Robust Self-Reconfiguration for Fault-Tolerant Control of Modular Aerial Robot Systems

Modular Aerial Robotic Systems (MARS) consist of multiple drone units assembled into a single, integrated rigid flying platform. With inherent redundancy, MARS can self-reconfigure into different configurations to mitigate rotor or unit failures and maintain stable flight. However, existing works on MARS self-reconfiguration often overlook the practical controllability of intermediate structures formed during the reassembly process, which limits their applicability. In this paper, we address this gap by considering the control-constrained dynamic model of MARS and proposing a robust and efficient self-reconstruction algorithm that maximizes the controllability margin at each intermediate stage. Specifically, we develop algorithms to compute optimal, controllable disassembly and assembly sequences, enabling robust self-reconfiguration. Finally, we validate our method in several challenging fault-tolerant self-reconfiguration scenarios, demonstrating significant improvements in both controllability and trajectory tracking while reducing the number of assembly steps. The videos and source code of this work are available at https://github.com/RuiHuangNUS/MARS-Reconfig/

Robust Fault-Tolerant Control and Agile Trajectory Planning for Modular Aerial Robotic Systems

Modular Aerial Robotic Systems (MARS) consist of multiple drone units that can self-reconfigure to adapt to various mission requirements and fault conditions. However, existing fault-tolerant control methods exhibit significant oscillations during docking and separation, impacting system stability. To address this issue, we propose a novel fault-tolerant control reallocation method that adapts to arbitrary number of modular robots and their assembly formations. The algorithm redistributes the expected collective force and torque required for MARS to individual unit according to their moment arm relative to the center of MARS mass. Furthermore, We propose an agile trajectory planning method for MARS of arbitrary configurations, which is collision-avoiding and dynamically feasible. Our work represents the first comprehensive approach to enable fault-tolerant and collision avoidance flight for MARS. We validate our method through extensive simulations, demonstrating improved fault tolerance, enhanced trajectory tracking accuracy, and greater robustness in cluttered environments. The videos and source code of this work are available at https://github.com/RuiHuangNUS/MARS-FTCC/

DnD Filter: Differentiable State Estimation for Dynamic Systems using Diffusion Models

This paper proposes the DnD Filter, a differentiable filter that utilizes diffusion models for state estimation of dynamic systems. Unlike conventional differentiable filters, which often impose restrictive assumptions on process noise (e.g., Gaussianity), DnD Filter enables a nonlinear state update without such constraints by conditioning a diffusion model on both the predicted state and observational data, capitalizing on its ability to approximate complex distributions. We validate its effectiveness on both a simulated task and a real-world visual odometry task, where DnD Filter consistently outperforms existing baselines. Specifically, it achieves a 25\% improvement in estimation accuracy on the visual odometry task compared to state-of-the-art differentiable filters, and even surpasses differentiable smoothers that utilize future measurements. To the best of our knowledge, DnD Filter represents the first successful attempt to leverage diffusion models for state estimation, offering a flexible and powerful framework for nonlinear estimation under noisy measurements.

Large Language Models for Bioinformatics

With the rapid advancements in large language model (LLM) technology and the emergence of bioinformatics-specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications. This survey aims to address this need by providing a thorough review of BioLMs, focusing on their evolution, classification, and distinguishing features, alongside a detailed examination of training methodologies, datasets, and evaluation frameworks. We explore the wide-ranging applications of BioLMs in critical areas such as disease diagnosis, drug discovery, and vaccine development, highlighting their impact and transformative potential in bioinformatics. We identify key challenges and limitations inherent in BioLMs, including data privacy and security concerns, interpretability issues, biases in training data and model outputs, and domain adaptation complexities. Finally, we highlight emerging trends and future directions, offering valuable insights to guide researchers and clinicians toward advancing BioLMs for increasingly sophisticated biological and clinical applications.

