SEG-SAM: Semantic-Guided SAM for Unified Medical Image Segmentation

Recently, developing unified medical image segmentation models gains increasing attention, especially with the advent of the Segment Anything Model (SAM). SAM has shown promising binary segmentation performance in natural domains, however, transferring it to the medical domain remains challenging, as medical images often possess substantial inter-category overlaps. To address this, we propose the SEmantic-Guided SAM (SEG-SAM), a unified medical segmentation model that incorporates semantic medical knowledge to enhance medical segmentation performance. First, to avoid the potential conflict between binary and semantic predictions, we introduce a semantic-aware decoder independent of SAM's original decoder, specialized for both semantic segmentation on the prompted object and classification on unprompted objects in images. To further enhance the model's semantic understanding, we solicit key characteristics of medical categories from large language models and incorporate them into SEG-SAM through a text-to-vision semantic module, adaptively transferring the language information into the visual segmentation task. In the end, we introduce the cross-mask spatial alignment strategy to encourage greater overlap between the predicted masks from SEG-SAM's two decoders, thereby benefiting both predictions. Extensive experiments demonstrate that SEG-SAM outperforms state-of-the-art SAM-based methods in unified binary medical segmentation and task-specific methods in semantic medical segmentation, showcasing promising results and potential for broader medical applications.

Learning Flow Fields in Attention for Controllable Person Image Generation

Controllable person image generation aims to generate a person image conditioned on reference images, allowing precise control over the person's appearance or pose. However, prior methods often distort fine-grained textural details from the reference image, despite achieving high overall image quality. We attribute these distortions to inadequate attention to corresponding regions in the reference image. To address this, we thereby propose learning flow fields in attention (Leffa), which explicitly guides the target query to attend to the correct reference key in the attention layer during training. Specifically, it is realized via a regularization loss on top of the attention map within a diffusion-based baseline. Our extensive experiments show that Leffa achieves state-of-the-art performance in controlling appearance (virtual try-on) and pose (pose transfer), significantly reducing fine-grained detail distortion while maintaining high image quality. Additionally, we show that our loss is model-agnostic and can be used to improve the performance of other diffusion models.

Optimizing Dense Visual Predictions Through Multi-Task Coherence and Prioritization

Multi-Task Learning (MTL) involves the concurrent training of multiple tasks, offering notable advantages for dense prediction tasks in computer vision. MTL not only reduces training and inference time as opposed to having multiple single-task models, but also enhances task accuracy through the interaction of multiple tasks. However, existing methods face limitations. They often rely on suboptimal cross-task interactions, resulting in task-specific predictions with poor geometric and predictive coherence. In addition, many approaches use inadequate loss weighting strategies, which do not address the inherent variability in task evolution during training. To overcome these challenges, we propose an advanced MTL model specifically designed for dense vision tasks. Our model leverages state-of-the-art vision transformers with task-specific decoders. To enhance cross-task coherence, we introduce a trace-back method that improves both cross-task geometric and predictive features. Furthermore, we present a novel dynamic task balancing approach that projects task losses onto a common scale and prioritizes more challenging tasks during training. Extensive experiments demonstrate the superiority of our method, establishing new state-of-the-art performance across two benchmark datasets. The code is available at:https://github.com/Klodivio355/MT-CP

Aligning Few-Step Diffusion Models with Dense Reward Difference Learning

Aligning diffusion models with downstream objectives is essential for their practical applications. However, standard alignment methods often struggle with step generalization when directly applied to few-step diffusion models, leading to inconsistent performance across different denoising step scenarios. To address this, we introduce Stepwise Diffusion Policy Optimization (SDPO), a novel alignment method tailored for few-step diffusion models. Unlike prior approaches that rely on a single sparse reward from only the final step of each denoising trajectory for trajectory-level optimization, SDPO incorporates dense reward feedback at every intermediate step. By learning the differences in dense rewards between paired samples, SDPO facilitates stepwise optimization of few-step diffusion models, ensuring consistent alignment across all denoising steps. To promote stable and efficient training, SDPO introduces an online reinforcement learning framework featuring several novel strategies designed to effectively exploit the stepwise granularity of dense rewards. Experimental results demonstrate that SDPO consistently outperforms prior methods in reward-based alignment across diverse step configurations, underscoring its robust step generalization capabilities. Code is avaliable at https://github.com/ZiyiZhang27/sdpo.

An investigation into the causes of race bias in AI-based cine CMR segmentation

Artificial intelligence (AI) methods are being used increasingly for the automated segmentation of cine cardiac magnetic resonance (CMR) imaging. However, these methods have been shown to be subject to race bias, i.e. they exhibit different levels of performance for different races depending on the (im)balance of the data used to train the AI model. In this paper we investigate the source of this bias, seeking to understand its root cause(s) so that it can be effectively mitigated. We perform a series of classification and segmentation experiments on short-axis cine CMR images acquired from Black and White subjects from the UK Biobank and apply AI interpretability methods to understand the results. In the classification experiments, we found that race can be predicted with high accuracy from the images alone, but less accurately from ground truth segmentations, suggesting that the distributional shift between races, which is often the cause of AI bias, is mostly image-based rather than segmentation-based. The interpretability methods showed that most attention in the classification models was focused on non-heart regions, such as subcutaneous fat. Cropping the images tightly around the heart reduced classification accuracy to around chance level. Similarly, race can be predicted from the latent representations of a biased segmentation model, suggesting that race information is encoded in the model. Cropping images tightly around the heart reduced but did not eliminate segmentation bias. We also investigate the influence of possible confounders on the bias observed.

