INFANiTE: Implicit Neural representation for high-resolution Fetal brain spatio-temporal Atlas learNing from clinical Thick-slicE MRI

Spatio-temporal fetal brain atlases are important for characterizing normative neurodevelopment and identifying congenital anomalies. However, existing atlas construction pipelines necessitate days for slice-to-volume reconstruction (SVR) to generate high-resolution 3D brain volumes and several additional days for iterative volume registration, thereby rendering atlas construction from large-scale cohorts prohibitively impractical. We address these limitations with INFANiTE, an Implicit Neural Representation (INR) framework for high-resolution Fetal brain spatio-temporal Atlas learNing from clinical Thick-slicE MRI scans, bypassing both the costly SVR and the iterative non-rigid registration steps entirely, thereby substantially accelerating atlas construction. Extensive experiments demonstrate that INFANiTE outperforms existing baselines in subject consistency, reference fidelity, intrinsic quality and biological plausibility, even under challenging sparse-data settings. Additionally, INFANiTE reduces the end-to-end processing time (i.e., from raw scans to the final atlas) from days to hours compared to the traditional 3D volume-based pipeline (e.g., SyGN), facilitating large-scale population-level fetal brain analysis. Our code is publicly available at: https://anonymous.4open.science/r/INFANiTE-5D74

Annotation-free deep learning for detection and segmentation of fetal germinal matrix-intraventricular hemorrhage in brain MRI

Background: Prenatal germinal matrix-intraventricular hemorrhage (GMH-IVH) is a leading cause of infant mortality and neurodevelopmental impairment. Manual diagnosis and lesion segmentation are labor-intensive and error-prone. Deep learning models offer potential for automation but typically require large annotated datasets, which are challenging to obtain. Purpose: To develop and validate an annotation-free deep learning framework for automated detection and segmentation of GMH-IVH on brain MRI. Materials and Methods: This retrospective study analyzed 2D T2-weighted MRI data from pregnant women collected from October 2015 to October 2023 at one hospital (internal validation) and two hospitals (external validation). Eligible participants included healthy fetuses and those with GMH-IVH. FreeHemoSeg was developed and trained using pseudo GMH-IVH images synthesized from normal fetal data guided by medical priors. Primary outcomes included diagnostic accuracy (area under the ROC curve [AUROC], sensitivity, specificity) and segmentation accuracy (Dice similarity coefficient [DSC]). A reader study evaluated clinical utility. Results: A total of 1674 stacks from 558 pregnant women were analyzed. FreeHemoSeg achieved the highest performance in both internal (sensitivity: 0.914, 95% CI 0.869-0.945; specificity: 0.966, 95% CI 0.946-0.978; DSC: 0.559, 95% CI 0.546-0.571) and external validation (sensitivity: 0.824, 95% CI 0.739-0.885; specificity: 0.943, 95% CI 0.913-0.964; DSC: 0.512, 95% CI 0.497-0.526), outperforming supervised and unsupervised methods. FreeHemoSeg assistance improved radiologists' sensitivity (from 0.882 to 0.941-1.000) and diagnostic confidence while reducing interpretation time by 16.0-52.7%. Conclusion: FreeHemoSeg accurately detects and localizes fetal brain hemorrhages without annotated training data, enabling earlier diagnosis and supporting timely clinical management.

Uni-OPD: Unifying On-Policy Distillation with a Dual-Perspective Recipe

On-policy distillation (OPD) has recently emerged as an effective post-training paradigm for consolidating the capabilities of specialized expert models into a single student model. Despite its empirical success, the conditions under which OPD yields reliable improvement remain poorly understood. In this work, we identify two fundamental bottlenecks that limit effective OPD: insufficient exploration of informative states and unreliable teacher supervision for student rollouts. Building on this insight, we propose Uni-OPD, a unified OPD framework that generalizes across Large Language Models (LLMs) and Multimodal Large Language Models (MLLMs), centered on a dual-perspective optimization strategy. Specifically, from the student's perspective, we adopt two data balancing strategies to promote exploration of informative student-generated states during training. From the teacher's perspective, we show that reliable supervision hinges on whether aggregated token-level guidance remains order-consistent with the outcome reward. To this end, we develop an outcome-guided margin calibration mechanism to restore order consistency between correct and incorrect trajectories. We conduct extensive experiments on 5 domains and 16 benchmarks covering diverse settings, including single-teacher and multi-teacher distillation across LLMs and MLLMs, strong-to-weak distillation, and cross-modal distillation. Our results verify the effectiveness and versatility of Uni-OPD and provide practical insights into reliable OPD.