Label-Efficient Data Augmentation with Video Diffusion Models for Guidewire Segmentation in Cardiac Fluoroscopy

The accurate segmentation of guidewires in interventional cardiac fluoroscopy videos is crucial for computer-aided navigation tasks. Although deep learning methods have demonstrated high accuracy and robustness in wire segmentation, they require substantial annotated datasets for generalizability, underscoring the need for extensive labeled data to enhance model performance. To address this challenge, we propose the Segmentation-guided Frame-consistency Video Diffusion Model (SF-VD) to generate large collections of labeled fluoroscopy videos, augmenting the training data for wire segmentation networks. SF-VD leverages videos with limited annotations by independently modeling scene distribution and motion distribution. It first samples the scene distribution by generating 2D fluoroscopy images with wires positioned according to a specified input mask, and then samples the motion distribution by progressively generating subsequent frames, ensuring frame-to-frame coherence through a frame-consistency strategy. A segmentation-guided mechanism further refines the process by adjusting wire contrast, ensuring a diverse range of visibility in the synthesized image. Evaluation on a fluoroscopy dataset confirms the superior quality of the generated videos and shows significant improvements in guidewire segmentation.

Pre-training a Density-Aware Pose Transformer for Robust LiDAR-based 3D Human Pose Estimation

With the rapid development of autonomous driving, LiDAR-based 3D Human Pose Estimation (3D HPE) is becoming a research focus. However, due to the noise and sparsity of LiDAR-captured point clouds, robust human pose estimation remains challenging. Most of the existing methods use temporal information, multi-modal fusion, or SMPL optimization to correct biased results. In this work, we try to obtain sufficient information for 3D HPE only by modeling the intrinsic properties of low-quality point clouds. Hence, a simple yet powerful method is proposed, which provides insights both on modeling and augmentation of point clouds. Specifically, we first propose a concise and effective density-aware pose transformer (DAPT) to get stable keypoint representations. By using a set of joint anchors and a carefully designed exchange module, valid information is extracted from point clouds with different densities. Then 1D heatmaps are utilized to represent the precise locations of the keypoints. Secondly, a comprehensive LiDAR human synthesis and augmentation method is proposed to pre-train the model, enabling it to acquire a better human body prior. We increase the diversity of point clouds by randomly sampling human positions and orientations and by simulating occlusions through the addition of laser-level masks. Extensive experiments have been conducted on multiple datasets, including IMU-annotated LidarHuman26M, SLOPER4D, and manually annotated Waymo Open Dataset v2.0 (Waymo), HumanM3. Our method demonstrates SOTA performance in all scenarios. In particular, compared with LPFormer on Waymo, we reduce the average MPJPE by $10.0mm$. Compared with PRN on SLOPER4D, we notably reduce the average MPJPE by $20.7mm$.

FD2-Net: Frequency-Driven Feature Decomposition Network for Infrared-Visible Object Detection

Infrared-visible object detection (IVOD) seeks to harness the complementary information in infrared and visible images, thereby enhancing the performance of detectors in complex environments. However, existing methods often neglect the frequency characteristics of complementary information, such as the abundant high-frequency details in visible images and the valuable low-frequency thermal information in infrared images, thus constraining detection performance. To solve this problem, we introduce a novel Frequency-Driven Feature Decomposition Network for IVOD, called FD2-Net, which effectively captures the unique frequency representations of complementary information across multimodal visual spaces. Specifically, we propose a feature decomposition encoder, wherein the high-frequency unit (HFU) utilizes discrete cosine transform to capture representative high-frequency features, while the low-frequency unit (LFU) employs dynamic receptive fields to model the multi-scale context of diverse objects. Next, we adopt a parameter-free complementary strengths strategy to enhance multimodal features through seamless inter-frequency recoupling. Furthermore, we innovatively design a multimodal reconstruction mechanism that recovers image details lost during feature extraction, further leveraging the complementary information from infrared and visible images to enhance overall representational capacity. Extensive experiments demonstrate that FD2-Net outperforms state-of-the-art (SOTA) models across various IVOD benchmarks, i.e. LLVIP (96.2% mAP), FLIR (82.9% mAP), and M3FD (83.5% mAP).

