ARCHI-TTS: A flow-matching-based Text-to-Speech Model with Self-supervised Semantic Aligner and Accelerated Inference

Although diffusion-based, non-autoregressive text-to-speech (TTS) systems have demonstrated impressive zero-shot synthesis capabilities, their efficacy is still hindered by two key challenges: the difficulty of text-speech alignment modeling and the high computational overhead of the iterative denoising process. To address these limitations, we propose ARCHI-TTS that features a dedicated semantic aligner to ensure robust temporal and semantic consistency between text and audio. To overcome high computational inference costs, ARCHI-TTS employs an efficient inference strategy that reuses encoder features across denoising steps, drastically accelerating synthesis without performance degradation. An auxiliary CTC loss applied to the condition encoder further enhances the semantic understanding. Experimental results demonstrate that ARCHI-TTS achieves a WER of 1.98% on LibriSpeech-PC test-clean, and 1.47%/1.42% on SeedTTS test-en/test-zh with a high inference efficiency, consistently outperforming recent state-of-the-art TTS systems.

SemanticAudio: Audio Generation and Editing in Semantic Space

In recent years, Text-to-Audio Generation has achieved remarkable progress, offering sound creators powerful tools to transform textual inspirations into vivid audio. However, existing models predominantly operate directly in the acoustic latent space of a Variational Autoencoder (VAE), often leading to suboptimal alignment between generated audio and textual descriptions. In this paper, we introduce SemanticAudio, a novel framework that conducts both audio generation and editing directly in a high-level semantic space. We define this semantic space as a compact representation capturing the global identity and temporal sequence of sound events, distinct from fine-grained acoustic details. SemanticAudio employs a two-stage Flow Matching architecture: the Semantic Planner first generates these compact semantic features to sketch the global semantic layout, and the Acoustic Synthesizer subsequently produces high-fidelity acoustic latents conditioned on this semantic plan. Leveraging this decoupled design, we further introduce a training-free text-guided editing mechanism that enables precise attribute-level modifications on general audio without retraining. Specifically, this is achieved by steering the semantic generation trajectory via the difference of velocity fields derived from source and target text prompts. Extensive experiments demonstrate that SemanticAudio surpasses existing mainstream approaches in semantic alignment. Demo available at: https://semanticaudio1.github.io/

DeepNuParc: A Novel Deep Clustering Framework for Fine-scale Parcellation of Brain Nuclei Using Diffusion MRI Tractography

Brain nuclei are clusters of anatomically distinct neurons that serve as important hubs for processing and relaying information in various neural circuits. Fine-scale parcellation of the brain nuclei is vital for a comprehensive understanding of its anatomico-functional correlations. Diffusion MRI tractography is an advanced imaging technique that can estimate the brain's white matter structural connectivity to potentially reveal the topography of the nuclei of interest for studying its subdivisions. In this work, we present a deep clustering pipeline, namely DeepNuParc, to perform automated, fine-scale parcellation of brain nuclei using diffusion MRI tractography. First, we incorporate a newly proposed deep learning approach to enable accurate segmentation of the nuclei of interest directly on the dMRI data. Next, we design a novel streamline clustering-based structural connectivity feature for a robust representation of voxels within the nuclei. Finally, we improve the popular joint dimensionality reduction and k-means clustering approach to enable nuclei parcellation at a finer scale. We demonstrate DeepNuParc on two important brain structures, i.e. the amygdala and the thalamus, that are known to have multiple anatomically and functionally distinct nuclei subdivisions. Experimental results show that DeepNuParc enables consistent parcellation of the nuclei into multiple parcels across multiple subjects and achieves good correspondence with the widely used coarse-scale atlases. Our codes are available at https://github.com/HarlandZZC/deep_nuclei_parcellation.

A Novel Deep Clustering Framework for Fine-Scale Parcellation of Amygdala Using dMRI Tractography

The amygdala plays a vital role in emotional processing and exhibits structural diversity that necessitates fine-scale parcellation for a comprehensive understanding of its anatomico-functional correlations. Diffusion MRI tractography is an advanced imaging technique that can estimate the brain's white matter structural connectivity to potentially reveal the topography of the amygdala for studying its subdivisions. In this work, we present a deep clustering pipeline to perform automated, fine-scale parcellation of the amygdala using diffusion MRI tractography. First, we incorporate a newly proposed deep learning approach to enable accurate segmentation of the amygdala directly on the dMRI data. Next, we design a novel streamline clustering-based structural connectivity feature for a robust representation of voxels within the amygdala. Finally, we improve the popular joint dimensionality reduction and k-means clustering approach to enable amygdala parcellation at a finer scale. With the proposed method, we obtain nine unique amygdala parcels. Experiments show that these parcels can be consistently identified across subjects and have good correspondence to the widely used coarse-scale amygdala parcellation.