Prompt to Restore, Restore to Prompt: Cyclic Prompting for Universal Adverse Weather Removal

Universal adverse weather removal (UAWR) seeks to address various weather degradations within a unified framework. Recent methods are inspired by prompt learning using pre-trained vision-language models (e.g., CLIP), leveraging degradation-aware prompts to facilitate weather-free image restoration, yielding significant improvements. In this work, we propose CyclicPrompt, an innovative cyclic prompt approach designed to enhance the effectiveness, adaptability, and generalizability of UAWR. CyclicPrompt Comprises two key components: 1) a composite context prompt that integrates weather-related information and context-aware representations into the network to guide restoration. This prompt differs from previous methods by marrying learnable input-conditional vectors with weather-specific knowledge, thereby improving adaptability across various degradations. 2) The erase-and-paste mechanism, after the initial guided restoration, substitutes weather-specific knowledge with constrained restoration priors, inducing high-quality weather-free concepts into the composite prompt to further fine-tune the restoration process. Therefore, we can form a cyclic "Prompt-Restore-Prompt" pipeline that adeptly harnesses weather-specific knowledge, textual contexts, and reliable textures. Extensive experiments on synthetic and real-world datasets validate the superior performance of CyclicPrompt. The code is available at: https://github.com/RongxinL/CyclicPrompt.

DeepNuParc: A Novel Deep Clustering Framework for Fine-scale Parcellation of Brain Nuclei Using Diffusion MRI Tractography

Brain nuclei are clusters of anatomically distinct neurons that serve as important hubs for processing and relaying information in various neural circuits. Fine-scale parcellation of the brain nuclei is vital for a comprehensive understanding of its anatomico-functional correlations. Diffusion MRI tractography is an advanced imaging technique that can estimate the brain's white matter structural connectivity to potentially reveal the topography of the nuclei of interest for studying its subdivisions. In this work, we present a deep clustering pipeline, namely DeepNuParc, to perform automated, fine-scale parcellation of brain nuclei using diffusion MRI tractography. First, we incorporate a newly proposed deep learning approach to enable accurate segmentation of the nuclei of interest directly on the dMRI data. Next, we design a novel streamline clustering-based structural connectivity feature for a robust representation of voxels within the nuclei. Finally, we improve the popular joint dimensionality reduction and k-means clustering approach to enable nuclei parcellation at a finer scale. We demonstrate DeepNuParc on two important brain structures, i.e. the amygdala and the thalamus, that are known to have multiple anatomically and functionally distinct nuclei subdivisions. Experimental results show that DeepNuParc enables consistent parcellation of the nuclei into multiple parcels across multiple subjects and achieves good correspondence with the widely used coarse-scale atlases. Our codes are available at https://github.com/HarlandZZC/deep_nuclei_parcellation.

TimeFound: A Foundation Model for Time Series Forecasting

We present TimeFound, an encoder-decoder transformer-based time series foundation model for out-of-the-box zero-shot forecasting. To handle time series data from various domains, TimeFound employs a multi-resolution patching strategy to capture complex temporal patterns at multiple scales. We pre-train our model with two sizes (200M and 710M parameters) on a large time-series corpus comprising both real-world and synthetic datasets. Over a collection of unseen datasets across diverse domains and forecasting horizons, our empirical evaluations suggest that TimeFound can achieve superior or competitive zero-shot forecasting performance, compared to state-of-the-art time series foundation models.

DiffKAN-Inpainting: KAN-based Diffusion model for brain tumor inpainting

Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.

Strategic priorities for transformative progress in advancing biology with proteomics and artificial intelligence

Artificial intelligence (AI) is transforming scientific research, including proteomics. Advances in mass spectrometry (MS)-based proteomics data quality, diversity, and scale, combined with groundbreaking AI techniques, are unlocking new challenges and opportunities in biological discovery. Here, we highlight key areas where AI is driving innovation, from data analysis to new biological insights. These include developing an AI-friendly ecosystem for proteomics data generation, sharing, and analysis; improving peptide and protein identification and quantification; characterizing protein-protein interactions and protein complexes; advancing spatial and perturbation proteomics; integrating multi-omics data; and ultimately enabling AI-empowered virtual cells.

Offload Rethinking by Cloud Assistance for Efficient Environmental Sound Recognition on LPWANs

Learning-based environmental sound recognition has emerged as a crucial method for ultra-low-power environmental monitoring in biological research and city-scale sensing systems. These systems usually operate under limited resources and are often powered by harvested energy in remote areas. Recent efforts in on-device sound recognition suffer from low accuracy due to resource constraints, whereas cloud offloading strategies are hindered by high communication costs. In this work, we introduce ORCA, a novel resource-efficient cloud-assisted environmental sound recognition system on batteryless devices operating over the Low-Power Wide-Area Networks (LPWANs), targeting wide-area audio sensing applications. We propose a cloud assistance strategy that remedies the low accuracy of on-device inference while minimizing the communication costs for cloud offloading. By leveraging a self-attention-based cloud sub-spectral feature selection method to facilitate efficient on-device inference, ORCA resolves three key challenges for resource-constrained cloud offloading over LPWANs: 1) high communication costs and low data rates, 2) dynamic wireless channel conditions, and 3) unreliable offloading. We implement ORCA on an energy-harvesting batteryless microcontroller and evaluate it in a real world urban sound testbed. Our results show that ORCA outperforms state-of-the-art methods by up to $80 \times$ in energy savings and $220 \times$ in latency reduction while maintaining comparable accuracy.

