Robust Divergence Learning for Missing-Modality Segmentation

Multimodal Magnetic Resonance Imaging (MRI) provides essential complementary information for analyzing brain tumor subregions. While methods using four common MRI modalities for automatic segmentation have shown success, they often face challenges with missing modalities due to image quality issues, inconsistent protocols, allergic reactions, or cost factors. Thus, developing a segmentation paradigm that handles missing modalities is clinically valuable. A novel single-modality parallel processing network framework based on H\"older divergence and mutual information is introduced. Each modality is independently input into a shared network backbone for parallel processing, preserving unique information. Additionally, a dynamic sharing framework is introduced that adjusts network parameters based on modality availability. A H\"older divergence and mutual information-based loss functions are used for evaluating discrepancies between predictions and labels. Extensive testing on the BraTS 2018 and BraTS 2020 datasets demonstrates that our method outperforms existing techniques in handling missing modalities and validates each component's effectiveness.

Uncertainty Quantification via Hölder Divergence for Multi-View Representation Learning

Evidence-based deep learning represents a burgeoning paradigm for uncertainty estimation, offering reliable predictions with negligible extra computational overheads. Existing methods usually adopt Kullback-Leibler divergence to estimate the uncertainty of network predictions, ignoring domain gaps among various modalities. To tackle this issue, this paper introduces a novel algorithm based on H\"older Divergence (HD) to enhance the reliability of multi-view learning by addressing inherent uncertainty challenges from incomplete or noisy data. Generally, our method extracts the representations of multiple modalities through parallel network branches, and then employs HD to estimate the prediction uncertainties. Through the Dempster-Shafer theory, integration of uncertainty from different modalities, thereby generating a comprehensive result that considers all available representations. Mathematically, HD proves to better measure the ``distance'' between real data distribution and predictive distribution of the model and improve the performances of multi-class recognition tasks. Specifically, our method surpass the existing state-of-the-art counterparts on all evaluating benchmarks. We further conduct extensive experiments on different backbones to verify our superior robustness. It is demonstrated that our method successfully pushes the corresponding performance boundaries. Finally, we perform experiments on more challenging scenarios, \textit{i.e.}, learning with incomplete or noisy data, revealing that our method exhibits a high tolerance to such corrupted data.

Advanced User Credit Risk Prediction Model using LightGBM, XGBoost and Tabnet with SMOTEENN

Bank credit risk is a significant challenge in modern financial transactions, and the ability to identify qualified credit card holders among a large number of applicants is crucial for the profitability of a bank'sbank's credit card business. In the past, screening applicants'applicants' conditions often required a significant amount of manual labor, which was time-consuming and labor-intensive. Although the accuracy and reliability of previously used ML models have been continuously improving, the pursuit of more reliable and powerful AI intelligent models is undoubtedly the unremitting pursuit by major banks in the financial industry. In this study, we used a dataset of over 40,000 records provided by a commercial bank as the research object. We compared various dimensionality reduction techniques such as PCA and T-SNE for preprocessing high-dimensional datasets and performed in-depth adaptation and tuning of distributed models such as LightGBM and XGBoost, as well as deep models like Tabnet. After a series of research and processing, we obtained excellent research results by combining SMOTEENN with these techniques. The experiments demonstrated that LightGBM combined with PCA and SMOTEENN techniques can assist banks in accurately predicting potential high-quality customers, showing relatively outstanding performance compared to other models.

M4: Multi-Proxy Multi-Gate Mixture of Experts Network for Multiple Instance Learning in Histopathology Image Analysis

Multiple instance learning (MIL) has been successfully applied for whole slide images (WSIs) analysis in computational pathology, enabling a wide range of prediction tasks from tumor subtyping to inferring genetic mutations and multi-omics biomarkers. However, existing MIL methods predominantly focus on single-task learning, resulting in not only overall low efficiency but also the overlook of inter-task relatedness. To address these issues, we proposed an adapted architecture of Multi-gate Mixture-of-experts with Multi-proxy for Multiple instance learning (M4), and applied this framework for simultaneous prediction of multiple genetic mutations from WSIs. The proposed M4 model has two main innovations: (1) utilizing a mixture of experts with multiple gating strategies for multi-genetic mutation prediction on a single pathological slide; (2) constructing multi-proxy expert network and gate network for comprehensive and effective modeling of pathological image information. Our model achieved significant improvements across five tested TCGA datasets in comparison to current state-of-the-art single-task methods. The code is available at:https://github.com/Bigyehahaha/M4.

Self-Adaptive Robust Motion Planning for High DoF Robot Manipulator using Deep MPC

In contemporary control theory, self-adaptive methodologies are highly esteemed for their inherent flexibility and robustness in managing modeling uncertainties. Particularly, robust adaptive control stands out owing to its potent capability of leveraging robust optimization algorithms to approximate cost functions and relax the stringent constraints often associated with conventional self-adaptive control paradigms. Deep learning methods, characterized by their extensive layered architecture, offer significantly enhanced approximation prowess. Notwithstanding, the implementation of deep learning is replete with challenges, particularly the phenomena of vanishing and exploding gradients encountered during the training process. This paper introduces a self-adaptive control scheme integrating a deep MPC, governed by an innovative weight update law designed to mitigate the vanishing and exploding gradient predicament by employing the gradient sign exclusively. The proffered controller is a self-adaptive dynamic inversion mechanism, integrating an augmented state observer within an auxiliary estimation circuit to enhance the training phase. This approach enables the deep MPC to learn the entire plant model in real-time and the efficacy of the controller is demonstrated through simulations involving a high-DoF robot manipulator, wherein the controller adeptly learns the nonlinear plant dynamics expeditiously and exhibits commendable performance in the motion planning task.

