation hypothesis suggests that vision and language embeddings become more homogeneous as model and dataset sizes increase. In particular, pairwise distances within each modality become more similar. This suggests that as foundation models mature, it may become possible to match vision and language embeddings in a fully unsupervised fashion, i.e. without parallel data. We present the first feasibility study, and investigate conformity of existing vision and language foundation models in the context of unsupervised, or "blind", matching. First, we formulate unsupervised matching as a quadratic assignment problem and introduce a novel heuristic that outperforms previous solvers. We also develop a technique to find optimal matching problems, for which a non-trivial match is very likely. Second, we conduct an extensive study deploying a range of vision and language models on four datasets. Our analysis reveals that for many problem instances, vision and language representations can be indeed matched without supervision. This finding opens up the exciting possibility of embedding semantic knowledge into other modalities virtually annotation-free. As a proof of concept, we showcase an unsupervised classifier, which achieves non-trivial classification accuracy without any image-text annotation.

PolypSegTrack: Unified Foundation Model for Colonoscopy Video Analysis

Early detection, accurate segmentation, classification and tracking of polyps during colonoscopy are critical for preventing colorectal cancer. Many existing deep-learning-based methods for analyzing colonoscopic videos either require task-specific fine-tuning, lack tracking capabilities, or rely on domain-specific pre-training. In this paper, we introduce \textit{PolypSegTrack}, a novel foundation model that jointly addresses polyp detection, segmentation, classification and unsupervised tracking in colonoscopic videos. Our approach leverages a novel conditional mask loss, enabling flexible training across datasets with either pixel-level segmentation masks or bounding box annotations, allowing us to bypass task-specific fine-tuning. Our unsupervised tracking module reliably associates polyp instances across frames using object queries, without relying on any heuristics. We leverage a robust vision foundation model backbone that is pre-trained unsupervisedly on natural images, thereby removing the need for domain-specific pre-training. Extensive experiments on multiple polyp benchmarks demonstrate that our method significantly outperforms existing state-of-the-art approaches in detection, segmentation, classification, and tracking.

Utilization of Neighbor Information for Image Classification with Different Levels of Supervision

We propose to bridge the gap between semi-supervised and unsupervised image recognition with a flexible method that performs well for both generalized category discovery (GCD) and image clustering. Despite the overlap in motivation between these tasks, the methods themselves are restricted to a single task -- GCD methods are reliant on the labeled portion of the data, and deep image clustering methods have no built-in way to leverage the labels efficiently. We connect the two regimes with an innovative approach that Utilizes Neighbor Information for Classification (UNIC) both in the unsupervised (clustering) and semisupervised (GCD) setting. State-of-the-art clustering methods already rely heavily on nearest neighbors. We improve on their results substantially in two parts, first with a sampling and cleaning strategy where we identify accurate positive and negative neighbors, and secondly by finetuning the backbone with clustering losses computed by sampling both types of neighbors. We then adapt this pipeline to GCD by utilizing the labelled images as ground truth neighbors. Our method yields state-of-the-art results for both clustering (+3% ImageNet-100, Imagenet200) and GCD (+0.8% ImageNet-100, +5% CUB, +2% SCars, +4% Aircraft).

Revisiting Automatic Data Curation for Vision Foundation Models in Digital Pathology

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly heterogeneous tiles extracted from whole-slide images (WSIs) of real-world patient samples. The performance of these FMs is significantly influenced by the size, diversity, and balance of the pre-training data. However, data selection has been primarily guided by expert knowledge at the WSI level, focusing on factors such as disease classification and tissue types, while largely overlooking the granular details available at the tile level. In this paper, we investigate the potential of unsupervised automatic data curation at the tile-level, taking into account 350 million tiles. Specifically, we apply hierarchical clustering trees to pre-extracted tile embeddings, allowing us to sample balanced datasets uniformly across the embedding space of the pretrained FM. We further identify these datasets are subject to a trade-off between size and balance, potentially compromising the quality of representations learned by FMs, and propose tailored batch sampling strategies to mitigate this effect. We demonstrate the effectiveness of our method through improved performance on a diverse range of clinically relevant downstream tasks.

A Bird Song Detector for improving bird identification through Deep Learning: a case study from Doñana

Passive Acoustic Monitoring with automatic recorders is essential for ecosystem conservation but generates vast unsupervised audio data, posing challenges for extracting meaningful information. Deep Learning techniques offer a promising solution. BirdNET, a widely used model for bird identification, has shown success in many study systems but is limited in some regions due to biases in its training data. A key challenge in bird species detection is that many recordings either lack target species or contain overlapping vocalizations. To overcome these problems, we developed a multi-stage pipeline for automatic bird vocalization identification in Do\~nana National Park (SW Spain), a region facing significant conservation threats. Our approach included a Bird Song Detector to isolate vocalizations and custom classifiers trained with BirdNET embeddings. We manually annotated 461 minutes of audio from three habitats across nine locations, yielding 3,749 annotations for 34 classes. Spectrograms facilitated the use of image processing techniques. Applying the Bird Song Detector before classification improved species identification, as all classification models performed better when analyzing only the segments where birds were detected. Specifically, the combination of the Bird Song Detector and fine-tuned BirdNET compared to the baseline without the Bird Song Detector. Our approach demonstrated the effectiveness of integrating a Bird Song Detector with fine-tuned classification models for bird identification at local soundscapes. These findings highlight the need to adapt general-purpose tools for specific ecological challenges, as demonstrated in Do\~nana. Automatically detecting bird species serves for tracking the health status of this threatened ecosystem, given the sensitivity of birds to environmental changes, and helps in the design of conservation measures for reducing biodiversity loss