Implicit Regression in Subspace for High-Sensitivity CEST Imaging

Chemical Exchange Saturation Transfer (CEST) MRI demonstrates its capability in significantly enhancing the detection of proteins and metabolites with low concentrations through exchangeable protons. The clinical application of CEST, however, is constrained by its low contrast and low signal-to-noise ratio (SNR) in the acquired data. Denoising, as one of the post-processing stages for CEST data, can effectively improve the accuracy of CEST quantification. In this work, by modeling spatial variant z-spectrums into low-dimensional subspace, we introduce Implicit Regression in Subspace (IRIS), which is an unsupervised denoising algorithm utilizing the excellent property of implicit neural representation for continuous mapping. Experiments conducted on both synthetic and in-vivo data demonstrate that our proposed method surpasses other CEST denoising methods regarding both qualitative and quantitative performance.

DMNR: Unsupervised De-noising of Point Clouds Corrupted by Airborne Particles

LiDAR sensors are critical for autonomous driving and robotics applications due to their ability to provide accurate range measurements and their robustness to lighting conditions. However, airborne particles, such as fog, rain, snow, and dust, will degrade its performance and it is inevitable to encounter these inclement environmental conditions outdoors. It would be a straightforward approach to remove them by supervised semantic segmentation. But annotating these particles point wisely is too laborious. To address this problem and enhance the perception under inclement conditions, we develop two dynamic filtering methods called Dynamic Multi-threshold Noise Removal (DMNR) and DMNR-H by accurate analysis of the position distribution and intensity characteristics of noisy points and clean points on publicly available WADS and DENSE datasets. Both DMNR and DMNR-H outperform state-of-the-art unsupervised methods by a significant margin on the two datasets and are slightly better than supervised deep learning-based methods. Furthermore, our methods are more robust to different LiDAR sensors and airborne particles, such as snow and fog.

EBM Life Cycle: MCMC Strategies for Synthesis, Defense, and Density Modeling

This work presents strategies to learn an Energy-Based Model (EBM) according to the desired length of its MCMC sampling trajectories. MCMC trajectories of different lengths correspond to models with different purposes. Our experiments cover three different trajectory magnitudes and learning outcomes: 1) shortrun sampling for image generation; 2) midrun sampling for classifier-agnostic adversarial defense; and 3) longrun sampling for principled modeling of image probability densities. To achieve these outcomes, we introduce three novel methods of MCMC initialization for negative samples used in Maximum Likelihood (ML) learning. With standard network architectures and an unaltered ML objective, our MCMC initialization methods alone enable significant performance gains across the three applications that we investigate. Our results include state-of-the-art FID scores for unnormalized image densities on the CIFAR-10 and ImageNet datasets; state-of-the-art adversarial defense on CIFAR-10 among purification methods and the first EBM defense on ImageNet; and scalable techniques for learning valid probability densities. Code for this project can be found at https://github.com/point0bar1/ebm-life-cycle.