Peri-AIIMS: Perioperative Artificial Intelligence Driven Integrated Modeling of Surgeries using Anesthetic, Physical and Cognitive Statuses for Predicting Hospital Outcomes

The association between preoperative cognitive status and surgical outcomes is a critical, yet scarcely explored area of research. Linking intraoperative data with postoperative outcomes is a promising and low-cost way of evaluating long-term impacts of surgical interventions. In this study, we evaluated how preoperative cognitive status as measured by the clock drawing test contributed to predicting length of hospital stay, hospital charges, average pain experienced during follow-up, and 1-year mortality over and above intraoperative variables, demographics, preoperative physical status and comorbidities. We expanded our analysis to 6 specific surgical groups where sufficient data was available for cross-validation. The clock drawing images were represented by 10 constructional features discovered by a semi-supervised deep learning algorithm, previously validated to differentiate between dementia and non-dementia patients. Different machine learning models were trained to classify postoperative outcomes in hold-out test sets. The models were compared to their relative performance, time complexity, and interpretability. Shapley Additive Explanations (SHAP) analysis was used to find the most predictive features for classifying different outcomes in different surgical contexts. Relative classification performances achieved by different feature sets showed that the perioperative cognitive dataset which included clock drawing features in addition to intraoperative variables, demographics, and comorbidities served as the best dataset for 12 of 18 possible surgery-outcome combinations...

DeLLiriuM: A large language model for delirium prediction in the ICU using structured EHR

Delirium is an acute confusional state that has been shown to affect up to 31% of patients in the intensive care unit (ICU). Early detection of this condition could lead to more timely interventions and improved health outcomes. While artificial intelligence (AI) models have shown great potential for ICU delirium prediction using structured electronic health records (EHR), most of them have not explored the use of state-of-the-art AI models, have been limited to single hospitals, or have been developed and validated on small cohorts. The use of large language models (LLM), models with hundreds of millions to billions of parameters, with structured EHR data could potentially lead to improved predictive performance. In this study, we propose DeLLiriuM, a novel LLM-based delirium prediction model using EHR data available in the first 24 hours of ICU admission to predict the probability of a patient developing delirium during the rest of their ICU admission. We develop and validate DeLLiriuM on ICU admissions from 104,303 patients pertaining to 195 hospitals across three large databases: the eICU Collaborative Research Database, the Medical Information Mart for Intensive Care (MIMIC)-IV, and the University of Florida Health's Integrated Data Repository. The performance measured by the area under the receiver operating characteristic curve (AUROC) showed that DeLLiriuM outperformed all baselines in two external validation sets, with 0.77 (95% confidence interval 0.76-0.78) and 0.84 (95% confidence interval 0.83-0.85) across 77,543 patients spanning 194 hospitals. To the best of our knowledge, DeLLiriuM is the first LLM-based delirium prediction tool for the ICU based on structured EHR data, outperforming deep learning baselines which employ structured features and can provide helpful information to clinicians for timely interventions.

SeaDATE: Remedy Dual-Attention Transformer with Semantic Alignment via Contrast Learning for Multimodal Object Detection

Multimodal object detection leverages diverse modal information to enhance the accuracy and robustness of detectors. By learning long-term dependencies, Transformer can effectively integrate multimodal features in the feature extraction stage, which greatly improves the performance of multimodal object detection. However, current methods merely stack Transformer-guided fusion techniques without exploring their capability to extract features at various depth layers of network, thus limiting the improvements in detection performance. In this paper, we introduce an accurate and efficient object detection method named SeaDATE. Initially, we propose a novel dual attention Feature Fusion (DTF) module that, under Transformer's guidance, integrates local and global information through a dual attention mechanism, strengthening the fusion of modal features from orthogonal perspectives using spatial and channel tokens. Meanwhile, our theoretical analysis and empirical validation demonstrate that the Transformer-guided fusion method, treating images as sequences of pixels for fusion, performs better on shallow features' detail information compared to deep semantic information. To address this, we designed a contrastive learning (CL) module aimed at learning features of multimodal samples, remedying the shortcomings of Transformer-guided fusion in extracting deep semantic features, and effectively utilizing cross-modal information. Extensive experiments and ablation studies on the FLIR, LLVIP, and M3FD datasets have proven our method to be effective, achieving state-of-the-art detection performance.