EXACT: an explainable anomaly-aware vision foundation model for analysis of 3D chest CT

Chest computed tomography (CT) is central to the detection and management of thoracic disease, yet the growing scale and complexity of volumetric imaging increasingly exceed what can be addressed by scan-level prediction alone. Clinically useful AI for CT must not only recognize disease across the whole volume, but also localize abnormalities and provide interpretable visual evidence. Existing vision-language foundation models typically compress scans and reports into global image-text representations, limiting their ability to preserve spatial evidence and support clinically meaningful interpretation. Here we developed EXACT, an explainable anomaly-aware foundation model for three-dimensional chest CT that learns spatially resolved representations from paired clinical scans and radiology reports. EXACT was pre-trained on 25,692 CT-reports pairs using anatomy-aware weak supervision, jointly learning organ segmentation and multi-instance anomaly localization without manual voxel-level annotations. The resulting organ-specific anomaly-aware maps assign each voxel a disease-specific anomaly score confined to its corresponding anatomy, jointly encoding lesion extent and organ-level context. In retrospective multinational and multi-center evaluations, EXACT showed broad and consistent improvements across clinically relevant CT tasks, spanning multi-disease diagnosis, zero-shot anomaly localization, downstream adaptation, and visually grounded report generation, outperforming existing three-dimensional medical foundation models. By transforming routine clinical CT scans and free-text reports into explainable voxel-level representations, EXACT establishes a scalable paradigm for trustworthy volumetric medical AI.

The Fourth Challenge on Image Super-Resolution ($\times$4) at NTIRE 2026: Benchmark Results and Method Overview

This paper presents the NTIRE 2026 image super-resolution ($\times$4) challenge, one of the associated competitions of the NTIRE 2026 Workshop at CVPR 2026. The challenge aims to reconstruct high-resolution (HR) images from low-resolution (LR) inputs generated through bicubic downsampling with a $\times$4 scaling factor. The objective is to develop effective super-resolution solutions and analyze recent advances in the field. To reflect the evolving objectives of image super-resolution, the challenge includes two tracks: (1) a restoration track, which emphasizes pixel-wise fidelity and ranks submissions based on PSNR; and (2) a perceptual track, which focuses on visual realism and evaluates results using a perceptual score. A total of 194 participants registered for the challenge, with 31 teams submitting valid entries. This report summarizes the challenge design, datasets, evaluation protocol, main results, and methods of participating teams. The challenge provides a unified benchmark and offers insights into current progress and future directions in image super-resolution.

The Second Challenge on Real-World Face Restoration at NTIRE 2026: Methods and Results

This paper provides a review of the NTIRE 2026 challenge on real-world face restoration, highlighting the proposed solutions and the resulting outcomes. The challenge focuses on generating natural and realistic outputs while maintaining identity consistency. Its goal is to advance state-of-the-art solutions for perceptual quality and realism, without imposing constraints on computational resources or training data. Performance is evaluated using a weighted image quality assessment (IQA) score and employs the AdaFace model as an identity checker. The competition attracted 96 registrants, with 10 teams submitting valid models; ultimately, 9 teams achieved valid scores in the final ranking. This collaborative effort advances the performance of real-world face restoration while offering an in-depth overview of the latest trends in the field.