KPIs 2024 Challenge: Advancing Glomerular Segmentation from Patch- to Slide-Level

Chronic kidney disease (CKD) is a major global health issue, affecting over 10% of the population and causing significant mortality. While kidney biopsy remains the gold standard for CKD diagnosis and treatment, the lack of comprehensive benchmarks for kidney pathology segmentation hinders progress in the field. To address this, we organized the Kidney Pathology Image Segmentation (KPIs) Challenge, introducing a dataset that incorporates preclinical rodent models of CKD with over 10,000 annotated glomeruli from 60+ Periodic Acid Schiff (PAS)-stained whole slide images. The challenge includes two tasks, patch-level segmentation and whole slide image segmentation and detection, evaluated using the Dice Similarity Coefficient (DSC) and F1-score. By encouraging innovative segmentation methods that adapt to diverse CKD models and tissue conditions, the KPIs Challenge aims to advance kidney pathology analysis, establish new benchmarks, and enable precise, large-scale quantification for disease research and diagnosis.

From Dense to Sparse: Event Response for Enhanced Residential Load Forecasting

Residential load forecasting (RLF) is crucial for resource scheduling in power systems. Most existing methods utilize all given load records (dense data) to indiscriminately extract the dependencies between historical and future time series. However, there exist important regular patterns residing in the event-related associations among different appliances (sparse knowledge), which have yet been ignored. In this paper, we propose an Event-Response Knowledge Guided approach (ERKG) for RLF by incorporating the estimation of electricity usage events for different appliances, mining event-related sparse knowledge from the load series. With ERKG, the event-response estimation enables portraying the electricity consumption behaviors of residents, revealing regular variations in appliance operational states. To be specific, ERKG consists of knowledge extraction and guidance: i) a forecasting model is designed for the electricity usage events by estimating appliance operational states, aiming to extract the event-related sparse knowledge; ii) a novel knowledge-guided mechanism is established by fusing such state estimates of the appliance events into the RLF model, which can give particular focuses on the patterns of users' electricity consumption behaviors. Notably, ERKG can flexibly serve as a plug-in module to boost the capability of existing forecasting models by leveraging event response. In numerical experiments, extensive comparisons and ablation studies have verified the effectiveness of our ERKG, e.g., over 8% MAE can be reduced on the tested state-of-the-art forecasting models.

CHAT: Beyond Contrastive Graph Transformer for Link Prediction in Heterogeneous Networks

Link prediction in heterogeneous networks is crucial for understanding the intricacies of network structures and forecasting their future developments. Traditional methodologies often face significant obstacles, including over-smoothing-wherein the excessive aggregation of node features leads to the loss of critical structural details-and a dependency on human-defined meta-paths, which necessitate extensive domain knowledge and can be inherently restrictive. These limitations hinder the effective prediction and analysis of complex heterogeneous networks. In response to these challenges, we propose the Contrastive Heterogeneous grAph Transformer (CHAT). CHAT introduces a novel sampling-based graph transformer technique that selectively retains nodes of interest, thereby obviating the need for predefined meta-paths. The method employs an innovative connection-aware transformer to encode node sequences and their interconnections with high fidelity, guided by a dual-faceted loss function specifically designed for heterogeneous network link prediction. Additionally, CHAT incorporates an ensemble link predictor that synthesizes multiple samplings to achieve enhanced prediction accuracy. We conducted comprehensive evaluations of CHAT using three distinct drug-target interaction (DTI) datasets. The empirical results underscore CHAT's superior performance, outperforming both general-task approaches and models specialized in DTI prediction. These findings substantiate the efficacy of CHAT in addressing the complex problem of link prediction in heterogeneous networks.

Improving Acoustic Scene Classification in Low-Resource Conditions

Acoustic Scene Classification (ASC) identifies an environment based on an audio signal. This paper explores ASC in low-resource conditions and proposes a novel model, DS-FlexiNet, which combines depthwise separable convolutions from MobileNetV2 with ResNet-inspired residual connections for a balance of efficiency and accuracy. To address hardware limitations and device heterogeneity, DS-FlexiNet employs Quantization Aware Training (QAT) for model compression and data augmentation methods like Auto Device Impulse Response (ADIR) and Freq-MixStyle (FMS) to improve cross-device generalization. Knowledge Distillation (KD) from twelve teacher models further enhances performance on unseen devices. The architecture includes a custom Residual Normalization layer to handle domain differences across devices, and depthwise separable convolutions reduce computational overhead without sacrificing feature representation. Experimental results show that DS-FlexiNet excels in both adaptability and performance under resource-constrained conditions.