FusionSAM: Latent Space driven Segment Anything Model for Multimodal Fusion and Segmentation

Multimodal image fusion and segmentation enhance scene understanding in autonomous driving by integrating data from various sensors. However, current models struggle to efficiently segment densely packed elements in such scenes, due to the absence of comprehensive fusion features that can guide mid-process fine-tuning and focus attention on relevant areas. The Segment Anything Model (SAM) has emerged as a transformative segmentation method. It provides more effective prompts through its flexible prompt encoder, compared to transformers lacking fine-tuned control. Nevertheless, SAM has not been extensively studied in the domain of multimodal fusion for natural images. In this paper, we introduce SAM into multimodal image segmentation for the first time, proposing a novel framework that combines Latent Space Token Generation (LSTG) and Fusion Mask Prompting (FMP) modules to enhance SAM's multimodal fusion and segmentation capabilities. Specifically, we first obtain latent space features of the two modalities through vector quantization and embed them into a cross-attention-based inter-domain fusion module to establish long-range dependencies between modalities. Then, we use these comprehensive fusion features as prompts to guide precise pixel-level segmentation. Extensive experiments on several public datasets demonstrate that the proposed method significantly outperforms SAM and SAM2 in multimodal autonomous driving scenarios, achieving at least 3.9$\%$ higher segmentation mIoU than the state-of-the-art approaches.

FoRA: Low-Rank Adaptation Model beyond Multimodal Siamese Network

Multimodal object detection offers a promising prospect to facilitate robust detection in various visual conditions. However, existing two-stream backbone networks are challenged by complex fusion and substantial parameter increments. This is primarily due to large data distribution biases of multimodal homogeneous information. In this paper, we propose a novel multimodal object detector, named Low-rank Modal Adaptors (LMA) with a shared backbone. The shared parameters enhance the consistency of homogeneous information, while lightweight modal adaptors focus on modality unique features. Furthermore, we design an adaptive rank allocation strategy to adapt to the varying heterogeneity at different feature levels. When applied to two multimodal object detection datasets, experiments validate the effectiveness of our method. Notably, on DroneVehicle, LMA attains a 10.4% accuracy improvement over the state-of-the-art method with a 149M-parameters reduction. The code is available at https://github.com/zyszxhy/FoRA. Our work was submitted to ACM MM in April 2024, but was rejected. We will continue to refine our work and paper writing next, mainly including proof of theory and multi-task applications of FoRA.

Exploring User Retrieval Integration towards Large Language Models for Cross-Domain Sequential Recommendation

Cross-Domain Sequential Recommendation (CDSR) aims to mine and transfer users' sequential preferences across different domains to alleviate the long-standing cold-start issue. Traditional CDSR models capture collaborative information through user and item modeling while overlooking valuable semantic information. Recently, Large Language Model (LLM) has demonstrated powerful semantic reasoning capabilities, motivating us to introduce them to better capture semantic information. However, introducing LLMs to CDSR is non-trivial due to two crucial issues: seamless information integration and domain-specific generation. To this end, we propose a novel framework named URLLM, which aims to improve the CDSR performance by exploring the User Retrieval approach and domain grounding on LLM simultaneously. Specifically, we first present a novel dual-graph sequential model to capture the diverse information, along with an alignment and contrastive learning method to facilitate domain knowledge transfer. Subsequently, a user retrieve-generation model is adopted to seamlessly integrate the structural information into LLM, fully harnessing its emergent inferencing ability. Furthermore, we propose a domain-specific strategy and a refinement module to prevent out-of-domain generation. Extensive experiments on Amazon demonstrated the information integration and domain-specific generation ability of URLLM in comparison to state-of-the-art baselines. Our code is available at https://github.com/TingJShen/URLLM

