Opportunities and Challenges of Large Language Models for Low-Resource Languages in Humanities Research

Low-resource languages serve as invaluable repositories of human history, embodying cultural evolution and intellectual diversity. Despite their significance, these languages face critical challenges, including data scarcity and technological limitations, which hinder their comprehensive study and preservation. Recent advancements in large language models (LLMs) offer transformative opportunities for addressing these challenges, enabling innovative methodologies in linguistic, historical, and cultural research. This study systematically evaluates the applications of LLMs in low-resource language research, encompassing linguistic variation, historical documentation, cultural expressions, and literary analysis. By analyzing technical frameworks, current methodologies, and ethical considerations, this paper identifies key challenges such as data accessibility, model adaptability, and cultural sensitivity. Given the cultural, historical, and linguistic richness inherent in low-resource languages, this work emphasizes interdisciplinary collaboration and the development of customized models as promising avenues for advancing research in this domain. By underscoring the potential of integrating artificial intelligence with the humanities to preserve and study humanity's linguistic and cultural heritage, this study fosters global efforts towards safeguarding intellectual diversity.

QueEn: A Large Language Model for Quechua-English Translation

Recent studies show that large language models (LLMs) are powerful tools for working with natural language, bringing advances in many areas of computational linguistics. However, these models face challenges when applied to low-resource languages due to limited training data and difficulty in understanding cultural nuances. In this paper, we propose QueEn, a novel approach for Quechua-English translation that combines Retrieval-Augmented Generation (RAG) with parameter-efficient fine-tuning techniques. Our method leverages external linguistic resources through RAG and uses Low-Rank Adaptation (LoRA) for efficient model adaptation. Experimental results show that our approach substantially exceeds baseline models, with a BLEU score of 17.6 compared to 1.5 for standard GPT models. The integration of RAG with fine-tuning allows our system to address the challenges of low-resource language translation while maintaining computational efficiency. This work contributes to the broader goal of preserving endangered languages through advanced language technologies.

OracleSage: Towards Unified Visual-Linguistic Understanding of Oracle Bone Scripts through Cross-Modal Knowledge Fusion

Oracle bone script (OBS), as China's earliest mature writing system, present significant challenges in automatic recognition due to their complex pictographic structures and divergence from modern Chinese characters. We introduce OracleSage, a novel cross-modal framework that integrates hierarchical visual understanding with graph-based semantic reasoning. Specifically, we propose (1) a Hierarchical Visual-Semantic Understanding module that enables multi-granularity feature extraction through progressive fine-tuning of LLaVA's visual backbone, (2) a Graph-based Semantic Reasoning Framework that captures relationships between visual components and semantic concepts through dynamic message passing, and (3) OracleSem, a semantically enriched OBS dataset with comprehensive pictographic and semantic annotations. Experimental results demonstrate that OracleSage significantly outperforms state-of-the-art vision-language models. This research establishes a new paradigm for ancient text interpretation while providing valuable technical support for archaeological studies.

Transcending Language Boundaries: Harnessing LLMs for Low-Resource Language Translation

Large Language Models (LLMs) have demonstrated remarkable success across a wide range of tasks and domains. However, their performance in low-resource language translation, particularly when translating into these languages, remains underexplored. This gap poses significant challenges, as linguistic barriers hinder the cultural preservation and development of minority communities. To address this issue, this paper introduces a novel retrieval-based method that enhances translation quality for low-resource languages by focusing on key terms, which involves translating keywords and retrieving corresponding examples from existing data. To evaluate the effectiveness of this method, we conducted experiments translating from English into three low-resource languages: Cherokee, a critically endangered indigenous language of North America; Tibetan, a historically and culturally significant language in Asia; and Manchu, a language with few remaining speakers. Our comparison with the zero-shot performance of GPT-4o and LLaMA 3.1 405B, highlights the significant challenges these models face when translating into low-resource languages. In contrast, our retrieval-based method shows promise in improving both word-level accuracy and overall semantic understanding by leveraging existing resources more effectively.

Towards Next-Generation Medical Agent: How o1 is Reshaping Decision-Making in Medical Scenarios

Artificial Intelligence (AI) has become essential in modern healthcare, with large language models (LLMs) offering promising advances in clinical decision-making. Traditional model-based approaches, including those leveraging in-context demonstrations and those with specialized medical fine-tuning, have demonstrated strong performance in medical language processing but struggle with real-time adaptability, multi-step reasoning, and handling complex medical tasks. Agent-based AI systems address these limitations by incorporating reasoning traces, tool selection based on context, knowledge retrieval, and both short- and long-term memory. These additional features enable the medical AI agent to handle complex medical scenarios where decision-making should be built on real-time interaction with the environment. Therefore, unlike conventional model-based approaches that treat medical queries as isolated questions, medical AI agents approach them as complex tasks and behave more like human doctors. In this paper, we study the choice of the backbone LLM for medical AI agents, which is the foundation for the agent's overall reasoning and action generation. In particular, we consider the emergent o1 model and examine its impact on agents' reasoning, tool-use adaptability, and real-time information retrieval across diverse clinical scenarios, including high-stakes settings such as intensive care units (ICUs). Our findings demonstrate o1's ability to enhance diagnostic accuracy and consistency, paving the way for smarter, more responsive AI tools that support better patient outcomes and decision-making efficacy in clinical practice.

