DICE: Discrete Inversion Enabling Controllable Editing for Multinomial Diffusion and Masked Generative Models

Discrete diffusion models have achieved success in tasks like image generation and masked language modeling but face limitations in controlled content editing. We introduce DICE (Discrete Inversion for Controllable Editing), the first approach to enable precise inversion for discrete diffusion models, including multinomial diffusion and masked generative models. By recording noise sequences and masking patterns during the reverse diffusion process, DICE enables accurate reconstruction and flexible editing of discrete data without the need for predefined masks or attention manipulation. We demonstrate the effectiveness of DICE across both image and text domains, evaluating it on models such as VQ-Diffusion, Paella, and RoBERTa. Our results show that DICE preserves high data fidelity while enhancing editing capabilities, offering new opportunities for fine-grained content manipulation in discrete spaces. For project webpage, see https://hexiaoxiao-cs.github.io/DICE/.

Reconstruction of Particle Flow Energy Distribution Using Deep Learning Algorithms

In high-energy particle physics, extracting information from complex detector signals is crucial for energy reconstruction. Recent advancements involve using deep learning to process calorimeter images from various sub-detectors in experiments like the Large Hadron Collider (LHC) for energy map reconstruction. This paper compares classical algorithms\-MLP, CNN, U-Net, and RNN\-with variants that include self-attention and 3D convolution modules to evaluate their effectiveness in reconstructing the initial energy distribution. Additionally, a test dataset of jet events is utilized to analyze and compare models' performance in handling anomalous high-energy events. The analysis highlights the effectiveness of deep learning techniques for energy image reconstruction and explores their potential in this area.

$ε$-VAE: Denoising as Visual Decoding

In generative modeling, tokenization simplifies complex data into compact, structured representations, creating a more efficient, learnable space. For high-dimensional visual data, it reduces redundancy and emphasizes key features for high-quality generation. Current visual tokenization methods rely on a traditional autoencoder framework, where the encoder compresses data into latent representations, and the decoder reconstructs the original input. In this work, we offer a new perspective by proposing denoising as decoding, shifting from single-step reconstruction to iterative refinement. Specifically, we replace the decoder with a diffusion process that iteratively refines noise to recover the original image, guided by the latents provided by the encoder. We evaluate our approach by assessing both reconstruction (rFID) and generation quality (FID), comparing it to state-of-the-art autoencoding approach. We hope this work offers new insights into integrating iterative generation and autoencoding for improved compression and generation.

StraightTrack: Towards Mixed Reality Navigation System for Percutaneous K-wire Insertion

In percutaneous pelvic trauma surgery, accurate placement of Kirschner wires (K-wires) is crucial to ensure effective fracture fixation and avoid complications due to breaching the cortical bone along an unsuitable trajectory. Surgical navigation via mixed reality (MR) can help achieve precise wire placement in a low-profile form factor. Current approaches in this domain are as yet unsuitable for real-world deployment because they fall short of guaranteeing accurate visual feedback due to uncontrolled bending of the wire. To ensure accurate feedback, we introduce StraightTrack, an MR navigation system designed for percutaneous wire placement in complex anatomy. StraightTrack features a marker body equipped with a rigid access cannula that mitigates wire bending due to interactions with soft tissue and a covered bony surface. Integrated with an Optical See-Through Head-Mounted Display (OST HMD) capable of tracking the cannula body, StraightTrack offers real-time 3D visualization and guidance without external trackers, which are prone to losing line-of-sight. In phantom experiments with two experienced orthopedic surgeons, StraightTrack improves wire placement accuracy, achieving the ideal trajectory within $5.26 \pm 2.29$ mm and $2.88 \pm 1.49$ degree, compared to over 12.08 mm and 4.07 degree for comparable methods. As MR navigation systems continue to mature, StraightTrack realizes their potential for internal fracture fixation and other percutaneous orthopedic procedures.

Understanding the Benefits of SimCLR Pre-Training in Two-Layer Convolutional Neural Networks

SimCLR is one of the most popular contrastive learning methods for vision tasks. It pre-trains deep neural networks based on a large amount of unlabeled data by teaching the model to distinguish between positive and negative pairs of augmented images. It is believed that SimCLR can pre-train a deep neural network to learn efficient representations that can lead to a better performance of future supervised fine-tuning. Despite its effectiveness, our theoretical understanding of the underlying mechanisms of SimCLR is still limited. In this paper, we theoretically introduce a case study of the SimCLR method. Specifically, we consider training a two-layer convolutional neural network (CNN) to learn a toy image data model. We show that, under certain conditions on the number of labeled data, SimCLR pre-training combined with supervised fine-tuning achieves almost optimal test loss. Notably, the label complexity for SimCLR pre-training is far less demanding compared to direct training on supervised data. Our analysis sheds light on the benefits of SimCLR in learning with fewer labels.

