AERA Chat: An Interactive Platform for Automated Explainable Student Answer Assessment

Generating rationales that justify scoring decisions has emerged as a promising approach to enhance explainability in the development of automated scoring systems. However, the scarcity of publicly available rationale data and the high cost of annotation have resulted in existing methods typically relying on noisy rationales generated by large language models (LLMs). To address these challenges, we have developed AERA Chat, an interactive platform, to provide visually explained assessment of student answers and streamline the verification of rationales. Users can input questions and student answers to obtain automated, explainable assessment results from LLMs. The platform's innovative visualization features and robust evaluation tools make it useful for educators to assist their marking process, and for researchers to evaluate assessment performance and quality of rationales generated by different LLMs, or as a tool for efficient annotation. We evaluated three rationale generation approaches on our platform to demonstrate its capability.

ExDDI: Explaining Drug-Drug Interaction Predictions with Natural Language

Predicting unknown drug-drug interactions (DDIs) is crucial for improving medication safety. Previous efforts in DDI prediction have typically focused on binary classification or predicting DDI categories, with the absence of explanatory insights that could enhance trust in these predictions. In this work, we propose to generate natural language explanations for DDI predictions, enabling the model to reveal the underlying pharmacodynamics and pharmacokinetics mechanisms simultaneously as making the prediction. To do this, we have collected DDI explanations from DDInter and DrugBank and developed various models for extensive experiments and analysis. Our models can provide accurate explanations for unknown DDIs between known drugs. This paper contributes new tools to the field of DDI prediction and lays a solid foundation for further research on generating explanations for DDI predictions.

PropSAM: A Propagation-Based Model for Segmenting Any 3D Objects in Multi-Modal Medical Images

Volumetric segmentation is crucial for medical imaging but is often constrained by labor-intensive manual annotations and the need for scenario-specific model training. Furthermore, existing general segmentation models are inefficient due to their design and inferential approaches. Addressing this clinical demand, we introduce PropSAM, a propagation-based segmentation model that optimizes the use of 3D medical structure information. PropSAM integrates a CNN-based UNet for intra-slice processing with a Transformer-based module for inter-slice propagation, focusing on structural and semantic continuities to enhance segmentation across various modalities. Distinctively, PropSAM operates on a one-view prompt, such as a 2D bounding box or sketch mask, unlike conventional models that require two-view prompts. It has demonstrated superior performance, significantly improving the Dice Similarity Coefficient (DSC) across 44 medical datasets and various imaging modalities, outperforming models like MedSAM and SegVol with an average DSC improvement of 18.1%. PropSAM also maintains stable predictions despite prompt deviations and varying propagation configurations, confirmed by one-way ANOVA tests with P>0.5985 and P>0.6131, respectively. Moreover, PropSAM's efficient architecture enables faster inference speeds (Wilcoxon rank-sum test, P<0.001) and reduces user interaction time by 37.8% compared to two-view prompt models. Its ability to handle irregular and complex objects with robust performance further demonstrates its potential in clinical settings, facilitating more automated and reliable medical imaging analyses with minimal retraining.

Calibrating LLMs with Preference Optimization on Thought Trees for Generating Rationale in Science Question Scoring

Generating rationales that justify scoring decisions has been a promising way to facilitate explainability in automated scoring systems. However, existing methods do not match the accuracy of classifier-based methods. Plus, the generated rationales often contain hallucinated information. To address these issues, we propose a novel framework capable of generating more faithful rationales and, more importantly, matching performance with classifier-based black-box scoring systems. We first mimic the human assessment process by querying Large Language Models (LLMs) to generate a thought tree. We then summarise intermediate assessment decisions from each thought tree path for creating synthetic rationale data and rationale preference data. Finally, we utilise the generated synthetic data to calibrate LLMs through a two-step training process: supervised fine-tuning and preference optimization. Extensive experimental results demonstrate that our framework achieves a 38% assessment performance improvement in the QWK score compared to prior work while producing higher-quality rationales, as recognised by human evaluators and LLMs. Our work sheds light on the effectiveness of performing preference optimization using synthetic preference data obtained from thought tree paths.

Eliminating Biased Length Reliance of Direct Preference Optimization via Down-Sampled KL Divergence

Direct Preference Optimization (DPO) has emerged as a prominent algorithm for the direct and robust alignment of Large Language Models (LLMs) with human preferences, offering a more straightforward alternative to the complex Reinforcement Learning from Human Feedback (RLHF). Despite its promising efficacy, DPO faces a notable drawback: "verbosity", a common over-optimization phenomenon also observed in RLHF. While previous studies mainly attributed verbosity to biased labels within the data, we propose that the issue also stems from an inherent algorithmic length reliance in DPO. Specifically, we suggest that the discrepancy between sequence-level Kullback-Leibler (KL) divergences between chosen and rejected sequences, used in DPO, results in overestimated or underestimated rewards due to varying token lengths. Empirically, we utilize datasets with different label lengths to demonstrate the presence of biased rewards. We then introduce an effective downsampling approach, named SamPO, to eliminate potential length reliance. Our experimental evaluations, conducted across three LLMs of varying scales and a diverse array of conditional and open-ended benchmarks, highlight the efficacy of SamPO in mitigating verbosity, achieving improvements of 5% to 12% over DPO through debaised rewards. Our codes can be accessed at: https://github.com/LuJunru/SamPO/.