Preserving Full Degradation Details for Blind Image Super-Resolution

The performance of image super-resolution relies heavily on the accuracy of degradation information, especially under blind settings. Due to absence of true degradation models in real-world scenarios, previous methods learn distinct representations by distinguishing different degradations in a batch. However, the most significant degradation differences may provide shortcuts for the learning of representations such that subtle difference may be discarded. In this paper, we propose an alternative to learn degradation representations through reproducing degraded low-resolution (LR) images. By guiding the degrader to reconstruct input LR images, full degradation information can be encoded into the representations. In addition, we develop an energy distance loss to facilitate the learning of the degradation representations by introducing a bounded constraint. Experiments show that our representations can extract accurate and highly robust degradation information. Moreover, evaluations on both synthetic and real images demonstrate that our ReDSR achieves state-of-the-art performance for the blind SR tasks.

Dynamic Pseudo Label Optimization in Point-Supervised Nuclei Segmentation

Deep learning has achieved impressive results in nuclei segmentation, but the massive requirement for pixel-wise labels remains a significant challenge. To alleviate the annotation burden, existing methods generate pseudo masks for model training using point labels. However, the generated masks are inevitably different from the ground truth, and these dissimilarities are not handled reasonably during the network training, resulting in the subpar performance of the segmentation model. To tackle this issue, we propose a framework named DoNuSeg, enabling \textbf{D}ynamic pseudo label \textbf{O}ptimization in point-supervised \textbf{Nu}clei \textbf{Seg}mentation. Specifically, DoNuSeg takes advantage of class activation maps (CAMs) to adaptively capture regions with semantics similar to annotated points. To leverage semantic diversity in the hierarchical feature levels, we design a dynamic selection module to choose the optimal one among CAMs from different encoder blocks as pseudo masks. Meanwhile, a CAM-guided contrastive module is proposed to further enhance the accuracy of pseudo masks. In addition to exploiting the semantic information provided by CAMs, we consider location priors inherent to point labels, developing a task-decoupled structure for effectively differentiating nuclei. Extensive experiments demonstrate that DoNuSeg outperforms state-of-the-art point-supervised methods. The code is available at https://github.com/shinning0821/MICCAI24-DoNuSeg.

Applications of Explainable artificial intelligence in Earth system science

In recent years, artificial intelligence (AI) rapidly accelerated its influence and is expected to promote the development of Earth system science (ESS) if properly harnessed. In application of AI to ESS, a significant hurdle lies in the interpretability conundrum, an inherent problem of black-box nature arising from the complexity of AI algorithms. To address this, explainable AI (XAI) offers a set of powerful tools that make the models more transparent. The purpose of this review is twofold: First, to provide ESS scholars, especially newcomers, with a foundational understanding of XAI, serving as a primer to inspire future research advances; second, to encourage ESS professionals to embrace the benefits of AI, free from preconceived biases due to its lack of interpretability. We begin with elucidating the concept of XAI, along with typical methods. We then delve into a review of XAI applications in the ESS literature, highlighting the important role that XAI has played in facilitating communication with AI model decisions, improving model diagnosis, and uncovering scientific insights. We identify four significant challenges that XAI faces within the ESS, and propose solutions. Furthermore, we provide a comprehensive illustration of multifaceted perspectives. Given the unique challenges in ESS, an interpretable hybrid approach that seamlessly integrates AI with domain-specific knowledge appears to be a promising way to enhance the utility of AI in ESS. A visionary outlook for ESS envisions a harmonious blend where process-based models govern the known, AI models explore the unknown, and XAI bridges the gap by providing explanations.

Credit Card Fraud Detection Using Advanced Transformer Model

With the proliferation of various online and mobile payment systems, credit card fraud has emerged as a significant threat to financial security. This study focuses on innovative applications of the latest Transformer models for more robust and precise fraud detection. To ensure the reliability of the data, we meticulously processed the data sources, balancing the dataset to address the issue of data sparsity significantly. We also selected highly correlated vectors to strengthen the training process.To guarantee the reliability and practicality of the new Transformer model, we conducted performance comparisons with several widely adopted models, including Support Vector Machine (SVM), Random Forest, Neural Network, and Logistic Regression. We rigorously compared these models using metrics such as Precision, Recall, and F1 Score. Through these detailed analyses and comparisons, we present to the readers a highly efficient and powerful anti-fraud mechanism with promising prospects. The results demonstrate that the Transformer model not only excels in traditional applications but also shows great potential in niche areas like fraud detection, offering a substantial advancement in the field.

Gaussian Representation for Deformable Image Registration

Deformable image registration (DIR) is a fundamental task in radiotherapy, with existing methods often struggling to balance computational efficiency, registration accuracy, and speed effectively. We introduce a novel DIR approach employing parametric 3D Gaussian control points achieving a better tradeoff. It provides an explicit and flexible representation for spatial deformation fields between 3D volumetric medical images, producing a displacement vector field (DVF) across all volumetric positions. The movement of individual voxels is derived using linear blend skinning (LBS) through localized interpolation of transformations associated with neighboring Gaussians. This interpolation strategy not only simplifies the determination of voxel motions but also acts as an effective regularization technique. Our approach incorporates a unified optimization process through backpropagation, enabling iterative learning of both the parameters of the 3D Gaussians and their transformations. Additionally, the density of Gaussians is adjusted adaptively during the learning phase to accommodate varying degrees of motion complexity. We validated our approach on the 4D-CT lung DIR-Lab and cardiac ACDC datasets, achieving an average target registration error (TRE) of 1.06 mm within a much-improved processing time of 2.43 seconds for the DIR-Lab dataset over existing methods, demonstrating significant advancements in both accuracy and efficiency.