Solving Integrated Process Planning and Scheduling Problem via Graph Neural Network Based Deep Reinforcement Learning

The Integrated Process Planning and Scheduling (IPPS) problem combines process route planning and shop scheduling to achieve high efficiency in manufacturing and maximize resource utilization, which is crucial for modern manufacturing systems. Traditional methods using Mixed Integer Linear Programming (MILP) and heuristic algorithms can not well balance solution quality and speed when solving IPPS. In this paper, we propose a novel end-to-end Deep Reinforcement Learning (DRL) method. We model the IPPS problem as a Markov Decision Process (MDP) and employ a Heterogeneous Graph Neural Network (GNN) to capture the complex relationships among operations, machines, and jobs. To optimize the scheduling strategy, we use Proximal Policy Optimization (PPO). Experimental results show that, compared to traditional methods, our approach significantly improves solution efficiency and quality in large-scale IPPS instances, providing superior scheduling strategies for modern intelligent manufacturing systems.

MagicMan: Generative Novel View Synthesis of Humans with 3D-Aware Diffusion and Iterative Refinement

Existing works in single-image human reconstruction suffer from weak generalizability due to insufficient training data or 3D inconsistencies for a lack of comprehensive multi-view knowledge. In this paper, we introduce MagicMan, a human-specific multi-view diffusion model designed to generate high-quality novel view images from a single reference image. As its core, we leverage a pre-trained 2D diffusion model as the generative prior for generalizability, with the parametric SMPL-X model as the 3D body prior to promote 3D awareness. To tackle the critical challenge of maintaining consistency while achieving dense multi-view generation for improved 3D human reconstruction, we first introduce hybrid multi-view attention to facilitate both efficient and thorough information interchange across different views. Additionally, we present a geometry-aware dual branch to perform concurrent generation in both RGB and normal domains, further enhancing consistency via geometry cues. Last but not least, to address ill-shaped issues arising from inaccurate SMPL-X estimation that conflicts with the reference image, we propose a novel iterative refinement strategy, which progressively optimizes SMPL-X accuracy while enhancing the quality and consistency of the generated multi-views. Extensive experimental results demonstrate that our method significantly outperforms existing approaches in both novel view synthesis and subsequent 3D human reconstruction tasks.

Imagen 3

We introduce Imagen 3, a latent diffusion model that generates high quality images from text prompts. We describe our quality and responsibility evaluations. Imagen 3 is preferred over other state-of-the-art (SOTA) models at the time of evaluation. In addition, we discuss issues around safety and representation, as well as methods we used to minimize the potential harm of our models.

MetaEnzyme: Meta Pan-Enzyme Learning for Task-Adaptive Redesign

Enzyme design plays a crucial role in both industrial production and biology. However, this field faces challenges due to the lack of comprehensive benchmarks and the complexity of enzyme design tasks, leading to a dearth of systematic research. Consequently, computational enzyme design is relatively overlooked within the broader protein domain and remains in its early stages. In this work, we address these challenges by introducing MetaEnzyme, a staged and unified enzyme design framework. We begin by employing a cross-modal structure-to-sequence transformation architecture, as the feature-driven starting point to obtain initial robust protein representation. Subsequently, we leverage domain adaptive techniques to generalize specific enzyme design tasks under low-resource conditions. MetaEnzyme focuses on three fundamental low-resource enzyme redesign tasks: functional design (FuncDesign), mutation design (MutDesign), and sequence generation design (SeqDesign). Through novel unified paradigm and enhanced representation capabilities, MetaEnzyme demonstrates adaptability to diverse enzyme design tasks, yielding outstanding results. Wet lab experiments further validate these findings, reinforcing the efficacy of the redesign process.

A Reference-Based 3D Semantic-Aware Framework for Accurate Local Facial Attribute Editing

Facial attribute editing plays a crucial role in synthesizing realistic faces with specific characteristics while maintaining realistic appearances. Despite advancements, challenges persist in achieving precise, 3D-aware attribute modifications, which are crucial for consistent and accurate representations of faces from different angles. Current methods struggle with semantic entanglement and lack effective guidance for incorporating attributes while maintaining image integrity. To address these issues, we introduce a novel framework that merges the strengths of latent-based and reference-based editing methods. Our approach employs a 3D GAN inversion technique to embed attributes from the reference image into a tri-plane space, ensuring 3D consistency and realistic viewing from multiple perspectives. We utilize blending techniques and predicted semantic masks to locate precise edit regions, merging them with the contextual guidance from the reference image. A coarse-to-fine inpainting strategy is then applied to preserve the integrity of untargeted areas, significantly enhancing realism. Our evaluations demonstrate superior performance across diverse editing tasks, validating our framework's effectiveness in realistic and applicable facial attribute editing.