Long-Tailed Object Detection Pre-training: Dynamic Rebalancing Contrastive Learning with Dual Reconstruction

Pre-training plays a vital role in various vision tasks, such as object recognition and detection. Commonly used pre-training methods, which typically rely on randomized approaches like uniform or Gaussian distributions to initialize model parameters, often fall short when confronted with long-tailed distributions, especially in detection tasks. This is largely due to extreme data imbalance and the issue of simplicity bias. In this paper, we introduce a novel pre-training framework for object detection, called Dynamic Rebalancing Contrastive Learning with Dual Reconstruction (2DRCL). Our method builds on a Holistic-Local Contrastive Learning mechanism, which aligns pre-training with object detection by capturing both global contextual semantics and detailed local patterns. To tackle the imbalance inherent in long-tailed data, we design a dynamic rebalancing strategy that adjusts the sampling of underrepresented instances throughout the pre-training process, ensuring better representation of tail classes. Moreover, Dual Reconstruction addresses simplicity bias by enforcing a reconstruction task aligned with the self-consistency principle, specifically benefiting underrepresented tail classes. Experiments on COCO and LVIS v1.0 datasets demonstrate the effectiveness of our method, particularly in improving the mAP/AP scores for tail classes.

Evaluation of OpenAI o1: Opportunities and Challenges of AGI

This comprehensive study evaluates the performance of OpenAI's o1-preview large language model across a diverse array of complex reasoning tasks, spanning multiple domains, including computer science, mathematics, natural sciences, medicine, linguistics, and social sciences. Through rigorous testing, o1-preview demonstrated remarkable capabilities, often achieving human-level or superior performance in areas ranging from coding challenges to scientific reasoning and from language processing to creative problem-solving. Key findings include: -83.3% success rate in solving complex competitive programming problems, surpassing many human experts. -Superior ability in generating coherent and accurate radiology reports, outperforming other evaluated models. -100% accuracy in high school-level mathematical reasoning tasks, providing detailed step-by-step solutions. -Advanced natural language inference capabilities across general and specialized domains like medicine. -Impressive performance in chip design tasks, outperforming specialized models in areas such as EDA script generation and bug analysis. -Remarkable proficiency in anthropology and geology, demonstrating deep understanding and reasoning in these specialized fields. -Strong capabilities in quantitative investing. O1 has comprehensive financial knowledge and statistical modeling skills. -Effective performance in social media analysis, including sentiment analysis and emotion recognition. The model excelled particularly in tasks requiring intricate reasoning and knowledge integration across various fields. While some limitations were observed, including occasional errors on simpler problems and challenges with certain highly specialized concepts, the overall results indicate significant progress towards artificial general intelligence.

Auxiliary Input in Training: Incorporating Catheter Features into Deep Learning Models for ECG-Free Dynamic Coronary Roadmapping

Dynamic coronary roadmapping is a technology that overlays the vessel maps (the "roadmap") extracted from an offline image sequence of X-ray angiography onto a live stream of X-ray fluoroscopy in real-time. It aims to offer navigational guidance for interventional surgeries without the need for repeated contrast agent injections, thereby reducing the risks associated with radiation exposure and kidney failure. The precision of the roadmaps is contingent upon the accurate alignment of angiographic and fluoroscopic images based on their cardiac phases, as well as precise catheter tip tracking. The former ensures the selection of a roadmap that closely matches the vessel shape in the current frame, while the latter uses catheter tips as reference points to adjust for translational motion between the roadmap and the present vessel tree. Training deep learning models for both tasks is challenging and underexplored. However, incorporating catheter features into the models could offer substantial benefits, given humans heavily rely on catheters to complete the tasks. To this end, we introduce a simple but effective method, auxiliary input in training (AIT), and demonstrate that it enhances model performance across both tasks, outperforming baseline methods in knowledge incorporation and transfer learning.