OpenPSG: Open-set Panoptic Scene Graph Generation via Large Multimodal Models

Panoptic Scene Graph Generation (PSG) aims to segment objects and recognize their relations, enabling the structured understanding of an image. Previous methods focus on predicting predefined object and relation categories, hence limiting their applications in the open world scenarios. With the rapid development of large multimodal models (LMMs), significant progress has been made in open-set object detection and segmentation, yet open-set relation prediction in PSG remains unexplored. In this paper, we focus on the task of open-set relation prediction integrated with a pretrained open-set panoptic segmentation model to achieve true open-set panoptic scene graph generation (OpenPSG). Our OpenPSG leverages LMMs to achieve open-set relation prediction in an autoregressive manner. We introduce a relation query transformer to efficiently extract visual features of object pairs and estimate the existence of relations between them. The latter can enhance the prediction efficiency by filtering irrelevant pairs. Finally, we design the generation and judgement instructions to perform open-set relation prediction in PSG autoregressively. To our knowledge, we are the first to propose the open-set PSG task. Extensive experiments demonstrate that our method achieves state-of-the-art performance in open-set relation prediction and panoptic scene graph generation. Code is available at \url{https://github.com/franciszzj/OpenPSG}.

Bootstrapping Vision-language Models for Self-supervised Remote Physiological Measurement

Facial video-based remote physiological measurement is a promising research area for detecting human vital signs (e.g., heart rate, respiration frequency) in a non-contact way. Conventional approaches are mostly supervised learning, requiring extensive collections of facial videos and synchronously recorded photoplethysmography (PPG) signals. To tackle it, self-supervised learning has recently gained attentions; due to the lack of ground truth PPG signals, its performance is however limited. In this paper, we propose a novel self-supervised framework that successfully integrates the popular vision-language models (VLMs) into the remote physiological measurement task. Given a facial video, we first augment its positive and negative video samples with varying rPPG signal frequencies. Next, we introduce a frequency-oriented vision-text pair generation method by carefully creating contrastive spatio-temporal maps from positive and negative samples and designing proper text prompts to describe their relative ratios of signal frequencies. A pre-trained VLM is employed to extract features for these formed vision-text pairs and estimate rPPG signals thereafter. We develop a series of generative and contrastive learning mechanisms to optimize the VLM, including the text-guided visual map reconstruction task, the vision-text contrastive learning task, and the frequency contrastive and ranking task. Overall, our method for the first time adapts VLMs to digest and align the frequency-related knowledge in vision and text modalities. Extensive experiments on four benchmark datasets demonstrate that it significantly outperforms state of the art self-supervised methods.

CholecInstanceSeg: A Tool Instance Segmentation Dataset for Laparoscopic Surgery

In laparoscopic and robotic surgery, precise tool instance segmentation is an essential technology for advanced computer-assisted interventions. Although publicly available procedures of routine surgeries exist, they often lack comprehensive annotations for tool instance segmentation. Additionally, the majority of standard datasets for tool segmentation are derived from porcine(pig) surgeries. To address this gap, we introduce CholecInstanceSeg, the largest open-access tool instance segmentation dataset to date. Derived from the existing CholecT50 and Cholec80 datasets, CholecInstanceSeg provides novel annotations for laparoscopic cholecystectomy procedures in patients. Our dataset comprises 41.9k annotated frames extracted from 85 clinical procedures and 64.4k tool instances, each labelled with semantic masks and instance IDs. To ensure the reliability of our annotations, we perform extensive quality control, conduct label agreement statistics, and benchmark the segmentation results with various instance segmentation baselines. CholecInstanceSeg aims to advance the field by offering a comprehensive and high-quality open-access dataset for the development and evaluation of tool instance segmentation algorithms.

Memory-guided Network with Uncertainty-based Feature Augmentation for Few-shot Semantic Segmentation

The performance of supervised semantic segmentation methods highly relies on the availability of large-scale training data. To alleviate this dependence, few-shot semantic segmentation (FSS) is introduced to leverage the model trained on base classes with sufficient data into the segmentation of novel classes with few data. FSS methods face the challenge of model generalization on novel classes due to the distribution shift between base and novel classes. To overcome this issue, we propose a class-shared memory (CSM) module consisting of a set of learnable memory vectors. These memory vectors learn elemental object patterns from base classes during training whilst re-encoding query features during both training and inference, thereby improving the distribution alignment between base and novel classes. Furthermore, to cope with the performance degradation resulting from the intra-class variance across images, we introduce an uncertainty-based feature augmentation (UFA) module to produce diverse query features during training for improving the model's robustness. We integrate CSM and UFA into representative FSS works, with experimental results on the widely-used PASCAL-5$^i$ and COCO-20$^i$ datasets demonstrating the superior performance of ours over state of the art.

Large Model driven Radiology Report Generation with Clinical Quality Reinforcement Learning

Radiology report generation (RRG) has attracted significant attention due to its potential to reduce the workload of radiologists. Current RRG approaches are still unsatisfactory against clinical standards. This paper introduces a novel RRG method, \textbf{LM-RRG}, that integrates large models (LMs) with clinical quality reinforcement learning to generate accurate and comprehensive chest X-ray radiology reports. Our method first designs a large language model driven feature extractor to analyze and interpret different regions of the chest X-ray image, emphasizing specific regions with medical significance. Next, based on the large model's decoder, we develop a multimodal report generator that leverages multimodal prompts from visual features and textual instruction to produce the radiology report in an auto-regressive way. Finally, to better reflect the clinical significant and insignificant errors that radiologists would normally assign in the report, we introduce a novel clinical quality reinforcement learning strategy. It utilizes the radiology report clinical quality (RadCliQ) metric as a reward function in the learning process. Extensive experiments on the MIMIC-CXR and IU-Xray datasets demonstrate the superiority of our method over the state of the art.