Hyperspectral Anomaly Detection with Self-Supervised Anomaly Prior

The majority of existing hyperspectral anomaly detection (HAD) methods use the low-rank representation (LRR) model to separate the background and anomaly components, where the anomaly component is optimized by handcrafted sparse priors (e.g., $\ell_{2,1}$-norm). However, this may not be ideal since they overlook the spatial structure present in anomalies and make the detection result largely dependent on manually set sparsity. To tackle these problems, we redefine the optimization criterion for the anomaly component in the LRR model with a self-supervised network called self-supervised anomaly prior (SAP). This prior is obtained by the pretext task of self-supervised learning, which is customized to learn the characteristics of hyperspectral anomalies. Specifically, this pretext task is a classification task to distinguish the original hyperspectral image (HSI) and the pseudo-anomaly HSI, where the pseudo-anomaly is generated from the original HSI and designed as a prism with arbitrary polygon bases and arbitrary spectral bands. In addition, a dual-purified strategy is proposed to provide a more refined background representation with an enriched background dictionary, facilitating the separation of anomalies from complex backgrounds. Extensive experiments on various hyperspectral datasets demonstrate that the proposed SAP offers a more accurate and interpretable solution than other advanced HAD methods.

A Unified Framework for Adaptive Representation Enhancement and Inversed Learning in Cross-Domain Recommendation

Cross-domain recommendation (CDR), aiming to extract and transfer knowledge across domains, has attracted wide attention for its efficacy in addressing data sparsity and cold-start problems. Despite significant advances in representation disentanglement to capture diverse user preferences, existing methods usually neglect representation enhancement and lack rigorous decoupling constraints, thereby limiting the transfer of relevant information. To this end, we propose a Unified Framework for Adaptive Representation Enhancement and Inversed Learning in Cross-Domain Recommendation (AREIL). Specifically, we first divide user embeddings into domain-shared and domain-specific components to disentangle mixed user preferences. Then, we incorporate intra-domain and inter-domain information to adaptively enhance the ability of user representations. In particular, we propose a graph convolution module to capture high-order information, and a self-attention module to reveal inter-domain correlations and accomplish adaptive fusion. Next, we adopt domain classifiers and gradient reversal layers to achieve inversed representation learning in a unified framework. Finally, we employ a cross-entropy loss for measuring recommendation performance and jointly optimize the entire framework via multi-task learning. Extensive experiments on multiple datasets validate the substantial improvement in the recommendation performance of AREIL. Moreover, ablation studies and representation visualizations further illustrate the effectiveness of adaptive enhancement and inversed learning in CDR.

EfficientMFD: Towards More Efficient Multimodal Synchronous Fusion Detection

Multimodal image fusion and object detection play a vital role in autonomous driving. Current joint learning methods have made significant progress in the multimodal fusion detection task combining the texture detail and objective semantic information. However, the tedious training steps have limited its applications to wider real-world industrial deployment. To address this limitation, we propose a novel end-to-end multimodal fusion detection algorithm, named EfficientMFD, to simplify models that exhibit decent performance with only one training step. Synchronous joint optimization is utilized in an end-to-end manner between two components, thus not being affected by the local optimal solution of the individual task. Besides, a comprehensive optimization is established in the gradient matrix between the shared parameters for both tasks. It can converge to an optimal point with fusion detection weights. We extensively test it on several public datasets, demonstrating superior performance on not only visually appealing fusion but also favorable detection performance (e.g., 6.6% mAP50:95) over other state-of-the-art approaches.

Leveraging Computer Vision in the Intensive Care Unit (ICU) for Examining Visitation and Mobility

Despite the importance of closely monitoring patients in the Intensive Care Unit (ICU), many aspects are still assessed in a limited manner due to the time constraints imposed on healthcare providers. For example, although excessive visitations during rest hours can potentially exacerbate the risk of circadian rhythm disruption and delirium, it is not captured in the ICU. Likewise, while mobility can be an important indicator of recovery or deterioration in ICU patients, it is only captured sporadically or not captured at all. In the past few years, the computer vision field has found application in many domains by reducing the human burden. Using computer vision systems in the ICU can also potentially enable non-existing assessments or enhance the frequency and accuracy of existing assessments while reducing the staff workload. In this study, we leverage a state-of-the-art noninvasive computer vision system based on depth imaging to characterize ICU visitations and patients' mobility. We then examine the relationship between visitation and several patient outcomes, such as pain, acuity, and delirium. We found an association between deteriorating patient acuity and the incidence of delirium with increased visitations. In contrast, self-reported pain, reported using the Defense and Veteran Pain Rating Scale (DVPRS), was correlated with decreased visitations. Our findings highlight the feasibility and potential of using noninvasive autonomous systems to monitor ICU patients.