A Reversible Solver for Diffusion SDEs

Diffusion models have quickly become the state-of-the-art for generation tasks across many different data modalities. An important ability of diffusion models is the ability to encode samples from the data distribution back into the sampling prior distribution. This is useful for performing alterations to real data samples along with guided generation via the continuous adjoint equations. We propose an algebraically reversible solver for diffusion SDEs that can exactly invert real data samples into the prior distribution.

Not All Frame Features Are Equal: Video-to-4D Generation via Decoupling Dynamic-Static Features

Recently, the generation of dynamic 3D objects from a video has shown impressive results. Existing methods directly optimize Gaussians using whole information in frames. However, when dynamic regions are interwoven with static regions within frames, particularly if the static regions account for a large proportion, existing methods often overlook information in dynamic regions and are prone to overfitting on static regions. This leads to producing results with blurry textures. We consider that decoupling dynamic-static features to enhance dynamic representations can alleviate this issue. Thus, we propose a dynamic-static feature decoupling module (DSFD). Along temporal axes, it regards the portions of current frame features that possess significant differences relative to reference frame features as dynamic features. Conversely, the remaining parts are the static features. Then, we acquire decoupled features driven by dynamic features and current frame features. Moreover, to further enhance the dynamic representation of decoupled features from different viewpoints and ensure accurate motion prediction, we design a temporal-spatial similarity fusion module (TSSF). Along spatial axes, it adaptively selects a similar information of dynamic regions. Hinging on the above, we construct a novel approach, DS4D. Experimental results verify our method achieves state-of-the-art (SOTA) results in video-to-4D. In addition, the experiments on a real-world scenario dataset demonstrate its effectiveness on the 4D scene. Our code will be publicly available.

Greed is Good: Guided Generation from a Greedy Perspective

Training-free guided generation is a widely used and powerful technique that allows the end user to exert further control over the generative process of diffusion models. In this work, we explore the guided generation from the perspective of optimizing the solution trajectory of a neural differential equation in a greedy manner. We present such a strategy as a unifying view on training-free guidance by showing that the greedy strategy is a first-order discretization of end-to-end optimization techniques. We show that a greedy guidance strategy makes good decisions and compare it to a guidance strategy using the ideal gradients found via the continuous adjoint equations. We then show how other popular training-free guidance strategies can be viewed in a unified manner from this perspective.

Text-Driven Tumor Synthesis

Tumor synthesis can generate examples that AI often misses or over-detects, improving AI performance by training on these challenging cases. However, existing synthesis methods, which are typically unconditional -- generating images from random variables -- or conditioned only by tumor shapes, lack controllability over specific tumor characteristics such as texture, heterogeneity, boundaries, and pathology type. As a result, the generated tumors may be overly similar or duplicates of existing training data, failing to effectively address AI's weaknesses. We propose a new text-driven tumor synthesis approach, termed TextoMorph, that provides textual control over tumor characteristics. This is particularly beneficial for examples that confuse the AI the most, such as early tumor detection (increasing Sensitivity by +8.5%), tumor segmentation for precise radiotherapy (increasing DSC by +6.3%), and classification between benign and malignant tumors (improving Sensitivity by +8.2%). By incorporating text mined from radiology reports into the synthesis process, we increase the variability and controllability of the synthetic tumors to target AI's failure cases more precisely. Moreover, TextoMorph uses contrastive learning across different texts and CT scans, significantly reducing dependence on scarce image-report pairs (only 141 pairs used in this study) by leveraging a large corpus of 34,035 radiology reports. Finally, we have developed rigorous tests to evaluate synthetic tumors, including Text-Driven Visual Turing Test and Radiomics Pattern Analysis, showing that our synthetic tumors is realistic and diverse in texture, heterogeneity, boundaries, and pathology.

Design2GarmentCode: Turning Design Concepts to Tangible Garments Through Program Synthesis

Sewing patterns, the essential blueprints for fabric cutting and tailoring, act as a crucial bridge between design concepts and producible garments. However, existing uni-modal sewing pattern generation models struggle to effectively encode complex design concepts with a multi-modal nature and correlate them with vectorized sewing patterns that possess precise geometric structures and intricate sewing relations. In this work, we propose a novel sewing pattern generation approach Design2GarmentCode based on Large Multimodal Models (LMMs), to generate parametric pattern-making programs from multi-modal design concepts. LMM offers an intuitive interface for interpreting diverse design inputs, while pattern-making programs could serve as well-structured and semantically meaningful representations of sewing patterns, and act as a robust bridge connecting the cross-domain pattern-making knowledge embedded in LMMs with vectorized sewing patterns. Experimental results demonstrate that our method can flexibly handle various complex design expressions such as images, textual descriptions, designer sketches, or their combinations, and convert them into size-precise sewing patterns with correct stitches. Compared to previous methods, our approach significantly enhances training efficiency, generation quality, and authoring flexibility. Our code and data will be publicly available.