EchoFM: Foundation Model for Generalizable Echocardiogram Analysis

Foundation models have recently gained significant attention because of their generalizability and adaptability across multiple tasks and data distributions. Although medical foundation models have emerged, solutions for cardiac imaging, especially echocardiography videos, are still unexplored. In this paper, we introduce EchoFM, a foundation model specifically designed to represent and analyze echocardiography videos. In EchoFM, we propose a self-supervised learning framework that captures both spatial and temporal variability patterns through a spatio-temporal consistent masking strategy and periodic-driven contrastive learning. This framework can effectively capture the spatio-temporal dynamics of echocardiography and learn the representative video features without any labels. We pre-train our model on an extensive dataset comprising over 290,000 echocardiography videos covering 26 scan views across different imaging modes, with up to 20 million frames of images. The pre-trained EchoFM can then be easily adapted and fine-tuned for a variety of downstream tasks, serving as a robust backbone model. Our evaluation was systemically designed for four downstream tasks after the echocardiography examination routine. Experiment results show that EchoFM surpasses state-of-the-art methods, including specialized echocardiography methods, self-supervised pre-training models, and general-purposed pre-trained foundation models, across all downstream tasks.

Large Language Models for Manufacturing

The rapid advances in Large Language Models (LLMs) have the potential to transform manufacturing industry, offering new opportunities to optimize processes, improve efficiency, and drive innovation. This paper provides a comprehensive exploration of the integration of LLMs into the manufacturing domain, focusing on their potential to automate and enhance various aspects of manufacturing, from product design and development to quality control, supply chain optimization, and talent management. Through extensive evaluations across multiple manufacturing tasks, we demonstrate the remarkable capabilities of state-of-the-art LLMs, such as GPT-4V, in understanding and executing complex instructions, extracting valuable insights from vast amounts of data, and facilitating knowledge sharing. We also delve into the transformative potential of LLMs in reshaping manufacturing education, automating coding processes, enhancing robot control systems, and enabling the creation of immersive, data-rich virtual environments through the industrial metaverse. By highlighting the practical applications and emerging use cases of LLMs in manufacturing, this paper aims to provide a valuable resource for professionals, researchers, and decision-makers seeking to harness the power of these technologies to address real-world challenges, drive operational excellence, and unlock sustainable growth in an increasingly competitive landscape.

EG-SpikeFormer: Eye-Gaze Guided Transformer on Spiking Neural Networks for Medical Image Analysis

Neuromorphic computing has emerged as a promising energy-efficient alternative to traditional artificial intelligence, predominantly utilizing spiking neural networks (SNNs) implemented on neuromorphic hardware. Significant advancements have been made in SNN-based convolutional neural networks (CNNs) and Transformer architectures. However, their applications in the medical imaging domain remain underexplored. In this study, we introduce EG-SpikeFormer, an SNN architecture designed for clinical tasks that integrates eye-gaze data to guide the model's focus on diagnostically relevant regions in medical images. This approach effectively addresses shortcut learning issues commonly observed in conventional models, especially in scenarios with limited clinical data and high demands for model reliability, generalizability, and transparency. Our EG-SpikeFormer not only demonstrates superior energy efficiency and performance in medical image classification tasks but also enhances clinical relevance. By incorporating eye-gaze data, the model improves interpretability and generalization, opening new directions for the application of neuromorphic computing in healthcare.

ECHOPulse: ECG controlled echocardio-grams video generation

Echocardiography (ECHO) is essential for cardiac assessments, but its video quality and interpretation heavily relies on manual expertise, leading to inconsistent results from clinical and portable devices. ECHO video generation offers a solution by improving automated monitoring through synthetic data and generating high-quality videos from routine health data. However, existing models often face high computational costs, slow inference, and rely on complex conditional prompts that require experts' annotations. To address these challenges, we propose ECHOPULSE, an ECG-conditioned ECHO video generation model. ECHOPULSE introduces two key advancements: (1) it accelerates ECHO video generation by leveraging VQ-VAE tokenization and masked visual token modeling for fast decoding, and (2) it conditions on readily accessible ECG signals, which are highly coherent with ECHO videos, bypassing complex conditional prompts. To the best of our knowledge, this is the first work to use time-series prompts like ECG signals for ECHO video generation. ECHOPULSE not only enables controllable synthetic ECHO data generation but also provides updated cardiac function information for disease monitoring and prediction beyond ECG alone. Evaluations on three public and private datasets demonstrate state-of-the-art performance in ECHO video generation across both qualitative and quantitative measures. Additionally, ECHOPULSE can be easily generalized to other modality generation tasks, such as cardiac MRI, fMRI, and 3D CT generation. Demo can seen from \url{https://github.com/levyisthebest/ECHOPulse_Prelease}.

Instruction Embedding: Latent Representations of Instructions Towards Task Identification

Instruction data is crucial for improving the capability of Large Language Models (LLMs) to align with human-level performance. Recent research LIMA demonstrates that alignment is essentially a process where the model adapts instructions' interaction style or format to solve various tasks, leveraging pre-trained knowledge and skills. Therefore, for instructional data, the most important aspect is the task it represents, rather than the specific semantics and knowledge information. The latent representations of instructions play roles for some instruction-related tasks like data selection and demonstrations retrieval. However, they are always derived from text embeddings, encompass overall semantic information that influences the representation of task categories. In this work, we introduce a new concept, instruction embedding, and construct Instruction Embedding Benchmark (IEB) for its training and evaluation. Then, we propose a baseline Prompt-based Instruction Embedding (PIE) method to make the representations more attention on tasks. The evaluation of PIE, alongside other embedding methods on IEB with two designed tasks, demonstrates its superior performance in accurately identifying task categories. Moreover, the application of instruction embeddings in four downstream tasks showcases its effectiveness and suitability for instruction-related tasks.