MIMIC-Py: An Extensible Tool for Personality-Driven Automated Game Testing with Large Language Models

Modern video games are complex, non-deterministic systems that are difficult to test automatically at scale. Although prior work shows that personality-driven Large Language Model (LLM) agents can improve behavioural diversity and test coverage, existing tools largely remain research prototypes and lack cross-game reusability. This tool paper presents MIMIC-Py, a Python-based automated game-testing tool that transforms personality-driven LLM agents into a reusable and extensible framework. MIMIC-Py exposes personality traits as configurable inputs and adopts a modular architecture that decouples planning, execution, and memory from game-specific logic. It supports multiple interaction mechanisms, enabling agents to interact with games via exposed APIs or synthesized code. We describe the design of MIMIC-Py and show how it enables deployment to new game environments with minimal engineering effort, bridging the gap between research prototypes and practical automated game testing. The source code and a demo video are available on our project webpage: https://mimic-persona.github.io/MIMIC-Py-Home-Page/.

VADMamba++: Efficient Video Anomaly Detection via Hybrid Modeling in Grayscale Space

VADMamba pioneered the introduction of Mamba to Video Anomaly Detection (VAD), achieving high accuracy and fast inference through hybrid proxy tasks. Nevertheless, its heavy reliance on optical flow as auxiliary input and inter-task fusion scoring constrains its applicability to a single proxy task. In this paper, we introduce VADMamba++, an efficient VAD method based on the Gray-to-RGB paradigm that enforces a Single-Channel to Three-Channel reconstruction mapping, designed for a single proxy task and operating without auxiliary inputs. This paradigm compels inferring color appearances from grayscale structures, allowing anomalies to be more effectively revealed through dual inconsistencies between structure and chromatic cues. Specifically, VADMamba++ reconstructs grayscale frames into the RGB space to simultaneously discriminate structural geometry and chromatic fidelity, thereby enhancing sensitivity to explicit visual anomalies. We further design a hybrid modeling backbone that integrates Mamba, CNN, and Transformer modules to capture diverse normal patterns while suppressing the appearance of anomalies. Furthermore, an intra-task fusion scoring strategy integrates explicit future-frame prediction errors with implicit quantized feature errors, further improving accuracy under a single task setting. Extensive experiments on three benchmark datasets demonstrate that VADMamba++ outperforms state-of-the-art methods while meeting performance and efficiency, especially under a strict single-task setting with only frame-level inputs.

FetalAgents: A Multi-Agent System for Fetal Ultrasound Image and Video Analysis

Fetal ultrasound (US) is the primary imaging modality for prenatal screening, yet its interpretation relies heavily on the expertise of the clinician. Despite advances in deep learning and foundation models, existing automated tools for fetal US analysis struggle to balance task-specific accuracy with the whole-process versatility required to support end-to-end clinical workflows. To address these limitations, we propose FetalAgents, the first multi-agent system for comprehensive fetal US analysis. Through a lightweight, agentic coordination framework, FetalAgents dynamically orchestrates specialized vision experts to maximize performance across diagnosis, measurement, and segmentation. Furthermore, FetalAgents advances beyond static image analysis by supporting end-to-end video stream summarization, where keyframes are automatically identified across multiple anatomical planes, analyzed by coordinated experts, and synthesized with patient metadata into a structured clinical report. Extensive multi-center external evaluations across eight clinical tasks demonstrate that FetalAgents consistently delivers the most robust and accurate performance when compared against specialized models and multimodal large language models (MLLMs), ultimately providing an auditable, workflow-aligned solution for fetal ultrasound analysis and reporting.

From Verification to Amplification: Auditing Reverse Image Search as Algorithmic Gatekeeping in Visual Misinformation Fact-checking

As visual misinformation becomes increasingly prevalent, platform algorithms act as intermediaries that curate information for users' verification practices. Yet, it remains unclear how algorithmic gatekeeping tools, such as reverse image search (RIS), shape users' information exposure during fact-checking. This study systematically audits Google RIS by reversely searching newly identified misleading images over a 15-day window and analyzing 34,486 collected top-ranked search results. We find that Google RIS returns a substantial volume of irrelevant information and repeated misinformation, whereas debunking content constitutes less than 30% of search results. Debunking content faces visibility challenges in rankings amid repeated misinformation and irrelevant information. Our findings also indicate an inverted U-shaped curve of RIS results page quality over time, likely due to search engine "data voids" when visual falsehoods first appear. These findings contribute to scholarship of visual misinformation verification, and extend algorithmic gatekeeping research to the visual domain.