Maya: An Instruction Finetuned Multilingual Multimodal Model

The rapid development of large Vision-Language Models (VLMs) has led to impressive results on academic benchmarks, primarily in widely spoken languages. However, significant gaps remain in the ability of current VLMs to handle low-resource languages and varied cultural contexts, largely due to a lack of high-quality, diverse, and safety-vetted data. Consequently, these models often struggle to understand low-resource languages and cultural nuances in a manner free from toxicity. To address these limitations, we introduce Maya, an open-source Multimodal Multilingual model. Our contributions are threefold: 1) a multilingual image-text pretraining dataset in eight languages, based on the LLaVA pretraining dataset; 2) a thorough analysis of toxicity within the LLaVA dataset, followed by the creation of a novel toxicity-free version across eight languages; and 3) a multilingual image-text model supporting these languages, enhancing cultural and linguistic comprehension in vision-language tasks. Code available at https://github.com/nahidalam/maya.

ReconDreamer: Crafting World Models for Driving Scene Reconstruction via Online Restoration

Closed-loop simulation is crucial for end-to-end autonomous driving. Existing sensor simulation methods (e.g., NeRF and 3DGS) reconstruct driving scenes based on conditions that closely mirror training data distributions. However, these methods struggle with rendering novel trajectories, such as lane changes. Recent works have demonstrated that integrating world model knowledge alleviates these issues. Despite their efficiency, these approaches still encounter difficulties in the accurate representation of more complex maneuvers, with multi-lane shifts being a notable example. Therefore, we introduce ReconDreamer, which enhances driving scene reconstruction through incremental integration of world model knowledge. Specifically, DriveRestorer is proposed to mitigate artifacts via online restoration. This is complemented by a progressive data update strategy designed to ensure high-quality rendering for more complex maneuvers. To the best of our knowledge, ReconDreamer is the first method to effectively render in large maneuvers. Experimental results demonstrate that ReconDreamer outperforms Street Gaussians in the NTA-IoU, NTL-IoU, and FID, with relative improvements by 24.87%, 6.72%, and 29.97%. Furthermore, ReconDreamer surpasses DriveDreamer4D with PVG during large maneuver rendering, as verified by a relative improvement of 195.87% in the NTA-IoU metric and a comprehensive user study.

Addressing Asynchronicity in Clinical Multimodal Fusion via Individualized Chest X-ray Generation

Integrating multi-modal clinical data, such as electronic health records (EHR) and chest X-ray images (CXR), is particularly beneficial for clinical prediction tasks. However, in a temporal setting, multi-modal data are often inherently asynchronous. EHR can be continuously collected but CXR is generally taken with a much longer interval due to its high cost and radiation dose. When clinical prediction is needed, the last available CXR image might have been outdated, leading to suboptimal predictions. To address this challenge, we propose DDL-CXR, a method that dynamically generates an up-to-date latent representation of the individualized CXR images. Our approach leverages latent diffusion models for patient-specific generation strategically conditioned on a previous CXR image and EHR time series, providing information regarding anatomical structures and disease progressions, respectively. In this way, the interaction across modalities could be better captured by the latent CXR generation process, ultimately improving the prediction performance. Experiments using MIMIC datasets show that the proposed model could effectively address asynchronicity in multimodal fusion and consistently outperform existing methods.

Geometry-Aware Generative Autoencoders for Warped Riemannian Metric Learning and Generative Modeling on Data Manifolds

Rapid growth of high-dimensional datasets in fields such as single-cell RNA sequencing and spatial genomics has led to unprecedented opportunities for scientific discovery, but it also presents unique computational and statistical challenges. Traditional methods struggle with geometry-aware data generation, interpolation along meaningful trajectories, and transporting populations via feasible paths. To address these issues, we introduce Geometry-Aware Generative Autoencoder (GAGA), a novel framework that combines extensible manifold learning with generative modeling. GAGA constructs a neural network embedding space that respects the intrinsic geometries discovered by manifold learning and learns a novel warped Riemannian metric on the data space. This warped metric is derived from both the points on the data manifold and negative samples off the manifold, allowing it to characterize a meaningful geometry across the entire latent space. Using this metric, GAGA can uniformly sample points on the manifold, generate points along geodesics, and interpolate between populations across the learned manifold. GAGA shows competitive performance in simulated and real world datasets, including a 30% improvement over the state-of-the-art methods in single-cell population-level trajectory inference.

DiffKillR: Killing and Recreating Diffeomorphisms for Cell Annotation in Dense Microscopy Images

The proliferation of digital microscopy images, driven by advances in automated whole slide scanning, presents significant opportunities for biomedical research and clinical diagnostics. However, accurately annotating densely packed information in these images remains a major challenge. To address this, we introduce DiffKillR, a novel framework that reframes cell annotation as the combination of archetype matching and image registration tasks. DiffKillR employs two complementary neural networks: one that learns a diffeomorphism-invariant feature space for robust cell matching and another that computes the precise warping field between cells for annotation mapping. Using a small set of annotated archetypes, DiffKillR efficiently propagates annotations across large microscopy images, reducing the need for extensive manual labeling. More importantly, it is suitable for any type of pixel-level annotation. We will discuss the theoretical properties of DiffKillR and validate it on three microscopy tasks, demonstrating its advantages over existing supervised, semi-supervised, and unsupervised methods.