Large Language Models Fall Short: Understanding Complex Relationships in Detective Narratives

Existing datasets for narrative understanding often fail to represent the complexity and uncertainty of relationships in real-life social scenarios. To address this gap, we introduce a new benchmark, Conan, designed for extracting and analysing intricate character relation graphs from detective narratives. Specifically, we designed hierarchical relationship categories and manually extracted and annotated role-oriented relationships from the perspectives of various characters, incorporating both public relationships known to most characters and secret ones known to only a few. Our experiments with advanced Large Language Models (LLMs) like GPT-3.5, GPT-4, and Llama2 reveal their limitations in inferencing complex relationships and handling longer narratives. The combination of the Conan dataset and our pipeline strategy is geared towards understanding the ability of LLMs to comprehend nuanced relational dynamics in narrative contexts.

The Mystery and Fascination of LLMs: A Comprehensive Survey on the Interpretation and Analysis of Emergent Abilities

Understanding emergent abilities, such as in-context learning (ICL) and chain-of-thought (CoT) prompting in large language models (LLMs), is of utmost importance. This importance stems not only from the better utilization of these capabilities across various tasks, but also from the proactive identification and mitigation of potential risks, including concerns of truthfulness, bias, and toxicity, that may arise alongside these capabilities. In this paper, we present a thorough survey on the interpretation and analysis of emergent abilities of LLMs. First, we provide a concise introduction to the background and definition of emergent abilities. Then, we give an overview of advancements from two perspectives: 1) a macro perspective, emphasizing studies on the mechanistic interpretability and delving into the mathematical foundations behind emergent abilities; and 2) a micro-perspective, concerning studies that focus on empirical interpretability by examining factors associated with these abilities. We conclude by highlighting the challenges encountered and suggesting potential avenues for future research. We believe that our work establishes the basis for further exploration into the interpretation of emergent abilities.

NarrativePlay: Interactive Narrative Understanding

In this paper, we introduce NarrativePlay, a novel system that allows users to role-play a fictional character and interact with other characters in narratives such as novels in an immersive environment. We leverage Large Language Models (LLMs) to generate human-like responses, guided by personality traits extracted from narratives. The system incorporates auto-generated visual display of narrative settings, character portraits, and character speech, greatly enhancing user experience. Our approach eschews predefined sandboxes, focusing instead on main storyline events extracted from narratives from the perspective of a user-selected character. NarrativePlay has been evaluated on two types of narratives, detective and adventure stories, where users can either explore the world or improve their favorability with the narrative characters through conversations.

CUE: An Uncertainty Interpretation Framework for Text Classifiers Built on Pre-Trained Language Models

Text classifiers built on Pre-trained Language Models (PLMs) have achieved remarkable progress in various tasks including sentiment analysis, natural language inference, and question-answering. However, the occurrence of uncertain predictions by these classifiers poses a challenge to their reliability when deployed in practical applications. Much effort has been devoted to designing various probes in order to understand what PLMs capture. But few studies have delved into factors influencing PLM-based classifiers' predictive uncertainty. In this paper, we propose a novel framework, called CUE, which aims to interpret uncertainties inherent in the predictions of PLM-based models. In particular, we first map PLM-encoded representations to a latent space via a variational auto-encoder. We then generate text representations by perturbing the latent space which causes fluctuation in predictive uncertainty. By comparing the difference in predictive uncertainty between the perturbed and the original text representations, we are able to identify the latent dimensions responsible for uncertainty and subsequently trace back to the input features that contribute to such uncertainty. Our extensive experiments on four benchmark datasets encompassing linguistic acceptability classification, emotion classification, and natural language inference show the feasibility of our proposed framework. Our source code is available at: https://github.com/lijiazheng99/CUE.

propnet: Propagating 2D Annotation to 3D Segmentation for Gastric Tumors on CT Scans

**Background:** Accurate 3D CT scan segmentation of gastric tumors is pivotal for diagnosis and treatment. The challenges lie in the irregular shapes, blurred boundaries of tumors, and the inefficiency of existing methods. **Purpose:** We conducted a study to introduce a model, utilizing human-guided knowledge and unique modules, to address the challenges of 3D tumor segmentation. **Methods:** We developed the PropNet framework, propagating radiologists' knowledge from 2D annotations to the entire 3D space. This model consists of a proposing stage for coarse segmentation and a refining stage for improved segmentation, using two-way branches for enhanced performance and an up-down strategy for efficiency. **Results:** With 98 patient scans for training and 30 for validation, our method achieves a significant agreement with manual annotation (Dice of 0.803) and improves efficiency. The performance is comparable in different scenarios and with various radiologists' annotations (Dice between 0.785 and 0.803). Moreover, the model shows improved prognostic prediction performance (C-index of 0.620 vs. 0.576) on an independent validation set of 42 patients with advanced gastric cancer. **Conclusions:** Our model generates accurate tumor segmentation efficiently and stably, improving prognostic performance and reducing high-throughput image reading workload. This model can accelerate the quantitative analysis of gastric tumors and enhance downstream task performance.